An application of a modified constrained randomization process to a practice-based cluster randomized trial to improve colorectal cancer screening

Contemporary Clinical Trials

Volumn 30, Issue 2, 2009, Pages 129-132

  Nietert, Paul J ^a   Jenkins, Ruth G ^b   Nemeth, Lynne S ^a   Ornstein, Steven M ^b  

^a MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

^b MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

Author keywords

Cluster randomized trials; Colorectal cancer screening; Covariate balance; Practice based research networks; Randomization techniques; Study design

Indexed keywords

ADULT; ARTICLE; CANCER SCREENING; CLINICAL PRACTICE; CLINICAL TRIAL; COLORECTAL CANCER; CONTROL GROUP; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; FEMALE; HUMAN; INTERVENTION STUDY; MALE; MEDICAL RESEARCH; OUTCOME ASSESSMENT; POPULATION; PRIMARY MEDICAL CARE; RANDOMIZATION; RANDOMIZED CONTROLLED TRIAL; SIMULATION; UNITED STATES; ALGORITHM; CLUSTER ANALYSIS; COLORECTAL NEOPLASMS; MASS SCREENING; MULTIVARIATE ANALYSIS; PRIMARY HEALTH CARE; PROCEDURES; RANDOMIZED CONTROLLED TRIAL (TOPIC); STANDARDS; STATISTICS AND NUMERICAL DATA;

ALGORITHMS; CLUSTER ANALYSIS; COLORECTAL NEOPLASMS; FEMALE; HUMANS; MALE; MASS SCREENING; MULTIVARIATE ANALYSIS; PRIMARY HEALTH CARE; RANDOMIZED CONTROLLED TRIALS AS TOPIC;

EID: 60249093402     PISSN: 15517144     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cct.2008.10.002     Document Type: Article

References (21)

1. Murray D.M. Design and Analysis of Group-Randomized Trials (1998), Oxford University Press, New York
2. Bland J.M. Cluster randomised trials in the medical literature: two bibliometric surveys. BMC Med Res Methodol 4 (2004) 21
3. Raab G.M., and Butcher I. Balance in cluster randomized trials. Stat Med 20 (2001) 351-365
4. Institute of Medicine. Crossing the Quality Chasm (2001), National Academy of Sciences, Washington, D.C.
5. Agency for Healthcare Research and Qualtiy. AHRQ Practice-Based Research Networks (PBRNs). Fact Sheet, June 2001 (revised May 2006). AHRQ Publication No. 01-P020. http://www.ahrq.gov/research/pbrn/pbrnfact.htm. Accessed 3-5-2008.
6. Berner E.S., Detmer D.E., and Simborg D. Will the wave finally break? A brief view of the adoption of electronic medical records in the United States. J Am Med Inform Assoc 12 (2005) 3-7
7. Moulton L.H. Covariate-based constrained randomization of group-randomized trials. Clin Trials 1 (2004) 297-305
8. Tamura R.N., Mills B.J., and Lovelace J.K. Constrained randomization in a therapeutic efficacy trial. Biometrics 49 (1993) 249-258
9. Berger V.W. A review of methods for ensuring the comparability of comparison groups in randomized clinical trials. Rev Recent Clin Trials 1 (2006) 81-86
10. Chaudhary M.A., and Moulton L.H. A SAS macro for constrained randomization of group-randomized designs. Comput Methods Programs Biomed 83 (2006) 205-210
11. Tiahrt K.J., and Weeks D.L. A method of constrained randomization for 2n factorials. Technometrics 12 (1970) 471-486
12. Pocock S.J., and Simon R. Sequential treatment assignment with balancing for prognostic factors in the controlled clinical trial. Biometrics 31 (1975) 103-115
13. Zucker D.M., Lakatos E., Webber L.S., et al. Statistical design of the Child and Adolescent Trial for Cardiovascular Health (CATCH): implications of cluster randomization. Control Clin Trials 16 (1995) 96-118
14. Piaggio G., Carroli G., Villar J., et al. Methodological considerations on the design and analysis of an equivalence stratified cluster randomization trial. Stat Med 20 (2001) 401-416
15. Gail M.H., Byar D.P., Pechacek T.F., and Corle D.K. Aspects of statistical design for the Community Intervention Trial for Smoking Cessation (COMMIT). Control Clin Trials 13 (1992) 6-21
16. Hayes R., Mosha F., Nicoll A., et al. A community trial of the impact of improved sexually transmitted disease treatment on the HIV epidemic in rural Tanzania: 1. Design. AIDS 9 (1995) 919-926
17. Wight D., Raab G.M., Henderson M., et al. Limits of teacher delivered sex education: interim behavioural outcomes from randomised trial. BMJ 324 (2002) 1430
18. Moore H., Summerbell C.D., Greenwood D.C., et al. Improving management of obesity in primary care: cluster randomised trial. BMJ 327 (2003) 1085
19. Nemeth L.S., Feifer C., Stuart G.W., and Ornstein S.M. Implementing change in primary care practices using electronic medical records: a conceptual framework. Implement Sci 3 (2008) 3
20. Feifer C., and Ornstein S.M. Strategies for increasing adherence to clinical guidelines and improving patient outcomes in small primary care practices. Jt Comm J Qual Saf 30 (2004) 432-441
21. Gail M.H., Mark S.D., Carroll R.J., Green S.B., and Pee D. On design considerations and randomization-based inference for community intervention trials. Stat Med 15 (1996) 1069-1092