Adjunctive steroids for tuberculous meningitis - More evidence, more questions

New England Journal of Medicine

Volumn 351, Issue 17, 2004, Pages 1792-1794

  Quagliarello, Vincent ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CORTICOSTEROID; DEXAMETHASONE; FIBRINOLYTIC AGENT; HEPARIN DERIVATIVE; STEROID; TUBERCULIN; TUBERCULOSTATIC AGENT; GLUCOCORTICOID; IMMUNOLOGICAL ADJUVANT;

CLINICAL FEATURE; CLINICAL TRIAL; DIRECTLY OBSERVED THERAPY; EDITORIAL; HUMAN; PREVALENCE; PRIORITY JOURNAL; TUBERCULOSIS; TUBERCULOUS MENINGITIS; AIDS RELATED COMPLEX; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; MORTALITY; NOTE;

ADJUVANTS, IMMUNOLOGIC; AIDS-RELATED OPPORTUNISTIC INFECTIONS; DEXAMETHASONE; GLUCOCORTICOIDS; HIV INFECTIONS; HUMANS; TUBERCULOSIS, MENINGEAL;

EID: 6044273446     PISSN: 00284793     EISSN: None     Source Type: Journal    
DOI: 10.1056/NEJMe048223     Document Type: Editorial

References (11)

1. World Health Organization. Fact Sheet N104. Tuberculosis. March 2004. (Accessed October 1, 2004, at http://www.who.int/mediacentre/factsheets/fs104/ en.)
2. Idem. Global tuberculosis control: Vietnam. WHO report 2004. (Accessed October 1, 2004, athttp://www.who.int/tb/publications/ global_report/2004/en/ VietNam.pdf.)
3. Rich AR, McCordock HA. The pathogenesis of tuberculous meningitis. Bull Johns Hopkins Hosp 1933;52:5-37.
4. Hosoglu S, Geyik MF, Balik I, et al. Predictors of outcome in patients with tuberculous meningitis. Int J Tuberc Lung Dis 2002;6:64-70.
5. St Hill CA, Rjfey C, Gifford JH. Use of intrathecal heparin in conjunction with streptomycin in treatment of tuberculous meningitis: preliminary report. J Clin Pathol 1948;1:157-61.
6. Smith HV, Vollum RL. Effects of intrathecal tuberculin and streptomycin in tuberculous meningitis: interim report. Lancet 1950;2:275-86.
7. Cathie IA. Bacterial fibrinolysin, its possible therapeutic application in tuberculous meningitis. J Clin Pathol 1949;2:73-6.
8. Shane SJ, Riley C. Tuberculous meningitis: combined therapy with cortisone and antimicrobial agents. N Engl J Med 1953;249:829-34.
9. O'Toole RD, Thornton GF, Mukherjee MK, Nath RL. Dexamethasone in tuberculous meningitis: relationship of cerebrospinal fluid effects to therapeutic efficacy. Ann Intern Med 1969;70:39-48.
10. Dooley DP, Carpenter JL, Rademacher S. Adjunctive corticosteroid therapy for tuberculosis: a critical reappraisal of the literature. Clin Infect Dis 1997;25:872-87.
11. Thwaites GE, Nguyen DB, Nguyen HD, et al. Dexamethasone for the treatment of tuberculous meningitis in adolescents and adults. N Engl J Med 2004;351:1741-51.