Analysis of the inheritance of white spotting and the evaluation of KIT and EDNRB as spotting loci in Dutch boxer dogs

Journal of Heredity

Volumn 95, Issue 6, 2004, Pages 526-531

  Van Hagen, M A E ^a   Van Der Kolk, J ^a   Barendse, M A M ^a   Imholz, S ^a   Leegwater, P A J ^a   Knol, B W ^a   Van Oost, B A ^a  

^a UTRECHT UNIVERSITY   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ENDOTHELIN B RECEPTOR; G PROTEIN COUPLED RECEPTOR; STEM CELL FACTOR;

ARTICLE; BLOOD ANALYSIS; CONTROLLED STUDY; DOG; GENE LOCUS; GENE SEGREGATION; GENETIC MARKER; HETEROZYGOSITY; HOMOZYGOTE; INHERITANCE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL;

ANIMALS; DOGS; FEMALE; GENOTYPE; HAIR COLOR; INHERITANCE PATTERNS; LINKAGE (GENETICS); MALE; MICROSATELLITE REPEATS; PEDIGREE; PHENOTYPE; POLYMORPHISM, GENETIC;

CANIS FAMILIARIS; MAMMALIA; SOLEIDAE;

EID: 6044260102     PISSN: 00221503     EISSN: None     Source Type: Journal    
DOI: 10.1093/jhered/esh083     Document Type: Article

References (30)

1. American Kennel Club, 1997. The complete dog book. Foster City, CA: Howell Book House.
2. Bennett DC and Lamoreux ML, 2003. The color loci of mice-a genetic century. Pigment Cell Res 16:333-344.
3. Bondurand N, Pingault V, Goerich DE, Lemort N, Sock E, Caignec CL, Wegner M, and Goossens M, 2000. The interaction among SOX10, PAX3 and MITF, three genes altered in Waardenburg syndrome. Hum Mol Genet 9:1907-1917.
4. Cattanach B. White boxers and deafness (visited/last modified on January 2001) http://clubs.akc.org/abc/white-deafness.htm.
5. Grosz M and MacNeil M, 1999. The "spotted" locus maps to bovine chromosome 6 in a Hereford-cross population. J Hered 90:233-236.
6. Giuffra E, Evans G, Törnstein A, Wales R, Day A, Looft H, Plastow G, and Andersson L, 1999. The belt mutation in pigs is an allele at the dominant white (I/KIT) locus. Mamm Genome 10:1132-1136.
7. Guyon R, Lorentzen TD, Hitte C, Kim L, Cadieu E, Parker HG, Quignon P, Lowe JK, Renier C, Gelfenbeyn B, et al., 2003. A 1-Mb resolution radiation hybrid map of the canine genome. Proc Natl Acad Sci USA 100:5296-5301.
8. Hirooka H, de Koning DJ, van Arendonk JAM, Harlizius B, de Groot PN, and Bovenhuis H, 2002. Genome scan reveals new coat color loci in exotic pig crosses. J Hered 93:1-8.
9. Johansson Moller M, Chaudhary R, Hellmén E, Höyheim B, Chowdhary B, and Andersson L, 1996. Pigs with the dominant white coat color phenotype carry a duplication of the KIT gene encoding the mast/stem cell growth factor receptor. Mamm Genome 7:822-830.
10. Little CC, 1957. The inheritance of coat colours. New York: Comstock Publishing.
11. Marklund S, Kijas J, Rodriguez-Martinez H, R̈nnstrand L, Funa K, Moller M, Lange M, Edfors-Lilja I, and Andersson L, 1998. Molecular basis for the dominant white phenotype in the domestic pig. Genome Res 8:826-833.
12. Metallinos D and Rine J, 2000. Exclusion of EDNRB and KIT as the basis for white spotting in border collies. Genome Biology (a web-based only journal) http://www.genomebiology.com/2000/1/2/research/0004/.
13. Metallinos DL, Bowling AT, and Rine J, 1998. A missense mutation in the endothelin-B receptor gene is associated with lethal white foal syndrome: an equine version of Hirschsprung disease. Mamm Genome 9:426-431.
14. Miller SA, Dykes DD, and Polesky HF, 1988. A simple salting out procedure for extracting DNA from human nucleated cells. Nucleic Acids Res 16:1215.
15. Getting WS and Bennett DC. Mouse coat color genes (visited/last modified on January 7, 2004) http://www.cbc.med.umn.edu/ifpcs/micemut.htm.
16. Olsen H, Våge D, Lien S, and Klungland H, 2000. A DNA polymorphism in the bovine c-kit gene. Anim Genet 31:71.
17. Pielberg G, Olsson C, Syvanen AC, and Andersson L, 2002. Unexpectedly high allelic diversity at the KIT locus causing dominant white color in the domestic pig. Genetics 160:305-311.
18. Potterf SB, Furumura M, Dunn KJ, Arnheiter H, and Pavan WJ, 2000. Transcription factor hierarchy in Waardenburg syndrome: regulation of MITF expression by SOX10 and PAX3. Hum Genet 107:1-6.
19. Rawls JF, Mellgren EM, and Johnson SL, 2001. How the zebrafish gets its stripes. Dev Biol 240:301-314.
20. Reinsch N, Thomsen H, Xu N, Brink M, Looft C, Kalm E, Brockmann G, Grupe S, Kühn C, Schwerin M, et al., 1999. A QTL for the degree of spotting in cattle shows synteny with the KIT locus on chromosome 6. J Hered 90:629-634.
21. Rhim H, Dunn KJ, Aronzon A, Mac S, Cheng M, Lamoreux ML, Tilghman SM, and Pavan WJ, 2000. Spatially restricted hypopigmentation associated with an Ednrbs-modifying locus on mouse chromosome 10. Genome Res 10:17-29.
22. Robinson R, 1990. Genetics for dog breeders, 2nd ed. Oxford: Pergamon Press; 109-145.
23. Robinson R, 1998. Head spot and dilute mutations in the Norway rat. J Hered 89:100-101.
24. Schmutz SM, Berryere TG, Ellinwood NM, Kerns JA, and Barsh GS, 2003. MC1R studies in dogs with melanistic mask or brindle pattern. J Hered 94:69-73.
25. Silvers WK, 1979. The coat colors of mice: a model for mammalian gene action and interaction. New York: Springer-Verlag.
26. Spritz RA and Beighton P, 1998. Piebaldism with deafness: molecular evidence for an expanded syndrome. Am J Med Genet 75:101-103.
27. Strain GM, 1999. Congenital deafness and its recognition. Vet Clin N Am Small Anim Pract 29:895-907.
28. Woolf CM, 1992. Common white facial markings in Arabian horses that are homozygous and heterozygous for alleles at the A and E loci. J Hered 83:73-77.
29. Wu M, Hemesath TJ, Takemoto CM, Horstmann MA, Wells AG, Price ER, Fisher DZ, and Fisher DE, 2000. c-KIT triggers dual phosphorylations, which couple activation and degradation of the essential melanocyte factor Mi. Genes Dev 14:301-312.
30. Zemke D and Yuzbasiyan-Gurkan V, 1999. A single nucleotide polymorphism and a (GA)n microsatellite in intron 6 of the canine endothelin receptor B (EDNRB) gene. Anim Genet 30:390.