Anti-platelet effect of cumanastatin 1, a disintegrin isolated from venom of South American Crotalus rattlesnake

Thrombosis Research

Volumn 123, Issue 5, 2009, Pages 731-739

  Da Silva, Manuel ^a   Lucena, Sara ^a   Aguilar, Irma ^b   Rodríguez Acosta, Alexis ^b   Salazar, Ana M ^a   Sánchez, Elda E ^c   Girón, Maria E ^b   Carvajal, Zoila ^a   Arocha Piñango, Carmen L ^a   Guerrero, Belsy ^a  

^a INSTITUTO VENEZOLANO DE INVESTIGACIONES CIENTÍFICAS   (Venezuela)

^b UNIVERSIDAD CENTRAL DE VENEZUELA   (Venezuela)

^c TEXAS A AND M UNIVERSITY KINGSVILLE   (United States)

Author keywords

Crotalus durissus cumanensis mass spectrometry; Disintegrin; hemostasis; platelet adhesion; platelet aggregation; rattlesnakes

Indexed keywords

ADENOSINE DIPHOSPHATE; ANTITHROMBOCYTIC AGENT; COLLAGEN; CUMANASTATIN 1; DISINTEGRIN; FIBRINOGEN; FIBRINOGEN RECEPTOR; FIBRONECTIN; INTEGRIN; MATRIX PROTEIN; SEPHADEX; SNAKE VENOM; THROMBIN; UNCLASSIFIED DRUG; VERY LATE ACTIVATION ANTIGEN 5;

ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG ISOLATION; DRUG RECEPTOR BINDING; HUMAN; HUMAN CELL; IC 50; MOLECULAR WEIGHT; PRIORITY JOURNAL; PROTEIN BINDING; THROMBOCYTE ADHESION; THROMBOCYTE AGGREGATION INHIBITION;

ADULT; ANIMALS; CROTALID VENOMS; CROTALUS; DISINTEGRINS; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; MOLECULAR WEIGHT; PLATELET ADHESIVENESS; PLATELET AGGREGATION; PLATELET AGGREGATION INHIBITORS; PLATELET GLYCOPROTEIN GPIIB-IIIA COMPLEX;

EID: 60449091849     PISSN: 00493848     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.thromres.2008.08.001     Document Type: Article

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