Comparing oral gabapentin versus clonidine as premedication on early postoperative pain, nausea and vomiting after general anesthesia

International Journal of Pharmacology

Volumn 4, Issue 2, 2008, Pages 153-156

  Mohammadi, Sussan Soltani ^a   Seyedi, Mirsadegh ^a  

^a TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

Clonidine; Gabapentin; Nausea; Pain; Postoperative; Vomiting

Indexed keywords

CLONIDINE; GABAPENTIN; MORPHINE; PLACEBO;

ABDOMINAL SURGERY; ADULT; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIZZINESS; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; DRUG RESPONSE; GENERAL ANESTHESIA; HUMAN; MAJOR CLINICAL STUDY; PAIN ASSESSMENT; POSTOPERATIVE CARE; POSTOPERATIVE NAUSEA AND VOMITING; POSTOPERATIVE PAIN; PREMEDICATION; RANDOMIZED CONTROLLED TRIAL; XEROSTOMIA;

EID: 60249095455     PISSN: 18117775     EISSN: 18125700     Source Type: Journal    
DOI: 10.3923/ijp.2008.153.156     Document Type: Article

References (9)

1. Eckhardt, K., S. Ammon, U. Hofman, A. Riebe, N. Gugeler and G. Mikus, 2000. Gabapentin enhances the analgesic effect of morphine in healthy volunteers. Anesth. Analg., 91 (1): 185-191.
2. Ghignone, M., O. Calvillo and L. Quintin, 1987. Anesthesia and hypertension: The effect of clonidine on preoperative hemodynamics and isoflurane requirements. Anesthesiology, 67 (1): 3-10.
3. Goa, K.L. and E.M. Sorkin, 1993. Gabapentin. A review of its pharmacological properties and clinical potential in epilepsy. Drugs, 46 (3): 409-427.
4. Guttuso, T.J., J. Roscoe and J. Griggs, 2003. Effect of gabapentin on nausea induced by chemotherapy in patients with breast cancer. Lancet, 361 (5): 1703-1705.
5. Mathiesen, O., S. Moiniche and J.B. Dahl, 2007 Gabapentin and postoperative pain: A qualitative and quantitative systematic review, with focus on procedure. BMC. Anesth., 6 (7): 1186/1471-2253-7-6.
6. Pandey, C.K., S. Priye, S.P. Ambesh, S. Singh U. Singh and P.K. Singh, 2006. Prophylactic Grabapentin for prevention postoperative nausea and vomiting in patients undergoing laparoscopic cholecystectomy: A randomized double-blinded placebo-controlled study. J. Postgrad. Med., 52 (2): 97-101.
7. Quintin, L., J.P. Viale, G. Annat, L. Quintin, J.P. Viale, G. Annat, J.P. Hoen, E. Butin, J.M. Cottet-Emard, J.C. Levron, D. Busserv and J.M.D. Motin, 1991. Oxygen uptake after major abdominal surgery: Effect of clonidine. Anesthesiology, 74 (2): 236-241.
8. Rose, M.A. and P.C. Kam, 2002. Grabapentin: Pharmacology and its use pain management. Anaesthesia, 57 (3): 451-462.
9. Turan, A., B. Karamanlioglu, D. Memis, P. Usar, Z. Pamukcu and M. Ture, 2004. The analgesic effects of gabapentin after total abdominal hysterectomy. Anesth. Analg., 98 (5): 1370-1373.