Risk factors for mortality in patients with Acinetobacter baumannii bloodstream infection with genotypic species identification

Journal of Microbiology, Immunology and Infection

Volumn 41, Issue 5, 2008, Pages 397-402

  Chiang, Dung Hung ^a   Wang, Chien Chun ^a   Kuo, Han Yueh ^a   Chen, Hsin Pai ^b   Chen, Te Li ^a,b   Wang, Fu Der ^a   Cho, Wen Long ^b   Liu, Cheng Yi ^a  

^a TAIPEI VETERANS GENERAL HOSPITAL   (Taiwan)

^b NATIONAL YANG MING UNIVERSITY   (Taiwan)

Author keywords

Acinetobacter baumannii; Bacteremia; Mortality; Risk factors; Sequence analysis, DNA

Indexed keywords

AMIKACIN; ANTIBIOTIC AGENT; ANTIINFECTIVE AGENT; CEFEPIME; CEFTRIAXONE; CIPROFLOXACIN; COTRIMOXAZOLE; CREATININE; GENTAMICIN; IMIPENEM; LEVOFLOXACIN; PIPERACILLIN PLUS TAZOBACTAM; SULTAMICILLIN; TIMENTIN; TOBRAMYCIN;

ACINETOBACTER BAUMANNII; ACINETOBACTER INFECTION; ADOLESCENT; ADULT; AGED; ANTIBIOTIC THERAPY; ANTIMICROBIAL THERAPY; ARTICLE; BACTEREMIA; BACTERIUM ISOLATE; BLOODSTREAM INFECTION; CREATININE BLOOD LEVEL; DRUG SENSITIVITY; FEMALE; GENOTYPE; HUMAN; INFECTION RISK; KIDNEY FAILURE; LABORATORY TEST; MAJOR CLINICAL STUDY; MALE; MEDICAL RECORD; MORTALITY; MULTIVARIATE ANALYSIS; NONHUMAN; PREDICTOR VARIABLE; PROGNOSIS; RETROSPECTIVE STUDY; RISK FACTOR; SPECIES IDENTIFICATION; SURVIVAL; TAIWAN;

ACINETOBACTER BAUMANNII; ACINETOBACTER INFECTIONS; ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; BACTEREMIA; CHI-SQUARE DISTRIBUTION; FEMALE; HUMANS; MALE; MICROBIAL SENSITIVITY TESTS; MIDDLE AGED; MULTIVARIATE ANALYSIS; PROGNOSIS; RETROSPECTIVE STUDIES; RISK FACTORS; STATISTICS, NONPARAMETRIC;

EID: 60249087781     PISSN: 16841182     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (20)

1. Chen HP, Chen TL, Lai CH, Fung CP, Wong WW, Yu KW, et al. Predictors of mortality in Acinetobacter baumannii bacteremia. J Microbiol Immunol Infect. 2005;38:127-36.
2. Fagon JY, Chastre J, Domart Y, Trouillet JL, Gibert C. Mortality due to ventilator-associated pneumonia or colonization with Pseudomonas or Acinetobacter species: assessment by quantitative culture of samples obtained by a protected specimen brush. Clin Infect Dis. 1996;23:538-42.
3. Beck-Sagué CM, Jarvis WR, Brook JH, Culver DH, Potts A, Gay E, et al. Epidemic bacteremia due to Acinetobacter baumannii in five intensive care units. Am J Epidemiol. 1990;132:723-33.
4. Villers D, Espaze E, Coste-Burel M, Giauffret F, Ninin E, Nicolas F, et al. Nosocomial Acinetobacter baumannii infections: microbiological and clinical epidemiology. Ann Intern Med. 1998;129:182-9.
5. Lortholary O, Fagon JY, Hoi AB, Slama MA, Pierre J, Giral P, et al. Nosocomial acquisition of multiresistant Acinetobacter baumanni: risk factors and prognosis. Clin Infect Dis. 1995;20:790-6.
6. Gombac F, Riccio ML, Rossolini GM, Lagatolla C, Tonin E, Monti-Bragadin C, et al. Molecular characterization of integrons in epidemiologically unrelated clinical isolates of Acinetobacter baumannii from Italian hospitals reveals a limited diversity of gene cassette arrays. Antimicrob Agents Chemother. 2002;46:3665-8.
7. Vila J, Navia M, Ruiz J, Casals C. Cloning and nucleotide sequence analysis of a gene encoding an OXA-derived beta-lactamase in Acinetobacter baumannii. Antimicrob Agents Chemother. 1997;41:2757-9.
8. Nemec A, Dolzani L, Brisse S, van den Broek P, Dijk-shoorn L. Diversity of aminoglycoside-resistance genes and their association with class 1 integrons among strains of pan-European Acinetobacter baumannii clones. J Med Microbiol. 2004;53(Pt 12): 1233-40.
9. Ploy MC, Denis F, Courvalin P, Lambert T. Molecular characterization of integrons in Acinetobacter baumannii: description of a hybrid class 2 integron. Antimicrob Agents Chemother. 2000;44:2684-8.
10. Kraniotaki E, Manganelli R, Platsouka E, Grossato A, Paniara O, Palù G. Molecular investigation of an outbreak of multidrug-resistant Acinetobacter baumannii, with characterisation of class 1 integrons. Int J Antimicrob Agents. 2006;28:193-9.
11. Kuo LC, Yu CJ, Lee LN, Wang JL, Wang HC, Hsueh PR, et al. Clinical features of pandrug-resistant Acinetobacter baumannii bacteremia at a university hospital in Taiwan. J Formos Med Assoc. 2003;102:601-6.
12. Chen CH, Lin LC, Chang YJ, Huang CC, Liu CE, Young TG. Analysis of prognostic factors in 95 patients with Acinetobacter baumannii bacteremia. Infection. 2003 ;31: 331-5.
13. Choi JY, Park YS, Kim CO, Park YS, Yoon HJ, Shin SY, et al. Mortality risk factors of Acinetobacter baumannii bacteraemia. Intern Med J. 2005;35:599-603.
14. Seifert H, Strate A, Pulverer G. Nosocomial bacteremia due to Acinetobacter baumannii. Clinical features, epidemiology, and predictors of mortality. Medicine (Baltimore). 1995;74:340-9.
15. Chen TL, Siu LK, Wu RC, Shaio MF, Huang LY, Fung CP, et al. Comparison of one-tube multiplex PCR, automated ribotyping and intergenic spacer (ITS) sequencing for rapid identification of Acinetobacter baumannii. Clin Microbiol Infect. 2007;13:801-6.
16. Performance standards for antimicrobial susceptibility testing. CLSI document M100-S15. Villanova: Clinical Laboratory Standards Institute; 2005.
17. Valero C, García Palomo JD, Matorras P, Fernández-Mazarrasa C, González Fernández C, Fariñas MC. Acinetobacter bacteraemia in a teaching hospital, 1989-1998. Eur J Intern Med. 2001;12:425-9.
18. Chen CH, Lin LC, Hwang KL. Nosocomial Acinetobacter baumannii bacteremia: comparison of the clinical manifestations of multiresistant strain and non-multiresistant strain infections. Changhua J Med. 2002;7:86-92.
19. Chen TL, Chuang CL, Siu LK, Fung CP, Cho WL. Genomic species identification is important to delineate the pathological characteristics of Acinetobacter in tunnelled, cuffed haemodialysis catheter-related bacteraemia. Nephrol Dial Transplant. 2007;22:936-8.
20. Bressler AM, Kaye KS, LiPuma JJ, Alexander BD, Moore CM, Reller LB, et al. Risk factors for Burkholderia cepacia complex bacteremia among intensive care unit patients without cystic fibrosis: a case-control study. Infect Control Hosp Epidemiol. 2007;28:951-8.