Enantiomeric separation of racemic 1-benzyl-N-methyltetrahydroisoquinolines on chiral columns and chiral purity determinations of the O-methylated metabolites in plant cell cultures by HPLC-CD on-line coupling in combination with HPLC-MS

Phytochemistry

Volumn 70, Issue 2, 2009, Pages 198-206

  Iwasa, Kinuko ^a   Doi, Yasuhiro ^a   Takahashi, Teturo ^a   Cui, Wenhua ^a   Nishiyama, Yumi ^a   Tode, Chisato ^a   Moriyasu, Masataka ^a   Takeda, Kazuyoshi ^b   Minami, Hiromichi ^c   Ikezawa, Nobuhiro ^d   Sato, Fumihiko ^d  

^a KOBE PHARMACEUTICAL UNIVERSITY   (Japan)

^b YOKOHAMA COLLEGE OF PHARMACY   (Japan)

^c ISHIKAWA PREFECTURAL UNIVERSITY   (Japan)

^d KYOTO UNIVERSITY   (Japan)

Author keywords

1 Benzyl N methyltetrahydroisoquinolines; Berberidaceae; Cell cultures; Chiral LC CD; Chiral LC MS; Corydalis platycarpa; Fumariaceae; Macleaya cordata; Nandina domestica; O Methylation; Optical purity; Papaveraceae

Indexed keywords

HYDROGEN; PLANT EXTRACT; QUINOLINE DERIVATIVE;

ARTICLE; CELL CULTURE; CHEMICAL STRUCTURE; CHEMISTRY; CIRCULAR DICHROISM; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; METABOLISM; METHYLATION; ONLINE SYSTEM; STEREOISOMERISM;

CELLS, CULTURED; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CIRCULAR DICHROISM; HYDROGEN; MASS SPECTROMETRY; METHYLATION; MOLECULAR STRUCTURE; ONLINE SYSTEMS; PLANT EXTRACTS; QUINOLINES; STEREOISOMERISM;

BERBERIDACEAE; CORYDALIS; FUMARIACEAE; MACLEAYA; MACLEAYA CORDATA; NANDINA; NANDINA DOMESTICA; PAPAVERACEAE;

EID: 60249100371     PISSN: 00319422     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.phytochem.2008.12.001     Document Type: Article

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