Hypercapnia-induced cerebral hyperperfusion: An underrecognized clinical entity

American Journal of Neuroradiology

Volumn 30, Issue 2, 2009, Pages 378-385

  Pollock, J M ^a   Deibler, A R ^a   Whitlow, C T ^a   Tan, H ^a   Kraft, R A ^a   Burdette, J H ^a   Maldjian, J A ^a  

^a WAKE FOREST SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARBON DIOXIDE;

ADOLESCENT; ADULT; AGED; ARTERIAL GAS; ARTICLE; BRAIN BLOOD FLOW; BRAIN DYSFUNCTION; BRAIN METASTASIS; BRAIN PERFUSION; CEREBRAL HYPERPERFUSION; CHILD; CLINICAL ARTICLE; CLINICAL ASSESSMENT; CLINICAL FEATURE; CONTROLLED STUDY; FEMALE; HUMAN; HYPERCAPNIA; INFANT; MALE; MENTAL HEALTH; NEUROIMAGING; NUCLEAR MAGNETIC RESONANCE IMAGING; STROKE; THORAX RADIOGRAPHY;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; BRAIN; CARBON DIOXIDE; CEREBROVASCULAR CIRCULATION; CHILD; CHILD, PRESCHOOL; FEMALE; HUMANS; HYPERCAPNIA; HYPEREMIA; INFANT; LINEAR MODELS; MAGNETIC RESONANCE IMAGING; MALE; MENTAL DISORDERS; MIDDLE AGED; RETROSPECTIVE STUDIES; SPIN LABELS; YOUNG ADULT;

EID: 60149087415     PISSN: 01956108     EISSN: None     Source Type: Journal    
DOI: 10.3174/ajnr.A1316     Document Type: Article

References (64)

1. Busija DW, Heistad DD. Factors involved in the physiological regulation of the cerebral circulation. Rev Physiol Biochem Pharmacol 1984;101:161-211
2. Farad FM, Breese KR, Heistad DD. Cerebral vasodilation duringhypercapnia. Role of glibenclamide-sensitive potassium channels and nitric oxide. Stroke 1994;25:1679-83
3. Madden JA. The effect of carbon dioxide on cerebral arteries. Pharmacol Ther 1993;59:229 -50
4. Claassen JA, Zhang R, Fu Q, et al. Transcranial Doppler estimation of cerebral blood flow and cerebrovascular conductance during modified rebreathing. J Appl Physiol 2007;102:870-77
5. Vavilala MS, Lee LA, Lam AM. Cerebral blood flow and vascular physiology. Anesthesiol Clin North America 2002;20:247-64, v
6. Brian JE, Jr. Carbon dioxide and the cerebral circulation. Anesthesiology 1998;88:1365-86
7. de Boorder MJ, Hendrikse J, van der Grond J. Phase-contrast magnetic resonance imaging measurements of cerebral autoregulation with a breath-hold challenge: a feasibility study. Stroke 2004;35:1350-54
8. Kastrup A, Li TQ, Glover GH, et al. Cerebral blood flow-related signal changes during breath-holding. AJNR Am J Neuroradiol 1999;20:1233-38
9. Koons A, Hegyi T, Merita R, et al. Cerebral vascular responses to changes in carbon dioxide tension in term and preterm infants with apnea. Biol Neonate 2003;84:115-18
10. Vovk A, Cunningham DA, Kowalchuk JM, et al. Cerebral blood flow responses to changes in oxygen and carbon dioxide in humans. Can J Physiol Pharmacol 2002;80:819-27
11. Ito H, Kanno I, Ibaraki M, et al. Effect of aging on cerebral vascular response to PaCO2 changes in humans as measured by positron emission tomography. J Cereb Blood Flow Metab 2002;22:997-1003
12. Noth U, Kotajima F, Deichmann R, et al. Mapping of the cerebral vascular response to hypoxia and hypercapnia using quantitative perfusion MRI at 3 T. NMR Biomed 2008;464-72
13. Noth U, Meadows GE, Kotajima F, et al. Cerebral vascular response to hypercapnia: determination with perfusion MRI at 1.5 and 3.0 Tesla using a pulsed arterial spin labeling technique. J Magn Reson Imaging 2006;24:1229-35
14. Raichle ME, Plum F. Hyperventilation and cerebral blood flow. Stroke 1972;3:566-75
15. Poulin MJ, Liang PJ, Robbins PA. Dynamics of the cerebral blood flow response to step changes in end-tidal PCO2 and PO2 in humans. J Appl Physiol 1996;81:1084-95
16. Ito H, Yokoyama I, Iida H, et al. Regional differences in cerebral vascular response to PaCO2 changes in humans measured by positron emission tomography. J Cereb Blood Flow Metab 2000;20:1264-70
17. Pfefferkorn T, von Stuckrad-Barre S, Herzog J, et al. Reduced cerebrovascular CO(2) reactivity in CADASIL: A transcranial Doppler sonography study. Stroke 2001;32:17-21
18. Ito H, Kanno I, Ibaraki M, et al. Changes in human cerebral blood flow and cerebral blood volume during hypercapnia and hypocapnia measured by positron emission tomography. J Cereb Blood Flow Metab 2003;23:665-70
19. Pattinson KT, Rogers R, Mayhew SD, et al. Pharmacological FMRI: measuring opioid effects on the BOLD response to hypercapnia. J Cereb Blood Flow Metab 2007;27:414-23
20. Poeppel TD, Terborg C, Hautzel H, et al. Cerebral haemodynamics during hypo- and hypercapnia: determination with simultaneous 15O-butanol-PET and transcranial Doppler sonography. Nuklearmedizin 2007;46:93-100
21. Shen Q, Ren H, Duong TQ. CBF, BOLD, CBV, and CMRO(2) fMRI signal temporal dynamics at 500-msec resolution. J Magn Reson Imaging 2008;27:599-606
22. Kulikov VP, Dicheskul ML, Dobrynina KA. [Venous haemodynamics response to hypercapnia]. Ross Fiziol Zh Im I M Sechenova 2007;93:852-59
23. Kastrup A, Kruger G, Neumann-Haefelin T, et al. Assessment of cerebrovascular reactivity with functional magnetic resonance imaging: comparison of CO(2) and breath holding. Magn Reson Imaging2001;19:13- 20
24. LaffeyJG, Kavanagh BP. Hypocapnia. NEngl JMed2002;347:43-53
25. Luh WM, Wong EC, Bandettini PA, et al. QUIPSS II with thin-slice TI1 periodic saturation: a method for improving accuracy of quantitative perfusion imaging using pulsed arterial spin labeling. MagnResonMed1999;41: 1246-54
26. Yang Y, Frank JA, Hou L, et al. Multislice imaging of quantitative cerebral perfusion with pulsed arterial spin labeling. Magn Reson Med 1998;39:825-32
27. Maldjian J, Laurienti P, Burdette J, et al. Clinical implementation of spin tag perfusion magnetic resonance imaging. J Comput Assist Tomogr 2008;32:403-06
28. Friston KJ, Holmes AP, Worsley KJ, et al. Statistical parametric maps in functional imaging: a general linear approach. Human Brain Mapping 1994;2:189-210
29. Deibler AR, Pollock JM, Kraft RA, et al. Arterial spin-labeling in routine clinical practice, part 1: technique and artifacts. AJNR Am J Neuroradiol 2008;29:1228-34
30. Markus HS. Cerebral perfusion and stroke. J Neurol Neurosurg Psychiatry 2004;75:353-61
31. Kastrup A, Happe V, Hartmann C, et al. Gender-related effects of indomethacin on cerebrovascular CO2 reactivity. J Neurol Sci 1999;162:127-32
32. Wang X, Wu J, Li L, et al. Hypercapnic acidosis activates KATP channels in vascular smooth muscles. Circ Res 2003;92:1225-32
33. Ide K, Worthley M, Anderson T, et al. Effects of the nitric oxide synthase inhibitor L-NMMA on cerebrovascular and cardiovascular responsesto hypoxia and hypercapnia in humans. J Physiol 2007;584:321-32
34. Warner DS, Turner DM, Kassell NF. Time-dependent effects of prolonged hypercapnia on cerebrovascular parameters in dogs: acid-base chemistry. Stroke 1987;18:142-49
35. Hino JK, Short BL, Rais-Bahrami K, et al. Cerebral blood flow and metabolism during and after prolonged hypercapnia in newborn lambs. Crit Care Med 2000;28:3505-10
36. Robertson JW, Debert CT, Frayne R, et al. Variability of middle cerebral artery blood flow with hypercapnia in women. Ultrasound Med Biol 2008;34:730-40
37. Vantanajal JS, Ashmead JC, Anderson TJ, et al. Differential sensitivities of cerebral and brachial blood flow to hypercapnia in humans. J Appl Physiol 2007;102:87-93
38. Cohen ER, Ugurbil K, Kim SG. Effect of basal conditions on the magnitude and dynamics of the blood oxygenation level-dependent fMRI response. J Cereb Blood Flow Metab 2002;22:1042-53
39. Raichle ME, Posner JB, Plum F. Cerebral blood flow during and after hyper-ventilation. Arch Neurol 1970;23:394-403
40. Debert CT, Ide K, Poulin MJ. Ventilatory response to hypercapnia in pre-menopausal and post-menopausal women. Adv Exp Med Biol 2008;605:452-57
41. Gatto R, Hoffman WE, Mueller M, et al. Age effects on brain oxygenation during hypercapnia. J Biomed Opt 2007;12:062113
42. PantanoP,BaronJC,Lebrun-GrandieP,etal. Regional cerebral blood flow and oxygen consumption in human aging. Stroke 1984;15:635-41
43. Safonova LP, Michalos A, Wolf U, et al. Age-correlated changes in cerebral hemodynamics assessed by near-infrared spectroscopy. Arch Gerontol Geriatr 2004;39:207-25
44. Yamamoto M, Meyer JS, Sakai F, et al. Aging and cerebral vasodilator responses to hypercarbia: responses in normal aging and in persons with risk factors for stroke. Arch Neurol 1980;37:489-96
45. Miller JD, Smith RR, Holaday HR. Carbon dioxide reactivity in the evaluation of cerebral ischemia. Neurosurgery 1992;30:518 -21
46. Kastrup A, Dichgans J, Niemeier M, et al. Changes of cerebrovascular CO2 reactivity during normal aging. Stroke 1998;29:1311-14
47. Epstein SK, Singh N. Respiratory acidosis. Respir Care 2001;46:366-83
48. Levasseur JE, Wei EP, Kontos HA, et al. Responses of pial arterioles after prolonged hypercapnia and hypoxia in the awake rabbit. J Appl Physiol 1979;46:89 -95
49. Skinhoj E. CBF adaption in man to chronic hypo- and hypercapnia and its relation to CSF pH. Scand J Clin Lab Invest Suppl 1968;102:VIII:A
50. Lassen NA. Brain extracellular pH: the main factor controlling cerebral blood flow. Scand J Clin Lab Invest 1968;22:247-51
51. Clivati A, Ciofetti M, Cavestri R, et al. Cerebral vascular responsiveness in chronic hypercapnia. Chest 1992;102:135-38
52. Zaharchuk G, Martin AJ, Dillon WP. Noninvasive imaging of quantitative cerebral blood flow changes during 100% oxygen inhalation using arterial spin-labeling MR imaging. AJNR Am J Neuroradiol 2008;29:663-67
53. Floyd TF, Clark JM, Gelfand R, et al. Independent cerebral vasoconstrictive effects of hyperoxia and accompanying arterial hypocapnia at 1 ATA. J Appl Physiol 2003;95:2453-61
54. Lu H, Clingman C, Golay X, et al. Determining the longitudinal relaxation time (T1) of blood at 3.0 Tesla. Magn Reson Med 2004;52:679-82
55. Zhernovoi AI, Sharshina LM. [Effects of hematocrit on blood proton relaxation time]. Med Tekh 1997;33-34
56. Deibler AR, Pollock JM, Kraft RA, et al. Arterial spin-labeling in routine clinical practice, part 2: hypoperfusion patterns. AJNR Am J Neuroradiol 2008;29:1235-41
57. Iadecola C,ZhangF. Nitric oxide-dependent and -independent components of cerebrovasodilation elicited by hypercapnia. Am J Physiol 1994;266:R546-52
58. Reivich M. Arterial PCO2 and cerebral hemodynamics. Am J Physiol 1964;206:25-35
59. Raichle ME, Stone HL. Cerebral blood flow autoregulation and graded hypercapnia. Eur Neurol 1971;6:1-5
60. Coles JP, Fryer TD, Coleman MR, et al. Hyperventilation following head injury: effect on ischemic burden and cerebral oxidative metabolism. Crit Care Med 2007;35:568 -78
61. Ito H, Kanno I, Ibaraki M, et al. Relationship between baseline cerebral blood flow and vascular responses to changes in PaCO2 measured by positron emission tomography in humans: implication of inter-individual variations of cerebral vascular tone. Acta Physiol (Oxf) 2008;193:325-30
62. Petruk KC, Weir BK, Overton TR, et al. The effect of graded hypocapnia and hypercapnia on regional cerebral blood flow and cerebral vessel caliber in the rhesus monkey: study of cerebral hemodynamics following subarachnoid hemorrhage and traumatic internal carotid spasm. Stroke 1974;5:230-36
63. Kirsch DB, Jozefowicz RF. Neurologic complications of respiratory disease. Neurol Clin 2002;20:247-64, viii
64. Halpern P, Raskin Y, Sorkine P, et al. Exposure to extremely high concentrations of carbon dioxide: a clinical description of a mass casualty incident. Ann Emerg Med 2004;43:196 -99