Low prevalence of drug resistant HIV-1 in patients newly diagnosed with early stage of HIV infection in Korea

Tohoku Journal of Experimental Medicine

Volumn 216, Issue 3, 2008, Pages 259-265

  Kim, Chang Oh ^a   Chin, Bum Sik ^a   Han, Sang Hoon ^a   Lee, Han Sung ^a   Jeong, Su Jin ^a   Choi, Hee Kyung ^a   Choi, Jun Yong ^a   Song, Young Goo ^a   Lee, Joo Shil ^b   Kim, June Myung ^a  

^a Yonsei University College of Medicine   (South Korea)

^b Korea National Institute of Health   (South Korea)

Author keywords

Anti retroviral drugs; Genotypic drug resistance; HIV; HIV infection; Resistance mutation

Indexed keywords

ANTIRETROVIRUS AGENT; PROTEINASE; PROTEINASE INHIBITOR; RNA DIRECTED DNA POLYMERASE; RNA DIRECTED DNA POLYMERASE INHIBITOR; VIRUS RNA;

ADULT; AGED; ANTIVIRAL RESISTANCE; ARTHRALGIA; ARTICLE; CD4+ T LYMPHOCYTE; CLINICAL FEATURE; COUGHING; DIARRHEA; DISEASE COURSE; DRUG SENSITIVITY; FATIGUE; FEMALE; FEVER; GENOTYPE; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS 1 INFECTION; HUMAN IMMUNODEFICIENCY VIRUS INFECTED PATIENT; KOREA; LYMPHADENOPATHY; MAJOR CLINICAL STUDY; MALE; MYALGIA; PREVALENCE; VIRUS MUTATION; WEIGHT REDUCTION; WESTERN BLOTTING;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; DEMOGRAPHY; DRUG RESISTANCE, VIRAL; FEMALE; HIV INFECTIONS; HIV-1; HUMANS; KOREA; MALE; MIDDLE AGED; MUTATION; PREVALENCE;

EID: 59849122930     PISSN: 00408727     EISSN: 13493329     Source Type: Journal    
DOI: 10.1620/tjem.216.259     Document Type: Article

References (25)

1. Autran, B., Carcelain, G., Li, T.S., Blanc, C., Mathez, D., Tubiana, R., Katlama, C., Debre, P. & Leibowitch, J. (1997) Positive effects of combined antiretroviral therapy on CD4+ T cell homeostasis and function in advanced HIV disease. Science, 277, 112-116.
2. Balotta, C., Berlusconi, A., Pan, A., Violin, M., Riva, C. & Colombo, M.C. (2000) Prevalence of transmitted nucleoside analogue-resistant HIV-1 strains and preexisting mutations in pol reverse transcriptase and protease region: Outcome after treatment in recently infect individuals. Antiviral. Ther., 5, 7-14.
3. Boden, D., Hurley, A., Zhang, L., Cao, Y., Guo, Y. & Jones, E. (1999) HIV-1 drug resistance in newly infected individuals. JAMA, 282, 1135-1141.
4. Brambilla, D., Jennings, C., Aldrovandi, G., Bremer, J., Comeau, A.M. & Cassol, S.A. (2003) Multicenter evaluation of use of dried blood and plasma spot specimens in quantitative assays for human immunodeficiency virus RNA: measurement, precision, and RNA stability. J. Clin. Microbiol., 41, 1888-1893.
5. Chang, K.H. (2002) A study on emerging infectious diseases in Korea: Prevalence of genotypic resistance to nucleoside reverse transcriptase inhibitors and protease inhibitors in Korea. Final report. Ministry of Health and Welfare (R.O.K.), Good Health R. and D. Project, 224-234.
6. Durant, J., Clevenbergh, P., Halfon, P., Delgiudice, P., Porsin, S. & Simonet, P. (1999) Drug-resistance genotyping in HIV-1 therapy: The VIRADAPT randomised controlled trial. Lancet, 353, 2195-2199.
7. Gatanaga, H., Ibe, S., Matsuda, M., Yoshida, S., Asagi, T. & Kondo, M. (2007) Drug-resistant HIV-1 prevalence in patients newly diagnosed with HIV/AIDS in Japan. Antiviral Res., 75, 75-82.
8. Hammer, S.M., Saag, M.S., Schechter, M., Montaner, J.S., Schooley, R.T. & Jacobsen, D.M. (2006) Treatment for adult HIV infection: 2006 recommendations of the International AIDS Society-USA panel. JAMA, 296, 827-843.
9. Johnson, V.A., Brun-Vezinet, F. & Clotet, B. (2008) Update of the drug resistance mutations in HIV-1: spring 2008. Top HIV Med., 16, 62-68.
10. Kim, M.S., Shin, S.Y., Park, Y.S., Kim, Y., Ku, N.S. & Kim, J.H. (2007) Therapeutic response of HAART and analysis of related factors in Korean HIV-infected persons. Infect. Chemother., 39, 142-151
11. Kim, N.J., Choi, E.S., Kim, E.S., Lee, D.H., Choe, Y.J. & Bang, J.H. (2001) Prevalence of Zidovudine Resistant Human Immunodeficiency Virus Type 1 in Zidovudine-naive Patients. Korean J. Infect. Dis., 33, 40-45.
12. Lee, J.G. (2008) Control Guide for Korean HIV/AIDS. Korea Center for Disease Control & Prevention [homepage on the Internet]. Seoul (Korea): Available from: http://dis.cdc.go.kr/.
13. Little, S.J., Holte, S., Routy, J.P., Daar, E.S., Markowitz, M. & Collier, A.C. (2002) Antiretroviral-drug resistance among patients recently infected with HIV. N. Engl. J. Med., 347, 385-394.
14. Moss, A.R., Hahn, J. A., Perry, S., Charlebois, E.D., Guzman, D. & Clark, R.A. (2004) Adherence to highly active antiretroviral therapy in the homeless population in San Francisco: a prospective study. Clin. Infect. Dis., 39, 1190-1198.
15. Novak, R.M., Chen, L., MacArthur, R.D., Baxter, J.D., Hullslek, K.H. & Grace, P. (2005) Prevalence of antiretroviral drug resistance mutations in chronically HIV-infected, treatment-naive patients: implications for routine resistance screening before initiation of antiretroviral therapy. Clin. Infect. Dis., 40, 468-474.
16. Oh, D.G. (2007a) Antiretroviral drug resistance of HIV/AIDS patients in Korea. Korea Center for Disease Control & Prevention [homepage on the Internet]. Seoul (Korea): Available from: http://dis.cdc.go.kr/.
17. Oh, D.G. (2007b) Statistical data for patients with HIV in 2006. Korea Center for Disease Control & Prevention [homepage on Internet]. Seoul (Korea): Available from: http://dis.cdc.go.kr/.
18. Park, S.W., Kim, H.B., Choi, Y.J., Kim, N.J., Oh, M.D. & Choe, K.W. (2003) Genotypic resistance of antiretroviral drugs among drug-naïve HIV type 1 patients with the background of long-term access-easy zidovudine therapy. AIDS Res. Hum. Retroviruses, 19, 1039-1043.
19. Palella, F.J. Jr., Delaney, K.M., Moorman, A.C., Loveless, M.O., Fuhrer, J., Satten, G.A., Aschman, D.J. & Holmberg, S.D. (1998) Declining morbidity and mortality among patients with advanced human immunodeficiency virus infection. N. Engl. J. Med., 338, 853-860.
20. Sax, P.E., Islam, R., Walensky, R.P., Losina, E., Weinstein, M.C. & Goldie, S.J. (2005) Should resistance testing be performed for treatment-naive HIV-infected patients? A cost-effectiveness analysis. Clin. Infect. Dis., 41, 1316-1323.
21. Shafer, R.W., Rhee, S., Pillay, D., Miller, V., Sandstrom, P. & Schapiro, J.M. (2007) HIV-1 protease and reverse transcriptase mutations for drug resistance surveillance. AIDS, 21, 215-223.
22. Shin, Y. & Kee, M. (1998) Health care systems in transition. II. Korea, Part II. The current status of HIV-AIDS in Korea. J. Public Health Med., 20, 47-51.
23. Weinstein, M.C., Goldie, S.J., Losina, E., Cohen, C.J., Baxter, J.D. & Zhang, H. (2001) Use of genotypic resistance testing to guide HIV therapy: clinical impact and cost-effectiveness. Ann. Intern. Med., 134, 440-450.
24. Yerly, S., Vora, S., Rizzardi, P., Chave, J.P., Vernazza, P.L. & Flebb, M. (2001) Acute HIV infection: Impact on the spread of HIV and transmission of drug resistance. AIDS, 15, 2287-2292.
25. Zhong, P., Kang, L., Pan, Q., Konings, F., Burda, S. & Ma, L. (2003) Identification and distribution of HIV type 1 genetic diversity and protease inhibitor resistance-associated mutations in Shaghai, P.R. China. J. Acquir. Immune. Defic. Syndr., 34, 91-101.