Mesenchymal stem cells in regenerative medicine: Of hopes and challenges

MedGenMed Medscape General Medicine

Volumn 11, Issue 1, 2009, Pages

  Conrad, Claudius ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

VASCULOTROPIN C;

ANGIOGENESIS; CANCER TRANSPLANTATION; CELL FUNCTION; CELL HOMING; CELL MIGRATION; EDITORIAL; GENE EXPRESSION; GENE TECHNOLOGY; LYMPHANGIOGENESIS; LYMPHATIC DRAINAGE; LYMPHEDEMA; MESENCHYMAL STEM CELL; MESENCHYMAL STEM CELL TRANSPLANTATION; REGENERATIVE MEDICINE; STEM CELL GENE THERAPY; GENE THERAPY; HUMAN; STANDARD;

GENE THERAPY; HUMANS; MESENCHYMAL STEM CELL TRANSPLANTATION; MESENCHYMAL STEM CELLS; REGENERATIVE MEDICINE;

EID: 59849120162     PISSN: 15310132     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Editorial

References (8)

1. Conrad C, Gottgens B, Kinston S, et al. GATA transcription in a small rhodamine 123(low)CD34(+) subpopulation of a peripheral blood-derived CD34(-)CD105(+) mesenchymal cell line. Exp Hematol. 2002;30:887-895.
2. Hillen F, Griffioen AW. Tumour vascularization: sprouting angiogenesis and beyond. Cancer Metastasis Rev. 2007;26:489-502.
3. He Y, Rajantie I, Ilmonen M, et al. Preexisting lymphatic endothelium but not endothelial progenitor cells are essential for tumor lymphangiogenesis and lymphatic metastasis. Cancer Res. 2004;64:3737-3740.
4. Conrad C, Niess H, Huss R, et al. Multipotent mesenchymal stem cells acquire a lymphendothelial phenotype and enhance lymphatic regeneration in vivo. Circulation. 2008 Dec 31; [Epub ahead of print].
5. Conrad C, Gupta R, Mohan H, et al. Genetically engineered stem cells for therapeutic gene delivery. Curr Gene Ther. 2007;7:249-260.
6. Kirouac DC, Zandstra PW. The systematic production of cells for cell therapies. Cell Stem Cell. 2008;3:369-381.
7. Conrad C, Huss R. Adult stem cell lines in regenerative medicine and reconstructive surgery. J Surg Res. 2005;124:201-208.
8. Waehler R, Russell SJ, Curiel DT. Engineering targeted viral vectors for gene therapy. Nat Rev Genet. 2007;8:573-587.