Vertebral fractures are associated with increased cortical porosity in iliac crest bone biopsy of men with idiopathic osteoporosis

Bone

Volumn 44, Issue 3, 2009, Pages 413-417

  Ostertag, Agnès ^a   Cohen Solal, Martine ^a   Audran, Maurice ^b   Legrand, Erick ^b   Marty, Caroline ^a   Chappard, Daniel ^b   de Vernejoul, Marie Christine ^a  

^a INSERM   (France)

^b UNIVERSITÉ D'ANGERS   (France)

Author keywords

Bone histomorphometry; Cortical bone; Fracture; Men with osteoporosis

Indexed keywords

ADULT; AGED; ARTICLE; BONE MARROW BIOPSY; CONTROLLED STUDY; CORTICAL BONE; DISEASE ASSOCIATION; HUMAN; HUMAN TISSUE; IDIOPATHIC OSTEOPOROSIS; MAJOR CLINICAL STUDY; MALE; MORPHOMETRICS; POROSITY; PREVALENCE; TRABECULAR BONE; VERTEBRA FRACTURE;

ADULT; AGED; BIOPSY; BONE DENSITY; CROSS-SECTIONAL STUDIES; FEMALE; HUMANS; ILIUM; MALE; MIDDLE AGED; OSTEOPOROSIS; SPINAL FRACTURES;

EID: 59949098865     PISSN: 87563282     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bone.2008.11.004     Document Type: Article

References (39)

1. Cummings S.R., and Melton L.J. Epidemiology and outcomes of osteoporotic fractures. Lancet 359 (2002) 1761-1767
2. Van der Klift M., De Laet C.E., McCloskey E.V., Hofman A., and Pols H.A. The incidence of vertebral fractures in men and women: the Rotterdam Study. J. Bone. Miner. Res. 17 (2002) 1051-1056
3. O'Neill T.W., Felsenberg D., Varlow J., Cooper C., Kanis J.A., and Silman A.J. The prevalence of vertebral deformity in European men and women: the European Vertebral Osteoporosis Study. J. Bone Miner. Res. 11 (1996) 1010-1018
4. Szulc P., Munoz F., Duboeuf F., Marchand F., and Delmas P.D. Bone mineral density predicts osteoporotic fractures in elderly men: the MINOS study. Osteoporos. Int. 16 (2005) 1184-1192
5. Schuit S.C., van der Klift M., Weel A.E., et al. Fracture incidence and association with bone mineral density in elderly men and women: the Rotterdam Study. Bone 34 (2004) 195-202
6. Bouxsein M.L. Determinants of skeletal fragility. Best. Pract. Res. Clin. Rheumatol. 19 (2005) 897-911
7. Parfitt A.M., Mathews C.H., Villanueva A.R., Kleerekoper M., Frame B., and Rao D.S. Relationships between surface, volume, and thickness of iliac trabecular bone in aging and in osteoporosis. Implications for the microanatomic and cellular mechanisms of bone loss. J. Clin. Invest. 72 (1983) 1396-1409
8. Aaron J.E., Makins N.B., and Sagreiya K. The microanatomy of trabecular bone loss in normal aging men and women. Clin. Orthop. Relat. Res. 215 (1987) 260-271
9. Khosla S., Riggs B.L., Atkinson E.J., Oberg A.L., McDaniel L.J., Holets M., et al. Effects of sex and age on bone microstructure at the ultradistal radius: a population-based non invasive in vivo assessment. J. Bone Miner. Res. 21 (2006) 124-131
10. Duan Y., Seeman E., and Turner C.H. The biomechanical basis of vertebral body fragility in men and women. J. Bone Miner. Res. 16 (2001) 2376-2383
11. Kimmel D.B., Recker R.R., Gallagher J.C., Vaswani A.S., and Aloia J.F. A comparison of iliac bone histomorphometric data in post-menopausal osteoporotic and normal subjects. J. Bone Miner. Res. 11 (1990) 217-235
12. Sornay-Rendu E., Boutroy S., Munoz F., and Delmas P.D. Alterations of cortical and trabecular architecture are associated with fractures in postmenopausal women, partially independent of decreased BMD measured by DXA: the OFELY study. J. Bone Miner. Res. 23 (2007) 425-433
13. Legrand E., Chappard D., Pascaretti C., Duquenne M., Krebs S., Rohmer V., et al. Trabecular bone microarchitecture, bone mineral density, and vertebral fractures in male osteoporosis. J. Bone Miner. Res. 15 (2000) 13-19
14. Oleksik A., Ott S.M., Vedi S., Bravenboer N., Compston J., and Lips P. Bone structure in patients with low bone mineral density with or without vertebral fractures. J. Bone Miner. Res. 15 (2000) 1368-1375
15. Qiu S., Rao D.S., Palnitkar S., and Parfitt A.M. Independent and combined contributions of cancellous and cortical bone deficits to vertebral fracture risk in postmenopausal women. J. Bone Miner. Res. 21 (2006) 1791-1796
16. Bilezikian J.P. Osteoporosis in men. J. Clin. Endocrinol. Metab. 84 (1999) 3431-3434
17. de Gennes C., Kuntz D., and de Vernejoul M.C. Bone mastocytosis. A report of nine cases with a bone histomorphometric study. Clin. Orthop. Relat. Res. 279 (1992) 281-291
18. Brumsen C., Papapoulos S.E., Lentjes E.G., Kluin P.M., and Hamdy N.A. A potential role for the mast cell in the pathogenesis of idiopathic osteoporosis in men. Bone 31 (2002) 556-561
19. Parfitt A.M., Drezner M.K., Glorieux F.H., Kanis J.A., Malluche H., Meunier P.J., et al. Bone histomorphometry: standardization of nomenclature, symbols, and units. Report of the ASBMR Histomorphometry Nomenclature Committee. J. Bone Miner. Res. 2 (1987) 595-610
20. Vesterby A. Star volume of marrow space and trabeculae in iliac crest: sampling procedure and correlation to star volume of first lumbar vertebra. Bone 11 (1990) 149-155
21. Brockstedt H., Kassem M., Eriksen E.F., Mosekilde L., and Melsen F. Age- and sex-related changes in iliac cortical bone mass and remodeling. Bone 14 (1993) 681-691
22. McCullagh P., and Nelder J.A. Generalized linear models. 2nd ed. (1989), Chapman and Hall, London
23. Dempster D.W., Ferguson-Pell M.W., Mellish R.W., Cochran G.V., Xie F., Fey C., et al. Relationships between bone structure in the iliac crest and bone structure and strength in the lumbar spine. Osteoporos. Int. 3 (1993) 90-96
24. Thomsen J.S., Ebbesen E.N., and Mosekilde L. Predicting human vertebral bone strength by vertebral static histomorphometry. Bone 30 (2002) 502-508
25. Parfitt A.M. A structural approach to renal bone disease. J. Bone Miner. Res. 13 (1998) 1213-1220
26. Chappard D., Legrand E., Baslé M.F., Fromont P., Racineux J.L., Rebel A., et al. Altered trabecular architecture induced by corticosteroids: a bone histomorphometric study. J. Bone Miner. Res. 11 (1996) 676-685
27. Legrand E., Audran M., Guggenbuhl P., Levasseur R., Chalès G., Baslé M.F., et al. Trabecular bone microarchitecture is related to the number of risk factors and etiology in osteoporotic men. Microsc. Res. Tech. 70 (2007) 952-959
28. Seeman E. The structural basis of bone fragility in men. Bone 25 (1999) 143-147
29. Szulc P., and Delmas P.D. Bone loss in elderly men: increased endosteal bone loss and stable periosteal apposition. The prospective MINOS study. Osteoporos. Int. 18 (2007) 495-503
30. Riggs B.L., Melton Iii III L.J., Robb R.A., Camp J.J., Atkinson E.J., Peterson J.M., et al. Population-based study of age and sex differences in bone volumetric density, size, geometry, and structure at different skeletal sites. J. Bone Miner. Res. 19 (2004) 1945-1954
31. Eswaran S.K., Gupta A., Adams M.F., and Keaveny T.M. Cortical and trabecular load sharing in the human vertebral body. J. Bone Miner. Res. 21 (2006) 307-314
32. Schaffler M.B., and Burr D.B. Stiffness of compact bone: effects of porosity and density. J. Biomech. 21 (1988) 13-16
33. McCalden R.W., McGeough J.A., Barker M.B., and Court-Brown C.M. Age-related changes in the tensile properties of cortical bone. The relative importance of changes in porosity, mineralization, and microstructure. J. Bone. Joint. Surg. Am. 751 (1993) 193-205
34. Boutroy S., Bouxsein M.L., Munoz F., and Delmas P.D. In vivo assessment of trabecular bone microarchitecture by high-resolution peripheral quantitative computed tomography. J. Clin. Endocrinol. Metab. 90 (2005) 6508-6515
35. Bousson V., Meunier A., Bergot C., Vicaut E., Rocha M.A., Morais M.H., et al. Distribution of intracortical porosity in human midfemoral cortex by age and gender. J. Bone. Miner. Res. 16 (2001) 1308-1317
36. Thomas C.D., Feik S.A., and Clement J.G. Increase in pore area, and not pore density, is the main determinant in the development of porosity in human cortical bone. J. Anat. 209 (2006) 219-230
37. Bousson V., Peyrin F., Bergot C., Hausard M., Sautet A., and Laredo J.D. Cortical bone in the human femoral neck: three-dimensional appearance and porosity using synchrotron radiation. J. Bone Miner. Res. 19 (2004) 794-801
38. Cooper D.M., Thomas C.D., Clement J.G., Turinsky A.L., Sensen C.W., and Hallgrímsson B. Age-dependent change in the 3D structure of cortical porosity at the human femoral midshaft. Bone 40 (2007) 957-965
39. Bell K.L., Loveridge N., Power J., Garrahan N., Meggitt B.F., and Reeve J. Regional differences in cortical porosity in the fractured femoral neck. Bone 24 (1999) 57-64