Comprehensive profiling of epstein-barr virus microRNAs in nasopharyngeal carcinoma

Journal of Virology

Volumn 83, Issue 5, 2009, Pages 2357-2367

  Cosmopoulos, Katherine ^a   Pegtel, Michiel ^b   Hawkins, Jared ^a   Moffett, Howell ^c,d   Novina, Carl ^c,d   Middeldorp, Jaap ^b   Thorley Lawson, David A ^a  

^a TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b VU UNIVERSITY MEDICAL CENTER   (Netherlands)

^c DANA FARBER CANCER INSTITUTE   (United States)

^d HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MICRORNA; RNA; VIRUS RNA;

ARTICLE; BHRF1 GENE; CANCER CELL CULTURE; COMPARATIVE STUDY; CONTROLLED STUDY; DISEASE ASSOCIATION; EPSTEIN BARR VIRUS; GENE; GENE EXPRESSION; HUMAN; HUMAN CELL; NASOPHARYNX CARCINOMA; PRIMARY TUMOR; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TUMOR CELL; CARCINOMA; GENE EXPRESSION PROFILING; GENETICS; NASOPHARYNX TUMOR; SENSITIVITY AND SPECIFICITY; TUMOR CELL LINE; VIROLOGY; VIRUS INFECTION;

HUMAN HERPESVIRUS 4;

CARCINOMA; CELL LINE, TUMOR; EPSTEIN-BARR VIRUS INFECTIONS; GENE EXPRESSION PROFILING; HERPESVIRUS 4, HUMAN; HUMANS; MICRORNAS; NASOPHARYNGEAL NEOPLASMS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, VIRAL; SENSITIVITY AND SPECIFICITY;

EID: 60049091297     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.02104-08     Document Type: Article

References (40)

1. Ambros, V., and R. C. Lee. 2004. Identification of microRNAs and other tiny noncoding RNAs by cDNA cloning. Methods Mol. Biol. 265:131-158.
2. Arrand, J. R., L. S. Young, and J. D. Tugwood. 1989. Two families of sequences in the small RNA-encoding region of Epstein-Barr virus (EBV) correlate with EBV types A and B. J. Virol. 63:983-986.
3. Barth, S., T. Pfuhl, A. Mamiani, C. Ehses, K. Roemer, E. Kremmer, C. Jaker, J. Hock, G. Meister, and F. A. Grasser. 2008. Epstein-Barr virus- encoded microRNA miR-BART2 down-regulates the viral DNA polymerase BALF5. Nucleic Acids Res. 36:666-675.
4. Brooks, L. A., A. L. Lear, L. S. Young, and A. B. Rickinson. 1993. Transcripts from the Epstein-Barr virus BamHI A fragment are detectable in all three forms of virus latency. J. Virol. 67:3182-3190.
5. Cai, X., C. H. Hagedorn, and B. R. Cullen. 2004. Human microRNAs are processed from capped, polyadenylated transcripts that can also function as mRNAs. RNA 10:1957-1966.
6. Cai, X., A. Schafer, S. Lu, J. P. Bilello, R. C. Desrosiers, R. Edwards, N. Raab-Traub, and B. R. Cullen. 2006. Epstein-Barr virus microRNAs are evolutionarily conserved and differentially expressed. PLoS Pathog. 2:e23.
7. Cameron, J. E., Q. Yin, C. Fewell, M. Lacey, J. McBride, X. Wang, Z. Lin, B. C. Schaefer, and E. K. Flemington. 2008. Epstein-Barr virus latent membrane protein 1 induces cellular MicroRNA miR-146a, a modulator of lymphocyte signaling pathways. J. Virol. 82:1946-1958.
8. Chen, C., D. A. Ridzon, A. J. Broomer, Z. Zhou, D. H. Lee, J. T. Nguyen, M. Barbisin, N. L. Xu, V. R. Mahuvakar, M. R. Andersen, K. Q. Lao, K. J. Livak, and K. J. Guegler. 2005. Real-time quantification of microRNAs by stem-loop RT-PCR. Nucleic Acids Res. 33:e179.
9. Chen, H. L., M. M. Lung, J. S. Sham, D. T. Choy, B. E. Griffin, and M. H. Ng. 1992. Transcription of BamHI-A region of the EBV genome in NPC tissues and B cells. Virology 191:193-201.
10. Edwards, R. H., A. R. Marquitz, and N. Raab-Traub. 2008. Epstein-Barr virus BART microRNAs are produced from a large intron prior to splicing. J. Virol. 82:9094-9106.
11. Fields, B. N., D. M. Knipe, and P. M. Howley. 2007. Fields' virology, 5th ed. Wolters Kluwer Health/Lippincott/The Williams & Wilkins Co., Philadelphia, PA.
12. Filipowicz, W., S. N. Bhattacharyya, and N. Sonenberg. 2008. Mechanisms of posttranscriptional regulation by microRNAs: are the answers in sight? Nat. Rev. Genet. 9:102-114.
13. Garofalo, M., G. Condorelli, and C. M. Croce. 2008. MicroRNAs in diseases and drug response. Curr. Opin. Pharmacol. 8:661-667.
14. Gilligan, K. J., P. Rajadurai, J. C. Lin, P. Busson, M. Abdel-Hamid, U. Prasad, T. Tursz, and N. Raab-Traub. 1991. Expression of the Epstein-Barr virus BamHI A fragment in nasopharyngeal carcinoma: evidence for a viral protein expressed in vivo. J. Virol. 65:6252-6259.
15. Glickman, J. N., J. G. Howe, and J. A. Steitz. 1988. Structural analyses of EBER1 and EBER2 ribonucleoprotein particles present in Epstein-Barr virus-infected cells. J. Virol. 62:902-911.
16. Grundhoff, A., C. S. Sullivan, and D. Ganem. 2006. A combined computational and microarray-based approach identifies novel microRNAs encoded by human gamma-herpesviruses. RNA 12:733-750.
17. He, L., and G. J. Hannon. 2004. MicroRNAs: small RNAs with a big role in gene regulation. Nat. Rev. Genet. 5:522-531.
18. Joncas, J., J. Boucher, M. Granger-Julien, and C. Filion. 1974. Epstein-Barr virus infection in the neonatal period and in childhood. Can. Med. Assoc. J. 110:33-37.
19. Kim do, N., H. S. Chae, S. T. Oh, J. H. Kang, C. H. Park, W. S. Park, K. Takada, J. M. Lee, W. K. Lee, and S. K. Lee. 2007. Expression of viral microRNAs in Epstein-Barr virus-associated gastric carcinoma. J. Virol. 81:1033-1036.
20. Kong, W., J. J. Zhao, L. He, and J. Q. Cheng. 2009. Strategies for profiling microRNA expression. J. Cell Physiol. 218:22-25.
21. Lo, A. K., K. F. To, K. W. Lo, R. W. Lung, J. W. Hui, G. Liao, and S. D. Hayward. 2007. Modulation of LMP1 protein expression by EBV-encoded microRNAs. Proc. Natl. Acad. Sci. USA 104:16164-16169.
22. Masucci, M. G., and I. Ernberg. 1994. Epstein-Barr virus: adaptation to a life within the immune system. Trends Microbiol. 2:125-130.
23. Nanbo, A., K. Inoue, K. Adachi-Takasawa, and K. Takada. 2002. Epstein-Barr virus RNA confers resistance to interferon-alpha-induced apoptosis in Burkitt's lymphoma. EMBO J. 21:954-965.
24. Niederman, J. C., R. W. McCollum, G. Henle, and W. Henle. 1968. Infectious mononucleosis: clinical manifestations in relation to EB virus antibodies. JAMA 203:205-209.
25. Niedobitek, G., A. Agathanggelou, and J. M. Nicholls. 1996. Epstein-Barr virus infection and the pathogenesis of nasopharyngeal carcinoma: viral gene expression, tumour cell phenotype, and the role of the lymphoid stroma. Semin. Cancer Biol. 7:165-174.
26. Nilsson, K., G. Klein, W. Henle, and G. Henle. 1971. The establishment of lymphoblastoid lines from adult and fetal human lymphoid tissue and its dependence on EBV. Int. J. Cancer 8:443-450.
27. Pfeffer, S., A. Sewer, M. Lagos-Quintana, R. Sheridan, C. Sander, F. A. Grasser, L. F. van Dyk, C. K. Ho, S. Shuman, M. Chien, J. J. Russo, J. Ju, G. Randall, B. D. Lindenbach, C. M. Rice, V. Simon, D. D. Ho, M. Zavolan, and T. Tuschl. 2005. Identification of microRNAs of the herpesvirus family. Nat. Methods 2:269-276.
28. Pfeffer, S., M. Zavolan, F. A. Grasser, M. Chien, J. J. Russo, J. Ju, B. John, A. J. Enright, D. Marks, C. Sander, and T. Tuschl. 2004. Identification of virus-encoded microRNAs. Science 304:734-736.
29. Rosa, M. D., E. Gottlieb, M. R. Lerner, and J. A. Steitz. 1981. Striking similarities are exhibited by two small Epstein-Barr virus-encoded ribonu- cleic acids and the adenovirus-associated ribonucleic acids VAI and VAII. Mol. Cell. Biol. 1:785-796.
30. Sassen, S., E. A. Miska, and C. Caldas. 2008. MicroRNA: implications for cancer. Virchows Arch. 452:1-10.
31. Smith, P. R., O. de Jesus, D. Turner, M. Hollyoake, C. E. Karstegl, B. E. Griffin, L. Karran, Y. Wang, S. D. Hayward, and P. J. Farrell. 2000. Structure and coding content of CST (BART) family RNAs of Epstein-Barr virus. J. Virol. 74:3082-3092.
32. Stevens, S. J., S. A. Verkuijlen, B. Hariwiyanto, D. K. Harijadi, Paramita, J. Fachiroh, M. Adham, I. B. Tan, S. M. Haryana, and J. M. Middeldorp. 2006. Noninvasive diagnosis of nasopharyngeal carcinoma: nasopharyngeal brushings reveal high Epstein-Barr virus DNA load and carcinoma-specific viral BARF1 mRNA. Int. J. Cancer 119:608-614.
33. Thorley-Lawson, D. A. 2005. EBV the prototypical human tumor virus-just how bad is it? J. Allergy Clin. Immunol. 116:251-262.
34. Thorley-Lawson, D. A. 2001. Epstein-Barr virus: exploiting the immune system. Nat. Rev. Immunol. 1:75-82.
35. van Beek, J., A. A. Brink, M. B. Vervoort, M. J. van Zijp, C. J. Meijer, A. J. van den Brule, and J. M. Middeldorp. 2003. In vivo transcription of the Epstein-Barr virus (EBV) BamHI-A region without associated in vivo BARF0 protein expression in multiple EBV-associated disorders. J. Gen. Virol. 84:2647-2659.
36. Wang, F., C. Gregory, C. Sample, M. Rowe, D. Liebowitz, R. Murray, A. Rickinson, and E. Kieff. 1990. Epstein-Barr virus latent membrane protein (LMP1) and nuclear proteins 2 and 3C are effectors of phenotypic changes in B lymphocytes: EBNA-2 and LMP1 cooperatively induce CD23. J. Virol. 64:2309-2318.
37. Wu, H., J. R. Neilson, P. Kumar, M. Manocha, P. Shankar, P. A. Sharp, and N. Manjunath. 2007. miRNA profiling of naive, effector and memory CD8 T cells. PLoS ONE. 2:e1020.
38. Xia, T., A. O'Hara, I. Araujo, J. Barreto, E. Carvalho, J. B. Sapucaia, J. C. Ramos, E. Luz, C. Pedroso, M. Manrique, N. L. Toomey, C. Brites, D. P. Dittmer, and W. J. Harrington, Jr. 2008. EBV microRNAs in primary lymphomas and targeting of CXCL-11 by ebv-mir-BHRF1-3. Cancer Res. 68:1436-1442.
39. Xing, L., and E. Kieff. 2007. Epstein-Barr virus BHRF1 micro- and stable RNAs during latency III and after induction of replication. J. Virol. 81:9967-9975.
40. Zhang, L., K. Hong, J. Zhang, and J. S. Pagano. 2004. Multiple signal transducers and activators of transcription are induced by EBV LMP-1. Virology 323:141-152.