Improvement of deficient natural killer activity and delayed bactericidal activity by a thiol proteinase inhibitor, E-64-d, in leukocytes from Chediak-Higashi syndrome patients in vitro

International Immunopharmacology

Volumn 9, Issue 3, 2009, Pages 366-370

  Tanabe, Fuminori ^a   Kasai, Hirotake ^b   He, Limin ^b   Kin, Tomohiro ^c   Fujikado, Takashi ^d   Kumamoto, Toshihide ^e   Hara, Toshiro ^f   Iwata, Tsutomu ^g   Ito, Masahiko ^b  

^a Interdisciplinary Graduate School of Medicine and Engineering   (Japan)

^b Interdisciplinary Graduate School of Medicine and Engineering   (Japan)

^c Suita Municipal Hospital   (Japan)

^d OSAKA UNIVERSITY MEDICAL SCHOOL   (Japan)

^e OITA UNIVERSITY   (Japan)

^f KYUSHU UNIVERSITY   (Japan)

^g TOKYO KASEI UNIVERSITY   (Japan)

Author keywords

Bactericidal activity; Chediak Higashi syndrome; Natural killer activity; Protein kinase C

Indexed keywords

12 (2 CYANOETHYL) 6,7,12,13 TETRAHYDRO 13 METHYL 5 OXOINDOLO[2,3 A]PYRROLO[3,4 C]CARBAZOLE; ALOXISTATIN; CHELERYTHRINE; CONCANAVALIN A; ISOENZYME; PROTEIN KINASE C; PROTEINASE INHIBITOR;

ARTICLE; BACTERICIDAL ACTIVITY; CELLULAR IMMUNITY; CHEDIAK HIGASHI SYNDROME; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOLYSIS; DOSE RESPONSE; DOWN REGULATION; ENZYME ACTIVITY; FEMALE; HUMAN; HUMAN CELL; IN VITRO STUDY; INFECTION SENSITIVITY; LEUKOCYTE; MALE; NATURAL KILLER CELL; NONHUMAN; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; STAPHYLOCOCCUS AUREUS;

BENZOPHENANTHRIDINES; CARBAZOLES; CELL LINE, TUMOR; CHEDIAK-HIGASHI SYNDROME; CYSTEINE PROTEINASE INHIBITORS; FEMALE; HUMANS; KILLER CELLS, NATURAL; LEUCINE; MALE; PROTEIN KINASE C; PROTEIN KINASE INHIBITORS; STAPHYLOCOCCAL INFECTIONS; STAPHYLOCOCCUS AUREUS;

EID: 60249100731     PISSN: 15675769     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.intimp.2009.01.003     Document Type: Article

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