Willingness to participate in preventive HIV vaccine trials in a community-based cohort in south western Uganda

Tropical Medicine and International Health

Volumn 14, Issue 2, 2009, Pages 196-203

  Ruzagira, Eugene ^a   Wandiembe, Symon ^a   Bufumbo, Leonard ^a   Levin, Jonathan ^a   Price, Matthew A ^b   Grosskurth, Heiner ^a,c   Kamali, Anatoli ^a  

^a UGANDA VIRUS RESEARCH INSTITUTE   (Uganda)

^b INTERNATIONAL AIDS VACCINE INITIATIVE   (United States)

^c LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE   (United Kingdom)

Author keywords

Barriers; Community based; HIV vaccine trial; Willingness

Indexed keywords

HUMAN IMMUNODEFICIENCY VIRUS VACCINE; PLACEBO;

BLOOD; COHORT ANALYSIS; HUMAN IMMUNODEFICIENCY VIRUS; PARTICIPATORY APPROACH; PREGNANCY; QUESTIONNAIRE SURVEY; VACCINATION;

ADULT; ARTICLE; BEHAVIOR; BLOOD SAMPLING; CLINICAL TRIAL; COHORT ANALYSIS; COMMUNITY CARE; CONFIDENCE INTERVAL; CONTROLLED STUDY; COOPERATION; DATA ANALYSIS; DRUG EFFECT; DRUG TARGETING; FEMALE; FOLLOW UP; HEALTH SURVEY; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; MAJOR CLINICAL STUDY; MALE; PREGNANCY; QUESTIONNAIRE; RISK ASSESSMENT; RISK FACTOR; SEXUAL BEHAVIOR; STATISTICAL SIGNIFICANCE; TREATMENT DURATION; UGANDA; VIRUS TRANSMISSION;

ADOLESCENT; ADULT; AIDS VACCINES; CLINICAL TRIALS AS TOPIC; CONSUMER PARTICIPATION; CROSS-SECTIONAL STUDIES; FEMALE; HEALTH KNOWLEDGE, ATTITUDES, PRACTICE; HIV INFECTIONS; HUMANS; MALE; MIDDLE AGED; MOTIVATION; QUESTIONNAIRES; UGANDA; YOUNG ADULT;

EID: 60349128724     PISSN: 13602276     EISSN: 13653156     Source Type: Journal    
DOI: 10.1111/j.1365-3156.2008.02200.x     Document Type: Article

References (21)

1. Buchbinder SP, Metch B, Holte SE, Scheer S, Coletti A Vittinghoff E (2004) Determinants of enrolment in preventive HIV vaccine trial. Hypothetical versus actual willingness and barriers to participation. Journal of Acquired Immune Deficiency Syndromes 36, 604 612.
2. HIV Vaccine Trials Network (2007) Press Release on STEP Trial. Available at: http://www.hvtn.org/pdf/FINAL-HIV-Vaccine-Press-Release.pdf (accessed on 7 January 2009).
3. International AIDS Vaccine Initiative (2006) AIDS Vaccine Blue Print: Actions to Strengthen Global Research and Development. International AIDS Vaccine Initiative, New York.
4. Jenkins RA, Torugsa K, Markowitz LE et al. (2000) Willingness to participate in HIV-1 vaccine trials among young Thai men. Sexually Transmitted Infections 76, 386 392.
5. Kiwanuka N, Robb M, Kigozi G et al. (2004) Knowledge about vaccines and willingness to participate in preventive HIV vaccine Trials. A population based study, Rakai, Uganda. Journal of Acquired Immune Deficiency Syndromes 36, 721 725.
6. MacQueen KM, Johnson L, Alleman P, Akumatey B, Lawoyin T Nyiama T (2007) Pregnancy prevention practices among women with multiple partners in an HIV prevention trial. Journal of Acquired Immune Deficiency Syndromes 46, 32 38.
7. Mcgrath JW, George K, Svilar G et al. (2001) Knowledge about vaccine trials and willingness to participate in an HIV/AIDS vaccine study in the Ugandan military. Journal of Acquired Immune Deficiency Syndromes 27, 381 388.
8. Molyneux C, Peshu N Marsh K (2005a) Trust and informed consent: insights from community members on the Kenyan coast. Social Science & Medicine 61, 1463 1473.
9. Molyneux C, Wassenaar D, Peshu N Marsh K (2005b) 'Even if they ask you to stand by a tree all day, you will have to do it (laughter).': community voices on the notion and practice of informed consent for biomedical research in developing countries. Social Science & Medicine 61, 443 454.
10. Moodley K (2007) Microbicide research in developing countries: have we given the ethical concerns due consideration? BMC Medical Ethics 8 doi :, 1 7.
11. Newman PA, Duan N, Roberts KJ et al. (2006) HIV vaccine trial participation among ethnic minority communities. Barriers, motivators, and implications for recruitment. Journal of Acquired Immune Deficiency Syndromes 41, 210 217.
12. Newman PA, Duan N, Lee S et al. (2007) Willingness to participate in HIV vaccine trials: the impact of trial attributes. Preventive Medicine 44, 554 557.
13. Périssé ARS, Schechter M, Moreira RI et al. (2000) Willingness to participate in HIV vaccine trials among men who have sex with men in Rio de Janeiro, Brazil. Journal of Acquired Immune Deficiency Syndromes 25, 459 463.
14. Ruzagira E, Kamali A, Bwanika A, Bahemuka U, Price M Grosskurth H (2006) HIV incidence and risk factors for HIV transmission in an HIV vaccine feasibility study in Rural Uganda. XVI International AIDS Conference, Toronto, Canada, MOPE0340.
15. Sahay S, Mehendale S, Sane S et al. (2005) Correlates of HIV vaccine trial participation: an Indian perspective. Vaccine 23, 1351 1358.
16. Sherr L, Bolding G Elford J (2004) Recruiting London gay men into an HIV vaccine trial: is it feasible? AIDS Care 16, 565 571.
17. Souza CT, Lowndes CM, Szwarcwald CL, Sutmöller F Bastos FI (2003) Willingness to participate in HIV vaccine trials among a sample of men who have sex with men, with and without a history of commercial sex, Rio de Janeiro, Brazil. AIDS Care 15, 539 548.
18. UNAIDS/WHO (2007) AIDS Epidemic Update. UNAIDS, Geneva.
19. Van de Ven P, Mao L, Crawford J et al. (2005) Willingness to participate in HIV vaccine trials among HIV-negative gay men in Sydney, Australia. International Journal of STD & AIDS 16, 314 317.
20. Weinhardt LS, Forsyth AD, Carey MP, Jaworsiki BC Durant LE (1998) Reliability and validity of self-report measures of HIV-related sexual behavior: progress since 1990 and recommendations for research and practice. Archives of Sexual Behavior 27, 155 180.
21. Yin L, Zhang Y, Qian H et al. (2008) Willingness of Chinese injection drug users to participate in HIV vaccine Trials. Vaccine 26, 762 768.