Urinary biomarkers of podocyte injury

Biomarkers in Medicine

Volumn 2, Issue 6, 2008, Pages 613-616

  Camici, Marcello ^a  

^a UNIVERSITY OF PISA   (Italy)

Author keywords

Biomarker; Podocyte; Urinary podocyte specific molecules; Urinary podocytes

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 3; ALPHA ACTININ; ALPHA3 INTEGRIN; B7 ANTIGEN; CD2 ASSOCIATED PROTEIN; COMMON ACUTE LYMPHOBLASTIC LEUKEMIA ANTIGEN; COMPLEMENT COMPONENT C3B RECEPTOR; CORTACTIN; CREATININE; CYTOKERATIN; DESMIN; DYSTROGLYCAN; EZRIN; MESSENGER RNA; MYOCILIN; NEPHRIN; PODOCALYXIN; PODOCIN; PODOPLANIN; PROTEIN P21; PROTEIN P27; PROTEIN P57; PROTEIN ZO1; PROTEOME; TRANSFORMING GROWTH FACTOR BETA; TUBULIN; VASCULOTROPIN; VIMENTIN; WT1 PROTEIN;

ARTICLE; CELL COUNT; CELL CULTURE; CREATININE URINE LEVEL; DIAGNOSTIC ACCURACY; DIAGNOSTIC VALUE; DISEASE MARKER; ENZYME LINKED IMMUNOSORBENT ASSAY; EXOSOME; FLOW CYTOMETRY; FLUORESCENCE ACTIVATED CELL SORTING; GENE EXPRESSION; GLOMERULOPATHY; HEALTH CARE COST; HUMAN; IMMUNOBLOTTING; IMMUNOFLUORESCENCE TEST; LIQUID CHROMATOGRAPHY; PODOCYTE; POLYACRYLAMIDE GEL ELECTROPHORESIS; POLYMERASE CHAIN REACTION; PROTEIN EXPRESSION; PROTEINURIA; QUANTITATIVE DIAGNOSIS; SENSITIVITY AND SPECIFICITY; TANDEM MASS SPECTROMETRY; URINE CYTOLOGY;

EID: 59949088515     PISSN: 17520363     EISSN: None     Source Type: Journal    
DOI: 10.2217/17520363.2.6.613     Document Type: Article

References (12)

1. Endlich K, Kriz W, Witzgall R: Update in podocyte biology. Curr. Opin. Nephrol. Hypertens. 10(3), 331-340 (2001).
2. Pavenstadt H, Kriz W, Kretzler M: Cell biology of the glomerular podocyte. Physiol. Rev. 83(1), 253-307 (2003).
3. Asanuma K, Mundel P: The role of podocytes in glomerular pathobiology. Clin. Exp. Nephrol. 7(4), 255-259 (2003).
4. Mundel P, Shankland SJ: Podocyte biology and response to injury. J. Am. Soc. Nephrol. 13(12), 3005-3015 (2002).
5. Vogelmann SU, Nelon WJ, Myers BD, Lemley KV: Urinary excretion of viable podocyces in healthy and renal disease. Am. J. Physiol. Renal Physiol. 285(1), F40-F48 (2003).
6. Bariety J, Mandet C, Hill GS, Bruneval P: Parietal podocytes in normal human glomeruli. J. Am. Soc. Nephrol. 17(10), 2770-2780 (2006).
7. Achenbach J, Mengel M, Tossidou I et al.: Parietal epithelia cells in the urine as a marker of disease activity in glomerular disease. Nephrol. Dial. Transplant. 23(10), 3138-3145 (2008).
8. Morrow DA, de Lemos JA: Benchmarks for the assessment of novel cardiovascular biomarkers. Circulation 115(8), 949-952 (2007).
9. Petermann AT, Krofft R, Blonski M et al.: Podocytes that detach in experimental membranous nephropathy are viable. Kidney Int. 64(4), 1222-1231 (2003).
10. Petermann A, Floege J: Podocyte damage resulting in podocyturia: a potential diagnostic marker to assess glomerular disease activity. Nephron Clin. Pract. 106(2), c61-c66 (2007).
11. Patari A, Forsblom C, Havana M, Taipale H, Groop PH, Holthofer H: Nephrinuria in diabetic nephropathy of Type 1 diabetes. Diabetes 52(12), 2969-2974 (2003).
12. Pisitkun T, Shen RF, Knepper MA: Identification and proteomic profiling of exosomes in human urine. Proc. Natl Acad. Sci. USA 101(36), 13368-13373 (2004).