Effect of inflammatory responses in microglia induced by oligomeric β-amyloid1-42 on neuronal cells

Acta Anatomica Sinica

Volumn 39, Issue 6, 2008, Pages 804-809

  Pan, Xiao Dong ^a   Chen, Xiao Chun ^a   Zhu, Yuan Gui ^a   Chen, Li Min ^a   Zhang, Jing ^a  

^a FUJIAN MEDICAL UNIVERSITY   (China)

Author keywords

Alzheimer disease; Conditioned media; Microglia; Mouse; Neuroinflammation; Neuron; Oligomeric amyloid peptide1 42

Indexed keywords

AMYLOID BETA PROTEIN; CYCLOOXYGENASE 2; INTERLEUKIN 1BETA; NITRIC OXIDE SYNTHASE; PROSTAGLANDIN E2; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL COUNT; CELL CULTURE; CELL DEATH; CELL VIABILITY; CELLULAR DISTRIBUTION; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; EPIFLUORESCENCE MICROSCOPY; INFLAMMATION; MICROGLIA; NONHUMAN; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; WESTERN BLOTTING;

EID: 60349121806     PISSN: 05291356     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (17)

1. Akiyama H, Barger S, Barnum S, et al. Inflammation and Alzheimer's disease[J]. Neurobiol Aging, 2000,21(3):383-421.
2. Cotman CW, Tenner AJ, Cummings BJ. β-Amyloid converts an acute phase injury response to chronic injury responses[J]. Neurobiol Aging, 1996, 17(5): 723-731.
3. Dahlgren KN, Manelli AM, Stine WB Jr, et al. Oligomeric and fibrillar species of amyloid-beta peptides differentially affect neuronal viability [J]. J Biol Chem, 2002,277(35):32046-32053.
4. White JA, Manelli AM, Holmberg KH, et al. Differential effects of oligomeric and fibrillar amyloid-beta 1-42 on astrocyte-mediated inflammation[J]. Neurobiol Dis, 2005,18(3):459-465.
5. Tamagno E, Bardini P, Guglielmotto M, et al. The various aggregation states of beta-amyloid 1-42 mediate different effects on oxidative stress, neurodegeneration, and BACE-1 expression[J]. Free Radic Biol Med, 2006,41(2):202-212.
6. Cui YH, Le Y, Zhang X, et al. Up-regulation of FPR2, a chemotactic receptor for amyloid beta 1-42, in murine microglial cells by TNF alpha [J]. Neurobiol Dis, 2002, 10(3):366-377.
7. Yan SD, Chen X, Fu J, et al. RAGE and amyloid-beta peptide neurotoxicity in Alzheimer's disease[J], Nature, 1996,382(6593): 685-691.
8. McDonald DR, Bamberger ME, Combs CK, et al. β-Amyloid flbrils activate parallel mitogen-activated protein kinase pathways in microglia and THP1 monocytes[J]. J Neurosci, 1998,18(12): 4451-4460.
9. El Khoury J, Hickman SE, Thomas CA, et al. Scavenger receptor-mediated adhesion of microglia to beta-amyloid fibrils[J]. Nature, 1996, 382(6593):716-719.
10. Combs CK, Karlo JC, Kao SC, et al. beta-Amyloid stimulation of microglia and monocytes results in TNFalpha-dependent expression of inducible nitric oxide synthase and neuronal apoptosis[J]. J Neurosci, 2001, 21(4): 1179-1188.
11. Floden AM, Li S, Combs CK. Beta-amyloid-stimulated microglia induce neuron death via synergistic stimulation of tumor necrosis factor alpha and NMDA receptors[J]. J Neurosci, 2005,25(10):2566-2575.
12. Schubert P, Rudolphi K. Interfering with the pathologic activation of microglial cells and astrocytes in dementia [J]. Alzheimer Dis Assoc Disord, 1998, 12 (Suppl 2), S21-28.
13. Lee SC, Dickson DW, Brosnan CF. Interleukin-1, nitric oxide and reactive astrocytes[J]. Brain Behav Immun, 1995,9(4):345-354.
14. Lee P, Son D, Lee J, et al. Excessive production of nitric oxide induces the neuronal cell death in lipopolysaccharide-treated rat hippocampal slice culture[J]. Neurosci Lett, 2003, 349(1): 33-36.
15. He Y, Imam SZ, Dong Z, et al. Role of nitric oxide in rotenone-induced nigro-striatal injury[J]. J Neurochem, 2003, 86(6): 1338-1345.
16. Munch G, Gasic-Milenkovic J, Dukic-Stefanovic S, et al. Microglial activation induces cell death, inhibits neurite outgrowth and causes neurite retraction of differentiated neuroblastoma cells[J]. Exp Brain Res, 2003, 150(1):1-8.
17. Kawano T, Anrather J, Zhou P. Prostaglandin E2 EP1 receptors: downstream effectors of COX-2 neurotoxicity[J]. Nat Med, 2006, 12 (2):225-229.