Chelated iron as an anti-Pseudomonas aeruginosa biofilm therapeutic strategy

Journal of Applied Microbiology

Volumn 106, Issue 3, 2009, Pages 1058-

  Reid, D W ^a   O'May, C ^a   Roddam, L F ^a   Lamont, I L ^b  

^a UNIVERSITY OF TASMANIA   (Australia)

^b UNIVERSITY OF OTAGO   (New Zealand)

Author keywords

[No Author keywords available]

Indexed keywords

IRON;

PSEUDOMONAS AERUGINOSA; THERAPEUTIC STRATEGY;

BIOFILMS;

IRON CHELATE;

ANTIBACTERIAL ACTIVITY; BACTERIAL GROWTH; BACTERIUM CULTURE; BIOFILM; CULTURE MEDIUM; CYSTIC FIBROSIS; EPITHELIUM CELL; HOMEOSTASIS; IN VIVO STUDY; IRON CHELATION; IRON DEPLETION; LETTER; NONHUMAN; PHENOTYPE; PHENOTYPIC PLASTICITY; PSEUDOMONAS AERUGINOSA;

PSEUDOMONAS AERUGINOSA;

EID: 60049095699     PISSN: 13645072     EISSN: 13652672     Source Type: Journal    
DOI: 10.1111/j.1365-2672.2008.03955.x     Document Type: Letter

References (3)

1. Moreau-Marquis, S., Bomberger, J.M., Anderson, G.G., Swiatecka-Urban, A., Ye, S., O'Toole, G.A. Stanton, B.A. (2008) The {Delta}F508-CFTR mutation results in increased biofilm formation by P. aeruginosa by increasing iron availability. Am J Physiol Lung Cell Mol Physiol 295, L25 37.
2. Musk, D.J., Jr. Hergenrother, P.J. (2008) Chelated iron sources are inhibitors of Pseudomonas aeruginosa biofilms and distribute efficiently in an in vitro model of drug delivery to the human lung. J Appl Microbiol 105, 380 388.
3. Reid, D.W., Carroll, V., O'May, C., Champion, A. Kirov, S.M. (2007) Increased airway iron as a potential factor in the persistence of Pseudomonas aeruginosa infection in cystic fibrosis. Eur Respir J 30, 286 292.