Neurobiological underpinnings of psychotherapeutic interventions;Neurobiologische grundlagen von psychotherapeutischen interventionen

Zeitschrift fur Psychiatrie, Psychologie und Psychotherapie

Volumn 57, Issue 2, 2009, Pages 97-104

  Bohus, Martin ^a,b   Mauchnik, Jana ^a,b   Schmahl, Christian ^a,b  

^a Klinik für Psychosomatische Medizin und Psychotherapie   (Germany)

^b CENTRAL INSTITUTE OF MENTAL HEALTH   (Germany)

Author keywords

Dissociation; Emotional learning; Mediators; Moderators

Indexed keywords

COGNITION; DEPRESSION; EMOTION; HUMAN; LEARNING; MENTAL DISEASE; PSYCHOTHERAPY; REVIEW; RISK FACTOR;

EID: 59949099241     PISSN: 16614747     EISSN: None     Source Type: Journal    
DOI: 10.1024/1661-4747.57.2.97     Document Type: Review

References (50)

1. Barad, M., Gean, P. W. & Lutz, B. (2006). The role of the amygdala in the extinction of conditioned fear. Biological Psychology, 60, 322-328.
2. Baron, R. M. & Kenny, D. A. (1986). The moderator-mediator variable distinction in social psychological research: Conceptual, strategic, and statistical considerations. Journal of Personality and Social Psychology, 51, 1173-1182.
3. Baum, M. (1988). Spontaneous recovery from the effects of flooding (exposure) in animals. Behaviour Research and Therapy, 26, 185-186.
4. Baxter, L. R., Schwartz, J. M., Bergman, K. S., Szuba, M. P., Guze, B. H., Mazziotta, J. C. et al. (1992). Caudate glucose metabolic rate changes with both drug and behavior therapy for obsessive compulsive disorder. Archives of General Psychiatry, 49, 681-689.
5. Bechara, A., Tranel, D., Damasio, H., Adolphs, R., Rockland, C. & Damasio, A. R. (1995). Double dissociation of conditioning and declarative knowledge relative to the amygdala and hippocampus in humans. Science, 269, 1115-1118.
6. Beutel, M. E., Stern, E. & Silbersweig, D. A. (2003). The emerging dialogue between psychoanalysis and neuroscience: Neuroimaging perspectives. Journal of the American Psychoanalytic Association, 51, 773-801.
7. Bohus, M. (2006). Bausteine einer allgemeinen Psychotherapie. Vortrag auf dem Kongress der Deutschen Gesellschaft für Psychiatrie, Psychotherapie und Nervenheilkunde.
8. Bohus, M., Haaf, B., Simms, T., Schmahl, C., Uncke, C. & Linehan, M. (2004). Effectiveness of inpatient dialectical behavioral therapy for borderline personality disorder: A controlled trial. Behaviour Research and Therapy, 42, 487-499.
9. Bohus, M., Landwehrmeyer, B., Stiglmayr, C., Limberger, M., Böhme, R. & Schmahl, C. (1999). Naltrexone in the treatment of dissociative symptoms in patients with borderline personality disorder: An open-label trial. Journal of Clinical Psychiatry, 60, 598-603.
10. Bouton, M. E. (1988). Context and ambiguity in the extinction of emotional learning: Implications for exposure therapy. Behavior Research and Therapy, 26, 137-149.
11. Bouton, M. E. (1991). Context and retrieval in extinction and in other examples of interference in simple associative learning. In L. Dachowski & C. F. Flaherty (Eds.), Current topics in animal learning: Brain, emotion, and cognition (pp. 25-53). Hillsdale, NJ: Erlbaum.
12. Bouton, M. E. & King, D. A. (1983). Contextual control of the extinction of conditioned fear: Tests for the associative value of the context. Journal of Experimental Psychology: Animal Behavior Processes, 9, 248-265.
13. Bouton, M. E., Mineka, S. & Barlow, D. H. (2001). A modern learning theory perspective on the etiology of panic disorder. Psychological Review, 108, 4-32.
14. Bouton, M. E., Garcia-Gutierrez, A., Zilski, J. & Moody, E. W. (2006). Extinction in multiple contexts does not necessarily make extinction less vulnerable to relapse. Behaviour Research and Therapy, 44, 983-994.
15. Braakmann, D., Ludewig, S., Milde, J., Stiglmayr, C., Hüppe, M., Sipos, V. et al. (2007). Dissoziative Symptome im Verlauf der Behandlung der Borderline-Störung. Psychotherapie Psychosomatik und Medizinische Psychologie, 3/4, 154-160.
16. Collins, B. N. & Brandon, T. H. (2002). Effects of extinction context and retrieval cues on alcohol cue reactivity among nonalcoholic drinkers. Journal of Consulting and Clinical Psychology, 70, 390-397.
17. Davis, M., Ressler, K., Rothbaum, B. O. & Richardson, R. (2006). Effects of D-cycloserine on extinction: Translation from preclinical to clinical work. Biological Psychiatry, 60, 369-375.
18. Dörner, D. (2003). Die Logik des Misslingens. Strategisches Denken in komplexen Situationen. Hamburg: Rowohlt.
19. Ebner-Priemer, U. W., Mauchnik, J., Kleindienst, N., Schmahl, C., Peper, M., Rosenthal, Z. et al. (submitted). Emotional learning during dissociative states in borderline personality disorder.
20. Etkin, A., Pittenger, M., Polan, H. & Kandel, E. (2005). Towards a neurobiology of psychotherapy: Basic science and clinical applications. Journal of Neuropsychiatry and Clinical Neurosciences, 17, 145-158.
21. Freud, S. (1950). Project for a scientific psychology (1950 [1895]). The standard edition of the complete psychological works of Sigmund Freud, Volume I (1886-1899): Pre-psycho-analytic Publications and Unpublished Drafts, 281-391.
22. Grabe, H. J., Spitzer, C. & Freyberger, H. J. (1999). Relationship of dissociation to temperament and character in men and women. American Journal of Psychiatry, 156, 1811-1813.
23. Guastella, A. J., Dadds, M. R., Lovibond, P. F., Mitchell, P. & Richardson, R. (2007). A randomized controlled trial of the effect of D-cycloserine on exposure therapy for spider fear. Journal of Psychiatric Research, 41, 466-471.
24. Guastella, A. J., Richardson, R., Lovibond, P. F., Rapee, R. M., Gaston, J. E., Mitchell, P. et al. (2008). A randomized controlled trial of D-cycloserine enhancement of exposure therapy for social anxiety disorder. Biological Psychiatry, 63, 544-549.
25. Hermans, D., Craske, M. G., Mineka, S. & Lovibond, P. F. (2006). Extinction in human fear conditioning. Biological Psychiatry, 60, 361-368.
26. Herry, C. & Mons, N. (2004). Resistance to extinction is associated with impaired immediate early gene induction in medial prefrontal cortex and amygdala. European Journal of Neuroscience, 20, 781-790.
27. Hofmann, S. G., Meuret, A. E., Smits, J. A., Simon, N. M., Pollack, M. H., Eisenmenger, K. et al. (2006). Augmentation of exposure therapy with D-cycloserine for social anxiety disorder. Archives of General Psychiatry, 63, 298-304.
28. Johannsen, P. & Hoeglend, P. (2007). Identifying mechanisms of change in psychotherapy: Mediators of treatment outcome. Clinical Psychology and Psychotherapy, 14, 1-9.
29. Kandel, E. R. (1998). A new intellectual framework for psychiatry. American Journal of Psychiatry, 155, 457-469.
30. Kirsch, I., Deacon, B., Huedo-Medina, T., Scoboria, A., Moore, T. & Johnson, B. (2008). Initial severity and antidepressant benefits: A meta-analysis of data submitted to the food and drug administration. PLoS Medicine, 5, 260-267.
31. Kleindienst, N., Limberger, M. F., Ebner-Priemer, U. W., Mauchnik, J., Schmahl, C. & Bohus, M. (submitted). Dissociation predicts poor response to Dialectial Behavioral Therapy in female patients with Borderline Personality Disorder.
32. Krämer, H. C., Wilson, G. T., Fairburn, C. G. & Agras, W. S. (2002). Mediators and moderators of treatment effects in randomized clinical trials. Archives of General Psychiatry, 59, 877-883.
33. Kröger, C. (2002). Komorbidität und Prädiktoren für den Therapieerfolg bei der Borderline- Persönlichkeitsstörung. Verfügbar unter http://www.opus- bayern.de/uni-bamberg/volltexte/2005/27/pdf/kroegerges.pdf [22.12.2008].
34. Kushner, M. G., Kim, S. W., Donahue, C., Thuras, P., Adson, D., Kotlyar, M. et al. (2007). D-cycloserine augmented exposure therapy for obsessive-compulsive disorder. Biological Psychiatry, 62, 835-838.
35. Lipsey, M. W. & Wilson, D. B. (1993). The efficacy of psychological, educational, and behavioural treatment: Confirmation from meta-analysis. American Psychologist, 48, 1181-1209.
36. Michelson, L., Vives, A., Testa, S., Marchione, N. & Kimberly, J. (1998). The role of trauma and dissociation in cognitive-behavioral psychotherapy outcome and maintenance for panic disorder with agoraphobia. Behaviour Research and Therapy, 36, 1011-1050.
37. Moody, E. W., Sunsay, C. & Bouton, M. E. (2006). Priming and trial spacing in extinction: Effects on extinction performance, spontaneous recovery, and reinstatement in appetitive conditioning. The Quarterly Journal of Experimental Psychology, 59, 809-829.
38. Phelps, E. A. & LeDoux, J. E. (2005). Contributions of the amygdala to emotion processing: From animal models to human behavior. Neuron, 48, 175-187.
39. Rescorla, R. A. & Heth, C. D. (1975). Reinstatement of fear to an extinguished conditioned stimulus. Journal of Neuroscience, 22, 7892-7902.
40. Ressler, K. J., Rothbaum, B. O., Tannenbaum, L., Anderson, P., Graap, K., Zimand, E. et al. (2004). Cognitive enhancers as adjuncts to psychotherapy: Use of D-cycloserine in phobic individuals to facilitate extinction of fear. Archives of General Psychiatry, 61, 1136-1144.
41. Roth, G. (2007). Die Veränderbarkeit menschlichen Verhaltens aus Sicht der Hirnforschung. Vortrag auf dem Kongress «Neurobiologie der Psychotherapie», München, 6. Juli 2007.
42. Rothbaum, B. O. (2008). Critical parameters for D-cycloserine enhancement of cognitive-behaviorial therapy for obsessive-compulsive disorder. American Journal of Psychiatry, 165, 293-296.
43. Rufer, M., Held, D., Cremer, J., Fricke, S., Moritz, S., Peter, H. et al. (2006). Dissociation as a predictor of cognitive behavior therapy outcome in patients with obsessive-compulsive disorder. Psychotherapy and Psychosomatics, 75, 40-46.
44. Spitzer, C., Barnow, S., Freyberger, H. J. & Grabe, H. J. (2007). Dissociation predicts symptom-related treatment outcome in short-term inpatient psychotherapy. Australian and New Zealand Journal of Psychiatry, 41, 682-687.
45. Teasdale, J. D., Pope, M., Moore, R. G., Hayhurst, H., Williams, S. & Segal, Z. V. (2002). Metacognitive awareness and prevention of relapse in depression: Empirical evidence. Journal of Consulting and Clinical Psychology, 69, 347-357.
46. Tsao, J. C. I. & Craske, M. G. (2000). Timing of treatment and return of fear: Effects of massed, uniform-, and expanding-spaced exposure schedules. Behavior Therapy, 31, 479-497.
47. Vansteenwegen, D., Vervliet, B., Iberico, C., Baeyens, F., Van den Bergh, O. & Hermans, D. (2007). The repeated confrontation with videotapes of spiders in multiple contexts attenuates renewal of fear in spider-anxious students. Behaviour Research and Therapy, 45, 1169-1179.
48. Walker, D. L., Ressler, K. J., Lu, K. T. & Davis, M. (2002). Facilitation of conditioned fear extinction by systemic administration or intra-amygdala infusions of D-cycloserine as assessed with fear-potentiated startle in rats. Journal of Neuroscience, 22, 2343-2351.
49. Wilhelm, S., Buhlmann, U., Tolin, D. F., Meunier, S. A., Pearlson, G. D., Reese, H. E. et al. (2008). Augmentation of behavior therapy with D-cycloserine for obsessive-compulsive disorder. American Journal of Psychiatry, 165, 335-341.
50. Williams, L. M., Phillips, M. L., Brammer, M. J., Skerrett, D., Lagopoulos, J., Rennie, C. et al. (2001). Arousal dissociates amygdala and hippocampal fear responses: Evidence from simultaneous fMRI and skin conductance recording. Neuroimage, 14, 1070-1079.