On enhancers and inhibitors of elastin-derived amyloidogenesis

Nanomedicine

Volumn 4, Issue 1, 2009, Pages 31-46

  Bochicchio, Brigida ^a   Lorusso, Marina ^a   Pepe, Antonietta ^a   Tamburro, Antonio Mario ^a  

^a UNIVERSITY OF BASILICATA   (Italy)

Author keywords

Amyloidogenesis inhibitors; Amyloids; Turbidimetry

Indexed keywords

AMYLOID BETA PROTEIN[25-35]; CONGO RED; ELASTIN; LYSYLLEUCYLVALYLPHENYLALANYLPHENYLALANINE; PENTAPEPTIDE; TAUROCHOLIC ACID; THIOFLAVINE; UNCLASSIFIED DRUG; VALYLPHENYLALANYLGLYCYLLEUCYLGLYCINE; AMYLOID; AMYLOID BETA PROTEIN; AMYLOID BETA PROTEIN (16 20); AMYLOID BETA-PROTEIN (16-20); PEPTIDE; PEPTIDE FRAGMENT;

AMINO ACID SEQUENCE; AMYLOIDOSIS; ARTICLE; ATOMIC FORCE MICROSCOPY; CIRCULAR DICHROISM; DRUG DESIGN; DRUG PROTEIN BINDING; FLUORESCENCE ANALYSIS; PEPTIDE SYNTHESIS; PHARMACOLOGICAL BLOCKING; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN SECONDARY STRUCTURE; TURBIDIMETRY; CHEMISTRY; HUMAN; METABOLISM; TEMPERATURE; TIME; ULTRASTRUCTURE;

AMYLOID; AMYLOID BETA-PROTEIN; AMYLOIDOSIS; ELASTIN; HUMANS; PEPTIDE FRAGMENTS; PEPTIDES; TAUROCHOLIC ACID; TEMPERATURE; TIME FACTORS;

EID: 60249089077     PISSN: 17435889     EISSN: None     Source Type: Journal    
DOI: 10.2217/17435889.4.1.31     Document Type: Article

References (30)

1. Bochicchio B, Pepe A, Flamia R, Lorusso M, Tamburro AM: Investigating the amyloidogenic nanostructured sequences of elastin: sequence encoded by exon 28 of human tropoelastin gene. Biomacromolecules8(11),3478-3486 (2007).
2. Tamburro AM, Pepe A, Bochicchio B, Quaglino D, Ronchetti IP: Supramolecular amyloid-like assembly of the polypeptide sequence coded by exon 30 of human tropoelastin. J. Biol. Chem.280 (4),2682-2690 (2005).
3. Bochicchio B, Pepe A, Tamburro AM: Elastic fibers and amyloid deposition in vascular tissue. Future Neurol.2,523-536 (2007).
4. Ostuni A, Bochicchio B, Armentano MF, Bisaccia F, Tamburro AM: Molecular and supramolecular structural studies on human tropoelastin sequences. Biophys. J.93(10),3640-3651 (2007).
5. Flamia R, Lanza G, Salvi AM, Castle JE, Tamburro AM: Conformational study and hydrogen bonds detection on elastin-related polypeptides using X-ray photoelectron spectroscopy. Biomacromolecules6(3),1299-1309 (2005).
6. Flamia R, Salvi AM, D'Alessio L, Castle JE, Tamburro AM: Transformation of amyloid-like fibers, formed from an elastin-based biopolymer, into a hydrogel: an X-ray photoelectron spectroscopy and atomic force microscopy study. Biomacromolecules8(1),128-138 (2007).
7. Flamia R, Zhdan PA, Martino M, Castle JE, Tamburro AM: AFM study of the elastin-like biopolymer poly (ValGlyGlyValGly). Biomacromolecules5(4),1511-1518 (2004).
8. Del Mercato LL, Pompa PP, Maruccio G et al.: Charge transport and intrinsic fluorescence in amyloidlike fibrils. Proc. Natl Acad. Sci. USA104(46),18019-18024 (2007).
9. Pepe A, Guerra D, Bochicchio B et al.: Dissection of human tropoelastin: supramolecular organization of polypeptide sequences coded by particular exons. Matrix Biol.24(2),96-109 (2005).
10. Tamburro AM, Bochicchio B, Pepe A: Dissection of human tropoelastin: exon- by-exon chemical synthesis and related conformational studies. Biochemistry42(45),13347-13362 (2003).
11. Guantieri V, Tarnburro AM, Gordini DD: Interactions of human and bovine elastins with lipids: their proteolysis by elastase. Connect. Tissue Res. 12(1),79-83 (1983).
12. Getie M, Schmelzer CE, Neubert RH: Characterization of peptides resulting from digestion of human skin elastin with elastase. Proteins61 (3),649-657 (2005).
13. Mattson MP, Cheng B, Davis D et al.: β-amyloid peptides destabilize calcium homeostasis and render human cortical neurons vulnerable to excitotoxicity. J. Neurosci. 12(2),376-389 (1992).
14. Gestwicki JE, Crabtree GR, Graef IA: Harnessing chaperones to generate small-molecule inhibitors of amyloid-β aggregation. Science306 (5697),865-869 (2004).
15. Necula M, Kayed R, Milton S, Glabe CG: Small molecule inhibitors of aggregation indicate that amyloidβ oligomerization and fibrillization pathways are independent and distinct. J. Biol. Chem.282 (14),10311-10324 (2007).
16. D'Ursi AM, Armenante MR, Guerrini R et al.: Solution structure of amyloid-β-peptide (25-35) in different media. J. Med. Chem.47 (17),4231-4238 (2004).
17. Tjernberg LO, Naslund J, Lindqvist F et al.: Arrest of βamyloid fibril formation by a pentapeptide ligand. J. Biol. Chem.271(15),8545-8548 (1996).
18. Luo Y, Smith JV, Paramasivam V et al.: Inhibition of amyloid-β aggregation and caspase-3 activation by the Ginkgo biloba extract EGb761. Proc. Natl Acad. Sci. USA99 (19),12197-12202 (2002).
19. Wu Y, Wu Z, Butko P et al.: Amyloid-β-induced pathological behaviors are suppressed by Ginkgo biloba extract EGb 761 and ginkgolides in transgenic Caenorhabditis elegans. J. Neurosci.2613102-13113 (2006).
20. Nakanishi K: Terpene trilactones from Gingko biloba: from ancient times to the 21st century. Bioorg. Med. Chem.13(17),4987-5000 (2005).
21. van Beek TA: Ginkgolides and bilobatide: their physical, chromatographic and spectroscopic properties. Bioorg. Med. Chem.13 (17),5001-5012 (2005).
22. Bochicchio B, Tamburro AM: Polyproline II structure in proteins: identification by chiroptical spectroscopies, stability, and functions. Chirality14(10),782-792 (2002).
23. Geddes AJ, Parker KD, Atkins ED, Beighton E: "Cross-β" conformation in proteins. J. Mol. Biol.32(2),343-358 (1968).
24. Jimenez JL, Nettleton EJ, Bouchard M et al.: The protofilament structure of insulin amyloid fibrils. Proc. Natl Acad. Sci. USA99 (14),9196-9201 (2002).
25. Eanes ED, Glenner GG: X-ray diffraction studies on amyloid filaments. J. Histochem. Cytochem.16 (11),673-677 (1968).
26. Roccatano D, Colombo G, Fioroni M, Mark AE: Mechanism by which 2,2,2-trifluoroethanol/water mixtures stabilize secondary-structure formation in peptides: a molecular dynamics study. Proc. Natl Acad. Sci. USA99(19),12179-12184 (2002).
27. Koldamova R, Staufenbiel M, Lefterov I: Lack of ABCA1 considerably decreases brain ApoE level and increases amyloid deposition in APP23 mice. J. Biol. Chem.280(52),43224-43235 (2005).
28. Coisne D, Corbi P, Sosner P: Obstructive intramural coronary amyloidosis and papillary muscle rupture. Heart89(2),E8 (2003).
29. Dookstam S, Bohl JRE, Sahraian A, Mahjoor AA: Amyloid deposits in senile vertebral arteries, immunohistological and ultrastructural findings. Pak. J. Biol. Sci.11(14),1852-1855 (2008).
30. Soto C, Kindy MS, Baumann M, Frangione B: Inhibition of Alzheimer's amyloidosis by peptides that prevent β-sheet conformation. Biochem. Biophys. Res. Commun.226 (3),672-680 (1996).