Prominent expression of FRS2β protein in neural cells and its association with intracellular vesicles

FEBS Letters

Volumn 583, Issue 4, 2009, Pages 807-814

  Minegishi, Yuriko ^a   Iwanari, Hiroko ^b   Mochizuki, Yasuhiro ^b   Horii, Takako ^a   Hoshino, Tomoko ^a   Kodama, Tatsuhiko ^b   Hamakubo, Takao ^b   Gotoh, Noriko ^a  

^a UNIVERSITY OF TOKYO   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

Author keywords

Brain derived neurotrophic factor; FRS2; FRS3; Intracellular transport; Lysosome; SNT

Indexed keywords

BIOLOGICAL MARKER; BRAIN DERIVED NEUROTROPHIC FACTOR; PROTEIN FRS2ALPHA; PROTEIN FRS2BETA; PROTEIN TUJ1; RECEPTOR PROTEIN; UNCLASSIFIED DRUG; FRS3 PROTEIN, MOUSE; MONOCLONAL ANTIBODY; SIGNAL TRANSDUCING ADAPTOR PROTEIN;

ANIMAL TISSUE; ARTICLE; CELL VACUOLE; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; LYSOSOME; MALE; MOUSE; NERVE CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FAMILY; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; ANIMAL; ANIMAL EMBRYO; BRAIN CORTEX; CELL CULTURE; CYTOLOGY; CYTOPLASM VESICLE; FLUORESCENT ANTIBODY TECHNIQUE; GENE EXPRESSION REGULATION; GENETICS; IN SITU HYBRIDIZATION; INSTITUTE FOR CANCER RESEARCH MOUSE; METABOLISM;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; ANTIBODIES, MONOCLONAL; CELLS, CULTURED; CEREBRAL CORTEX; CYTOPLASMIC VESICLES; EMBRYO, MAMMALIAN; FLUORESCENT ANTIBODY TECHNIQUE, DIRECT; GENE EXPRESSION REGULATION, DEVELOPMENTAL; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; MALE; MICE; MICE, INBRED ICR; NEURONS;

EID: 59849112776     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.febslet.2009.01.042     Document Type: Article

References (41)

1. Schlessinger J. Cell signaling by receptor tyrosine kinases. Cell 103 (2000) 211-225
2. Pawson T., and Scott J.D. Signaling through scaffold, anchoring, and adaptor proteins. Science 278 (1997) 2075-2080
3. Pawson T. Dynamic control of signaling by modular adaptor proteins. Curr. Opin. Cell Biol. 19 (2007) 112-116
4. Gotoh, N. and Tsuchida, N. (2008). Membrane-linked Docking Protein, Encyclopedia of Cancer, 2nd ed., Springer, Heidelberg, Germany.
5. Gotoh N. Regulation of growth factor signaling by FRS2 family docking/scaffold adaptor proteins. Cancer Sci. 99 (2008) 1319-1325
6. Eswarakumar V.P., Lax I., and Schlessinger J. Cellular signaling by fibroblast growth factor receptors. Cytokine Growth Factor Rev. 16 (2005) 139-149
7. Ong S.H., Guy G.R., Hadari Y.R., Laks S., Gotoh N., Schlessinger J., and Lax I. FRS2 proteins recruit intracellular signaling pathways by binding to diverse targets on fibroblast growth factor and nerve growth factor receptors. Mol. Cell Biol. 20 (2000) 979-989
8. Gotoh N., Laks S., Nakashima M., Lax I., and Schlessinger J. FRS2 family docking proteins with overlapping roles in activation of MAP kinase have distinct spatial-temporal patterns of expression of their transcripts. FEBS Lett. 564 (2004) 14-18
9. Dixon S.J., MacDonald J.I., Robinson K.N., Kubu C.J., and Meakin S.O. Trk receptor binding and neurotrophin/fibroblast growth factor (FGF)-dependent activation of the FGF receptor substrate (FRS)-3. Biochim. Biophys. Acta 1763 (2006) 366-380
10. Hadari Y.R., Gotoh N., Kouhara H., Lax I., and Schlessinger J. Critical role for the docking-protein FRS2alpha in FGF receptor-mediated signal transduction pathways. Proc. Natl. Acad. Sci. USA 98 (2001) 8578-8583
11. Kouhara H., Hadari Y.R., Spivak-Kroizman T., Schilling J., Bar-Sagi D., Lax I., and Schlessinger J. A lipid-anchored Grb2-binding protein that links FGF-receptor activation to the Ras/MAPK signaling pathway. Cell 89 (1997) 693-702
12. Gotoh N. Control of stemness by fibroblast growth factor signaling in stem cells and cancer stem cells. Cur. Stem Cell Res. Ther. 4 (2009) 9-15
13. Gotoh N., Ito M., Yamamoto S., Yoshino I., Song N., Wang Y., Lax I., Schlessinger J., Shibuya M., and Lang R.A. Tyrosine phosphorylation sites on FRS2alpha responsible for Shp2 recruitment are critical for induction of lens and retina. Proc. Natl. Acad. Sci. USA 101 (2004) 17144-17149
14. Gotoh N., Manova K., Tanaka S., Murohashi M., Hadari Y., Lee A., Hamada Y., Hiroe T., Ito M., Kurihara T., Nakazato H., Shibuya M., Lax I., Lacy E., and Schlessinger J. The docking protein FRS2alpha is an essential component of multiple fibroblast growth factor responses during early mouse development. Mol. Cell Biol. 25 (2005) 4105-4116
15. Yamamoto S., Yoshino I., Shimazaki T., Murohashi M., Hevner R.F., Lax I., Okano H., Shibuya M., Schlessinger J., and Gotoh N. Essential role of Shp2-binding sites on FRS2alpha for corticogenesis and for FGF2-dependent proliferation of neural progenitor cells. Proc. Natl. Acad. Sci. USA 102 (2005) 15983-15988
16. Xu H., Lee K.W., and Goldfarb M. Novel recognition motif on fibroblast growth factor receptor mediates direct association and activation of SNT adapter proteins. J. Biol. Chem. 273 (1998) 17987-17990
17. Yamada M., Suzuki K., Mizutani M., Asada A., Matozaki T., Ikeuchi T., Koizumi S., and Hatanaka H. Analysis of tyrosine phosphorylation-dependent protein-protein interactions in TrkB-mediated intracellular signaling using modified yeast two-hybrid system. J. Biochem. 130 (2001) 157-165
18. Dhalluin C., Yan K.S., Plotnikova O., Lee K.W., Zeng L., Kuti M., Mujtaba S., Goldfarb M.P., and Zhou M.M. Structural basis of SNT PTB domain interactions with distinct neurotrophic receptors. Mol. Cell 6 (2000) 921-929
19. Meakin S.O., MacDonald J.I., Gryz E.A., Kubu C.J., and Verdi J.M. The signaling adapter FRS-2 competes with Shc for binding to the nerve growth factor receptor TrkA. A model for discriminating proliferation and differentiation. J. Biol. Chem. 274 (1999) 9861-9870
20. Easton J.B., Royer A.R., and Middlemas D.S. The protein tyrosine phosphatase, Shp2, is required for the complete activation of the RAS/MAPK pathway by brain-derived neurotrophic factor. J. Neurochem. 97 (2006) 834-845
21. Harada A., Katoh H., and Negishi M. Direct interaction of Rnd1 with FRS2 beta regulates Rnd1-induced down-regulation of RhoA activity and is involved in fibroblast growth factor-induced neurite outgrowth in PC12 cells. J. Biol. Chem. 280 (2005) 18418-18424
22. Gotoh N. Feedback inhibitors of epidermal growth factor receptor signaling pathways. Int. J. Biochem. Cell Biol. 41 (2009) 511-515
23. Huang L., Watanabe M., Chikamori M., Kido Y., Yamamoto T., Shibuya M., Gotoh N., and Tsuchida N. Unique role of SNT-2/FRS2beta/FRS3 docking/adaptor protein for negative regulation in EGF receptor tyrosine kinase signaling pathways. Oncogene 25 (2006) 6457-6466
24. Wu Y., Chen Z., and Ullrich A. EGFR and FGFR signaling through FRS2 is subject to negative feedback control by ERK1/2. Biol. Chem. 384 (2003) 1215-1226
25. Yorikawa C., Takaya E., Osako Y., Tanaka R., Terasawa Y., Hamakubo T., Mochizuki Y., Iwanari H., Kodama T., Maeda T., Hitomi K., Shibata H., and Maki M. Human calpain 7/PalBH associates with a subset of ESCRT-III-related proteins in its N-terminal region and partly localizes to endocytic membrane compartments. J. Biochem. 143 (2008) 731-745
26. Tachibana M., Ueda J., Fukuda M., Takeda N., Ohta T., Iwanari H., Sakihama T., Kodama T., Hamakubo T., and Shinkai Y. Histone methyltransferases G9a and GLP form heteromeric complexes and are both crucial for methylation of euchromatin at H3-K9. Genes Dev. 19 (2005) 815-826
27. Anton E.S., Marchionni M.A., Lee K.F., and Rakic P. Role of GGF/neuregulin signaling in interactions between migrating neurons and radial glia in the developing cerebral cortex. Development 124 (1997) 3501-3510
28. Ehlers M.D. Reinsertion or degradation of AMPA receptors determined by activity-dependent endocytic sorting. Neuron 28 (2000) 511-525
29. Mizushima N., Yamamoto A., Hatano M., Kobayashi Y., Kabeya Y., Suzuki K., Tokuhisa T., Ohsumi Y., and Yoshimori T. Dissection of autophagosome formation using Apg5-deficient mouse embryonic stem cells. J. Cell Biol. 152 (2001) 657-668
30. Bosco A., and Linden R. BDNF and NT-4 differentially modulate neurite outgrowth in developing retinal ganglion cells. J. Neurosci. Res. 57 (1999) 759-769
31. Bergami M., Rimondini R., Santi S., Blum R., Gotz M., and Canossa M. Deletion of TrkB in adult progenitors alters newborn neuron integration into hippocampal circuits and increases anxiety-like behavior. Proc. Natl. Acad. Sci. USA 105 (2008) 15570-15575
32. Wilde A., Beattie E.C., Lem L., Riethof D.A., Liu S.H., Mobley W.C., Soriano P., and Brodsky F.M. EGF receptor signaling stimulates SRC kinase phosphorylation of clathrin, influencing clathrin redistribution and EGF uptake. Cell 96 (1999) 677-687
33. Schmid R.S., McGrath B., Berechid B.E., Boyles B., Marchionni M., Sestan N., and Anton E.S. Neuregulin 1-erbB2 signaling is required for the establishment of radial glia and their transformation into astrocytes in cerebral cortex. Proc. Natl. Acad. Sci. USA 100 (2003) 4251-4256
34. Lamaze C., and Schmid S.L. Recruitment of epidermal growth factor receptors into coated pits requires their activated tyrosine kinase. J. Cell Biol. 129 (1995) 47-54
35. Zhang Y., McKeehan K., Lin Y., Zhang J., and Wang F. Fibroblast growth factor receptor 1 (FGFR1) tyrosine phosphorylation regulates binding of FGFR substrate 2alpha (FRS2alpha) but not FRS2beta to the receptor. Mol. Endocrinol. 22 (2008) 167-175
36. Tamai K., Toyoshima M., Tanaka N., Yamamoto N., Owada Y., Kiyonari H., Murata K., Ueno Y., Ono M., Shimosegawa T., Yaegashi N., Watanabe M., and Sugamura K. Loss of hrs in the central nervous system causes accumulation of ubiquitinated proteins and neurodegeneration. Am. J. Pathol. 173 (2008) 1806-1817
37. 2+ influx. J. Cell Biol. 163 (2003) 385-395
38. Santi S., Cappello S., Riccio M., Bergami M., Aicardi G., Schenk U., Matteoli M., and Canossa M. Hippocampal neurons recycle BDNF for activity-dependent secretion and LTP maintenance. EMBO J. 25 (2006) 4372-4380
39. Kameda Y., Ito M., Nishimaki T., and Gotoh N. FRS2 alpha 2F/2F mice lack carotid body and exhibit abnormalities of the superior cervical sympathetic ganglion and carotid sinus nerve. Dev. Biol. 314 (2008) 236-247
40. Feng X., Jiang H., Baik J.C., Edgar C., and Eide F.F. BDNF dependence in neuroblastoma. J. Neurosci. Res. 64 (2001) 355-363
41. Wagner N., Wagner K.D., Sefton M., Rodriguez-Tebar A., and Grantyn R. An abnormal response of retinoblastoma cells (Y-79) to neurotrophins. Invest. Ophthalmol. Vis. Sci. 41 (2000) 1932-1939