Stereoselective synthesis of 2,3,7-trimethylcyclooctanone and related compounds and determination of their relative and absolute contigurations by the MαNP acid method

Chirality

Volumn 20, Issue 9, 2008, Pages 1053-1065

  Naito, Junpei ^a   Kuwahara, Shunsuke ^a   Watanabe, Masataka ^a   Decatur, John ^b   Bos, Pieter H ^c   Van Summeren, Ruben P ^c   Ter Horst, Bjorn ^c   Feringa, Ben L ^c   Minnaard, Adriaan J ^c   Harada, Nobuyuki ^a,b  

^a TOHOKU UNIVERSITY   (Japan)

^b Och Spine at New York Presbyterian Hospitals   (United States)

^c UNIVERSITY OF GRONINGEN   (Netherlands)

Author keywords

2,3,7 trimethylcyclooctanol; 2,3,7 trimethylcyclooctanone; 2 methoxy 2 (1 naphthyl)propionic acid; 1H NMR anisotropy; Absolute configuration; Asymmetric conjugate addition; Chiral phosphoramidite; HPLC separation on silica gel; HSQC TOCSY; M NP acid; Stereochemistry

Indexed keywords

2 METHOXY 2 (1 NAPHTHYL)PROPIONIC ACID; 2,3,7 TRIMETHYLCYCLOOCTANONE; ALCOHOL; CYCLOOCTANE DERIVATIVE; ESTER DERIVATIVE; PROPIONIC ACID DERIVATIVE; UNCLASSIFIED DRUG;

ADDITION REACTION; ANISOTROPY; CARBON NUCLEAR MAGNETIC RESONANCE; CATALYSIS; CHEMICAL STRUCTURE; CONFERENCE PAPER; ESTERIFICATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; METHYLATION; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; SEPARATION TECHNIQUE; STEREOCHEMISTRY; STEREOISOMERISM; SYNTHESIS;

EID: 60149111405     PISSN: 08990042     EISSN: 1520636X     Source Type: Journal    
DOI: 10.1002/chir.20637     Document Type: Conference Paper

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