The monoclonal anti-BCL10 antibody (clone 331.1) is a sensitive and specific marker of pancreatic acinar cell carcinoma and pancreatic metaplasia

Virchows Archiv

Volumn 454, Issue 2, 2009, Pages 133-142

  La Rosa, Stefano ^a   Franzi, Francesca ^b   Marchet, Silvia ^b   Finzi, Giovanna ^a   Clerici, Moira ^b   Vigetti, Davide ^b   Chiaravalli, Anna Maria ^a   Sessa, Fausto ^b,c   Capella, Carlo ^b  

^a OSPEDALE DI CIRCOLO   (Italy)

^b UNIVERSITY OF INSUBRIA   (Italy)

^c IRCCS MULTIMEDICA   (Italy)

Author keywords

Acinar cell; Acinar cell carcinoma; BCL10; Pancreas

Indexed keywords

CARBOXYLESTERASE; MONOCLONAL ANTIBODY; PANCREAS ENZYME; PANCRELIPASE; PROTEIN; PROTEIN BCL 10; TUMOR MARKER;

ACINAR CELL CARCINOMA; ADULT; ARTICLE; CANCER DIAGNOSIS; CARBOXY TERMINAL SEQUENCE; CELL DEDIFFERENTIATION; CLONE; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; ECTOPIC PANCREAS; ENDOCRINE TUMOR; ESOPHAGUS MUCOSA; FEMALE; HUMAN; HUMAN TISSUE; IMMUNOREACTIVITY; LIVER CELL CARCINOMA; MAJOR CLINICAL STUDY; MALE; METAPLASIA; PANCREAS CANCER; PRIORITY JOURNAL; SENSITIVITY AND SPECIFICITY; STOMACH ADENOCARCINOMA;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANTIBODIES, MONOCLONAL; CARBOXYLESTERASE; CARCINOMA, ACINAR CELL; HUMANS; IMMUNOHISTOCHEMISTRY; METAPLASIA; PANCREAS; PANCREATIC NEOPLASMS; SENSITIVITY AND SPECIFICITY; TUMOR MARKERS, BIOLOGICAL;

EID: 59849122361     PISSN: 09456317     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00428-008-0710-x     Document Type: Article

References (29)

1. RH Hruban MB Pitman DS Klimstra 2007
2. EE Lack 2003
3. G Klöppel 2000 Mixed exocrine-endocrine tumors of the pancreas Semin Diagn Pathol 17 104 108
4. N Ohike M Kosmahl G Klöppel 2004 Mixed acinar-endocrine carcinoma of the pancreas: a clinico-pathological study and comparison with acinar cell carcinoma Virchows Arch 445 231 235
5. M Volante L Righi S Asioli 2007 Goblet cell carcinoids and other mixed neuroendocrine/nonneuroendocrine neoplasms Virchows Arch 451 suppl 1 S61 S69
6. KD Holen DS Klimstra A Hummer 2002 Clinical characteristics and outcomes from an institutional series of acinar cell carcinoma of the pancreas and related tumors J Clin Oncol 20 4673 4678
7. T Morohoshi M Kanda A Horie 1987 Immunocytochemical markers of uncommon pancreatic tumors. Acinar cell carcinoma, pancreatoblastoma, and solid cystic (papillary-cystic) tumor Cancer 59 739 747
8. E Solcia C Capella G Klöppel 1997
9. J Carrère D Figarella-Branger F Senegas-Balas 1992 Immunohistochemical study of secretory proteins in the developing human exocrine pancreas Differentiation 51 55 60
10. D Lombardo O Guy C Figarella 1978 Purification and characterization of carboxyl ester hydrolase from human pancreatic juice Biochim Biophys Acta 527 142 149
11. H Rinderknecht 1993
12. L Nilsson J Blackberg P Carlsson 1990 cDNA cloning of human-milk bile-salt-stimulated lipase and evidence for its identity to pancreatic carboxylic ester hydrolase Eur J Biochem 192 543 550
13. DL Christie DR Cleverly CJ O'Connor 1991 Human milk bile-salt stimulated lipase. Sequence similarity with rat lysophospholipase and homology with the active site region of cholinesterases FEBS Lett 278 190 194
14. CS Wang 1988 Purification of carboxyl ester lipase from human pancreas and the amino acid sequence of the N-terminal region Biochem Biophys Res Commun 155 950 955
15. S Bernback L Blackberg O Hernell 1990 The complete digestion of human milk triacylglycerol in vitro requires gastric lipase, pancreatic colipase-dependent lipase, and bile salt-stimulated lipase J Clin Invest 85 1221 1226
16. J Brodt-Eppley P White S Jenkins 1995 Plasma cholesterol esterase level is a determinant for an atherogenic lipoprotein profile in normolipidemic human subjects Biochem Biophys Acta 1272 69 72
17. F Li DY Hui 1998 Synthesis and secretion of the pancreatic-type carboxyl ester lipase by human endothelial cells Biochem J 329 675 679
18. TG Willis DM Jadayel MQ Du 1999 BCL10 is involved in t(1;14)(p22;q32) of MALT B cell lymphoma and mutated in multiple tumor types Cell 96 35 45
19. O Basturk G Zamboni DS Klimstra 2007 Intraductal and papillary variants of acinar cell carcinomas. A new addition to the challenging differential diagnosis of intraductal neoplasms Am J Surg Pathol 31 363 370
20. S La Rosa E Rigoli S Uccella 2004 CDX2 as a marker of intestinal EC-cells and related well-differentiated endocrine tumors Virchows Arch 445 248 254
21. J Qiu DR Hendrixson EN Baker 1998 Human milk lactoferrin inactivates two putative colonization factors expressed by Haemophilus influenzae Proc Natl Acad Sci U S A 95 12641 12646
22. JD Henley WA Geary CL Jackson 1997 Dedifferentiated acinic cell carcinoma of the parotid gland: a distinct rarely described entity Hum Pathol 28 869 873
23. T Kuopio TO Ekfors V NIkkanen 1995 Acinar cell carcinoma of the pancreas. Report of three cases APMIS 103 69 78
24. NG Ordonez 2001 Pancreatic acinar cell carcinoma Adv Anat Pathol 8 144 159
25. DS Klimstra CS Heffess JE Oertel 1992 Acinar cell carcinoma of the pancreas. A clinico-pathologic study of 28 cases Am J Pathol 16 815 837
26. A Hoorens NR Lemoine E McLellan 1993 Pancreatic acinar cell carcinoma. An analysis of cell lineage markers, p53 expression, and Ki-ras mutation Am J Pathol 143 685 698
27. R Reuss S Aberle K Klingel 2006 The expression of the carboxyl ester lipase gene in pancreas and pancreatic adenocarcinomas Int J Oncol 29 649 654
28. HJ Aho B Sternby M Kallajoki 1989 Carboxyl ester lipase in human tissues and acute pancreatitis Int J Pancreatol 5 123 134
29. J Nilsson M Hellquist G Bjursell 1993 The human carboxyl ester lipase-like (CELL) gene is ubiquitously expressed and contains a hypervariable region Genomics 17 416 422