메뉴 건너뛰기




Volumn 16, Issue 2, 2009, Pages 106-113

Sex hormones and modulation of immunity against leishmaniasis

Author keywords

Immune responses; Leishmaniasis; Sex associated hormones

Indexed keywords

ANDROGEN; ESTROGEN; GESTAGEN; SEX HORMONE;

EID: 60149109937     PISSN: 10217401     EISSN: None     Source Type: Journal    
DOI: 10.1159/000180265     Document Type: Review
Times cited : (66)

References (84)
  • 1
    • 3042555141 scopus 로고    scopus 로고
    • Leishmaniasis: Current situation and new perspectives
    • Desjeux P: Leishmaniasis: current situation and new perspectives. Comp Immunol Microbiol Infect Dis 2004;27:305-318.
    • (2004) Comp Immunol Microbiol Infect Dis , vol.27 , pp. 305-318
    • Desjeux, P.1
  • 2
    • 60149101609 scopus 로고    scopus 로고
    • WHO programmes and Projects
    • WHO programmes and Projects. http://www.who.int/leishmaniasis/en/.
  • 3
    • 0003732386 scopus 로고    scopus 로고
    • The World Health Report. Geneva
    • World Health Organization
    • World Health Organization: The World Health Report. Geneva, World Health Organization, 2002, pp 192-197.
    • (2002) World Health Organization , pp. 192-197
  • 4
    • 0026533657 scopus 로고
    • The interaction of Leishmania species with macrophages
    • Alexander J, Russell D: The interaction of Leishmania species with macrophages. Adv Parasitol 1992;31:175-254.
    • (1992) Adv Parasitol , vol.31 , pp. 175-254
    • Alexander, J.1    Russell, D.2
  • 5
    • 0027248719 scopus 로고
    • Langerhans cells transport Leishmania major from infected skin to the draining lymph node for presentation to antigen-specific T cells
    • Moll H, Fuchs H, Blank C, Rollinghoff M: Langerhans cells transport Leishmania major from infected skin to the draining lymph node for presentation to antigen-specific T cells. Eur J Immunol 1993;23:1595-1601.
    • (1993) Eur J Immunol , vol.23 , pp. 1595-1601
    • Moll, H.1    Fuchs, H.2    Blank, C.3    Rollinghoff, M.4
  • 7
    • 0032883457 scopus 로고    scopus 로고
    • Leishmania species: Models of intracellular parasitism
    • Alexander J, Satoskar AR, Russell DG: Leishmania species: models of intracellular parasitism. J Cell Sci 1999;112:2993-3002.
    • (1999) J Cell Sci , vol.112 , pp. 2993-3002
    • Alexander, J.1    Satoskar, A.R.2    Russell, D.G.3
  • 8
    • 19344362323 scopus 로고    scopus 로고
    • T helper (h)1/Th2 and Leishmania: Paradox rather than paradigm
    • Alexander J, Bryson K: T helper (h)1/Th2 and Leishmania: paradox rather than paradigm. Immunol Lett 2005;99:17-23.
    • (2005) Immunol Lett , vol.99 , pp. 17-23
    • Alexander, J.1    Bryson, K.2
  • 9
    • 0037313578 scopus 로고    scopus 로고
    • Interleukin-12 and the regulation of innate resistance and adaptive immunity
    • Trinchieri G: Interleukin-12 and the regulation of innate resistance and adaptive immunity. Nat Rev Immunol 2003;3:133-146.
    • (2003) Nat Rev Immunol , vol.3 , pp. 133-146
    • Trinchieri, G.1
  • 10
    • 0041488744 scopus 로고    scopus 로고
    • Interleukin 1alpha promotes Th1 differentiation and inhibits disease progression in Leishmania major-susceptible BALB/c mice
    • von Stebut E, Ehrchen JM, Belkaid Y, Kostka SL, Molle K, Knop J, Sunderkotter C, Udey MC: Interleukin 1alpha promotes Th1 differentiation and inhibits disease progression in Leishmania major-susceptible BALB/c mice. J Exp Med 2003;198:191-199.
    • (2003) J Exp Med , vol.198 , pp. 191-199
    • von Stebut, E.1    Ehrchen, J.M.2    Belkaid, Y.3    Kostka, S.L.4    Molle, K.5    Knop, J.6    Sunderkotter, C.7    Udey, M.C.8
  • 14
    • 0032476741 scopus 로고    scopus 로고
    • Interferon gamma derived from CD4(+) T cells is sufficient to mediate T helper cell type 1 development
    • Wakil AE, Wang ZE, Ryan JC, Fowell DJ, Locksley RM: Interferon gamma derived from CD4(+) T cells is sufficient to mediate T helper cell type 1 development. J Exp Med 1998;188:1651-1656.
    • (1998) J Exp Med , vol.188 , pp. 1651-1656
    • Wakil, A.E.1    Wang, Z.E.2    Ryan, J.C.3    Fowell, D.J.4    Locksley, R.M.5
  • 15
    • 0033153483 scopus 로고    scopus 로고
    • Mice lacking NK cells develop an efficient Th1 response and control cutaneous Leishmania major infection
    • Satoskar AR, Stamm LM, Zhang X, Okano M, David JR, Terhorst C, Wang B: Mice lacking NK cells develop an efficient Th1 response and control cutaneous Leishmania major infection. J Immunol 1999;162:6747-6754.
    • (1999) J Immunol , vol.162 , pp. 6747-6754
    • Satoskar, A.R.1    Stamm, L.M.2    Zhang, X.3    Okano, M.4    David, J.R.5    Terhorst, C.6    Wang, B.7
  • 16
    • 0036343130 scopus 로고    scopus 로고
    • Parasite adaptive mechanisms in infection by Leishmania
    • Cunningham AC: Parasite adaptive mechanisms in infection by Leishmania. Exp Mol Pathol 2002;72:132-141.
    • (2002) Exp Mol Pathol , vol.72 , pp. 132-141
    • Cunningham, A.C.1
  • 17
    • 0032973137 scopus 로고    scopus 로고
    • Immune effector mechanism in parasitic infections
    • Liew FY, Xu D, Chan WL: Immune effector mechanism in parasitic infections. Immunol Lett 1999;65:101-104.
    • (1999) Immunol Lett , vol.65 , pp. 101-104
    • Liew, F.Y.1    Xu, D.2    Chan, W.L.3
  • 18
    • 0025326712 scopus 로고
    • Tumor necrosis factor alpha in combination with interferon gamma, but not with interleukin-4, activates murine macrophages for elimination of Leishmania major amastigotes
    • Bogdan C, Moll H, Solbach W, Rollinghoff M: Tumor necrosis factor alpha in combination with interferon gamma, but not with interleukin-4, activates murine macrophages for elimination of Leishmania major amastigotes. Eur J Immunol 1990;20:1131-1135.
    • (1990) Eur J Immunol , vol.20 , pp. 1131-1135
    • Bogdan, C.1    Moll, H.2    Solbach, W.3    Rollinghoff, M.4
  • 19
    • 0032520619 scopus 로고    scopus 로고
    • Underproduction of interleukin-12 in susceptible mice during progressive leishmaniasis is due to decreased CD40 activity
    • Heinzel FP, Rerko RM, Hujer AM: Underproduction of interleukin-12 in susceptible mice during progressive leishmaniasis is due to decreased CD40 activity. Cell Immunol 1998;184:124-142.
    • (1998) Cell Immunol , vol.184 , pp. 124-142
    • Heinzel, F.P.1    Rerko, R.M.2    Hujer, A.M.3
  • 20
    • 0029925517 scopus 로고    scopus 로고
    • Soong L, Xu JC, Grewal IS, Kima P, Sun J, Longley BJ Jr, Ruddle NH, McMahon-Pratt D, Flavell RA: Disruption of CD40-CD40 ligand interactions results in a enhanced susceptibility to Leishmania amazonensis infection. Immunity 1996;4:263-273.
    • Soong L, Xu JC, Grewal IS, Kima P, Sun J, Longley BJ Jr, Ruddle NH, McMahon-Pratt D, Flavell RA: Disruption of CD40-CD40 ligand interactions results in a enhanced susceptibility to Leishmania amazonensis infection. Immunity 1996;4:263-273.
  • 22
    • 0029933509 scopus 로고    scopus 로고
    • Protective role of CD40 in Leishmania major infection at two distinct phases of cell-mediated immunity
    • Kamanaka M, Yu P, Yasui T, Yoshida K, Kawabe T, Horii T, Kishimoto T, Kikutani H: Protective role of CD40 in Leishmania major infection at two distinct phases of cell-mediated immunity. Immunity 1996;4:275-281.
    • (1996) Immunity , vol.4 , pp. 275-281
    • Kamanaka, M.1    Yu, P.2    Yasui, T.3    Yoshida, K.4    Kawabe, T.5    Horii, T.6    Kishimoto, T.7    Kikutani, H.8
  • 23
    • 0030023112 scopus 로고    scopus 로고
    • Susceptibility to Leishmania major infection in interleukin-4-deficient mice
    • Noben-Trauth N, Kropf P, Muller I: Susceptibility to Leishmania major infection in interleukin-4-deficient mice. Science 1996;271:987-990.
    • (1996) Science , vol.271 , pp. 987-990
    • Noben-Trauth, N.1    Kropf, P.2    Muller, I.3
  • 24
    • 0034106507 scopus 로고    scopus 로고
    • Interleukin-4 receptor alpha-deficient BALB/c mice show an unimpaired T helper 2 polarization in response to Leishmania major infection
    • Mohrs M, Holscher C, Brombacher F: Interleukin-4 receptor alpha-deficient BALB/c mice show an unimpaired T helper 2 polarization in response to Leishmania major infection. Infect Immun 2000;68:1773-1780.
    • (2000) Infect Immun , vol.68 , pp. 1773-1780
    • Mohrs, M.1    Holscher, C.2    Brombacher, F.3
  • 26
    • 4844231880 scopus 로고    scopus 로고
    • Re-examination of the immunosuppressive mechanisms mediating non-cure of Leishmania infection in mice
    • Sacks D, Anderson C: Re-examination of the immunosuppressive mechanisms mediating non-cure of Leishmania infection in mice. Immunol Rev 2004;201:225-228.
    • (2004) Immunol Rev , vol.201 , pp. 225-228
    • Sacks, D.1    Anderson, C.2
  • 27
    • 0033788429 scopus 로고    scopus 로고
    • Endogenous IL-4 is necessary for effective drug therapy against visceral leishmaniasis
    • Alexander J, Carter KC, Al-Fasi N, Satoskar A, Brombrocher F: Endogenous IL-4 is necessary for effective drug therapy against visceral leishmaniasis. Eur J Immunol 2000;30:2935-2943.
    • (2000) Eur J Immunol , vol.30 , pp. 2935-2943
    • Alexander, J.1    Carter, K.C.2    Al-Fasi, N.3    Satoskar, A.4    Brombrocher, F.5
  • 28
    • 0042745627 scopus 로고    scopus 로고
    • Both interleukin-4 (IL-4) and IL-4 receptor alpha signaling contribute to the development of hepatic granulomas with optimal antileishmanial activity
    • Stager S, Alexander J, Carter KC, Brombacher F, Kay PM: Both interleukin-4 (IL-4) and IL-4 receptor alpha signaling contribute to the development of hepatic granulomas with optimal antileishmanial activity. Infect Immun 2003;71:4804-4807.
    • (2003) Infect Immun , vol.71 , pp. 4804-4807
    • Stager, S.1    Alexander, J.2    Carter, K.C.3    Brombacher, F.4    Kay, P.M.5
  • 30
    • 0026500979 scopus 로고
    • IL-4 induces a Th2 response in Leishmania major-infected mice
    • Chatelain R, Varkila K, Coffman RL: IL-4 induces a Th2 response in Leishmania major-infected mice. J Immunol 1992;148:1182-1187.
    • (1992) J Immunol , vol.148 , pp. 1182-1187
    • Chatelain, R.1    Varkila, K.2    Coffman, R.L.3
  • 32
    • 0035863867 scopus 로고    scopus 로고
    • The role of IL-10 in promoting disease progression in leishmaniasis
    • Kane MM, Mosser DM: The role of IL-10 in promoting disease progression in leishmaniasis. J Immunol 2001;166:1141-1147.
    • (2001) J Immunol , vol.166 , pp. 1141-1147
    • Kane, M.M.1    Mosser, D.M.2
  • 34
    • 0033555789 scopus 로고    scopus 로고
    • Anti-TGF-beta treatment promotes rapid healing of Leishmania major infection in mice by enhancing in vivo nitric oxide production
    • Li J, Hunter CA, Farrell JP: Anti-TGF-beta treatment promotes rapid healing of Leishmania major infection in mice by enhancing in vivo nitric oxide production. J Immunol 1999;162:974-979.
    • (1999) J Immunol , vol.162 , pp. 974-979
    • Li, J.1    Hunter, C.A.2    Farrell, J.P.3
  • 35
    • 0034689062 scopus 로고    scopus 로고
    • Internalization of Leishmania mexicana complex amastigotes via the Fc receptor is required to sustain infection in murine cutaneous leishmanisis
    • Kima PE, Constant SL, Hannum L, Colmenares M, Lee KS, Haberman AM, Shlomchik MJ, McMahon-Pratt D: Internalization of Leishmania mexicana complex amastigotes via the Fc receptor is required to sustain infection in murine cutaneous leishmanisis. J Exp Med 2000;191:1063-1067.
    • (2000) J Exp Med , vol.191 , pp. 1063-1067
    • Kima, P.E.1    Constant, S.L.2    Hannum, L.3    Colmenares, M.4    Lee, K.S.5    Haberman, A.M.6    Shlomchik, M.J.7    McMahon-Pratt, D.8
  • 36
    • 0015165636 scopus 로고
    • Immunological phenomena in leprosy and related diseases
    • Turk JL, Bryceson ADM: Immunological phenomena in leprosy and related diseases. Adv Immunol 1971;13:209-266.
    • (1971) Adv Immunol , vol.13 , pp. 209-266
    • Turk, J.L.1    Bryceson, A.D.M.2
  • 40
    • 0020522331 scopus 로고
    • Specific estrogen binding sites in human lymphoid cells and thymic cells
    • Danel L, Souweine G, Monier JC, Saez S: Specific estrogen binding sites in human lymphoid cells and thymic cells. J Steroid Biochem 1983;18:559-563.
    • (1983) J Steroid Biochem , vol.18 , pp. 559-563
    • Danel, L.1    Souweine, G.2    Monier, J.C.3    Saez, S.4
  • 41
    • 49249122123 scopus 로고    scopus 로고
    • Toll-like receptor-4-mediated macrophage activation is differentially regulated by progesterone via the glucocorticoid and progesterone receptors
    • Jones LA, Anthony JP, Henrique FL, Lyons RE, Nickdel MB, Carter KC, Alexander J, Roberts CW: Toll-like receptor-4-mediated macrophage activation is differentially regulated by progesterone via the glucocorticoid and progesterone receptors. Immunology 2008;125:59-69.
    • (2008) Immunology , vol.125 , pp. 59-69
    • Jones, L.A.1    Anthony, J.P.2    Henrique, F.L.3    Lyons, R.E.4    Nickdel, M.B.5    Carter, K.C.6    Alexander, J.7    Roberts, C.W.8
  • 42
    • 0034284490 scopus 로고    scopus 로고
    • Role of hormone-controlled Th1-and Th2-type cytokines in successful pregnancy
    • Piccinni MP, Scaletti C, Maggi E, Romagnani S: Role of hormone-controlled Th1-and Th2-type cytokines in successful pregnancy. J Neuroimmunol 2000;109:30-33.
    • (2000) J Neuroimmunol , vol.109 , pp. 30-33
    • Piccinni, M.P.1    Scaletti, C.2    Maggi, E.3    Romagnani, S.4
  • 43
    • 0023874125 scopus 로고
    • Effect of sex hormones on NK and ADCC activity of mice
    • Hou J, Zheng WF: Effect of sex hormones on NK and ADCC activity of mice. Int J Immunopharmacol 1988;10:15-22.
    • (1988) Int J Immunopharmacol , vol.10 , pp. 15-22
    • Hou, J.1    Zheng, W.F.2
  • 44
    • 0022261145 scopus 로고
    • Mechanisms of diminished natural killer cell activity in pregnant women and neonates
    • Baley JE, Schacter BZ: Mechanisms of diminished natural killer cell activity in pregnant women and neonates. J Immunol 1985;134:3042-3048.
    • (1985) J Immunol , vol.134 , pp. 3042-3048
    • Baley, J.E.1    Schacter, B.Z.2
  • 45
    • 0021713291 scopus 로고
    • Changes in NK cell activity during the estrous cycle and pregnancy in mice
    • Furukawa K, Itoh K, Okamura K, Kumagai K, Suzuki M: Changes in NK cell activity during the estrous cycle and pregnancy in mice. J Reprod Immunol 1984;6:353-363.
    • (1984) J Reprod Immunol , vol.6 , pp. 353-363
    • Furukawa, K.1    Itoh, K.2    Okamura, K.3    Kumagai, K.4    Suzuki, M.5
  • 46
    • 0021275448 scopus 로고
    • Studies of natural killer cells in pregnancy. 2. The immunoregulatory effect of pregnancy substances
    • Toder V, Nebel L, Elrad H, Blank M, Durdana A, Gleicher N: Studies of natural killer cells in pregnancy. 2. The immunoregulatory effect of pregnancy substances. J Clin Lab Immunol 1984;14:129-133.
    • (1984) J Clin Lab Immunol , vol.14 , pp. 129-133
    • Toder, V.1    Nebel, L.2    Elrad, H.3    Blank, M.4    Durdana, A.5    Gleicher, N.6
  • 48
    • 0029866697 scopus 로고    scopus 로고
    • Progesterone inhibits inducible nitric oxide synthase gene expression and nitric oxide production in murine macrophages
    • Miller L, Alley EW, Murphy WJ, Russell SW, Hunt JS: Progesterone inhibits inducible nitric oxide synthase gene expression and nitric oxide production in murine macrophages. J Leukoc Biol 1996;59:442-450.
    • (1996) J Leukoc Biol , vol.59 , pp. 442-450
    • Miller, L.1    Alley, E.W.2    Murphy, W.J.3    Russell, S.W.4    Hunt, J.S.5
  • 49
    • 0032525051 scopus 로고    scopus 로고
    • Regulation of TNF-alpha production in activated mouse macrophages by progesterone
    • Miller L, Hunt JS: Regulation of TNF-alpha production in activated mouse macrophages by progesterone. J Immunol 1998;160:5098-5104.
    • (1998) J Immunol , vol.160 , pp. 5098-5104
    • Miller, L.1    Hunt, J.S.2
  • 50
    • 0036781052 scopus 로고    scopus 로고
    • NF-kappaB regulation in the immune system
    • Li Q, Verma IM: NF-kappaB regulation in the immune system. Nat Rev Immunol 2002;2:725-734.
    • (2002) Nat Rev Immunol , vol.2 , pp. 725-734
    • Li, Q.1    Verma, I.M.2
  • 53
    • 0027193481 scopus 로고
    • Enhancing effect of 17 beta-estradiol on human NK cell activity
    • Sorachi K, Kumagai S, Sugita M, Yodoi J, Imura H: Enhancing effect of 17 beta-estradiol on human NK cell activity. Immunol Lett 1993;36:31-35.
    • (1993) Immunol Lett , vol.36 , pp. 31-35
    • Sorachi, K.1    Kumagai, S.2    Sugita, M.3    Yodoi, J.4    Imura, H.5
  • 55
    • 0027937803 scopus 로고
    • Estrogen induces suppression of natural killer cell cytotoxicity and augmentation of polyclonal B cell activation
    • Nilsson N, Carlsten H: Estrogen induces suppression of natural killer cell cytotoxicity and augmentation of polyclonal B cell activation. Cell Immunol 1994;158:131-139.
    • (1994) Cell Immunol , vol.158 , pp. 131-139
    • Nilsson, N.1    Carlsten, H.2
  • 56
    • 0029974267 scopus 로고    scopus 로고
    • Sex steroid hormones and macrophage function
    • Miller L, Hunt JS: Sex steroid hormones and macrophage function. Life Sci 1996;59:1-14.
    • (1996) Life Sci , vol.59 , pp. 1-14
    • Miller, L.1    Hunt, J.S.2
  • 57
    • 0029145465 scopus 로고
    • In vivo modulation of murine serum tumour necrosis factor and interleukin-6 levels during endotoxemia by oestrogen agonists and antagonists
    • Zuckerman SH, Bryan-Poole N, Evans GF, Short L, Glasebrook AL: In vivo modulation of murine serum tumour necrosis factor and interleukin-6 levels during endotoxemia by oestrogen agonists and antagonists. Immunology 1995;86:18-24.
    • (1995) Immunology , vol.86 , pp. 18-24
    • Zuckerman, S.H.1    Bryan-Poole, N.2    Evans, G.F.3    Short, L.4    Glasebrook, A.L.5
  • 58
    • 0026001659 scopus 로고
    • Estrogen regulates the IFN-gamma promoter
    • Fox HS, Bond BL, Parslow TG: Estrogen regulates the IFN-gamma promoter. J Immunol 1991;146:4362-4367.
    • (1991) J Immunol , vol.146 , pp. 4362-4367
    • Fox, H.S.1    Bond, B.L.2    Parslow, T.G.3
  • 59
    • 0344838658 scopus 로고    scopus 로고
    • Estradiol enhances primary antigen-specific CD4 T cell responses and Th1 development in vivo. Essential role of estrogen receptor alpha expression in hematopoietic cells
    • Maret A, Coudert JD, Garidou L, Foucras G, Gourdy P, Krust A, Dupont S, Chambon P, Druet P, Bayard F, Guery JC: Estradiol enhances primary antigen-specific CD4 T cell responses and Th1 development in vivo. Essential role of estrogen receptor alpha expression in hematopoietic cells. Eur J Immunol 2003;33:512-521.
    • (2003) Eur J Immunol , vol.33 , pp. 512-521
    • Maret, A.1    Coudert, J.D.2    Garidou, L.3    Foucras, G.4    Gourdy, P.5    Krust, A.6    Dupont, S.7    Chambon, P.8    Druet, P.9    Bayard, F.10    Guery, J.C.11
  • 61
    • 0034947253 scopus 로고    scopus 로고
    • Sex-associated hormones and immunity to protozoan parasites
    • Roberts CW, Walker W, Alexander J: Sex-associated hormones and immunity to protozoan parasites. Clin Microbiol Rev 2001;14:476-488.
    • (2001) Clin Microbiol Rev , vol.14 , pp. 476-488
    • Roberts, C.W.1    Walker, W.2    Alexander, J.3
  • 62
    • 33846601437 scopus 로고    scopus 로고
    • Sex-associated susceptibility in humans with chiclero's ulcer: Resistance in females is associated with increased serum-levels of GM-CSF
    • Lezama-Davila CM, Oghumu S, Satoskar AR, Isaac-Marquez AP: Sex-associated susceptibility in humans with chiclero's ulcer: resistance in females is associated with increased serum-levels of GM-CSF. Scand J Immunol 2007;65:210-211.
    • (2007) Scand J Immunol , vol.65 , pp. 210-211
    • Lezama-Davila, C.M.1    Oghumu, S.2    Satoskar, A.R.3    Isaac-Marquez, A.P.4
  • 64
    • 34547138923 scopus 로고    scopus 로고
    • Leishmania panamensis transmission in the domestic environment: The results of a prospective epidemiological survey in Santander, Columbia
    • Munoz G, Davies CR: Leishmania panamensis transmission in the domestic environment: the results of a prospective epidemiological survey in Santander, Columbia. Biomedica 2006;26(suppl 1):131-144.
    • (2006) Biomedica , vol.26 , Issue.SUPPL. 1 , pp. 131-144
    • Munoz, G.1    Davies, C.R.2
  • 69
    • 0023891323 scopus 로고
    • Sex differences and cross-immunity in DBA/2 mice infected with L. mexicana and L. major
    • Alexander J: Sex differences and cross-immunity in DBA/2 mice infected with L. mexicana and L. major. Parasitology 1988;96:297-302.
    • (1988) Parasitology , vol.96 , pp. 297-302
    • Alexander, J.1
  • 70
    • 0028957830 scopus 로고
    • Sex-determined susceptibility and differential IFN-gamma and TNF-alpha mRNA expression in DBA/2 mice infected with Leishmania mexicana
    • Satoskar A, Alexander J: Sex-determined susceptibility and differential IFN-gamma and TNF-alpha mRNA expression in DBA/2 mice infected with Leishmania mexicana. Immunology 1995;84:1-4.
    • (1995) Immunology , vol.84 , pp. 1-4
    • Satoskar, A.1    Alexander, J.2
  • 71
    • 0031901588 scopus 로고    scopus 로고
    • Sex-determined resistance against Leishmania mexicana is associated with the preferential induction of a Th1-like response and IFN-gamma production by female but not male DBA/2 mice
    • Satoskar A, Al-Quassi HH, Alexander J: Sex-determined resistance against Leishmania mexicana is associated with the preferential induction of a Th1-like response and IFN-gamma production by female but not male DBA/2 mice. Immunol Cell Biol 1998;76:159-166.
    • (1998) Immunol Cell Biol , vol.76 , pp. 159-166
    • Satoskar, A.1    Al-Quassi, H.H.2    Alexander, J.3
  • 72
    • 0019274364 scopus 로고
    • Effect of sex hormones on the response of mice to infection with Toxoplasma godii
    • Kittas C, Henry L: Effect of sex hormones on the response of mice to infection with Toxoplasma godii. Br J Exp Pathol 1980;61:590-600.
    • (1980) Br J Exp Pathol , vol.61 , pp. 590-600
    • Kittas, C.1    Henry, L.2
  • 73
    • 0027216898 scopus 로고
    • Natural killer cells participate in the early defense against Leishmania major infection in mice
    • Laskay T, Rollinghoff M, Solbach W: Natural killer cells participate in the early defense against Leishmania major infection in mice. Eur J Immunol 1993;23:2237-2241.
    • (1993) Eur J Immunol , vol.23 , pp. 2237-2241
    • Laskay, T.1    Rollinghoff, M.2    Solbach, W.3
  • 74
    • 34548040748 scopus 로고    scopus 로고
    • 17beta-estradiol increases Leishmania mexicana killing in macrophages from DBA/2 mice by enhancing production of nitric oxide but not pro-inflammatory cytokines
    • Lezama-Davila CM, Isaac-Marquez AP, Barbi J, Oghumu S, Satoskar AR: 17beta-estradiol increases Leishmania mexicana killing in macrophages from DBA/2 mice by enhancing production of nitric oxide but not pro-inflammatory cytokines. Am J Trop Med Hyg 2007;76:1125-1127.
    • (2007) Am J Trop Med Hyg , vol.76 , pp. 1125-1127
    • Lezama-Davila, C.M.1    Isaac-Marquez, A.P.2    Barbi, J.3    Oghumu, S.4    Satoskar, A.R.5
  • 75
    • 49649083754 scopus 로고    scopus 로고
    • Role of phosphatidylinositol-3-kinase-gamma (PI3Kgamma)-mediated pathway in 17beta-estradiol-induced killing of L. mexicana in macrophages from C57BL/6 mice
    • Lezama-Davila CM, Isaac-Marquez AP, Barbi J, Cummings HE, Lu B, Satoskar AR: Role of phosphatidylinositol-3-kinase-gamma (PI3Kgamma)-mediated pathway in 17beta-estradiol-induced killing of L. mexicana in macrophages from C57BL/6 mice. Immunol Cell Biol 2008;86:539-543.
    • (2008) Immunol Cell Biol , vol.86 , pp. 539-543
    • Lezama-Davila, C.M.1    Isaac-Marquez, A.P.2    Barbi, J.3    Cummings, H.E.4    Lu, B.5    Satoskar, A.R.6
  • 76
    • 0030045393 scopus 로고    scopus 로고
    • Pregnancy impairs resistance of C57BL/6 mice to Leishmania major infection and causes decreased antigen-specific IFN-gamma response and increased production of T helper 2 cytokines
    • Krishnan L, Guilbert LJ, Russell AS, Wegmann TG, Mosmann TR, Belosevic M: Pregnancy impairs resistance of C57BL/6 mice to Leishmania major infection and causes decreased antigen-specific IFN-gamma response and increased production of T helper 2 cytokines. J Immunol 1996;156:644-652.
    • (1996) J Immunol , vol.156 , pp. 644-652
    • Krishnan, L.1    Guilbert, L.J.2    Russell, A.S.3    Wegmann, T.G.4    Mosmann, T.R.5    Belosevic, M.6
  • 77
    • 8844236123 scopus 로고    scopus 로고
    • Interleukin-4 (IL-4) and interferon gamma (IFN-gamma) in pregnant C57BL/6 mice infected with L. major at different gestational periods
    • Arinola OG, Louis J, Tacchini-Cottier F, Aseffa A, Salimonu LS: Interleukin-4 (IL-4) and interferon gamma (IFN-gamma) in pregnant C57BL/6 mice infected with L. major at different gestational periods. West Afr J Med 2004;23:202-207.
    • (2004) West Afr J Med , vol.23 , pp. 202-207
    • Arinola, O.G.1    Louis, J.2    Tacchini-Cottier, F.3    Aseffa, A.4    Salimonu, L.S.5
  • 79
    • 45949100431 scopus 로고    scopus 로고
    • Pregnancy enhances the innate immune response in experimental cutaneous leishmaniasis through hormonemodulated nitric oxide production
    • Osorio Y, Bonilla DL, Peniche AG, Melby PC, Travi BL: Pregnancy enhances the innate immune response in experimental cutaneous leishmaniasis through hormonemodulated nitric oxide production. J Leukoc Biol 2008;83:1413-1422.
    • (2008) J Leukoc Biol , vol.83 , pp. 1413-1422
    • Osorio, Y.1    Bonilla, D.L.2    Peniche, A.G.3    Melby, P.C.4    Travi, B.L.5
  • 80
    • 0036117769 scopus 로고    scopus 로고
    • Gender is a major determinant of the clinical evolution and immune response in hamsters infected with Leishmanai spp
    • Travi BL, Osorio Y, Melby PC, Chandrasekar B, Arteaga L, Saravia NG: Gender is a major determinant of the clinical evolution and immune response in hamsters infected with Leishmanai spp. Infect Immun 2002;70:2288-2296.
    • (2002) Infect Immun , vol.70 , pp. 2288-2296
    • Travi, B.L.1    Osorio, Y.2    Melby, P.C.3    Chandrasekar, B.4    Arteaga, L.5    Saravia, N.G.6
  • 81
    • 0025487820 scopus 로고
    • Sex-influenced population kinetics of Leishmania donovani in hamsters
    • Anuradha, Pal R, Katiyar JC: Sex-influenced population kinetics of Leishmania donovani in hamsters. Indian J Exp Biol 1990;28:876-879.
    • (1990) Indian J Exp Biol , vol.28 , pp. 876-879
    • Anuradha1    Pal, R.2    Katiyar, J.C.3
  • 84
    • 21344472797 scopus 로고    scopus 로고
    • Modulation of Leishmania donovani infection and cell viability by testosterone in bone marrow-derived macrophages: Signaling via surface binding sites
    • Liu L, Benten WP, Wang L, Hao X, Li Q, Zhang H, Guo D, Wang Y, Wunderlich F, Qiao Z: Modulation of Leishmania donovani infection and cell viability by testosterone in bone marrow-derived macrophages: signaling via surface binding sites. Steroids 2005;70:604-614.
    • (2005) Steroids , vol.70 , pp. 604-614
    • Liu, L.1    Benten, W.P.2    Wang, L.3    Hao, X.4    Li, Q.5    Zhang, H.6    Guo, D.7    Wang, Y.8    Wunderlich, F.9    Qiao, Z.10


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.