Spontaneous aggregation of leukocytes in active ulcerative colitis might be ICAM-1 dependent

Inflammation Research

Volumn 53, Issue 9, 2004, Pages 458-461

  Vainer, B ^a   Berliner, S ^b   Nielsen, O H ^a  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b TEL AVIV SOURASKY MEDICAL CENTER   (Israel)

Author keywords

Colitis; ICAM 1; Integrins; Leukocyte aggregation; Ulcerative

Indexed keywords

BETA2 INTEGRIN; CD11B ANTIGEN; FORMYLMETHIONYLLEUCYLPHENYLALANINE; INTERCELLULAR ADHESION MOLECULE 1; LIPOPOLYSACCHARIDE; MESALAZINE;

ADULT; AGED; ANALYZER; ARTICLE; AUTOMATION; BACTERIUM; BLOOD SAMPLING; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; EVALUATION; FEMALE; HUMAN; IMAGE ANALYSIS; LEUKOCYTE ADHERENCE; LEUKOCYTE AGGREGATION; MALE; NEUTROPHIL; OBSERVATION; STATISTICAL SIGNIFICANCE; STIMULATION; ULCERATIVE COLITIS;

ADULT; AGED; ANTIGENS, CD18; CELL ADHESION; CELL AGGREGATION; COLITIS, ULCERATIVE; FEMALE; HUMANS; INTERCELLULAR ADHESION MOLECULE-1; MALE; MIDDLE AGED; NEUTROPHIL ACTIVATION; NEUTROPHILS;

EID: 6044253490     PISSN: 10233830     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00011-004-1280-2     Document Type: Article

References (11)

1. Vainer B, Nielsen OH. Chemotactic properties of ICAM-1 and PECAM-1 on neutrophil granulocytes in ulcerative colitis: Effects of prednisolone and mesalazine. Aliment Pharmacol Ther 2000; 14: 1023-32.
2. 2 integrin-blocking in ICAM-1-mediated neutrophil migration in ulcerative colitis. Scand J Gastroenterol 2001; 36: 621-9.
3. Vainer B, Sørensen S, Nielsen OH, Horn T. Subcellular localization of intercellular adhesion molecule-1 (ICAM-1) in colonic mucosa in ulcerative colitis. Ultrastruct Pathol 2002; 26: 113-21.
4. Mishra L, Mishra BB, Harris M, Bayless TM, Muchmore AV. In vitro cell aggregation and cell adhesion molecules in Crohn's disease. Clin Exp Immunol 1994; 96: 432-6.
5. Arber N, Berliner S, Hallak A, Bujanover Y, Dotan I, Liberman E et al. Increased leucocyte adhesiveness/aggregation is a most useful indicator of disease activity in patients with inflammatory bowel disease. Gut 1995; 37: 77-80.
6. Berliner AS, Shapira I, Rogowski O, Sadees N, Rotstein R, Fusman R et al. Combined leukocyte and erthrocyte aggregation in the peripheral venous blood during sepsis. An indication of commonly shared adhesive protein(s). Int J Clin Lab Res 2000; 30: 27-31.
7. Rotstein R, Zeltser D, Fusman R, Shapira I, Urbach J, Bornstein N et al. The inflammation meter (INFLAMET): A new diagnostic approach to reveal the presence of an inflammatory response and assess its intensity. Isr Med Assoc J 2000; 2: 476-7.
8. Fusman R, Zeltser D, Rotstein R, Chapman J, Avitzour D, Shapira I et al. INFLAMET: An image analyzer to display erythrocyte adhesiveness/aggregation. Eur J Int Med 2000; 11: 271-6.
9. Allan RN, Rhodes JM, Hanauer SB, Keighley MRB, Alexander-Williams J, Fazio VW. Inflammatory bowel diseases. 3rd ed. New York: Churchill Livingstone, 1997.
10. Binder V. A comparison between clinical state, macroscopic and microscopic appearances of rectal mucosa, and cytological picture of mucosal exudates in ulcerative colitis. Scand J Gastroenterol 1970; 5: 627-32.
11. Rotstein R, Fusman R, Zeltser D, Shapira I, Shabtai E, Avitzour D et al. The picture of inflammation: a new concept that combines the white blood cell count and erythrocyte sedimentation rate into a new hematologic diagnostic modality. Acta Haematol 2001, 106: 106-14.