Mechanisms in hyperkalemic renal tubular acidosis

Journal of the American Society of Nephrology

Volumn 20, Issue 2, 2009, Pages 251-254

  Karet, Fiona E ^a,b  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b ADDENBROOKE S HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ALDOSTERONE; RENIN;

ALDOSTERONE RELEASE; AMMONIA FORMATION; DIABETES MELLITUS; HUMAN; HYPERKALEMIA; HYPOALDOSTERONISM; KIDNEY DYSFUNCTION; KIDNEY TUBULE ACIDOSIS; NEPHRON; POTASSIUM BLOOD LEVEL; PRIORITY JOURNAL; PSEUDOHYPOALDOSTERONISM; SHORT SURVEY;

EID: 59949087149     PISSN: 10466673     EISSN: 15333450     Source Type: Journal    
DOI: 10.1681/ASN.2008020166     Document Type: Short Survey

References (44)

1. Du Bose TD Jr: Acid-base disorders. In: Brenner and Rector's The Kidney, Vol. 1, edited by Brenner BM, Philadelphia, W.B. Saunders Co., 2000, pp 948-962
2. Stone DK, Seldin DW, Kokko JP, Jacobson HR: Mineralocorticoid modulation of rabbit medullary collecting duct acidification: A sodium-independent effect. J Clin Invest 72: 77-83, 1983
3. Winter C, Schulz N, Giebisch G, Geibel JP, Wagner CA: Nongenomic stimulation of vacuolar H+-ATPases in intercalated renal tubule cells by aldosterone. Proc Natl Acad Sci USA 101: 2636-2641, 2004
4. Schambelan M, Sebastian A, Biglieri EG: Prevalence, pathogenesis, and functional significance of aldosterone deficiency in hyperkalemic patients with chronic renal insufficiency. Kidney Int 17: 89-101, 1980
5. Arruda JA, Batlle DC, Sehy JT, Roseman MK, Baronowski RL, Kurtzman NA: Hyperkalemia and renal insufficiency: Role of selective aldosterone deficiency and tubular un-responsiveness to aldosterone. Am J Nephrol 1: 160-167, 1981
6. Abbott EC, Gornall AG, Sutherland DJ, Laid law JC, Stiefel M: The influence of a heparinlike compound on hypertension, electrolytes and aldosterone in man. CMAJ 94: 1155-1164, 1966
7. Kutyrina IM, Nikishova TA, Tareyeva IE: Effects of heparin-induced aldosterone deficiency on renal function in patients with chronic glomerulonephritis. Nephrol Dial Transplant 2: 219-223, 1987
8. Johnson JA, Davis JO, Gotshall RW, Lohmeier TE, Davis JL, Braverman B, Tempel GE: Evidence for an intrarenal beta receptor in control of renin release. Am J Physiol 230: 410-418, 1976
9. Perazella MA: Trimethoprim-induced hyperkalaemia: Clinical data, mechanism, prevention and management. Drug Saf 22:227-236, 2000
10. Velazquez H, Perazella MA, Wright FS, Ellison DH: Renal mechanism of trimethoprim-induced hyperkalemia. Ann Intern Med 119: 296-301, 1993
11. Kleyman TR, Roberts C, Ling BN: A mechanism for pentamidine-induced hyperkalemia: Inhibition of distal nephron sodium transport. Ann Intern Med 122: 103-106, 1995
12. Aker S, Heering P, Kinne-Saffran E, Deppe C, Grabensee B, Kinne RK: Different effects of cyclosporine a and FK506 on potassium transport systems in MDCK cells. Exp Nephrol 9: 332-340, 2001
13. Chang SS, Grunder S, Hanukoglu A, Rosler A, Mathew PM, Hanukoglu I, Schild L, Lu Y, Shimkets RA, Nelson-Williams C, Rossier BC, Lifton RP: Mutations in subunits of the epithelial sodium channel cause salt wasting with hyperkalaemic acidosis, pseudohypoal dosteronism type 1. Nat Genet 12: 248 -253, 1996
14. Strautnieks SS, Thompson RJ, Gardiner RM, Chung E: A novel splice-site mutation in the gamma subunit of the epithelial sodium channel gene in three pseudohypoaldosteronism type 1 families. Nat Genet 13: 248 -250, 1996
15. Geller DS, Rodriguez-Soriano J, Vallo Boado A, Schifter S, Bayer M, Chang SS, Lifton RP: Mutations in the mineralocorticoid receptor gene cause autosomal dominant pseudohy-poaldosteronism type I. Nat Genet 19: 279 -281, 1998
16. Hummler E, Barker P, Talbot C, Wang Q, Verdumo C, Grubb B, Gatzy J, Burnier M, Horisberger JD, Beermann F, Boucher R, Rossier BC: A mouse model for the renal salt-wasting syndrome pseudohypoaldosteronism. Proc Natl Acad Sci U S A 94: 11710-11715, 1997
17. Berger S, Bleich M, Schmid W, Cole TJ, Peters J, Watanabe H, Kriz W, Warth R, Greger R, Schutz G: Mineralocorticoid receptor knockout mice: Pathophysiology of Na+ metabolism. Proc Natl Acad Sci U S A 95: 9424-9429, 1998
18. Wilson FH, Disse-Nicodeme S, Choate KA, Ishikawa K, Nelson-Williams C, Desitter I, Gunel M, Milford DV, Lipkin GW, Achard JM, Feely MP, Dussol B, Berland Y, Unwin RJ, Mayan H, Simon DB, Farfel Z, Jeunemaitre X, Lifton RP: Human hypertension caused by mutations in WNK kinases. Science 293:1107-1112, 2001
19. Subramanya AR, Yang CL, McCormick JA, Ellison DH: WNK kinases regulate sodium chloride and potassium transport by the al-dosterone-sensitive distal nephron. Kidney Int 70: 630 -634, 2006
20. Tannen RL, Wedell E, Moore R: Renal adaptation to a high potassium intake: The role of hydrogen ion. J Clin Invest 52: 2089-2101, 1973
21. Tannen RL: Relationship of renal ammonia production and potassium homeostasis. Kidney Int 11: 453-465, 1977
22. Szylman P, Better OS, Chaimowitz C, Rosler A: Role of hyperkalemia in the metabolic acidosis of isolated hypoaldosteronism. N Engl J Med 294: 361-365, 1976
23. Kurtzman NA, White MG, Rogers PW: Aldosterone deficiency and renal bicarbonate re-absorption. J Lab Clin Med 77: 931-940, 1971
24. + secretion and NH3 production in mineralocorticoid-deficient glucocorticoid-replete dogs. Am J Physiol 232: F136-F146, 1977
25. Kamm DE: Dissociation ofurine pH and NH3 excretion during KCl and NaCl loading(Abstract). Proc Annu. Meeting Am Soc Nephrol., 5th, Washington, DC, 1971, p 36.
26. DuBose TD Jr, Good DW: Effects of chronic hyperkalemia on renal production and proximal tubule transport of ammonium in rats. Am J Physiol 260: F680-F687, 1991
27. Sastrasinh S, Tannen RL: Effect of potassium on renal NH3 production. Am J Physiol 244:F383-F391, 1983
28. Kornandakieti C, Tannen RL: Hydrogen ion secretion by the distal nephron in the rat: Effect of potassium. J Lab Clin Med 104: 293-303, 1984
29. Jaeger P, Karlmark B, Giebisch G: Ammonium transport in rat cortical tubule: Relationship to potassium metabolism. Am J Physiol 245: F593-F600, 1983
30. Nagami GT: Effect of bath and luminal potassium concentration on ammonia production and secretion by mouse proximal tubules perfused in vitro. J Clin Invest 86: 3239, 1990
31. Altenberg GA: Intracellular alkalosis induced by increasing extracellular potassium: Ionic dependence and effects of amiloride and DIDS. Miner Electrolyte Metab 16: 197-201, 1990
32. Wang WH, Wang Y, Silbernagl S, Oberleithner H: Fused cells of frog proximal tubule: II. Voltage-dependent intracellular pH. J Membr Biol 101: 259-265, 1988
33. Tannen RL, McGill J: Influence of potassium on renal ammonia production. Am J Physiol 231: 1178-1184, 1976
34. + on renal slice ammoniagenesis [Abstract]. Clin Res 26: 459A, 1978
35. Sleeper RS, Belanger P, Lemieux G, Preuss HG: Effects of in vitro potassium on ammoniagenesis in rat and canine kidney tissue. Kidney Int 21: 345-353, 1982
36. Tannen RL, Kunin AS: Effect of potassium on ammoniagenesis by renal mitochondria. Am J Physiol 231: 44-51, 1976
37. Goldstein L: Relation ofglutamate to ammonia production in the rat kidney. Am J Physiol 210: 661-666, 1966
38. Simpson DP, Adam W: Glutamine transport and metabolism by mitochondria from dog renal cortex: General properties and response to acidosis and alkalosis. J Biol Chem 250: 8148-8158, 1975
39. DuBose TD Jr, Good DW: Chronic hyperkalemia impairs ammonium transport and accumulation in the inner medulla of the rat. J Clin Invest 90: 1443-1449, 1992
40. Good DW, Knepper MA, Burg MB: Ammonia and bicarbonate transport by thick ascending limb of rat kidney. Am J Physiol 247: F35-F44, 1984
41. Good DW: Ammonium transport by the thick ascending limb of Henle's loop. Annu Rev Physiol 56: 623-647, 1994
42. + transport. J Gen Physiol 103: 917-936, 1994
43. + augments net acid secretion by a ouabain-sensitive mechanism in isolated perfused inner medullary collecting ducts. Am J Physiol 270: F432-F439, 1996
44. DuBose TD Jr: Molecular and pathophysiologic mechanisms of hyperkalemic metabolic acidosis. Trans Am Clin Climatol Assoc 111: 122-133, discussion 133-124, 2000