Alternate phase variation in expression of two major surface membrane proteins (MBA and UU376) of Ureaplasma parvum serovar 3

FEMS Microbiology Letters

Volumn 292, Issue 2, 2009, Pages 187-193

  Zimmerman, Carl Ulrich R ^a   Stiedl, Thomas ^a   Rosengarten, Renate ^a   Spergser, Joachim ^a  

^a UNIVERSITY OF VETERINARY MEDICINE   (Austria)

Author keywords

Antigenic variation; Multiple banded antigen; Phase variation; Selective antibody pressure; Ureaplasma; UU376

Indexed keywords

ANTISERUM; DNA; MEMBRANE PROTEIN; MULTIPLE BANDED ANTIGEN; POLYCLONAL ANTIBODY; PROTEIN MBA; PROTEIN UPVMP376; PROTEIN UU376; UNCLASSIFIED DRUG;

ARTICLE; BACTERIAL GENE; BACTERIAL STRAIN; GENE LOCUS; GENE SWITCHING; MBA GENE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; SEROTYPE; SOUTHERN BLOTTING; UREAPLASMA; UREAPLASMA PARVUM; UREAPLASMA UREALYTICUM; UU375 GENE; UU376 GENE; WESTERN BLOTTING;

ANTIGENIC VARIATION; ANTIGENS, BACTERIAL; BLOTTING, SOUTHERN; DNA, BACTERIAL; GENE ORDER; HUMANS; INFANT, NEWBORN; MEMBRANE PROTEINS; MODELS, BIOLOGICAL; MOLECULAR SEQUENCE DATA; RECOMBINATION, GENETIC; SEQUENCE ANALYSIS, DNA; UREAPLASMA;

UREAPLASMA; UREAPLASMA PARVUM; UREAPLASMA PARVUM SEROVAR 3; UREAPLASMA UREALYTICUM;

EID: 60349115205     PISSN: 03781097     EISSN: 15746968     Source Type: Journal    
DOI: 10.1111/j.1574-6968.2009.01505.x     Document Type: Article

References (22)

1. Abele-Horn M, Peters J, Genzel-Boroviczény O, Wolff C, Zimmermann A Gottschling W (1997) Vaginal Ureaplasma urealyticum colonization: influence on pregnancy outcome and neonatal morbidity. Infection 25 : 286 291.
2. Bhugra B Dybvig K (1992) High-frequency rearrangements in the chromosome of Mycoplasma pulmonis correlate with phenotypic switching. Mol Microbiol 6 : 1149 1154.
3. Bhugra B, Voelker LL, Zou N, Yu H Dybvig K (1995) Mechanism of antigenic variation in Mycoplasma pulmonis: interwoven, site-specific DNA inversions. Mol Microbiol 18 : 703 714.
4. Cassell GH, Waites KB, Watson HL, Crouse DT Harasawa R (1993) Ureaplasma urealyticum intrauterine infection: role in prematurity and disease in newborns. Clin Microbiol Rev 6 : 69 87.
5. Chopra-Dewasthaly R, Marenda M, Rosengarten R, Jechlinger W Citti C (2005) Construction of the first shuttle vectors for gene cloning and homologous recombination in Mycoplasma agalactiae. FEMS Microbiol Lett 253 : 89 94.
6. Chopra-Dewasthaly R, Citti C, Glew MD, Zimmermann M, Rosengarten R Jechlinger W (2008) Phase-locked mutants of Mycoplasma agalactiae: defining the molecular switch of high-frequency Vpma antigenic variation. Mol Microbiol 67 : 1196 1210.
7. Dumke R, Catrein I, Pirkil E, Herrmann R Jacobs E (2003) Subtyping of Mycoplasma pneumoniae isolates based on extended genome sequencing and on expression profiles. Int J Med Microbiol 292 : 513 525.
8. Glass JI, Lefkowitz EJ, Glass JS, Heiner CR, Chen EY Cassell GH (2000) The complete sequence of the mucosal pathogen Ureaplasma urealyticum. Nature 407 : 757 762.
9. Glew MD, Papazisi L, Poumarat F, Bergonier D, Rosengarten R Citti C (2000) Characterization of a multigene family undergoing high frequency DNA rearrangements and coding for abundant variable surface proteins in Mycoplasma agalactiae. Infect Immun 68 : 4539 4548.
10. Gray DJ, Robinson HB, Malone J Thomson Jr. RB (1992) Adverse outcome in pregnancy following amniotic fluid isolation of Ureaplasma urealyticum. Prenatal Diagn 12 : 111 117.
11. Kiarie MN, Rurangirwa FR, Perryman LE, Jasmer DP McGuire TC (1996) Monoclonal antibodies to surface-exposes proteins of Mycoplasma mycoides subsp. mycoides (small-colony strain), which causes contagious bovine pleuropneumonia. Clin Diagn Lab Immun 3 : 746 752.
12. Lysnyansky I, Ron Y Yogev D (2001) Juxtaposition of an active promoter to vsp genes via site-specific DNA inversions generates antigenic variation in Mycoplasma bovis. J Bacteriol 183 : 5698 5708.
13. Monecke S, Helbig JH Jacobs E (2003) Phase variation of the multiple banded protein in Ureaplasma urealyticum and Ureaplasma parvum. Int J Med Microbiol 293 : 203 211.
14. Naessens A, Foulon W, Cammu H, Goossens A Lauwers S (1987) Epidemiology and pathogenesis of Ureaplasma urealyticum in spontaneous abortion and early preterm labor. Acta Obstet Gyn Scan 66 : 513 516.
15. Ruhnke HL Rosendal S (1994) Useful protocols for diagnosis of animal mycoplasmas. Mycoplasmosis in Animals: Laboratory Diagnosis (Whitford HW, Rosenbusch RF Lauerman LH, eds), pp. 151 152. Iowa State University Press, Ames, IA.
16. Sambrook J, Fritsch EF Maniatis T (1989) Molecular Cloning: A Laboratory Manual, 2nd edn. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
17. Sarg B, Helliger W, Talasz H, Förg B Lindner HH (2006) Histone H1 phosphorylation occurs site-specifically during interphase and mitosis: identification of a novel phosphorylation site on histone H1. J Biol Chem 281 : 6573 6580.
18. Teng LJ, Zheng X, Glass JI, Watson HL, Tsai J Cassell GH (1994) Ureaplasma urealyticum biovar specificity and diversity are encoded in multiple-banded antigen gene. J Clin Microbiol 32 : 1464 1469.
19. Vogel I, Thorsen P, Hogan VK, Schieve LA, Jacobsson B Ferre CD (2006) The joint effect of vaginal Ureaplasma urealyticum and bacterial vaginosis on adverse pregnancy outcomes. Acta Obstet Gyn Scan 85 : 778 785.
20. Yoon BH, Chang JW Romero R (1998) Isolation of Ureaplasma urealyticum from the amniotic cavity and adverse outcome in preterm labor. Obstet Gynecol 92 : 77 82.
21. Zheng X, Teng LJ, Glass JI, Blanchard A, Cao Z, Kempf MC, Watson HL Cassell GH (1994) Size variation of a major serotype-specific antigen of Ureaplasma urealyticum. Ann NY Acad Sci 730 : 299 301.
22. Zheng X, Teng LJ, Watson HL, Glass JI, Blanchard A Cassell GH (1995) Small repeating units within the Ureaplasma urealyticum MB antigen gene encode serovar specificity and are associated with antigen size variation. Infect Immun 63 : 891 898.