Pharmacological preconditioning with erythropoietin reduces ischemia-reperfusion injury in the small intestine of rats

Life Sciences

Volumn 84, Issue 11-12, 2009, Pages 364-371

  Sayan, Hale ^a   Ozacmak, Veysel Haktan ^a   Sen, Feyza ^b   Cabuk, Mehmet ^b   Atik, Duygu Yoruk ^b   Igdem, Aysenur Akyildiz ^c   Ozacmak, Ihsan Diler ^c  

^a ZONGULDAK KARAELMAS UNIVERSITY   (Turkey)

^b ZONGULDAK KARAELMAS UNIVERSITY   (Turkey)

^c NONE   (Turkey)

Author keywords

Erythropoietin; Intestinal ischemia; Oxidative stress

Indexed keywords

GLUTATHIONE; MALONALDEHYDE; MYELOPEROXIDASE; RECOMBINANT ERYTHROPOIETIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL INFILTRATION; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; HISTOPATHOLOGY; ILEUM; INTESTINE CONTRACTION; INTESTINE INJURY; INTESTINE ISCHEMIA; MALE; NEUTROPHIL; NONHUMAN; OXIDATIVE STRESS; RAT; REPERFUSION INJURY; WISTAR RAT;

ANIMALS; ERYTHROPOIETIN, RECOMBINANT; GLUTATHIONE; HUMANS; ILEUM; INJECTIONS, INTRAPERITONEAL; LEUKOCYTES; MALE; MALONDIALDEHYDE; MUSCLE CONTRACTION; MUSCLE, SMOOTH; OXIDATIVE STRESS; RATS; RATS, WISTAR; REPERFUSION INJURY;

RATTUS; RATTUS NORVEGICUS; RODENTIA;

EID: 60149094852     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.lfs.2008.12.025     Document Type: Article

References (37)

1. Agnello D., Bigini P., Villa P., Menini T., Cerami A., Brines M.L., and Ghezzi P. Erythropoietin exerts an anti-inflammatory effect on the CNS in a model of experimental autoimmune encephalomyelitis. Brain Research 952 (2002) 128-134
2. Aykac G., Uysal M., Yalcin A.S., Kocak-Toker N., Sivas A., and Oz H. The effects of chronic ethanol injection on hepatic lipid peroxide, glutathione, glutathione peroxidase and glutathione transferase in rats. Toxicology 36 (1985) 71-76
3. Bahcekapili N., Uzum G., Gokkusu C., Kuru A., and Ziylan Y.Z. The relationship between erythropoietin pretreatment with blood-brain barrier and lipid peroxidation after ischemia/reperfusion in rats. Life Sciences 13 (2007) 1245-1251
4. Baker J.E. Erythropoietin mimics ischemic preconditioning. Vascular Pharmacology 42 (2005) 233-241
5. Ballabeni V., Barocelli E., Bertoni S., and Impicciatore M. Alterations of intestinal motor responsiveness in a model of mild mesenteric ischemia/reperfusion. Life Sciences 71 (2002) 2025-2035
6. Bielefeldt K., and Conklin J.L. Intestinal motility during hypoxia and reoxygenation in vitro. Digestive Disease Science 42 (1997) 878-884
7. Bradley P.P., Priebat D.A., Christensen R.D., and Rothstein G. Measurement of cutaneous inflammation: estimation of neutrophil content with an enzyme marker. Journal of Investigative Dermatology 78 (1982) 206-209
8. Brines M., and Cerami A. Discovering erythropoietin's extra-hematopoietic functions. Biology and clinical promise. Kidney International 70 (2006) 246-250
9. Brines M.L., Ghezzi P., Kenan S., Agnello D., de Lanerolle N.C., Cerami C., Itri L.M., and Cerami A. Erythropoietin crosses the blood-brain barrier to protect against experimental brain injury. Proceedings of the National Academy of Sciences USA 97 (2000) 10526-10531
10. Burger D., Lei M., Geoghegan-Morphet N., Lu X., Xenocostas A., and Feng Q. Erythropoietin protects cardiomyocytes from apoptosis via up-regulation of endothelial nitric oxide synthase. Cardiovascular Research 72 (2006) 51-59
11. Cai Z., Manalo D.J., Wei G., Rodriguez E.R., Fox-Talbot K., and Lu H. Hearts from rodents exposed to intermittent hypoxia or erythropoietin are protected against ischemia-reperfusion injury. Circulation 108 (2003) 79-85
12. Casini A., Ferrali M., Pampella A., Maellaro E., and Combarti M. Lipid peroxidation and cellular damage in extrahepatic tissues of bromobenzene in toxicated mice. American Journal of Pathology 123 (1989) 520-531
13. Collard C.D., and Gelman S. Pathophysiology, clinical manifestations, and prevention of ischemia-reperfusion injury. Anesthesiology 94 (2001) 1133-1138
14. Cuzzocrea S., Mazzon E., Di Paola R., Patel N.S., Genovese T., Muià C., De Sarro A., and Thiemermann C. Erythropoietin reduces the development of experimental inflammatory bowel disease. Journal of Pharmacology and Experimental Therapeutics 311 3 (2004) 1272-1280
15. Danpure H.J., Osman S., and Carroll M.J. The development of a clinical protocol for the radiolabelling of mixed leucocytes with 99Tcm-hexamethylpropyleneamine oxime. Nuclear Medicine Communucations 9 6 (1988) 465-475
16. Davis D.P., and Patel P.M. Ischemic preconditioning in the brain. Current Opinion in Anaesthesiology 16 5 (2003) 447-452
17. Gallucci M.T., Lubrano R., Meloni C., Morosetti M., Manca di Villahermosa S., Scoppi P., Palombo G., Castello M.A., and Casciani C.U. Red blood cell membrane lipid peroxidation and resistance to erythropoietin therapy in hemodialysis patients. Clinical Nephrology 52 (1999) 239-245
18. Genc S., Akhisaroglu M., Kuralay F., and Genc K. Erythropoietin restores glutathione peroxidase activity in 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine-induced neurotoxicity in C57BL mice and stimulates murine astroglial glutathione peroxidase production in vitro. Neuroscience Letters 321 1-2 (2002) 73-76
19. Grasso G., Sfacteria A., Erbayraktar S., Passalacqua M., Meli F., Gokmen N., Yilmaz O., La Torre D., Buemi M., Iacopino D.G., Coleman T., Cerami A., Brines M., and Tomasello F. Amelioration of spinal cord compressive injury by pharmacological preconditioning with erythropoietin and a nonerythropoietin derivate. Journal of Neurosurgery Spine 4 4 (2006) 310-318
20. Guneli E., Cavdar Z., Islekel H., Sarioglu S., Erbayraktar S., Kiray M., Sokmen S., Yilmaz O., and Gokmen N. Erythropoietin protects the intestine against ischemia/reperfusion injury in rats. Molecular Medicine 13 9-10 (2007) 509-517
21. Haasoun H.T., Weisbrodt N.W., Mercer D.W., Kozar R.A., Moody F.G., and Moore F.A. Inducible nitric oxide synthase mediates gut ischemia/reperfusion-induced ileus only after severe insults. Journal of Surgical Research 97 (2001) 150-154
22. Hierholzer C., Kalff J.C., Audolfsson G., Billiar T.R., Tweardy D.J., and Bauer A.J. Molecular and functional contractile sequelae of rat intestinal ischemia/reperfusion injury. Transplantation 68 (1999) 1244-1254
23. Joyeux-Faure M., Ramond A., Beguin P.C., Belaïdi E., Godin-Ribuot D., and Ribuot C. Early pharmacological preconditioning by erythropoietin mediated by inducible NOS and mitochondrial ATP-dependent potassium channels in the rat heart. Fundamental and Clinical Pharmacology 20 (2006) 51-56
24. Junk A.K., Mammis A., Savitz S.I., Singh M., Roth S., Malhotra S., Rosenbaum P.S., Cerami A., Brines M., and Rosenbaum D.M. Erythropoietin administration protects retinal neurons from acute ischemia-reperfusion injury. Proceedings of the National Academy of Sciences USA 99 16 (2002) 10659-10664
25. Liu X., Shen J., Jin Y., Duan M., and Xu J. Recombinant human erythropoietin (rhEPO) preconditioning on nuclear factor-kappa B (NF-kB) activation & proinflammatory cytokines induced by myocardial ischaemia-reperfusion. Indian Journal of Medical Research, 124 3 (2006) 343-354
26. Liu X., Xie W., Liu P., Duan M., Jia Z., Li W., and Xu J. Mechanism of cardioprotection of rhEPO pretreatment on suppressing the inflammatory response in ischemia-reperfusion. Life Sciences 78 (2006) 2255-2264
27. Lodato R.F., Khan R.A., Zembowicz M.J., Weisbrodt N.W., Pressley T.A., Li Y.F., Lodato J.A., Zembowicz A., and Moody F.G. Roles of IL-1 and TNF in the decreased ileal muscle contractility induced by lipopolysaccaride. American Journal of Physiology Gastrointestinal and Liver Physiology 276 (1999) G1356-G1362
28. Mallick I.H., Yang W., Winslet M.C., and Seifaian A.M. Ischemia-reperfusion injury of the intestine and protective strategies against injury. Digestive Disease Sciences 49 9 (2004) 1359-1377
29. Moon C., Krawczyk M., Paik D., Lakatta E.G., and Talan M.I. Cardioprotection by recombinant human erythropoietin following acute experimental myocardial infarction: dose response and therapeutic window. Cardiovascular Drugs and Therapy 19 4 (2005) 243-250
30. Mori S., Sawada T., Okada T., and Kubota K. Erythropoietin and its derivative protect the intestine from severe ischemia/reperfusion injury in the rat. Surgery 143 4 (2008) 556-565
31. Ozacmak V.H., Sayan H., Arslan S.O., Altaner S., and Aktas R.G. Protective effect of melatonin on contractile activity and oxidative injury induced by ischemia and reperfusion of rat ileum. Life Sciences 76 14 (2005) 1575-1588
32. Ozacmak V.H., Sayan H., Igdem A.A., Cetin A., and Ozacmak I.D. Attenuation of contractile dysfunction by atorvastatin after intestinal ischemia reperfusion injury. European Journal of Pharmacology 562 1-2 (2007) 138-147
33. Rafiee P., Shi Y., Su J., Pritchard Jr. K.A., Tweddell J.S., and Baker J.E. Erythropoietin protects the infant heart against ischemia-reperfusion injury by triggering multiple signaling pathways. Basic Research in Cardiology 100 (2005) 187-197
34. Villa P., Bigini P., Mennini T., Agnello D., Laragione T., Cagnotto A., Viviani B., Marinovich M., Cerami A., Coleman T.R., Brines M., and Ghezzi P. Erythropoietin selectively attenuates cytokine production and inflammation in cerebral ischemia by targeting neuronal apoptosis. Journal of Experimental Medicine 198 (2003) 971-975
35. Yang C.W., Li C., Jung J.Y., Shin S.J., Choi B.S., Lim S.W., Sun B.K., Kim Y.S., Kim J., Chang Y.S., and Bang B.K. Preconditioning with erythropoietin protects against subsequent ischemia-reperfusion injury in rat kidney. FASEB Journal 17 12 (2003) 1754-1755
36. Werner J., Dragotakes S.C., del Castillo C.F., Rivera J.A., Ou J., Rattner D.W., Fischman A.J., and Warshaw A.L. Technetium-99m-labeled white blood cells: a new method to define the local and systemic role of leukocytes in acute experimental pancreatitis. Annals of Surgery 227 1 (1998) 86-94
37. Wu H., Ren B., Zhu J., Dong G., Xu B., Wang C., Zheng X., and Jing H. Pretreatment with recombinant human erythropoietin attenuates ischemia-reperfusion induced lung injury in rats. Euorpean Journal of Cardio-Thoracic Surgery 29 6 (2006) 902-907