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Volumn 43, Issue 2, 2009, Pages 322-328

Warfarin-antiretroviral interactions

Author keywords

Antiretrovirals; Drug interactions; Nonnucleoside reverse transcriptase inhibitor; Protease inhibitor; Warfarin

Indexed keywords

ABACAVIR; ANTIRETROVIRUS AGENT; ATAZANAVIR; CHEMOKINE RECEPTOR CCR5 ANTAGONIST; CYTOCHROME P450 2C9; DARUNAVIR; DELAVIRDINE; DIDANOSINE; EFAVIRENZ; EMTRICITABINE; ETRAVIRINE; INDINAVIR; INTEGRASE INHIBITOR; LAMIVUDINE; LOPINAVIR PLUS RITONAVIR; NELFINAVIR; NEVIRAPINE; PROTEINASE INHIBITOR; RITONAVIR; RNA DIRECTED DNA POLYMERASE INHIBITOR; SAQUINAVIR; STAVUDINE; TENOFOVIR; WARFARIN; ZIDOVUDINE;

EID: 60349110009     PISSN: 10600280     EISSN: None     Source Type: Journal    
DOI: 10.1345/aph.1L497     Document Type: Review
Times cited : (41)

References (44)
  • 1
    • 47649115323 scopus 로고    scopus 로고
    • Life expectancy of individuals on combination antiretroviral therapy in high-income countries: A collaborative analysis of 14 cohort studies
    • The Antiretroviral Therapy Cohort Collaboration, DOI 10.1016/S0140-6736(08)61113-7
    • The Antiretroviral Therapy Cohort Collaboration. Life expectancy of individuals on combination antiretroviral therapy in high-income countries: a collaborative analysis of 14 cohort studies. Lancet 2008;372:293-9. DOI 10.1016/S0140-6736(08)61113-7
    • (2008) Lancet , vol.372 , pp. 293-299
  • 2
    • 33748116898 scopus 로고    scopus 로고
    • Mortality in the highly active antiretroviral therapy era: Changing causes of death and disease in the HIV Outpatient Study
    • DOI 10.1097/01.qai.0000233310.90484.16
    • Pallela FJ Jr, Baker RK, Moorman AC, et al. Mortality in the highly active antiretroviral therapy era: changing causes of death and disease in the HIV Outpatient Study. J Aquir Immune Defic Syndr 2006;43:27-34. DOI 10.1097/01.qai.0000233310.90484.16
    • (2006) J Aquir Immune Defic Syndr , vol.43 , pp. 27-34
    • Pallela Jr, F.J.1    Baker, R.K.2    Moorman, A.C.3
  • 3
    • 0042832397 scopus 로고    scopus 로고
    • Guidelines for the evaluation and management of dyslipidemia in human immunodeficiency virus (HIV)-infected adults receiving antiretroviral therapy: Recommendations of the HIV Medical Association of the Infectious Disease Society of America and the Adult AIDS Clinical Trials Group
    • DOI 10.1086/378131
    • Dubé MP, Stein JH, Aberg JA, et al. Guidelines for the evaluation and management of dyslipidemia in human immunodeficiency virus (HIV)-infected adults receiving antiretroviral therapy: recommendations of the HIV Medical Association of the Infectious Disease Society of America and the Adult AIDS Clinical Trials Group. Clin Infect Dis 2003;37:613-27. DOI 10.1086/378131
    • (2003) Clin Infect Dis , vol.37 , pp. 613-627
    • Dubé, M.P.1    Stein, J.H.2    Aberg, J.A.3
  • 4
    • 45949101991 scopus 로고    scopus 로고
    • Hirsh J, Guyatt G, Albers GW, Harrington R, Schünemann HJ. Antithrombotic and thrombolytic therapy: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th ed.). Chest 2008;133(6 suppl):71S-198S. DOI 10.1378/chest.08-0693
    • Hirsh J, Guyatt G, Albers GW, Harrington R, Schünemann HJ. Antithrombotic and thrombolytic therapy: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th ed.). Chest 2008;133(6 suppl):71S-198S. DOI 10.1378/chest.08-0693
  • 5
    • 0035951474 scopus 로고    scopus 로고
    • Need for increased dose of warfarin in HIV patients taking nevirapine
    • DOI 10.1097/00002030-200101260-00021
    • Dionisio D, Mininni S, Bartolozzi D, Esperti F, Vivarelli A, Leoncini F. Need for increased dose of warfarin in HIV patients taking nevirapine. AIDS 2001;15:277-8. DOI 10.1097/00002030-200101260-00021
    • (2001) AIDS , vol.15 , pp. 277-278
    • Dionisio, D.1    Mininni, S.2    Bartolozzi, D.3    Esperti, F.4    Vivarelli, A.5    Leoncini, F.6
  • 6
    • 45749145161 scopus 로고    scopus 로고
    • Possible antiretroviral therapy-warfarin drug interaction
    • DOI 10.1592/phco.28.7.945
    • Fulco PP, Zingone MM, Higginson RT. Possible antiretroviral therapy-warfarin drug interaction. Pharmacotherapy 2008;28:945-9. DOI 10.1592/phco.28.7.945
    • (2008) Pharmacotherapy , vol.28 , pp. 945-949
    • Fulco, P.P.1    Zingone, M.M.2    Higginson, R.T.3
  • 7
    • 39349087177 scopus 로고    scopus 로고
    • Drug interactions between warfarin and efavirenz or lopinavir-ritonavir in clinical treatment
    • DOI 10.1086/524086
    • Bonora S, Lanzafame M, D'Avolio A, et al. Drug interactions between warfarin and efavirenz or lopinavir-ritonavir in clinical treatment. Clin Infect Dis 2008;46:146-7. DOI 10.1086/524086
    • (2008) Clin Infect Dis , vol.46 , pp. 146-147
    • Bonora, S.1    Lanzafame, M.2    D'Avolio, A.3
  • 9
    • 0032425376 scopus 로고    scopus 로고
    • Potential interaction involving warfarin and ritonavir
    • DOI 10.1345/aph.17456
    • Knoell KR, Young TM, Cousins ES. Potential interaction involving warfarin and ritonavir. Ann Pharmacother 1998;32:1299-302. DOI 10.1345/aph.17456
    • (1998) Ann Pharmacother , vol.32 , pp. 1299-1302
    • Knoell, K.R.1    Young, T.M.2    Cousins, E.S.3
  • 10
    • 34548355091 scopus 로고    scopus 로고
    • Interaction between lopinavir/ritonavir and warfarin
    • DOI 10.1503/cmaj.061284
    • Hughes CA, Freitas A, Miedzinski LJ. Interaction between lopinavir/ritonavir and warfarin. CMAJ 2007;177:357-9. DOI 10.1503/cmaj.061284
    • (2007) CMAJ , vol.177 , pp. 357-359
    • Hughes, C.A.1    Freitas, A.2    Miedzinski, L.J.3
  • 11
    • 0033397061 scopus 로고    scopus 로고
    • Ritonavir and warfarin interaction
    • DOI 10.1097/00002030-199909100-00028
    • Newshan G, Tsang P. Ritonavir and warfarin interaction. AIDS 1999; 13:1788-9. DOI 10.1097/00002030-199909100-00028
    • (1999) AIDS , vol.13 , pp. 1788-1789
    • Newshan, G.1    Tsang, P.2
  • 12
    • 0031008490 scopus 로고    scopus 로고
    • Hypoprothrombinemia during concomitant therapy with warfarin and saquinavir (letter)
    • Darlington MR. Hypoprothrombinemia during concomitant therapy with warfarin and saquinavir (letter). Ann Pharmacother 1997;31:647.
    • (1997) Ann Pharmacother , vol.31 , pp. 647
    • Darlington, M.R.1
  • 13
    • 0016220245 scopus 로고
    • Studies on the optical enantiomorphs of warfarin in man
    • O'Reilly RA. Studies on the optical enantiomorphs of warfarin in man. Clin Pharmacol Ther 1974;16:348-54.
    • (1974) Clin Pharmacol Ther , vol.16 , pp. 348-354
    • O'Reilly, R.A.1
  • 15
    • 0026519541 scopus 로고
    • Hydroxylation of warfarin by human cDNA-expressed cytochrome P-450: A role for P-4502C9 in the etiology of (S)-warfarin-drug interactions
    • DOI 10.1021/tx00025a009
    • Rettie AE, Korzekwa KR, Kunze KL, et al. Hydroxylation of warfarin by human cDNA-expressed cytochrome P-450: a role for P-4502C9 in the etiology of (S)-warfarin-drug interactions. Chem Res Toxicol 1992; 5:54-9. DOI 10.1021/tx00025a009
    • (1992) Chem Res Toxicol , vol.5 , pp. 54-59
    • Rettie, A.E.1    Korzekwa, K.R.2    Kunze, K.L.3
  • 16
    • 0031015345 scopus 로고    scopus 로고
    • Human P450 metabolism of warfarin
    • DOI 10.1016/s0163-7258(96)00140-4
    • Kaminsky LS, Zhang Z-Y. Human P450 metabolism of warfarin. Pharmacol Ther 1997;73:67-74. DOI 10.1016/s0163-7258(96)00140-4
    • (1997) Pharmacol Ther , vol.73 , pp. 67-74
    • Kaminsky, L.S.1    Zhang, Z.-Y.2
  • 17
    • 0031931102 scopus 로고    scopus 로고
    • Protease inhibitors as inhibitors of human cytochromes P450: High risk associated with ritonavir
    • von Moltke LL, Greenblatt DJ, Grassi JM, et al. Protease inhibitors as inhibitors of human cytochromes P450: high risk associated with ritonavir. J Clin Pharmacol 1998;38:106-11.
    • (1998) J Clin Pharmacol , vol.38 , pp. 106-111
    • von Moltke, L.L.1    Greenblatt, D.J.2    Grassi, J.M.3
  • 18
    • 0034747669 scopus 로고    scopus 로고
    • Inhibition of human cytochrome P450 isoforms by nonnucleoside reverse transcriptase inhibitors
    • von Moltke LL, Greenblatt DJ, Granda BW, et al. Inhibition of human cytochrome P450 isoforms by nonnucleoside reverse transcriptase inhibitors. J Clin Pharmacol 2001;41:85-91.
    • (2001) J Clin Pharmacol , vol.41 , pp. 85-91
    • von Moltke, L.L.1    Greenblatt, D.J.2    Granda, B.W.3
  • 19
    • 34748887980 scopus 로고    scopus 로고
    • Dixit V, Hariparsad N, Li F, Desai P, Thummel KE, Unadkat JD. Cytochrome P450 enzymes and transporters induced by anti-human immunodeficiency virus protease inhibitors in human hepatocytes: implications for predicting clinical drug interactions. Drug Metab Dispos 2007;35:1853-9. Epub 2007 Jul 16. DOI 10.1124/dmd.107.016089
    • Dixit V, Hariparsad N, Li F, Desai P, Thummel KE, Unadkat JD. Cytochrome P450 enzymes and transporters induced by anti-human immunodeficiency virus protease inhibitors in human hepatocytes: implications for predicting clinical drug interactions. Drug Metab Dispos 2007;35:1853-9. Epub 2007 Jul 16. DOI 10.1124/dmd.107.016089
  • 20
    • 33745433348 scopus 로고    scopus 로고
    • Lopinavir/ritonavir induces the hepatic activity of cytochrome P450 enzymes CYP2C9, CYP2C19, and CYP1A2 but inhibits the hepatic and intestinal activity of CYP3A as measured by a phenotyping drug cocktail in healthy volunteers
    • Yeh RF, Gaver VE, Patterson KB, et al. Lopinavir/ritonavir induces the hepatic activity of cytochrome P450 enzymes CYP2C9, CYP2C19, and CYP1A2 but inhibits the hepatic and intestinal activity of CYP3A as measured by a phenotyping drug cocktail in healthy volunteers. J Acquir Immune Defic Syndr 2006;42:52-60.
    • (2006) J Acquir Immune Defic Syndr , vol.42 , pp. 52-60
    • Yeh, R.F.1    Gaver, V.E.2    Patterson, K.B.3
  • 21
    • 60349095242 scopus 로고    scopus 로고
    • Product information. Selzentry (maraviroc). New York, NY: Pfizer Labs, August 2007.
    • Product information. Selzentry (maraviroc). New York, NY: Pfizer Labs, August 2007.
  • 23
    • 31344451857 scopus 로고    scopus 로고
    • Different contributions of polymorphisms in VKORC1and CYP2C9 to intra- and inter-population differences in maintenance dose of warfarin in Japanese, Caucasians and African-Americans
    • Takahashi H, Wilkinson GR, Nutescu EA, et al. Different contributions of polymorphisms in VKORC1and CYP2C9 to intra- and inter-population differences in maintenance dose of warfarin in Japanese, Caucasians and African-Americans. Pharmacogenet Genomics 2006;16:101-10.
    • (2006) Pharmacogenet Genomics , vol.16 , pp. 101-110
    • Takahashi, H.1    Wilkinson, G.R.2    Nutescu, E.A.3
  • 24
    • 33645849823 scopus 로고    scopus 로고
    • Influence of coagulation factor, vitamin K epoxide reductase complex subunit 1, and cytochrome P450 2C9 gene polymorphisms on warfarin dose requirements
    • DOI 10.1016/j.clpt.2005.11.011
    • Aquilante CL, Langaee TY, Lopez LM, et al. Influence of coagulation factor, vitamin K epoxide reductase complex subunit 1, and cytochrome P450 2C9 gene polymorphisms on warfarin dose requirements. Clin Pharmacol Ther 2006;79:291-302. DOI 10.1016/j.clpt.2005.11.011
    • (2006) Clin Pharmacol Ther , vol.79 , pp. 291-302
    • Aquilante, C.L.1    Langaee, T.Y.2    Lopez, L.M.3
  • 25
    • 84868894459 scopus 로고    scopus 로고
    • Human Cytochrome P450 Allele Nomenclature Committee, accessed 2008 Jul 18
    • Human Cytochrome P450 Allele Nomenclature Committee. www.cypalleles.ki. se/cyp2c9.htm (accessed 2008 Jul 18).
  • 26
    • 33747861061 scopus 로고    scopus 로고
    • Pharmacokinetic drug interactions with non-nucleoside reverse transcriptase inhibitors
    • DOI 10.1517/17425255.1.3.473
    • Ma Q, Okusanya O, Smith P, et al. Pharmacokinetic drug interactions with non-nucleoside reverse transcriptase inhibitors. Expert Opin Drug Metab Toxicol 2005;1:473-85. DOI 10.1517/17425255.1.3.473
    • (2005) Expert Opin Drug Metab Toxicol , vol.1 , pp. 473-485
    • Ma, Q.1    Okusanya, O.2    Smith, P.3
  • 27
    • 60349121357 scopus 로고    scopus 로고
    • Product information. Intelence (etravirine). Raritan, NJ: Tibotec Therapeutics, January 2008.
    • Product information. Intelence (etravirine). Raritan, NJ: Tibotec Therapeutics, January 2008.
  • 28
    • 60349106466 scopus 로고    scopus 로고
    • Product information. Viracept (nelfinavir). La Jolla, CA: Agouron Pharmaceuticals, August 2007.
    • Product information. Viracept (nelfinavir). La Jolla, CA: Agouron Pharmaceuticals, August 2007.
  • 29
    • 60349093015 scopus 로고    scopus 로고
    • Product information. Kaletra (lopinavir/ritonavir). North Chicago, IL: Abbott Laboratories, November 2007.
    • Product information. Kaletra (lopinavir/ritonavir). North Chicago, IL: Abbott Laboratories, November 2007.
  • 30
    • 60349099098 scopus 로고    scopus 로고
    • Product information. Norvir (ritonavir). North Chicago, IL: Abbott Laboratories, May 2007.
    • Product information. Norvir (ritonavir). North Chicago, IL: Abbott Laboratories, May 2007.
  • 31
    • 60349129127 scopus 로고    scopus 로고
    • Product information. Prezista (darunavir). Raritan, NJ: Tibotec Therapeutics, February 2008.
    • Product information. Prezista (darunavir). Raritan, NJ: Tibotec Therapeutics, February 2008.
  • 33
    • 0032983746 scopus 로고    scopus 로고
    • A generalized seizure following initiation of neifinavir in a patient with human immunodeficiency virus type I infection, suspected due to interaction between neifinavir and phenytoin
    • DOI 10.2169/internalmedicine.38.302
    • Honda M, Yasuoka A, Aoki M, Oka S. A generalized seizure following initiation of neifinavir in a patient with human immunodeficiency virus type I infection, suspected due to interaction between neifinavir and phenytoin. Intern Med 1999;38:302-3. DOI 10.2169/internalmedicine.38.302
    • (1999) Intern Med , vol.38 , pp. 302-303
    • Honda, M.1    Yasuoka, A.2    Aoki, M.3    Oka, S.4
  • 34
    • 60349115344 scopus 로고    scopus 로고
    • Cocktail study to investigate the in-vivo drug interaction potential of darunavir coadministered with low-dose ritonavir (DRV/r; RTV) on cytochrome P450 enzymes 2D6, 2C9 and 2C19
    • Presented at
    • Sekar V, Spinosa-Guzman S, Meyvisch P, et al. Cocktail study to investigate the in-vivo drug interaction potential of darunavir coadministered with low-dose ritonavir (DRV/r; RTV) on cytochrome P450 enzymes 2D6, 2C9 and 2C19. Presented at: 9th International Workshop on Clinical Pharmacology of HIV, 2008.
    • (2008) 9th International Workshop on Clinical Pharmacology of HIV
    • Sekar, V.1    Spinosa-Guzman, S.2    Meyvisch, P.3
  • 35
    • 60349103272 scopus 로고    scopus 로고
    • Product information. Aptivus (tipranavir). Ridgefield, CT: Boehringer Ingelheim Pharmaceuticals, June 2008.
    • Product information. Aptivus (tipranavir). Ridgefield, CT: Boehringer Ingelheim Pharmaceuticals, June 2008.
  • 36
    • 60349084902 scopus 로고    scopus 로고
    • Tipranavir. Antiviral Drugs Advisory Committee (AVDAC) briefing document, NDA 21-814. Ridgefield, CT: Boehringer Ingelheim Pharmaceuticals, Inc., 2005.
    • Tipranavir. Antiviral Drugs Advisory Committee (AVDAC) briefing document, NDA 21-814. Ridgefield, CT: Boehringer Ingelheim Pharmaceuticals, Inc., 2005.
  • 37
    • 60349103793 scopus 로고    scopus 로고
    • Product information. Reyataz (atazanavir). Princeton, NJ: Bristol-Myers Squibb Company, March 2008.
    • Product information. Reyataz (atazanavir). Princeton, NJ: Bristol-Myers Squibb Company, March 2008.
  • 38
    • 0030430035 scopus 로고    scopus 로고
    • Cytochrome P450-mediated metabolism of the HIV-1 protease inhibitor ritonavir (ABT-538) in human liver microsomes
    • Kumar GN, Rodrigues AD, Buko AM, Denissen JF. Cytochrome P450-mediated metabolism of the HIV-1 protease inhibitor ritonavir (ABT-538) in human liver microsomes. J Pharmacol Exp Ther 1996; 277:423-31.
    • (1996) J Pharmacol Exp Ther , vol.277 , pp. 423-431
    • Kumar, G.N.1    Rodrigues, A.D.2    Buko, A.M.3    Denissen, J.F.4
  • 39
    • 0030852009 scopus 로고    scopus 로고
    • Differential inhibition of cytochrome P450 isoforms by the protease inhibitors, ritonavir, saquinavir and indinavir
    • DOI 10.1046/j.1365-2125.1997.006
    • Eagling VA, Back DJ, Barry MG. Differential inhibition of cytochrome P450 isoforms by the protease inhibitors, ritonavir, saquinavir and indinavir. Br J Clin Pharmacol 1997;44:190-4. DOI 10.1046/j.1365-2125.1997.006
    • (1997) Br J Clin Pharmacol , vol.44 , pp. 190-194
    • Eagling, V.A.1    Back, D.J.2    Barry, M.G.3
  • 40
    • 60349098310 scopus 로고    scopus 로고
    • Product information. Invirase (saquinavir). Nutley, NJ: Roche Laboratories Inc., July 2007.
    • Product information. Invirase (saquinavir). Nutley, NJ: Roche Laboratories Inc., July 2007.
  • 41
    • 34249814621 scopus 로고    scopus 로고
    • Mechanisms of pharmacokinetic and pharmacodynamic drug interactions associated with ritonavir-enhanced tipranavir
    • DOI 10.1592/phco.27.6.888
    • Vourvahis M, Kashuba AD. Mechanisms of pharmacokinetic and pharmacodynamic drug interactions associated with ritonavir-enhanced tipranavir. Pharmacotherapy 2007;27:888-909. DOI 10.1592/phco.27.6.888
    • (2007) Pharmacotherapy , vol.27 , pp. 888-909
    • Vourvahis, M.1    Kashuba, A.D.2
  • 42
    • 60349120366 scopus 로고    scopus 로고
    • Panel on Antiretroviral Guidelines for Adults and Adolescents. Guidelines for the use of antiretroviral agents in HIV-1-infected adults and adolescents. Department of Health and Human Services. January 29, 2008;1-128. www.aidsinfo.nih.gov/ContentFiles/AdultandAdolescentGL.pdf (accessed 2008 Jul 3).
    • Panel on Antiretroviral Guidelines for Adults and Adolescents. Guidelines for the use of antiretroviral agents in HIV-1-infected adults and adolescents. Department of Health and Human Services. January 29, 2008;1-128. www.aidsinfo.nih.gov/ContentFiles/AdultandAdolescentGL.pdf (accessed 2008 Jul 3).
  • 43
    • 0030896237 scopus 로고    scopus 로고
    • Multiple-dose pharmacokinetics of ritonavir in human immunodeficiency virus-infected subjects
    • Hsu A, Granneman GR, Witt G, et al. Multiple-dose pharmacokinetics of ritonavir in human immunodeficiency virus-infected subjects. Antimicrob Agents Chemother 1997;41:898-905.
    • (1997) Antimicrob Agents Chemother , vol.41 , pp. 898-905
    • Hsu, A.1    Granneman, G.R.2    Witt, G.3


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