Bupropion as a possible treatment option for restless legs syndrome

Annals of Pharmacotherapy

Volumn 43, Issue 2, 2009, Pages 370-374

  Lee, Jennifer J ^a,b,d   Erdos, Joseph ^c   Wilkosz, Meghan F ^c   LaPlante, Renee ^a   Wagoner, Brenda ^a  

^a UNIVERSITY OF CONNECTICUT   (United States)

^b VA CONNECTICUT HEALTHCARE SYSTEM   (United States)

^c VETERANS AFFAIRS MEDICAL CENTER   (United States)

^d NONE   (United States)

Author keywords

Bupropion; Restless legs syndrome

Indexed keywords

ALPRAZOLAM; AMFEBUTAMONE; CALCIUM; CARBIDOPA PLUS LEVODOPA; CLONAZEPAM; ESCITALOPRAM; GABAPENTIN; LAMOTRIGINE; LEVOTHYROXINE; LORAZEPAM; OXCARBAZEPINE; PRAMIPEXOLE; QUETIAPINE; ROPINIROLE; TEMAZEPAM; TRAMADOL; TRAZODONE; VALPROATE SEMISODIUM; ZALEPLON; ZOLPIDEM;

ADULT; AKATHISIA; ANAMNESIS; ANXIETY; ARTICLE; BEDTIME DOSAGE; BIPOLAR II DISORDER; BULIMIA; CASE REPORT; DEPRESSION; DIZZINESS; DRUG DOSE REDUCTION; DRUG DOSE TITRATION; DRUG EFFICACY; DRUG RESPONSE; DRUG SUBSTITUTION; DRUG TOLERABILITY; DRUG TREATMENT FAILURE; DRUG WITHDRAWAL; DYSKINESIA; EVENING DOSAGE; FEMALE; GASTROINTESTINAL SYMPTOM; HUMAN; INSOMNIA; LETHARGY; MORNING DOSAGE; OCULOGYRIC CRISIS; PHARMACIST; PRIORITY JOURNAL; PRURITUS; PSYCHIATRIST; RESTLESS LEGS SYNDROME; SIDE EFFECT; SLEEP DISORDER; SWEATING; TREATMENT RESPONSE; UNSPECIFIED SIDE EFFECT; WEIGHT GAIN;

EID: 60349127558     PISSN: 10600280     EISSN: None     Source Type: Journal    
DOI: 10.1345/aph.1L035     Document Type: Article

References (19)

1. NHLBI. Restless legs syndrome: detection and management in primary care. Am Fam Physician 2000;62:108-14.
2. Scienta Healthcare Education. Restless legs syndrome: diagnosis and treatment strategies for the primary care provider. www.iafp.com/pdfs/ RLS%20Guideline.pdf (accessed 2008 Apr 14).
3. Martin CM. The mysteries of restless legs syndrome. Consul Pharm 2007;22:907-24.
4. Karatas M. Restless legs syndrome and periodic limb movements during sleep: diagnosis and treatment. Neurologist 2007;13:294-301.
5. Silber MH, Ehrenberg BL, Allen RP, et al. An algorithm for the management of restless legs syndrome. Mayo Clin Proc 2004;79:916-22.
6. Schapira AHV. Restless legs syndrome: an update on treatment options. Drugs 2004;64:149-58.
7. Comella CL. Restless legs syndrome. Treatment with dopaminergic agents. Neurology 2002;58:S87-92.
8. RLS Foundation. RLS medical bulletin 2005. www.rls.org (accessed 2008 Apr 14).
9. Allen RP, Picchietti D, Hening WA, et al. Restless legs syndrome: diagnostic criteria, special considerations, and epidemiology. A report from the restless legs syndrome diagnosis and epidemiology workshop at the National Institutes of Health. Sleep Med 2003;4:101-19.
10. Ryan M, Slevin JT. Restless legs syndrome. Am J Health Syst Pharm 2006;63:1599-612.
11. Boehringer Ingelheim. Mirapex (pramipexole dihydrochloride). www.mirapex.com (accessed 2008 May 2).
12. GlaxoSmithKline. Requip (ropinirole). www.requip.com (accessed 2008 May 2).
13. Garcia-Borreguero D, Larrosa O, de la Llave Y, Verger K, Masramon X, Hernandez G. Treatment of restless legs syndrome with gabapentin: a double-blind, cross-over study. Neurology 2002;59:1573-9.
14. Telstad W, Sorensen O, Larsen S, Lillevold PE, Stensrud P, Nyberg-Hansen R. Treatment of the restless legs syndrome with carbamazepine: a double blind study. Br Med J 1984;288:444-6.
15. Walters AS, Wagner ML, Hening WA, et al. Successful treatment of idiopathic restless legs syndrome in a randomized double-blind trial of oxycodone versus placebo. Sleep 1993;16:327-32.
16. Laurma H, Markkula J. Treatment of restless legs syndrome with tramadol: an open study. J Clin Psychiatry 1999;60:241-4.
17. Kenney C, Kuo SH, Jimenez-Shahed J. Tourette's syndrome. Am Fam Physician 2008;77:651-60.
18. Kim SW, Shin IS, Kim JM, Yang SJ, Shin HY, Yoon JS. Bupropion may improve restless legs syndrome. A report of three cases. Clin Neuropharmacol 2005;28:298-301.
19. Nofzinger EA, Fasiczka A, Berman S, Thase ME. Bupropion SR reduces periodic limb movements associated with arousals from sleep in depressed patients with periodic limb movement disorder. J Clin Psychiatry 2000;61:858-62.