Application of phosphonyl carbanions to highly regioselective synthesis of some diazaphospholes and pyrazolinyl phosphonates

European Journal of Medicinal Chemistry

Volumn 44, Issue 2, 2009, Pages 526-532

  Abdou, Wafaa M ^a   Khidre, Maha D ^a   Khidre, Rizk E ^a  

^a NATIONAL RESEARCH CENTRE   (Egypt)

Author keywords

Antimicrobial and antifungal activities; Diazo chemistry; Phosphole and phosphonate derivatives; Structure activity relationship (SAR); Wittig Horner carbanions

Indexed keywords

1 ETHYL 3 (METHYLTHIO)INDENO[2,1 E][4,1,2]OXADIAZIN 9(1H) ONE; 2 DIAZONIO 1,3 DIOXO 2,3 DIHYDRO 1H INDEN 2 IDE; 4 ETHOXY 2 ETHYL 1',3' DIOXO 1',2,3',4 TETRAHYDROSPIRO(1,2,4 DIAZAPHOSPHOLE 3,2' INDENE) 5 CARBONITRILE 4 OXIDE; 4 ETHOXY 2 ETHYL 5 (METHYLTHIO) 2,4 DIHYDROSPIRO(1,2,4 DIAZAPHOSPHOLE 3,2' INDENE) 1',3' DIONE 4 OXIDE; DIAZAPHOSPHOLE DERIVATIVE; DIAZONIUM COMPOUND; DIETHYL (THIOMETHYL)METHYLPHOSPHONATE; DIETHYL [2' ETHYL 1,3 DIOXO 1,2',3,4' TETRAHYDROSPIRO(INDENE 2,3' PYRAZOL) 5' YL]PHOSPHONATE; DIETHYL [2' ETHYL 1,3,4' TRIOXO 1,2',3,4' TETRAHYDROSPIRO(INDENE 2,3' PYRAZOL) 5' YL]PHOSPHONATE; DIETHYL [4' AMINO 1,3 DIOXO 1,3 DIHYDROSPIRO(INDENE 2,3' PYRAZOL) 5' YL]PHOSPHONATE; DIETHYLCYANOMETHYLPHOSPHONATE; DIETHYLPHOSPHONOACETATE DERIVATIVE; DIETHYLVINYLPHOSPHONATE; ETHYL 4 ETHOXY 2 ETHYL 1',3' DIOXO 1',2,3',4 TETRAHYDROSPIRO(1,2,4 DIAZAPHOSPHOLE 3,2' INDENE) 5 CARBOXYLATE 4 OXIDE; METHYL 4 ETHOXY 2 ETHYL 1',3' DIOXO 1',2,3',4 TETRAHYDROSPIRO(1,2,4 DIAZAPHOSPHOLE 3,2' INDENE) 5 CARBOXYLATE 4 OXIDE; OXADIAZINE DERIVATIVE; PHOSPHOLE DERIVATIVE; PHOSPHONIC ACID DERIVATIVE; PHOSPHONYL CARBANION DERIVATIVE; PYRAZOLINYL PHOSPHONATE DERIVATIVE; SPIRO[3']PYRAZOLINYLPHOSPHONATE DERIVATIVE; SPIRO[3]DIAZAPHOSPHOLE; SPIRO[3]DIAZAPHOSPHOLE DERIVATIVE; UNCLASSIFIED DRUG;

ANTIBACTERIAL ACTIVITY; ANTIFUNGAL ACTIVITY; ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CHEMICAL INTERACTION; CHEMICAL REACTION; CYCLOADDITION; DRUG STRUCTURE; DRUG SYNTHESIS; INFRARED SPECTROSCOPY; NONHUMAN; PHOSPHORUS NUCLEAR MAGNETIC RESONANCE; POLYMERIZATION; PROTON NUCLEAR MAGNETIC RESONANCE; STEREOCHEMISTRY; STRUCTURE ACTIVITY RELATION; TECHNIQUE;

ANTI-BACTERIAL AGENTS; ANTIFUNGAL AGENTS; MICROBIAL SENSITIVITY TESTS; PHOSPHONIC ACIDS; PYRAZOLES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 60149087594     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2008.03.032     Document Type: Article

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