Pluronic-coated carbon nanotubes do not induce degeneration of cortical neurons in vivo and in vitro

Nanomedicine: Nanotechnology, Biology, and Medicine

Volumn 5, Issue 1, 2009, Pages 96-104

  Bardi, Giuseppe ^a   Tognini, Paola ^a   Ciofani, Gianni ^b   Raffa, Vittoria ^b   Costa, Mario ^a   Pizzorusso, Tommaso ^c  

^a CNR   (Italy)

^b SCUOLA SUPERIORE SANT ANNA   (Italy)

^c UNIVERSITY OF FLORENCE   (Italy)

Author keywords

Biocompatibility; Carbon nanotubes; Neurons; Surfactant; Toxicity

Indexed keywords

BIOCOMPATIBILITY; CELL CULTURE; CELL DEATH; GENE TRANSFER; NANOCOMPOSITES; NANOTUBES; NEURONS; SURFACE ACTIVE AGENTS; TOXICITY;

APOPTOSIS; BRAIN DISEASE; CEREBRAL CORTICES; CORTICAL NEURONS; CULTURED CELLS; DISPERSION FACTORS; GENE DELIVERIES; IN-VITRO; IN-VIVO; INDUCED APOPTOSIS; NANO-DEVICES; PLURONIC; PLURONIC F-127; POTENTIAL APPLICATIONS; SURFACTANT;

CARBON NANOTUBES;

CARBON NANOFIBER; POLOXAMER; SURFACTANT;

ANIMAL CELL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BRAIN CELL; BRAIN CORTEX; CELL CULTURE; CELL LINE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; IN VITRO STUDY; IN VIVO STUDY; MATERIAL COATING; MOUSE; NERVE CELL DEGENERATION; NONHUMAN;

ANIMALS; APOPTOSIS; CELLS, CULTURED; CEREBRAL CORTEX; INJECTIONS; MICE; MICROSCOPY, FLUORESCENCE; MICROSCOPY, PHASE-CONTRAST; NANOTUBES, CARBON; NEURONS; POLOXAMER; SURFACE-ACTIVE AGENTS;

EID: 59849110117     PISSN: 15499634     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.nano.2008.06.008     Document Type: Article

References (21)

1. Iijima S. Helical microtubules of graphitic carbon. Nature 354 (1991) 56-58
2. Malarkey E.B., and Parpura V. Applications of carbon nanotubes in neurobiology. Neurodegener Dis 4 (2007) 292-299
3. Galvan-Garcia P., Keefer E.W., Yang F., Zhang M., Fang S., Zakhidov A.A., et al. Robust cell migration and neuronal growth on pristine carbon nanotube sheets and yarns. J Biomater Sci Polym Ed 18 (2007) 1245-1261
4. Jan E., and Kotov N.A. Successful differentiation of mouse neural stem cells on layer-by-layer assembled single-walled carbon nanotube composite. Nano Lett 7 (2007) 1123-1128
5. Mattson M.P., Haddon R.C., and Rao A.M. Molecular functionalization of carbon nanotubes and use as substrates for neuronal growth. J Mol Neurosci 14 (2000) 175-182
6. Mazzatenta A., Giugliano M., Campidelli S., Gambazzi L., Businaro L., Markram H., et al. Interfacing neurons with carbon nanotubes: electrical signal transfer and synaptic stimulation in cultured brain circuits. J Neurosci 27 (2007) 6931-6936
7. Lacerda L., Raffa V., Prato M., Bianco A., and Kostarelos K. Cell-penetrating carbon nanotubes in the delivery of therapeutics. Nano Today 2 (2007) 38-43
8. Lacerda L., Bianco A., Prato M., and Kostarelos K. Carbon nanotubes as nanomedicines: from toxicology to pharmacology. Adv Drug Deliv Rev 58 (2006) 1460-1470
9. Vaisman L., Wagner H., and Marom G. The role of surfactants in dispersion of carbon nanotubes. Adv Colloid Interfac 128-130 (2006) 37-46
10. Ajayan P.M., and Tour J.M. Nanotubes composites. Nature 447 (2007) 1066-1068
11. Dutta D., Sundaram S.K., Teeguarden J.G., Riley B.J., Fifield L.S., Jacobs J.M., et al. Adsorbed proteins influence the biological activity and molecular targeting of nanomaterials. Toxicol Sci 100 (2007) 303-315
12. Zhang L.W., Zeng L., Barron A.R., and Monteiro-Riviere N.A. Biological interactions of functionalized single-wall carbon nanotubes in human epidermal keratinocytes. Int J Toxicol 26 (2007) 103-113
13. Monteiro-Riviere N.A., Inman A.O., Wang Y.Y., and Nemanich R.J. Surfactant effects on carbon nanotube interactions with human keratinocytes. Nanomedicine 1 (2005) 293-299
14. Kouravelou K., Sotirchos S., and Verykios X. Catalytic effects of production of carbon nanotubes in a thermogravimetric CVD reactor. Surf Coat Technol 201 (2007) 9226-9231
15. Tasis D., Tagmatarchis N., Bianco A., and Prato M. Chemistry of carbon nanotubes. Chem Rev 106 (2006) 1105-1136
16. Li Z., Luo G., Zhou W., Wei F., Xiang R., and Liu Y. The quantitative characterization of the concentration and dispersion of multi-walled carbon nanotubes in suspension by spectrophotometry. Nanotechnology 17 (2006) 3692-3698
17. Zhang J., Zou H., Qing Q., Yang Y., Li Q., Liu Z., et al. Effect of chemical oxidation on the structure of single-walled carbon nanotubes. J Phys Chem B 107 (2003) 3712
18. Bardi G., Sengupta R., Khan M.Z., Patel J.P., and Meucci O. Human immunodeficiency virus gp120-induced apoptosis of human neuroblastoma cells in the absence of CXCR4 internalization. J Neurovirol 12 (2006) 211-218
19. Liopo A.V., Stewart M.P., Hudson J., Tour J.M., and Pappas T.C. Biocompatibility of native and functionalized single-walled carbon nanotubes for neuronal interface. J Nanosci Nanotechnol 6 (2006) 1365-1374
20. 2+ in neuronal cells. Brain Res 1068 (2006) 131-137
21. Yates S.L., Fluhler E.N., and Lippiello P.M. Advances in the use of the fluorescent probe fura-2 for the estimation of intrasynaptosomal calcium. J Neurosci Res 32 (1992) 255-260