FR901228, a novel histone deacetylase inhibitor, induces cell cycle arrest and subsequent apoptosis in refractory human pancreatic cancer cells.

International journal of oncology

Volumn 24, Issue 3, 2004, Pages 679-685

  Sato, Nariatsu ^a   Ohta, Tetsuo ^a   Kitagawa, Hirohisa ^a   Kayahara, Masato ^a   Ninomiya, Itasu ^a   Fushida, Sachio ^a   Fujimura, Takashi ^a   Nishimura, Gen Ichi ^a   Shimizu, Koichi ^a   Miwa, Koichi ^a  

^a KANAZAWA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC ANTIBIOTIC; BIRC5 PROTEIN, HUMAN; CASP3 PROTEIN, HUMAN; CASPASE; CASPASE 3; CDKN1A PROTEIN, HUMAN; COLORING AGENT; CYCLIN DEPENDENT KINASE INHIBITOR 1A; CYCLINE; CYCLOPEPTIDE; DEPSIPEPTIDE; DNA FRAGMENT; ENZYME INHIBITOR; FR 901228; HISTONE; HISTONE DEACETYLASE; MICROTUBULE ASSOCIATED PROTEIN; PHOSPHATIDYLSERINE; PROPIDIUM IODIDE; TETRAZOLIUM; THIAZOLE DERIVATIVE; THIAZOLYL BLUE; TUMOR PROTEIN;

APOPTOSIS; ARTICLE; BIOSYNTHESIS; CELL CYCLE; CELL CYCLE G1 PHASE; CELL CYCLE G2 PHASE; CELL DIVISION; CELL SURVIVAL; DOSE RESPONSE; DRUG ANTAGONISM; FLOW CYTOMETRY; HUMAN; IC 50; METABOLISM; PANCREAS TUMOR; TIME; TUMOR CELL LINE; WESTERN BLOTTING;

ANTIBIOTICS, ANTINEOPLASTIC; APOPTOSIS; BLOTTING, WESTERN; CASPASE 3; CASPASES; CELL CYCLE; CELL DIVISION; CELL LINE, TUMOR; CELL SURVIVAL; COLORING AGENTS; CYCLIN-DEPENDENT KINASE INHIBITOR P21; CYCLINS; DEPSIPEPTIDES; DNA FRAGMENTATION; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; FLOW CYTOMETRY; G1 PHASE; G2 PHASE; HISTONE DEACETYLASES; HISTONES; HUMANS; INHIBITORY CONCENTRATION 50; MICROTUBULE-ASSOCIATED PROTEINS; NEOPLASM PROTEINS; PANCREATIC NEOPLASMS; PEPTIDES, CYCLIC; PHOSPHATIDYLSERINES; PROPIDIUM; TETRAZOLIUM SALTS; THIAZOLES; TIME FACTORS;

MLCS; MLOWN;

EID: 6044264858     PISSN: 10196439     EISSN: None     Source Type: Journal    
DOI: 10.3892/ijo.24.3.679     Document Type: Article

References (0)