The effect of repeated exposures to low-dose UV radiation on the apoptosis of peripheral blood mononuclear cells

Archives of Dermatology

Volumn 145, Issue 2, 2009, Pages 133-138

  Narbutt, Joanna ^a   Cebula, Barbara ^a   Lesiak, Aleksandra ^a   Sysa Jedrzejowska, Anna ^a   Norval, Mary ^b   Robak, Tadeusz ^a   Smolewski, Piotr ^a  

^a MEDICAL UNIVERSITY OF LODZ   (Poland)

^b UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN BAX; PROTEIN BCL 2; PROTEIN MCL 1; PROTEIN P73;

ADULT; APOPTOSIS; ARTICLE; COHORT ANALYSIS; CONTROLLED STUDY; DOWN REGULATION; FEMALE; HUMAN; HUMAN CELL; MALE; NORMAL HUMAN; PERIPHERAL BLOOD MONONUCLEAR CELL; POLAND; PRIORITY JOURNAL; PROTEIN EXPRESSION; RADIATION DOSE; RADIATION EXPOSURE; RADIATION RESPONSE; SOLAR RADIATION; ULTRAVIOLET B RADIATION; ULTRAVIOLET RADIATION; UNIVERSITY; WHOLE BODY RADIATION;

ADULT; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; FEMALE; HUMANS; IMMUNITY, CELLULAR; IN SITU NICK-END LABELING; LEUKOCYTES, MONONUCLEAR; MALE; MIDDLE AGED; RADIATION DOSAGE; SKIN; ULTRAVIOLET RAYS; WHOLE-BODY IRRADIATION; YOUNG ADULT;

EID: 60349130567     PISSN: 0003987X     EISSN: 15383652     Source Type: Journal    
DOI: 10.1001/archdermatol.2008.574     Document Type: Article

References (32)

1. Raj D, Brash DE, Grossman D. Keratinocyte apoptosis in epidermal development and disease. J Invest Dermatol. 2006;126(2):243-257.
2. Smolewski P, Darzynkiewicz Z, Robak T. Caspase-mediated cell death in hematological malignancies: theoretical considerations, methods of assessment and clinical implications. Leuk Lymphoma. 2003;44(7):1089-1104.
3. Zhou P, Qian L, Kozopas KM, Craig RW. Mcl-1, a Bcl-2 family member delays of death of hematopoietic cells under variety of apoptosis-inducing conditions. Blood. 1997;89(2):630-643.
4. Zhivotovsky B, Samali A, Gahm A, Orrenius S. Caspases: their intracellular localization and translocation during apoptosis. Cell Death Differ. 1999;6(7):644-651.
5. Norbury CJ, Zhivotovsky B. DNA damage-induced apoptosis. Oncogene. 2004;23(16):2797-2808.
6. Wolf R, Matz H, Ruocco E, Ruocco V. The putative role of apoptosis in the induction of pemphigus. Med Hypotheses. 2005;64(1):44-45.
7. Zhivotovsky B, Orrenius S. Carcinogenesis and apoptosis: paradigms and paradoxes. Carcinogenesis. 2006;27(10):1939-1945.
8. Li G, Tron V, Ho V. Induction of squamous cell carcinoma in p53 deficient mice after ultraviolet irradiation. J Invest Dermatol. 1998;110(1):72-75.
9. Clydesdale GJ, Dandie GW, Muller HK. Ultraviolet light induced injury: immunological and inflammatory effects. Immunol Cell Biol. 2001;79(6):547-568.
10. Schwarz T. Mechanisms of UV-induced immunosuppression. Keio J Med. 2005;54(4):165-171.
11. Ullrich SE. Mechanisms underlying UV-induced immune suppression. Mutat Res. 2005;571(1-2):185-205.
12. Narbutt J, Lesiak A, Skibinska M, et al. Suppression of contact hypersensitivity after repeated exposures of humans to low doses of solar simulated radiation. Photochem Photobiol Sci. 2005;4(7):517-522.
13. Narbutt J, Lesiak A, Sysa-Jedrzejowska A, et al. Repeated low-dose ultraviolet (UV) B exposures of humans induce limited photoprotection against the immune effects of erythemal UVB radiation. Br J Dermatol. 2007;156(3):539-547.
14. Haake AR, Polakowska RR. Cell death by apoptosis in epidermal biology. J Invest Dermatol. 1993;101(2):107-112.
15. Okamoto H, Mizuno K, Itoh T, Tanaka K, Horio T. Evaluation of apoptotic cells induced by ultraviolet light B radiation in epidermal sheets stained by the TUNEL technique. J Invest Dermatol. 1999;113(5):802-807.
16. Liu M, Dhanwada KR, Birt DF, Hecht S, Pelling JC. Increase in p53 protein half life in mouse keratinocytes following UV-B irradiation. Carcinogenesis. 1994;15(6):1089-1092.
17. Hill LL, Ouhtit A, Loughlin SM, Kripke ML, Ananthaswamy HN, Owen-Schaub LB. Fas ligand: a sensor for DNA damage critical in skin cancer etiology. Science. 1999;285(5429):898-900.
18. Brash DE, Wikonkal NM, Remenyik E, et al. The DNA damage signal for Mdm2 regulation, Trp53 induction and sunburn cell formation in vivo originates from actively transcribed genes. J Invest Dermatol. 2001;117(5):1234-1240.
19. Narbutt J, Skibinska M, Lesiak A, et al. Exposure to low doses of solar simulated radiation induces an increase in the myeloid subtype of blood dendritic cells. Scand J Immunol. 2004;60(4):429-435.
20. Narbutt J, Lesiak A, Skibinska M, et al. Repeated doses of UVR cause minor alteration in cytokine serum levels in humans. Mediators Inflamm. 2005;2005(5):298-303.
21. Fitzpatrick TB. The validity and practicality of sun-reactive skin types I through VI. Arch Dermatol. 1988;124(6):869-871.
22. Tuchinda C, Lim HW, Strickland FM, Guzmán EA, Wong HK. Comparison of broadband UVB, narrowband UVB, broadband UVA and UVA1 on activation of apoptotic pathways in human peripheral blood mononuclear cells. Photodermatol Photoimmunol Photomed. 2007;23(1):2-9.
23. Darzynkiewicz Z, Bedner E, Smolewski P. In situ detection of DNA strand breaks in analysis of apoptosis by flow- and laser-scanning cytometry. Methods Mol Biol. 2002;203:69-77.
24. Lazebnik YA, Kaufmann SH, Desnoyers S, Poirier GG, Earnshaw WC. Cleavage of poly (ADPribose) polymerase by a proteinase with properties like ICE. Nature. 1994;371(6495):346-347.
25. Johnson R, Staiano-Coico L, Austin L, Cardinale I, Nabeya-Tsukifuji R, Krueger JG. PUVA treatment selectively induces a cell cycle block and subsequent apoptosis in human T-lymphocytes. Photochem Photobiol. 1996;63(5):566-571.
26. CaricchioR, Reap EA, Cohen PL. Fas/Fas ligand interactions are involved in ultraviolet-B-induced human lymphocytes apoptosis. J Immunol. 1998;161(1):241-251.
27. Kern PM, Keilholz L, Forster C, et al. UVB-irradiated T-cells undergoing apoptosis lose L-selectin by metalloprotease-mediated shedding. Int J Radiat Biol. 2000;76(9):1265-1271.
28. Breuckmann F, von Kobyletzki G, Avermaete A, et al. Mechanisms of apoptosis: UVA1-induced immediate and UVB-induced delayed apoptosis in human T cells in vitro. J Eur Acad Dermatol Venereol. 2003;17(4):418-429.
29. Wikonkal NM, Remenyik E, Knezevic D, et al. Inactivating E2f1 reverts apoptosis resistance and cancer sensitivity in Trp53-deficient mice. Nat Cell Biol. 2003;5(7):655-660.
30. Yamada Y, Yasui H, Sakurai H. Suppressive effect of caffeic acid and its derivatives on the generation of UVA-induced reactive oxygen species in the skin of hairless mice and pharmacokinetic analysis on organ distribution of caffeic acid in ddY mice. Photochem Photobiol. 2006;82(6):1668-1676.
31. Kelly DA, Walker SL, McGregor JM, Young AR. A single exposure of solar simulated radiation suppresses contact hypersensitivity responses both locally and systemically in humans: quantitative studies with high-frequency ultrasound. J Photochem Photobiol B. 1998;44(2):130-142.
32. Norval M, McLoone P, Lesiak A, Narbutt J. The effect of chronic ultraviolet radiation on the human immune system. Photochem Photobiol. 2008;84(1):19-28.