Troponin T concentration 3 days after acute ST-elevation myocardial infarction predicts infarct size and cardiac function at 3 months

Cardiology

Volumn 113, Issue 3, 2009, Pages 207-212

  Bøhmer, Ellen ^a,b   Hoffmann, Pavel ^b   Abdelnoor, Michael ^c   Seljeflot, Ingebjørg ^b,c   Halvorsen, Sigrun ^b,c  

^a INNLANDET HOSPITAL TRUST   (Norway)

^b Department of Cardiology ^*  (Norway)

^c ULLEVÅL UNIVERSITY HOSPITAL   (Norway)

Author keywords

Acute myocardial infarction; Infarct size; Left ventricular ejection fraction; Troponin T

Indexed keywords

ANGIOTENSIN RECEPTOR ANTAGONIST; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; GADOLINIUM PENTETATE; TROPONIN T;

ACUTE HEART INFARCTION; ADULT; AGE; AGED; ARTICLE; BLOOD CLOT LYSIS; BLOOD SAMPLING; CLINICAL FEATURE; CONTROLLED STUDY; DISEASE COURSE; FEMALE; HEART FUNCTION; HEART INFARCTION; HEART INFARCTION SIZE; HEART LEFT VENTRICLE EJECTION FRACTION; HUMAN; LINEAR REGRESSION ANALYSIS; MAJOR CLINICAL STUDY; MALE; MEDICAL ASSESSMENT; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; SEX DIFFERENCE; ST SEGMENT ELEVATION;

ADULT; AGED; BIOLOGICAL MARKERS; ELECTROCARDIOGRAPHY; FEMALE; FOLLOW-UP STUDIES; HUMANS; LINEAR MODELS; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; MYOCARDIAL INFARCTION; PREDICTIVE VALUE OF TESTS; ROC CURVE; SENSITIVITY AND SPECIFICITY; SEVERITY OF ILLNESS INDEX; STROKE VOLUME; THROMBOLYTIC THERAPY; TREATMENT OUTCOME; TROPONIN T;

EID: 59849109507     PISSN: 00086312     EISSN: None     Source Type: Journal    
DOI: 10.1159/000201991     Document Type: Article

References (22)

1. Gibbons RJ, Valeti US, Araoz PA, Jaffe AS: The quantification of infarct size. J Am Coll Cardiol 2004;44:1533-1542.
2. Burns RJ, Gibbons RJ, Yi Q, Roberts RS, Miller TD, Schaer GL, Anderson JL, Yusuf S: The relationships of left ventricular ejection fraction, end-systolic volume and infarct size to six-month mortality after hospital discharge following myocardial infarction treated by thrombolysis. J Am Coll Cardiol 2002;39:30-36.
3. Herlitz J, Hjalmarson A, Waldenstrøm J: Relationship between different enzymatic estimations of the infarct size. Acta Cardiol 1985;40:217-228.
4. Miller TD, Christian TF, Hopfenspringer MR, Hodge DO, Gersh BJ, Gibbons RJ: Infarct size after acute myocardial infarction measured by quantitative tomographic 99mTc sestamibi imaging predicts subsequent mor tality. Circulation 1995;92:334-341.
5. Kan G, Visser CA, Koolen JJ, Dunning AJ: Short and long term predictive value of admission wall motion score in acute myocardial infarction. A cross-sectional echocardiographic study of 345patients. Br Heart J 1986;56:422-427.
6. Kim RJ, Wu E, Rafael A, Chen EL, Parker MA, Simonetti O, Klocke FJ, Bonow RO, Judd RM: The use of contrast-enhanced magnetic resonance imaging to identify reversible myocardial dysfunction. N Engl J Med 2000;343:1445-1453.
7. Wagner A, Mahrholdt H, Holly TA, Elliot MD, Regenfus M, Parker M, Klocke FJ, Bonow RO, Kim RJ, Judd RM: Contrast-enhanced MRI and routine single photon emission computed tomography (SPECT) perfusion imaging for detection of subendocardial myocardial infarcts: an imaging study. Lancet 2003;361:374-379.
8. Mahrholdt H, Wagner A, Holly TA, Elliot MD, Bonow RO, Kim RJ, Judd RM: Reproducibility of chronic infarct size measurements by contrast-enhanced magnetic resonance imaging. Circulation 2002;106:2322-2327.
9. Katus HA, Remppis A, Scheffold T, Diederich KW, Kuebler W: Intracellular comartmentation of cardiac troponin T and its release kinetics in patients with reperfused and non-reperfused myocardial infarction. Am J Cardiol 1991;67:1360-1367.
10. Licka M, Zimmermann R, Zehelein J, Dengler TJ, Katus HA, Kübler W: Troponin T concentrations 72h after myocardial infarction as a serological estimate of infarct size. Heart 2002;87:520-524.
11. Steen H, Giannitsis E, Futterer S, Merten C, Juenger C, Katus HA: Cardiac troponin T at 96h after acute myocardial infarction correlates with infarct size and cardiac function. J Am Coll Cardiol 2006;48:2192-2194.
12. Steen H, Futterer S, Merten C, Jünger C, Katus HA, Giannitsis E: Relative role of NT-pro BNP and cardiac troponin T at 96h for estimation of infarct size and left ventricular function after acute myocardial infarction. J Cardiovasc Magn Reson 2007;9:749-758.
13. Giannitsis E, Steen H, Kurz K, Ivandic B, Simon AC, Futterer S, Schild C, Isfort P, Jaffe AS, Katus HA: Cardiac magnetic resonance imaging study for quantification of infarct size comparing directly serial versus single time-point measurements of cardiac troponin T. J Am Coll Cardiol 2008;51:307-314.
14. Halvorsen S, Müller C, Bendz B, Eritsland J, Brekke M, Mangschau A: Left ventricular function and infarct size 20months after primary angioplasty for acute myocardial infarction. Scand Cardiovasc J 2001;35:379-384.
15. Bøhmer E, Arnesen H, Abdelnoor M, Mangschau A, Hoffmann P, Halvorsen S: The Norwegian study on district treatment of ST-elevation myocardial infarction. Scand Cardiovasc J 2007;41:32-38.
16. Sadowski EA, Bennett LK, Chan MR, Wentland AL, Garret AL, Garret RW, Djamali A: Nephrogenic systemic fibrosis: risk factors and incidence estimation. Radiology 2007;243:148-157.
17. Hoffmann P, Halvorsen S, Stensæth KH, Brekke M, Müller C, Anker GO, Abdelnoor M, Kløv NE: Myocardial perfusion in ST-elevation myocardial infarction treated successfully with primary angioplasty. Scand Cardiovasc J 2006;40:96-104.
18. The Multicenter Postinfarction Research Group: Risk stratification and survival after myocardial infarction. N Engl J Med 1983;309:331-336.
19. Fletcher RH, Fletcher SW: Clinical Epidemiology: The Essentials, ed 4. Philadelphia, Lippincott Williams &Wilkins, 2005, pp 38-50.
20. Panteg hini M, Cuccia C, Bonett i G, Giubbi ni R, Pagani F, Bonini E: Single point cardiac troponin T at coronary care unit discharge after myocardial infarction correlates with infarct size and ejection fraction. Clin Chem 2002;48:1432-1436.
21. Panteghini M, Bonetti G, Pagani F, Stefini F, Giubbini R, Cuccia C: Measurement of troponin I 48h after admission as a tool to rule out impaired left ventricular function in patients with a first myocardial infarction. Clin Chem Lab Med 2005;43:848-854.
22. Rao ACR, Collinson PO, Canepa-Anson R, Joseph SP: Troponin measurement after myocardial infarction can identify left ventricular ejection fraction of less than 40%. Heart 1998;80:223-225.