Falsely low hemoglobin A 1c levels in a patient receiving ribavirin and peginterferon alfa-2b for hepatitis C

Pharmacotherapy

Volumn 29, Issue 1, 2009, Pages 121-123

  Gross, Benjamin N ^a,b   Cross, L Brian ^a,b   Foard, Joni C ^a,b   Wood, Yelena A ^b  

^a UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

^b Holston Medical Group   (United States)

Author keywords

A1C; Hemoglobin a 1c; Hepatitis c; Interferon; Peginterferon alfa 2b; Ribavirin; Type 2 diabetes mellitus

Indexed keywords

ALANINE AMINOTRANSFERASE; HEMOGLOBIN A1C; PEGINTERFERON ALPHA2B; RIBAVIRIN;

ADULT; ARTICLE; CASE REPORT; DIABETES MELLITUS; DRUG WITHDRAWAL; FALSE NEGATIVE RESULT; GLUCOSE BLOOD LEVEL; HEMATOCRIT; HEMOGLOBIN BLOOD LEVEL; HEPATITIS C; HUMAN; MALE; SIDE EFFECT; TREATMENT DURATION;

ANTIVIRAL AGENTS; DRUG THERAPY, COMBINATION; HEMOGLOBIN A, GLYCOSYLATED; HEPATITIS C; HUMANS; INTERFERON ALFA-2B; MALE; MIDDLE AGED; RIBAVIRIN;

EID: 59949093689     PISSN: 02770008     EISSN: None     Source Type: Journal    
DOI: 10.1592/phco.29.1.121     Document Type: Article

References (20)

1. Centers for Disease Control and Prevention, Department of Health and Human Services. Hepatitis C: fact sheet. May 24, 2005. Available from www.cdc.gov/hepatitis/HCV/HCVfaq. htm. Accessed February 26, 2008.
2. Federal Bureau of Prisons. Guidelines for the prevention and treatment of viral hepatitis. October 2005. Available from www.bop.gov/news/ PDFs/hepatitis.pdf. Accessed February 26, 2008.
3. Lecube A, Hernandez C, Genesca J, Simo R. Glucose abnormalities in patients with hepatitis C virus infection. Diabetes Care 2006;29:1140-9.
4. Lecube A, Hernandez C, Genesca J, Simo, R, Jardi R, Esteban JI. High prevalence of glucose abnormalities in patients with hepatitis C virus infection. Diabetes Care 2005;27:1171-5.
5. Mehta SH, Brancati FL, Sulkowski MS, Strathdee SA, Szklo M, Thomas DL. Prevalence of type 2 diabetes mellitus among person with hepatitis C virus infection in the United States. Ann Intern Med 2000;133:592-9.
6. American Diabetes Association. Total prevalence of diabetes and pre-diabetes, February 2008. Available from www.diabetes.org/diabetes- statistics/prevalence.jsp. Accessed February 26, 2008.
7. Wilson, JF. In the clinic: type 2 diabetes. Ann Intern Med 2007;146:ITC1-16.
8. American Diabetes Association. Position statement: standard of medical care in diabetes-2008. Diabetes Care 2008;31:S12-54.
9. American Diabetes Association. Position statement: tests of glycemia in diabetes. Diabetes Care 2004;27:S91-3.
10. Schrot RJ, Patel KT, Foulis P. Evaluation of inaccuracies in the measurement of glycemia in the laboratory, by glucose meters, and through measurement of hemoglobin A1c. Clin Diabetes 2007;25:43-9.
11. Davie SJ, Gould BJ, Yudkin JS. Effect of vitamin C on glycosylation of proteins. Diabetes 1992;41:167-73.
12. Ceriello A, Giugliano D, Quatraro A, Donzella C, Dipalo G, Lefebyre PJ. Vitamin E reduction of protein glycosylation in diabetes: new prospect for prevention of diabetic complications? Diabetes Care 1991;14:68-72.
13. Sacks DB, Bruns DE, Goldsteind DE, Maclaren NK, McDonald JM, Parrott M. Guidelines and recommendations for laboratory analysis in the diagnosis and management of diabetes mellitus. Clin Chem 2002;48:436-72.
14. Tarim O, Kucukerdogan A, Gunay U, Eralp O, Ercan I. Effects of iron deficiency anemia on hemoglobin A1C in type 1 diabetes mellitus. Pediatr Int 1999;41:357-62.
15. Saudek CD, Derr RL, Kalyani RR. Assessing glycemia in diabetes using self-monitoring blood glucose and hemoglobin A1C. JAMA 2006;295:1688-97.
16. Naranjo CA, Busto U, Sellers EM, et al. A method of estimating the probability of adverse drug reactions. Clin Pharmacol Ther 1981;30:239-45.
17. Polgreen PM, Putz D, Stapleton JT. Inaccurate glycosylated hemoglobin A1C measurements in human immunodeficiency virus-positive patients with diabetes mellitus. Clin Infect Dis 2003;37:e53-6.
18. Greenberg PD, Rosman AS, Eldeiry LS, Naqvi Z, Brau N. Decline in haemoglobin A1 c values in diabetic patients receiving interferon-alpha and ribavirin for chronic hepatitis C. J Viral Hepat 2006;13:613-17.
19. Lahousen T, Hegenbarth K, Ille R, et al. Determination of glycated hemoglobin in patients with advanced liver disease. World J Gastroenterol 2004;10:2284-6.
20. Arnold JG, McGowan HJ. Delay in diagnosis of diabetes mellitus due to inaccurate use of hemoglobin A1C levels. J Am Board Fam Med 2007;20:93-9.