What is the optimal regimen for preventing hepatitis B recurrence after liver transplantation?

Nature Clinical Practice Gastroenterology and Hepatology

Volumn 6, Issue 2, 2009, Pages 68-69

  Degertekin, Bulent ^a   Lok, Anna S ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADEFOVIR; ANTIVIRUS AGENT; ENTECAVIR; HEPATITIS B ANTIBODY; HEPATITIS B SURFACE ANTIBODY; LAMIVUDINE;

ANTIBODY TITER; ANTIVIRAL THERAPY; DRUG DOSE REDUCTION; DRUG MEGADOSE; HEPATITIS B; HEPATITIS B VIRUS; HUMAN; LIVER TRANSPLANTATION; LIVING DONOR; LOW DRUG DOSE; MONOTHERAPY; NOTE; PRIORITY JOURNAL; RECURRENT DISEASE; SURVIVAL; TREATMENT DURATION; VIRUS REPLICATION;

ANTIVIRAL AGENTS; DRUG THERAPY, COMBINATION; HEPATITIS B; HEPATITIS B ANTIBODIES; HUMANS; IMMUNOGLOBULINS; LAMIVUDINE; LIVER TRANSPLANTATION; RECURRENCE; TREATMENT OUTCOME;

EID: 59949091824     PISSN: 17434378     EISSN: 17434386     Source Type: Journal    
DOI: 10.1038/ncpgasthep1339     Document Type: Note

References (10)

1. Samuel D et al. (1993) Liver transplantation in European patients with the hepatitis B surface antigen. N Engl J Med 329: 1842-1847
2. Ghany MG et al. (1998) Hepatitis B virus S mutants in liver transplant recipients who were reinfected despite hepatitis B immune globulin prophylaxis. Hepatology 27: 213-222
3. Roche B et al. (2003) HBV DNA persistence 10 years after liver transplantation despite successful anti-HBS passive immunoprophylaxis. Hepatology 38: 86-95
4. Kim WR et al. (2004) Outcome of liver transplantation for hepatitis B in the United States. Liver Transpl 10: 968-974
5. Hwang S et al. (2008) Prevention of hepatitis B recurrence after living donor liver transplantation: Primary high-dose hepatitis B immunoglobulin monotherapy and rescue antiviral therapy. Liver Transpl 14: 770-778
6. Yao FY et al. (2001) Lamivudine treatment is beneficial in patients with severely decompensated cirrhosis and actively replicating hepatitis B infection awaiting liver transplantation: A comparative study using a matched, untreated cohort. Hepatology 34: 411-416
7. Schiff E et al. (2007) Adefovir dipivoxil for wait-listed and post-liver transplantation patients with lamivudine-resistant hepatitis B: Final long-term results. Liver Transpl 13: 349-360
8. Lok AS and McMahon BJ (2007) Chronic hepatitis B. Hepatology 45 507-539
9. Gane EJ et al. (2007) Lamivudine plus low-dose hepatitis B immunoglobulin to prevent recurrent hepatitis B following liver transplantation. Gastroenterology 132: 931-937
10. Wong SN et al. (2007) Low risk of hepatitis B virus recurrence after withdrawal of long-term hepatitis B immunoglobulin in patients receiving maintenance nucleos(t)ide analogue therapy. Liver Transpl 13: 374-381