Imaging in osteoarthritis trials: Useful or just expensive?

Nature Clinical Practice Rheumatology

Volumn 5, Issue 2, 2009, Pages 76-77

  Pelletier, Jean Pierre ^a   Martel Pelletier, Johanne ^a  

^a UNIVERSITÉ DE MONTRÉAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIINFLAMMATORY AGENT; DISEASE MODIFYING ANTIOSTEOARTHRITIS DRUG; LICOFELONE; NAPROXEN; RISEDRONIC ACID; UNCLASSIFIED DRUG;

ARTICLE; CLINICAL TRIAL; COST EFFECTIVENESS ANALYSIS; DIAGNOSTIC VALUE; DISEASE COURSE; DOSE RESPONSE; DRUG EFFICACY; DRUG MECHANISM; HUMAN; INTERMETHOD COMPARISON; JOINT CAVITY; NUCLEAR MAGNETIC RESONANCE IMAGING; OSTEOARTHRITIS; OSTEOLYSIS; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RADIODIAGNOSIS; RADIOGRAPHY; RELIABILITY; RISK FACTOR; SENSITIVITY AND SPECIFICITY;

ANTIRHEUMATIC AGENTS; DISEASE PROGRESSION; HUMANS; JOINTS; MAGNETIC RESONANCE IMAGING, INTERVENTIONAL; OSTEOARTHRITIS; TREATMENT OUTCOME;

EID: 59849129885     PISSN: 17458382     EISSN: 17458390     Source Type: Journal    
DOI: 10.1038/ncprheum0990     Document Type: Article

References (6)

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3. Brandt KD et al. (2002) Which is the best radiographic protocol for a clinical trial of a structure modifying drug in patients with knee osteoarthritis? J Rheumatol 29: 1308-1320
4. Pelletier JP et al. (2007) Risk factors associated with the loss of cartilage volume on weight-bearing areas in knee osteoarthritis patients assessed by quantitative magnetic resonance imaging: A longitudinal study. Arthritis Res Ther 9: R74
5. Bingham CO III et al. (2006) Risedronate decreases biochemical markers of cartilage degradation but does not decrease symptoms or slow radiographic progression in patients with medial compartment osteoarthritis of the knee: Results of the two-year multinational knee osteoarthritis structural arthritis study. Arthritis Rheum 54 3494-3507
6. Raynauld JP et al. (2008) Protective effects of licofelone, a 5-lipoxygenase and cyclooxygenase inhibitor, versus naproxen on cartilage loss in knee osteoarthritis: A first multi-centre clinical trial using quantitative MRI. Ann Rheum Dis [doi:10.1136/ ard.2008.088732]