메뉴 건너뛰기




Volumn 14, Issue 33, 2008, Pages 3482-3491

Room for improvement in the pharmacological treatment of anxiety disorders

Author keywords

Anxiety disorder; CBT; Recognition; Response; SSRI; Tolerability; Treatment

Indexed keywords

AGOMELATINE; ALPRAZOLAM; BUSPIRONE; CYCLOSERINE; DULOXETINE; ESCITALOPRAM; FLUOXETINE; FLUVOXAMINE; GINKGO BILOBA EXTRACT; HERBACEOUS AGENT; IMIPRAMINE; LORAZEPAM; MOCLOBEMIDE; PAROXETINE; PHENELZINE; PINDOLOL; PLACEBO; PREGABALIN; QUETIAPINE; SEROTONIN NORADRENALIN REUPTAKE INHIBITOR; SEROTONIN UPTAKE INHIBITOR; SERTRALINE; TRIFLUOPERAZINE; VENLAFAXINE;

EID: 59849102458     PISSN: 13816128     EISSN: None     Source Type: Journal    
DOI: 10.2174/138161208786848810     Document Type: Review
Times cited : (25)

References (93)
  • 1
    • 27644534854 scopus 로고    scopus 로고
    • Evidence-based guidelines for the pharmacological treatment of anxiety disorders: Recommendations from the British association for Psychopharmacology
    • Baldwin DS, Anderson IM, Nutt DJ, Bandelow B, Bond A, Davidson J, et al. Evidence-based guidelines for the pharmacological treatment of anxiety disorders: Recommendations from the British association for Psychopharmacology. J Psychopharmacol 2005; 19: 567-96.
    • (2005) J Psychopharmacol , vol.19 , pp. 567-596
    • Baldwin, D.S.1    Anderson, I.M.2    Nutt, D.J.3    Bandelow, B.4    Bond, A.5    Davidson, J.6
  • 2
    • 0037042595 scopus 로고    scopus 로고
    • Physicians' and patients' choices in evidence based practice
    • Haynes RB, Devereaux PJ, Guyatt GH. Physicians' and patients' choices in evidence based practice. BMJ 2002; 324: 1350.
    • (2002) BMJ , vol.324 , pp. 1350
    • Haynes, R.B.1    Devereaux, P.J.2    Guyatt, G.H.3
  • 5
    • 34547469996 scopus 로고    scopus 로고
    • Post-traumatic stress disorder
    • National Institute for Clinical Excellence, number, The Royal College of Psychiatrists and the British Psychological Society: London;
    • National Institute for Clinical Excellence. Post-traumatic stress disorder. The management of PTSD in adults and children in primary and secondary care. National Clinical Practice Guideline number 26. The Royal College of Psychiatrists and the British Psychological Society: London; 2005.
    • (2005) The management of PTSD in adults and children in primary and secondary care. National Clinical Practice Guideline , vol.26
  • 6
    • 65649133716 scopus 로고    scopus 로고
    • Guy W. The clinical global impression severity and impression scales. ECDEU Assessment Manual for Psychopathology. Rockville, MD. US Dept Health: Education and Welfare 1976; 218-22.
    • Guy W. The clinical global impression severity and impression scales. ECDEU Assessment Manual for Psychopathology. Rockville, MD. US Dept Health: Education and Welfare 1976; 218-22.
  • 7
    • 34249893069 scopus 로고    scopus 로고
    • The role of pregabalin in the treatment of generalized anxiety disorder
    • Baldwin DS, Ajel K. The role of pregabalin in the treatment of generalized anxiety disorder. Neuropsychiatric Dis Treat 2007; 3: 185-91.
    • (2007) Neuropsychiatric Dis Treat , vol.3 , pp. 185-191
    • Baldwin, D.S.1    Ajel, K.2
  • 8
    • 51549099524 scopus 로고
    • The assessment of anxiety states by rating
    • Hamilton M. The assessment of anxiety states by rating. Br J Med Psychol 1959; 32: 50-55.
    • (1959) Br J Med Psychol , vol.32 , pp. 50-55
    • Hamilton, M.1
  • 9
    • 33748432736 scopus 로고    scopus 로고
    • Escitalopram and paroxetine in the treatment of generalised anxiety disorder. Randomised, double-blind, placebo-controlled study
    • Baldwin DS, Huusom AKT, Maehlum E. Escitalopram and paroxetine in the treatment of generalised anxiety disorder. Randomised, double-blind, placebo-controlled study. Br J Psychiatry 2006; 189: 264-72.
    • (2006) Br J Psychiatry , vol.189 , pp. 264-272
    • Baldwin, D.S.1    Huusom, A.K.T.2    Maehlum, E.3
  • 10
    • 33746160520 scopus 로고    scopus 로고
    • What is the threshold for symptomatic response and remission for major depressive disorder, panic disorder, social anxiety disorder, and generalized anxiety disorder?
    • Bandelow B, Baldwin DS, Dolberg OT, Andersen HF, Stein DJ. What is the threshold for symptomatic response and remission for major depressive disorder, panic disorder, social anxiety disorder, and generalized anxiety disorder? J Clin Psychiatry 2006; 67: 1428-34.
    • (2006) J Clin Psychiatry , vol.67 , pp. 1428-1434
    • Bandelow, B.1    Baldwin, D.S.2    Dolberg, O.T.3    Andersen, H.F.4    Stein, D.J.5
  • 11
    • 32244442982 scopus 로고    scopus 로고
    • Remission of generalized anxiety disorder: A review of the paroxetine clinical trials database
    • Rickels K, Rynn M, Iyengar M, Duff D. Remission of generalized anxiety disorder: A review of the paroxetine clinical trials database. J Clin Psychiatry 2006; 67: 41-7.
    • (2006) J Clin Psychiatry , vol.67 , pp. 41-47
    • Rickels, K.1    Rynn, M.2    Iyengar, M.3    Duff, D.4
  • 12
    • 35648988598 scopus 로고    scopus 로고
    • An effect-size analysis of pharmacologic treatments for generalized anxiety disorder
    • Hidalgo RB, Tupler LA, Davidson JRT. An effect-size analysis of pharmacologic treatments for generalized anxiety disorder. J Psychopharmacol 2007; 21: 864-72.
    • (2007) J Psychopharmacol , vol.21 , pp. 864-872
    • Hidalgo, R.B.1    Tupler, L.A.2    Davidson, J.R.T.3
  • 13
    • 15444365574 scopus 로고    scopus 로고
    • A meta-analytic review of the efficacy of drug treatment in generalized anxiety disorder
    • Mitte K, Noack P, Steil R, Hautzinger M. A meta-analytic review of the efficacy of drug treatment in generalized anxiety disorder. J Clin Psychopharmacol 2005; 25: 141-50.
    • (2005) J Clin Psychopharmacol , vol.25 , pp. 141-150
    • Mitte, K.1    Noack, P.2    Steil, R.3    Hautzinger, M.4
  • 14
    • 0036153311 scopus 로고    scopus 로고
    • Cognitive-behavioral therapy for social anxiety disorder: Current status and future directions
    • Heimberg RG. Cognitive-behavioral therapy for social anxiety disorder: current status and future directions. Biol Psychiatry 2002; 51: 101-08.
    • (2002) Biol Psychiatry , vol.51 , pp. 101-108
    • Heimberg, R.G.1
  • 17
    • 0032773913 scopus 로고    scopus 로고
    • Paroxetine in social phobia/social anxiety disorder. Randomised, double-blind, placebo-controlled study
    • Baldwin DS, Bobes J, Stein DJ, Scharwachter I, Faure M. Paroxetine in social phobia/social anxiety disorder. Randomised, double-blind, placebo-controlled study. Br J Psychiatr 1999; 175: 120-26.
    • (1999) Br J Psychiatr , vol.175 , pp. 120-126
    • Baldwin, D.S.1    Bobes, J.2    Stein, D.J.3    Scharwachter, I.4    Faure, M.5
  • 18
    • 3543043767 scopus 로고    scopus 로고
    • Efficacy and tolerability of escitalopram in 12- and 24-week treatment of social anxiety disorder: Randomised, double-blind, placebo-controlled, fixed-dose study
    • Lader M, Stender K, Burger V, Nil R. Efficacy and tolerability of escitalopram in 12- and 24-week treatment of social anxiety disorder: randomised, double-blind, placebo-controlled, fixed-dose study. Depress Anx 2004; 19: 241-8.
    • (2004) Depress Anx , vol.19 , pp. 241-248
    • Lader, M.1    Stender, K.2    Burger, V.3    Nil, R.4
  • 19
    • 4444333450 scopus 로고    scopus 로고
    • Efficacy of venlafaxine ER in patients with social anxiety disorder: A double-blind, placebo-controlled, parallel-group comparison with paroxetine
    • Allgulander C, Mangano R, Zhang J, Dahl AA, Lepola U, Sjödin I, et al. Efficacy of venlafaxine ER in patients with social anxiety disorder: A double-blind, placebo-controlled, parallel-group comparison with paroxetine. Hum Psychopharmacol 2004; 19: 387-96.
    • (2004) Hum Psychopharmacol , vol.19 , pp. 387-396
    • Allgulander, C.1    Mangano, R.2    Zhang, J.3    Dahl, A.A.4    Lepola, U.5    Sjödin, I.6
  • 20
    • 13244255707 scopus 로고    scopus 로고
    • Venlafaxine extended release vs placebo and paroxetine in social anxiety disorder
    • Liebowitz MR, Gelenberg AJ, Munjack D. Venlafaxine extended release vs placebo and paroxetine in social anxiety disorder. Arch Gen Psychiatry 2005; 62: 190-8.
    • (2005) Arch Gen Psychiatry , vol.62 , pp. 190-198
    • Liebowitz, M.R.1    Gelenberg, A.J.2    Munjack, D.3
  • 21
    • 0036152363 scopus 로고    scopus 로고
    • A randomized, double-blind, fixed-dose comparison of paroxetine and placebo in the treatment of generalized social anxiety disorder
    • Liebowitz MR, Stein MB, Tancer M. A randomized, double-blind, fixed-dose comparison of paroxetine and placebo in the treatment of generalized social anxiety disorder. J Clin Psychiatry 2002; 63: 66-74.
    • (2002) J Clin Psychiatry , vol.63 , pp. 66-74
    • Liebowitz, M.R.1    Stein, M.B.2    Tancer, M.3
  • 22
    • 12144285831 scopus 로고    scopus 로고
    • Efficacy of the novel anxiolytic pregabalin in social anxiety disorder: A placebo-controlled, multicenter study
    • Pande AC, Feltner DE, Jefferson JW, Davidson JR, Pollack M, Stein MB, et al. Efficacy of the novel anxiolytic pregabalin in social anxiety disorder: A placebo-controlled, multicenter study. J Clin Psychopharmacol 2004; 24: 141-9.
    • (2004) J Clin Psychopharmacol , vol.24 , pp. 141-149
    • Pande, A.C.1    Feltner, D.E.2    Jefferson, J.W.3    Davidson, J.R.4    Pollack, M.5    Stein, M.B.6
  • 23
    • 33845807475 scopus 로고    scopus 로고
    • The efficacy of selective serotonin reuptake inhibitors in adult social anxiety disorder: A meta-analysis of double-blind, placebo-controlled trials
    • Hedges DW, Brown BL, Shwalb DA, Godfrey K, Larcher AM. The efficacy of selective serotonin reuptake inhibitors in adult social anxiety disorder: A meta-analysis of double-blind, placebo-controlled trials. J Psychopharmacol 2007; 21: 102-11.
    • (2007) J Psychopharmacol , vol.21 , pp. 102-111
    • Hedges, D.W.1    Brown, B.L.2    Shwalb, D.A.3    Godfrey, K.4    Larcher, A.M.5
  • 24
    • 0033397229 scopus 로고    scopus 로고
    • Clinical guidelines for establishing remission in patients with depression and anxiety
    • Ballenger JC. Clinical guidelines for establishing remission in patients with depression and anxiety. J Clin Psychiatry 1999; 60 (Suppl 22): 29-34.
    • (1999) J Clin Psychiatry , vol.60 , Issue.SUPPL. 22 , pp. 29-34
    • Ballenger, J.C.1
  • 25
    • 12344249711 scopus 로고    scopus 로고
    • Efficacy of low and higher dose extended-release venlafaxine in generalized social anxiety disorder: A 6-month randomized controlled trial
    • Stein MB, Pollack MH, Bystritsky A, Kelsey JE, Mangano RM. Efficacy of low and higher dose extended-release venlafaxine in generalized social anxiety disorder: A 6-month randomized controlled trial. Psychopharmacology 2005; 177: 280-8.
    • (2005) Psychopharmacology , vol.177 , pp. 280-288
    • Stein, M.B.1    Pollack, M.H.2    Bystritsky, A.3    Kelsey, J.E.4    Mangano, R.M.5
  • 26
    • 7744238183 scopus 로고    scopus 로고
    • A multicenter, randomized, double-blind, placebo-controlled trial of paroxetine in children and adolescents with social anxiety disorder
    • Wagner KD, Berard R, Stein MB, Wetherhold E, Carpenter DJ, Perera P, et al. A multicenter, randomized, double-blind, placebo-controlled trial of paroxetine in children and adolescents with social anxiety disorder. Arch Gen Psychiatry 2004; 61: 1153-62.
    • (2004) Arch Gen Psychiatry , vol.61 , pp. 1153-1162
    • Wagner, K.D.1    Berard, R.2    Stein, M.B.3    Wetherhold, E.4    Carpenter, D.J.5    Perera, P.6
  • 27
    • 0036364307 scopus 로고    scopus 로고
    • Open-label evaluation of venlafaxine sustained release in outpatients with generalized anxiety disorder with comorbid depression or dysthymia: Effectiveness, tolerability and predictors of response
    • Perugi G, Frare F, Toni C, Ruffolo G, Torti C. Open-label evaluation of venlafaxine sustained release in outpatients with generalized anxiety disorder with comorbid depression or dysthymia: Effectiveness, tolerability and predictors of response. Neuropsychobiology 2002; 46: 145-9.
    • (2002) Neuropsychobiology , vol.46 , pp. 145-149
    • Perugi, G.1    Frare, F.2    Toni, C.3    Ruffolo, G.4    Torti, C.5
  • 29
    • 32944454471 scopus 로고    scopus 로고
    • Characteristics and predictors of full and partial recovery from generalized anxiety disorder in primary care patients
    • Rodriguez BF, Weisberg RB, Pagano ME, Bruce SE, Spencer MA, Culpepper L, et al. Characteristics and predictors of full and partial recovery from generalized anxiety disorder in primary care patients. J Nerv Ment Dis 2006; 194: 91-7.
    • (2006) J Nerv Ment Dis , vol.194 , pp. 91-97
    • Rodriguez, B.F.1    Weisberg, R.B.2    Pagano, M.E.3    Bruce, S.E.4    Spencer, M.A.5    Culpepper, L.6
  • 30
    • 0038045771 scopus 로고    scopus 로고
    • Predictors of outcome following venlafaxine extended-release treatment of DSM-IV generalized anxiety disorder: A pooled analysis of short-and long-term studies
    • Pollack MH, Meoni P, Otto MW, Simon N, Hackett D. Predictors of outcome following venlafaxine extended-release treatment of DSM-IV generalized anxiety disorder: A pooled analysis of short-and long-term studies. J Clin Psychopharmacol 2003; 23: 250-9.
    • (2003) J Clin Psychopharmacol , vol.23 , pp. 250-259
    • Pollack, M.H.1    Meoni, P.2    Otto, M.W.3    Simon, N.4    Hackett, D.5
  • 31
    • 33845619513 scopus 로고    scopus 로고
    • Which factors predict placebo response in anxiety disorders and major depression? An analysis of placebo-controlled studies of escitalopram
    • Stein DJ, Baldwin DS, Dolberg OT, Despiegel N, Bandelow B. Which factors predict placebo response in anxiety disorders and major depression? An analysis of placebo-controlled studies of escitalopram. J Clin Psychiatry 2006; 67: 1741-6.
    • (2006) J Clin Psychiatry , vol.67 , pp. 1741-1746
    • Stein, D.J.1    Baldwin, D.S.2    Dolberg, O.T.3    Despiegel, N.4    Bandelow, B.5
  • 32
    • 0034883568 scopus 로고    scopus 로고
    • Efficacy of venlafaxine extended release in patients with major depressive disorder and comorbid generalized anxiety disorder
    • Silverstone PH, Salinas E. Efficacy of venlafaxine extended release in patients with major depressive disorder and comorbid generalized anxiety disorder. J Clin Psychiatry 2001; 62: 523-9.
    • (2001) J Clin Psychiatry , vol.62 , pp. 523-529
    • Silverstone, P.H.1    Salinas, E.2
  • 33
    • 22044441718 scopus 로고    scopus 로고
    • Escitalopram for the treatment of GAD: Efficacy across different subgroups and outcomes
    • Stein DJ, Andersen HF, Goodman WK. Escitalopram for the treatment of GAD: Efficacy across different subgroups and outcomes. Ann Clin Psychiatry 2005; 17: 71-75.
    • (2005) Ann Clin Psychiatry , vol.17 , pp. 71-75
    • Stein, D.J.1    Andersen, H.F.2    Goodman, W.K.3
  • 34
    • 42749093852 scopus 로고    scopus 로고
    • Efficacy of pre-gabalin in depressive symptoms associated with generalized anxiety disorder: A pooled analysis of 6 studies
    • Stein DJ, Baldwin DS, Baldinetti F, Mandel F. Efficacy of pre-gabalin in depressive symptoms associated with generalized anxiety disorder: A pooled analysis of 6 studies. Eur Neuropsychopharmacol 2008; 18: 422-30.
    • (2008) Eur Neuropsychopharmacol , vol.18 , pp. 422-430
    • Stein, D.J.1    Baldwin, D.S.2    Baldinetti, F.3    Mandel, F.4
  • 35
    • 40349106455 scopus 로고    scopus 로고
    • Examination of the decline in symptoms of anxiety and depression in generalized anxiety disorder: Impact of anxiety sensitivity on response to pharmacotherapy
    • Olatunji BO, Feldman G, Smits JA, Christian KM, Zalta AK, Pollack MH, et al. Examination of the decline in symptoms of anxiety and depression in generalized anxiety disorder: Impact of anxiety sensitivity on response to pharmacotherapy. Depress Anx 2008; 25: 167-71.
    • (2008) Depress Anx , vol.25 , pp. 167-171
    • Olatunji, B.O.1    Feldman, G.2    Smits, J.A.3    Christian, K.M.4    Zalta, A.K.5    Pollack, M.H.6
  • 36
    • 0022405535 scopus 로고
    • Early treatment response in anxious outpatients treated with diazepam
    • Downing RW, Rickels K. Early treatment response in anxious outpatients treated with diazepam. Acta Psychiatr Scand 1985; 72: 522-8.
    • (1985) Acta Psychiatr Scand , vol.72 , pp. 522-528
    • Downing, R.W.1    Rickels, K.2
  • 39
    • 52449100180 scopus 로고    scopus 로고
    • Early improvement during duloxetine treatment of generalized anxiety disorder predicts response and remission at endpoint
    • E-pub ahead of print
    • Pollack MH, Kornstein SG, Spann ME, Crits-Christoph P, Raskin J, Russell JM. Early improvement during duloxetine treatment of generalized anxiety disorder predicts response and remission at endpoint. J Psychiatr Res 2008; E-pub ahead of print.
    • (2008) J Psychiatr Res
    • Pollack, M.H.1    Kornstein, S.G.2    Spann, M.E.3    Crits-Christoph, P.4    Raskin, J.5    Russell, J.M.6
  • 41
    • 0032971871 scopus 로고    scopus 로고
    • Prediction of treatment outcome in social phobia: A cross-validation
    • Scholing A, Emmelkamp PM. Prediction of treatment outcome in social phobia: A cross-validation. Behav Res Ther 1999; 37: 659-70.
    • (1999) Behav Res Ther , vol.37 , pp. 659-670
    • Scholing, A.1    Emmelkamp, P.M.2
  • 42
    • 0030594653 scopus 로고    scopus 로고
    • Responders and non-responders to drug treatment in social phobia: Differences at baseline and prediction of response
    • Slaap BR, van Vliet IM, Westenberg HG, Den Boer JA. Responders and non-responders to drug treatment in social phobia: Differences at baseline and prediction of response. J Affect Disord 1996; 39: 13-9.
    • (1996) J Affect Disord , vol.39 , pp. 13-19
    • Slaap, B.R.1    van Vliet, I.M.2    Westenberg, H.G.3    Den Boer, J.A.4
  • 43
    • 0031464343 scopus 로고    scopus 로고
    • Social phobia: Long-term treatment outcome and prediction of response - a moclobemide study
    • Versiani M, Amrein R, Montgomery SA. Social phobia: Long-term treatment outcome and prediction of response - a moclobemide study. Int Clin Psychopharmacol 1997; 12: 239-54.
    • (1997) Int Clin Psychopharmacol , vol.12 , pp. 239-254
    • Versiani, M.1    Amrein, R.2    Montgomery, S.A.3
  • 44
    • 0036182223 scopus 로고    scopus 로고
    • Predictors of response to pharmacotherapy in social anxiety disorder: An analysis of 3 placebo-controlled paroxetine trials
    • Stein DJ, Stein MB, Pitts CD, Kumar R, Hunter B. Predictors of response to pharmacotherapy in social anxiety disorder: An analysis of 3 placebo-controlled paroxetine trials. J Clin Psychiatry 2002; 63: 152-5.
    • (2002) J Clin Psychiatry , vol.63 , pp. 152-155
    • Stein, D.J.1    Stein, M.B.2    Pitts, C.D.3    Kumar, R.4    Hunter, B.5
  • 45
    • 19644370282 scopus 로고    scopus 로고
    • Influence of psychiatric comorbidity on recovery and recurrence in generalized anxiety disorder, social phobia, and panic disorder: A 12-year prospective study
    • Bruce SE, Yonkers KA, Otto MW, Eisen JL, Weisberg RB, Pagano M, et al. Influence of psychiatric comorbidity on recovery and recurrence in generalized anxiety disorder, social phobia, and panic disorder: A 12-year prospective study. Am J Psychiatry 2005; 162: 1179-87.
    • (2005) Am J Psychiatry , vol.162 , pp. 1179-1187
    • Bruce, S.E.1    Yonkers, K.A.2    Otto, M.W.3    Eisen, J.L.4    Weisberg, R.B.5    Pagano, M.6
  • 46
    • 0037460745 scopus 로고    scopus 로고
    • Relapse prevention with antidepressant drug treatment in depressive disorders: A systematic review
    • Geddes JR, Carney SM, Davies C et al. Relapse prevention with antidepressant drug treatment in depressive disorders: A systematic review. Lancet 2003; 361: 653-61.
    • (2003) Lancet , vol.361 , pp. 653-661
    • Geddes, J.R.1    Carney, S.M.2    Davies, C.3
  • 47
    • 33749009561 scopus 로고    scopus 로고
    • Clinical practice guidelines. Management of anxiety disorders
    • Canadian Psychiatric Association
    • Canadian Psychiatric Association. Clinical practice guidelines. Management of anxiety disorders. Can J Psychiatr 2006; 51: 9S-91S
    • (2006) Can J Psychiatr , vol.51
  • 48
    • 33750217338 scopus 로고    scopus 로고
    • Prevention of relapse in generalized anxiety disorder by escitalopram treatment
    • Allgulander C, Florea I, Huusom AK. Prevention of relapse in generalized anxiety disorder by escitalopram treatment. Int J Neuropsychopharmacol 2006; 9: 495-505.
    • (2006) Int J Neuropsychopharmacol , vol.9 , pp. 495-505
    • Allgulander, C.1    Florea, I.2    Huusom, A.K.3
  • 49
    • 0037362288 scopus 로고    scopus 로고
    • Efficacy and tolerability of paroxetine for the long-term treatment of generalized anxiety disorder
    • Stocchi F, Nordera G, Jokinen RH, Lepola UM, Hewett K, Bryson H, et al. Efficacy and tolerability of paroxetine for the long-term treatment of generalized anxiety disorder. J Clin Psychiatry 2003; 64: 250-8.
    • (2003) J Clin Psychiatry , vol.64 , pp. 250-258
    • Stocchi, F.1    Nordera, G.2    Jokinen, R.H.3    Lepola, U.M.4    Hewett, K.5    Bryson, H.6
  • 51
    • 48849092703 scopus 로고    scopus 로고
    • Duloxetine treatment for relapse prevention in adults with generalized anxiety disorder: A double-blind placebo-controlled trial
    • Davidson JR, Wittchen HU, Llorca PM, Erickson J, Detke M, Ball SG, et al. Duloxetine treatment for relapse prevention in adults with generalized anxiety disorder: A double-blind placebo-controlled trial. Eur Neuropsychopharmacol 2008; 18(9): 673-81.
    • (2008) Eur Neuropsychopharmacol , vol.18 , Issue.9 , pp. 673-681
    • Davidson, J.R.1    Wittchen, H.U.2    Llorca, P.M.3    Erickson, J.4    Detke, M.5    Ball, S.G.6
  • 52
    • 0036283662 scopus 로고    scopus 로고
    • Characterization of the longitudinal course of improvement in generalized anxiety disorder during long-term treatment with venlafaxine XR
    • Montgomery SA, Sheehan DV, Meoni P, Haudiquet V, Hackett D. Characterization of the longitudinal course of improvement in generalized anxiety disorder during long-term treatment with venlafaxine XR. J Psychiatr Res 2002; 36: 209-17.
    • (2002) J Psychiatr Res , vol.36 , pp. 209-217
    • Montgomery, S.A.1    Sheehan, D.V.2    Meoni, P.3    Haudiquet, V.4    Hackett, D.5
  • 55
    • 0033695675 scopus 로고    scopus 로고
    • Prevention of relapse in generalized social phobia: Results of a 24-week study in responders to 20 weeks of sertraline treatment
    • Walker JR, Van Ameringen MA, Swinson R, Bowen RC, Chokka PR, Goldner E, et al. Prevention of relapse in generalized social phobia: Results of a 24-week study in responders to 20 weeks of sertraline treatment. J Clin Psychopharmacol 2000; 20: 636-44.
    • (2000) J Clin Psychopharmacol , vol.20 , pp. 636-644
    • Walker, J.R.1    Van Ameringen, M.A.2    Swinson, R.3    Bowen, R.C.4    Chokka, P.R.5    Goldner, E.6
  • 56
    • 0036895568 scopus 로고    scopus 로고
    • Efficacy of paroxetine for relapse prevention in social anxiety disorder: A 24-week study
    • Stein DJ, Versiani M, Hair T, Kumar R. Efficacy of paroxetine for relapse prevention in social anxiety disorder: A 24-week study. Arch Gen Psychiatry 2002; 59: 1111-8.
    • (2002) Arch Gen Psychiatry , vol.59 , pp. 1111-1118
    • Stein, D.J.1    Versiani, M.2    Hair, T.3    Kumar, R.4
  • 57
    • 27544443726 scopus 로고    scopus 로고
    • A 24-week randomized, double-blind, placebo-controlled study of escitalopram for the prevention of generalized social anxiety disorder
    • Montgomery SA, Nil R, Durr-Pal N, Loft H, Boulenger JP. A 24-week randomized, double-blind, placebo-controlled study of escitalopram for the prevention of generalized social anxiety disorder. J Clin Psychiatry 2005; 66: 1270-8.
    • (2005) J Clin Psychiatry , vol.66 , pp. 1270-1278
    • Montgomery, S.A.1    Nil, R.2    Durr-Pal, N.3    Loft, H.4    Boulenger, J.P.5
  • 58
    • 0038811891 scopus 로고    scopus 로고
    • Paroxetine treatment of generalized anxiety disorder: A double-blind, placebo-controlled study
    • Rickels K, Zaninelli R, McCafferty J, Bellew K, Iyengar M, Sheehan D. Paroxetine treatment of generalized anxiety disorder: A double-blind, placebo-controlled study. Am J Psychiatry 2003; 160: 749-56.
    • (2003) Am J Psychiatry , vol.160 , pp. 749-756
    • Rickels, K.1    Zaninelli, R.2    McCafferty, J.3    Bellew, K.4    Iyengar, M.5    Sheehan, D.6
  • 59
    • 0034044185 scopus 로고    scopus 로고
    • Efficacy of extended-release venlafaxine in nondepressed outpatients with generalized anxiety disorder
    • Rickels K, Pollack MH, Sheehan DV, Haskins JT. Efficacy of extended-release venlafaxine in nondepressed outpatients with generalized anxiety disorder. Am J Psychiatry 2000; 157: 968-74.
    • (2000) Am J Psychiatry , vol.157 , pp. 968-974
    • Rickels, K.1    Pollack, M.H.2    Sheehan, D.V.3    Haskins, J.T.4
  • 60
    • 0034931866 scopus 로고    scopus 로고
    • Venlafaxine extended release (ER) in the treatment of generalised anxiety disorder: Twenty-four-week placebo-controlled dose-ranging study
    • Allgulander C, Hackett D, Salinas E. Venlafaxine extended release (ER) in the treatment of generalised anxiety disorder: Twenty-four-week placebo-controlled dose-ranging study. Br J Psychiatry 2001; 179: 15-22.
    • (2001) Br J Psychiatry , vol.179 , pp. 15-22
    • Allgulander, C.1    Hackett, D.2    Salinas, E.3
  • 61
    • 34548781289 scopus 로고    scopus 로고
    • Dose-response relationship of pregabalin in patients with generalized anxiety disorder. A pooled analysis of four placebo-controlled trials
    • Bech P. Dose-response relationship of pregabalin in patients with generalized anxiety disorder. A pooled analysis of four placebo-controlled trials. Pharmacopsychiatry 2007; 40: 163-8.
    • (2007) Pharmacopsychiatry , vol.40 , pp. 163-168
    • Bech, P.1
  • 62
    • 33750099603 scopus 로고    scopus 로고
    • Chessick CA, Allen MH, Thase M, Batista Miralha da Cunha AB, Kapczinski FF, de Lima MS, et al. Azapirones for generalized anxiety disorder. Cochrane Database Syst Rev 2006; 3: CD006115.
    • Chessick CA, Allen MH, Thase M, Batista Miralha da Cunha AB, Kapczinski FF, de Lima MS, et al. Azapirones for generalized anxiety disorder. Cochrane Database Syst Rev 2006; 3: CD006115.
  • 63
    • 0022610150 scopus 로고
    • Effective short-term treatment of generalized anxiety disorder with trifluoperazine
    • Mendels J, Krajewski TF, Huffer V et al. Effective short-term treatment of generalized anxiety disorder with trifluoperazine. J Clin Psychiatry 1986; 47: 170-4.
    • (1986) J Clin Psychiatry , vol.47 , pp. 170-174
    • Mendels, J.1    Krajewski, T.F.2    Huffer, V.3
  • 64
    • 55449093251 scopus 로고    scopus 로고
    • Results from a phase III study of once-daily extended release quetiapine fumarate (quetiapine XR) monotherapy in patients with generalised anxiety disorder
    • abstract
    • Bandelow B, Bobes J, Ahokas A, Eggens I, Liu S, Brecher M. Results from a phase III study of once-daily extended release quetiapine fumarate (quetiapine XR) monotherapy in patients with generalised anxiety disorder. Int J Psychiatry Clin Pract 2007; 11: 314-5 (abstract).
    • (2007) Int J Psychiatry Clin Pract , vol.11 , pp. 314-315
    • Bandelow, B.1    Bobes, J.2    Ahokas, A.3    Eggens, I.4    Liu, S.5    Brecher, M.6
  • 65
    • 27544471383 scopus 로고    scopus 로고
    • Adjunctive risperidone in generalized anxiety disorder: A double-blind, placebo-controlled study
    • Brawman-Mintzer O, Knapp RG, Nietert PJ. Adjunctive risperidone in generalized anxiety disorder: A double-blind, placebo-controlled study. J Clin Psychiatry 2005; 66: 1321-5.
    • (2005) J Clin Psychiatry , vol.66 , pp. 1321-1325
    • Brawman-Mintzer, O.1    Knapp, R.G.2    Nietert, P.J.3
  • 66
    • 32144450616 scopus 로고    scopus 로고
    • Olanzapine augmentation of fluoxetine for refractory generalized anxiety disorder: A placebo controlled study
    • Pollack MH, Simon NM, Fagiolini A, Pitman R, McNally RJ, Nierenberg AA, et al. Olanzapine augmentation of fluoxetine for refractory generalized anxiety disorder: A placebo controlled study. Biol Psychiatry 2006; 59: 211-5.
    • (2006) Biol Psychiatry , vol.59 , pp. 211-215
    • Pollack, M.H.1    Simon, N.M.2    Fagiolini, A.3    Pitman, R.4    McNally, R.J.5    Nierenberg, A.A.6
  • 67
    • 65649090357 scopus 로고    scopus 로고
    • Stein DJ, Ahokas A, Fabiano A. Agomelatine in generalized anxiety disorder: A randomized, placebo-controlled, study. Eur Neuropsychopharmacol 2007; 17 (Suppl 4): S509-S510.
    • Stein DJ, Ahokas A, Fabiano A. Agomelatine in generalized anxiety disorder: A randomized, placebo-controlled, study. Eur Neuropsychopharmacol 2007; 17 (Suppl 4): S509-S510.
  • 68
    • 34547467605 scopus 로고    scopus 로고
    • Meta-analysis of randomized controlled comparisons of psychopharmacological and psychological treatments for anxiety disorders
    • Bandelow B, Seidler-Brandler U, Becker A, Wedekind D, Rüther E. Meta-analysis of randomized controlled comparisons of psychopharmacological and psychological treatments for anxiety disorders. World J Biol Psychiatr 2007; 8: 175-87.
    • (2007) World J Biol Psychiatr , vol.8 , pp. 175-187
    • Bandelow, B.1    Seidler-Brandler, U.2    Becker, A.3    Wedekind, D.4    Rüther, E.5
  • 69
    • 33846866063 scopus 로고    scopus 로고
    • Ginkgo biloba special extract EGb 761 in generalized anxiety disorder and adjustment disorder with anxious mood: A randomized, double-blind, placebo-controlled trial
    • Woelk H, Arnoldt KH, Kieser M, Hoerr R. Ginkgo biloba special extract EGb 761 in generalized anxiety disorder and adjustment disorder with anxious mood: A randomized, double-blind, placebo-controlled trial. J Psychiatr Res 2007; 41: 472-80.
    • (2007) J Psychiatr Res , vol.41 , pp. 472-480
    • Woelk, H.1    Arnoldt, K.H.2    Kieser, M.3    Hoerr, R.4
  • 70
    • 34547809446 scopus 로고    scopus 로고
    • Efficacy and tolerability of a standardized herbal product from Galphimia glauca on generalized anxiety disorder. A randomized, double-blind clinical trial controlled with lorazepam
    • Herrera-Arellano A, Jiménez-Ferrer E, Zamilpa A, Morales-Valdéz M, Garcia-Valencia CE, Tortoriello J. Efficacy and tolerability of a standardized herbal product from Galphimia glauca on generalized anxiety disorder. A randomized, double-blind clinical trial controlled with lorazepam. Planta Med 2007; 73: 713-7.
    • (2007) Planta Med , vol.73 , pp. 713-717
    • Herrera-Arellano, A.1    Jiménez-Ferrer, E.2    Zamilpa, A.3    Morales-Valdéz, M.4    Garcia-Valencia, C.E.5    Tortoriello, J.6
  • 71
    • 0034946458 scopus 로고    scopus 로고
    • Randomised controlled general practice trial of sertraline, exposure therapy and combined treatment in generalised social phobia
    • Blomhoff S, Haug TT, Hellström K, Holme I, Humble M, Madsbu HP, et al. Randomised controlled general practice trial of sertraline, exposure therapy and combined treatment in generalised social phobia. Br J Psychiatry 2001; 179: 23-30.
    • (2001) Br J Psychiatry , vol.179 , pp. 23-30
    • Blomhoff, S.1    Haug, T.T.2    Hellström, K.3    Holme, I.4    Humble, M.5    Madsbu, H.P.6
  • 72
    • 0344926508 scopus 로고    scopus 로고
    • Cognitive therapy versus fluoxetine in generalized social phobia: A randomized placebo-controlled trial
    • Clark DM, Ehlers A, McManus F, Hackmann A, Fennell M, Campbell H, et al. Cognitive therapy versus fluoxetine in generalized social phobia: a randomized placebo-controlled trial. J Consult Clin Psychol 2003; 71: 1058-67.
    • (2003) J Consult Clin Psychol , vol.71 , pp. 1058-1067
    • Clark, D.M.1    Ehlers, A.2    McManus, F.3    Hackmann, A.4    Fennell, M.5    Campbell, H.6
  • 73
    • 5044229135 scopus 로고    scopus 로고
    • Fluoxetine, comprehensive cognitive behavioral therapy (CCBT) and placebo in generalized social anxiety disorder
    • Davidson JR, Foa EB, Huppert JD, Keefe FJ, Franklin ME, Compton JS, et al. Fluoxetine, comprehensive cognitive behavioral therapy (CCBT) and placebo in generalized social anxiety disorder. Arch Gen Psychiatry 2004; 61: 1005-13.
    • (2004) Arch Gen Psychiatry , vol.61 , pp. 1005-1013
    • Davidson, J.R.1    Foa, E.B.2    Huppert, J.D.3    Keefe, F.J.4    Franklin, M.E.5    Compton, J.S.6
  • 74
    • 0032794768 scopus 로고    scopus 로고
    • Venlafaxine in social phobia: A study in selective serotonin reuptake inhibitor non-responders
    • Altamura AC, Pioli R, Vitto M, Mannu P. Venlafaxine in social phobia: A study in selective serotonin reuptake inhibitor non-responders. Int Clin Psychopharmacol 1999; 14: 239-45.
    • (1999) Int Clin Psychopharmacol , vol.14 , pp. 239-245
    • Altamura, A.C.1    Pioli, R.2    Vitto, M.3    Mannu, P.4
  • 75
    • 0030575374 scopus 로고    scopus 로고
    • Buspirone augmentation of selective serotonin reuptake inhibitors (SSRIs) in social phobia
    • Van Ameringen M, Mancini C, Wilson C. Buspirone augmentation of selective serotonin reuptake inhibitors (SSRIs) in social phobia. J Affect Disord 1996; 8; 115-21.
    • (1996) J Affect Disord , vol.8 , pp. 115-121
    • Van Ameringen, M.1    Mancini, C.2    Wilson, C.3
  • 76
    • 0034805127 scopus 로고    scopus 로고
    • Pindolol potentiation of paroxetine for generalized social phobia: A double-blind, placebo-controlled, crossover study
    • Stein MB, Sareen J, Hami S, Chao J. Pindolol potentiation of paroxetine for generalized social phobia: A double-blind, placebo-controlled, crossover study. Am J Psychiatry 2001; 158: 1725-27.
    • (2001) Am J Psychiatry , vol.158 , pp. 1725-1727
    • Stein, M.B.1    Sareen, J.2    Hami, S.3    Chao, J.4
  • 79
    • 0038448311 scopus 로고    scopus 로고
    • The National Institute of Mental Health Clinical Antipsychotic Trials of Intervention Effectiveness (CATIE) project: Schizophrenia trial design and protocol development
    • Stroup TS, McEvoy JP, Swartz MS, Byerly MJ, Glick ID, Canive JM, et al. The National Institute of Mental Health Clinical Antipsychotic Trials of Intervention Effectiveness (CATIE) project: Schizophrenia trial design and protocol development. Schizophr Bull 2003; 29: 15-31.
    • (2003) Schizophr Bull , vol.29 , pp. 15-31
    • Stroup, T.S.1    McEvoy, J.P.2    Swartz, M.S.3    Byerly, M.J.4    Glick, I.D.5    Canive, J.M.6
  • 80
    • 33749321169 scopus 로고    scopus 로고
    • Randomized controlled trial of the effect on Quality of Life of second- vs first-generation antipsychotic drugs in schizophrenia: Cost Utility of the Latest Antipsychotic Drugs in Schizophrenia Study (CUtLASS 1)
    • Jones PB, Barnes TR, Davies L, Dunn G, Lloyd H, Hayhurst KP, et al. Randomized controlled trial of the effect on Quality of Life of second- vs first-generation antipsychotic drugs in schizophrenia: Cost Utility of the Latest Antipsychotic Drugs in Schizophrenia Study (CUtLASS 1). Arch Gen Psychiatry 2006; 63: 1079-87.
    • (2006) Arch Gen Psychiatry , vol.63 , pp. 1079-1087
    • Jones, P.B.1    Barnes, T.R.2    Davies, L.3    Dunn, G.4    Lloyd, H.5    Hayhurst, K.P.6
  • 81
    • 4544274763 scopus 로고    scopus 로고
    • Sexual dysfunction associated with antidepressant drugs
    • Baldwin DS. Sexual dysfunction associated with antidepressant drugs. Exp Opin Drug Safety 2004; 3: 457-470.
    • (2004) Exp Opin Drug Safety , vol.3 , pp. 457-470
    • Baldwin, D.S.1
  • 82
    • 33645243454 scopus 로고    scopus 로고
    • Resolution of sexual dysfunction during double-blind treatment of major depression with reboxetine or paroxetine
    • Baldwin DS, Bridgman K, Buis C. Resolution of sexual dysfunction during double-blind treatment of major depression with reboxetine or paroxetine. J Psychopharmacol 2006; 20: 91-6.
    • (2006) J Psychopharmacol , vol.20 , pp. 91-96
    • Baldwin, D.S.1    Bridgman, K.2    Buis, C.3
  • 83
    • 51049117224 scopus 로고    scopus 로고
    • Resolution of sexual dysfunction during acute treatment of major depression with milnacipran
    • Epub ahead of print
    • Baldwin DS, Moreno R, Briley M. Resolution of sexual dysfunction during acute treatment of major depression with milnacipran. Hum Psychopharmacol 2008; [Epub ahead of print].
    • (2008) Hum Psychopharmacol
    • Baldwin, D.S.1    Moreno, R.2    Briley, M.3
  • 84
    • 0011145384 scopus 로고    scopus 로고
    • SSRI antidepressant medications: Adverse effects and tolerability
    • Ferguson JM. SSRI antidepressant medications: Adverse effects and tolerability. Prim Care J Clin Psychiatry 2001; 3: 22-7.
    • (2001) Prim Care J Clin Psychiatry , vol.3 , pp. 22-27
    • Ferguson, J.M.1
  • 85
    • 0032364561 scopus 로고    scopus 로고
    • Rethinking side effects of the selective serotonin reuptake inhibitors: Sexual dysfunction and weight gain
    • Sussman N, Ginsberg D. Rethinking side effects of the selective serotonin reuptake inhibitors: Sexual dysfunction and weight gain. Psychiatr Ann 1998; 28: 89-97.
    • (1998) Psychiatr Ann , vol.28 , pp. 89-97
    • Sussman, N.1    Ginsberg, D.2
  • 86
    • 0027405498 scopus 로고
    • A double-blind, comparative, multicenter study comparing paroxetine with fluoxetine in depressed patients
    • De Wilde J, Spiers R, Mertens C, Bartholomé F, Schotte G, Leyman S. A double-blind, comparative, multicenter study comparing paroxetine with fluoxetine in depressed patients. Acta Psychiatr Scand 1993; 87: 141-5.
    • (1993) Acta Psychiatr Scand , vol.87 , pp. 141-145
    • De Wilde, J.1    Spiers, R.2    Mertens, C.3    Bartholomé, F.4    Schotte, G.5    Leyman, S.6
  • 87
    • 33847664253 scopus 로고    scopus 로고
    • A comparison of rates of residual insomnia symptoms following pharmacotherapy or cognitive-behavioral therapy for major depressive disorder
    • Carney CE, Segal ZV, Edinger JD, Krystal AD. A comparison of rates of residual insomnia symptoms following pharmacotherapy or cognitive-behavioral therapy for major depressive disorder. J Clin Psychiatr 2007 68: 254-260.
    • (2007) J Clin Psychiatr , vol.68 , pp. 254-260
    • Carney, C.E.1    Segal, Z.V.2    Edinger, J.D.3    Krystal, A.D.4
  • 89
    • 0037212076 scopus 로고    scopus 로고
    • Place of chronic insomnia in the course of depressive and anxiety disorders
    • Ohayon MM, Roth T. Place of chronic insomnia in the course of depressive and anxiety disorders. J Psychiatr Res 2003; 37: 9-15.
    • (2003) J Psychiatr Res , vol.37 , pp. 9-15
    • Ohayon, M.M.1    Roth, T.2
  • 91
    • 40049085254 scopus 로고    scopus 로고
    • Designing new treatments for depression and anxiety
    • Chen Z, Yang J, Tobak A. Designing new treatments for depression and anxiety. IDrugs 2008; 11(3): 189-97.
    • (2008) IDrugs , vol.11 , Issue.3 , pp. 189-197
    • Chen, Z.1    Yang, J.2    Tobak, A.3
  • 92
    • 47349125085 scopus 로고    scopus 로고
    • Potential therapeutic interest of adenosine A2A receptors in psychiatric disorders
    • Cunha RA, Ferre S, Vaugeois JM, Chen JF. Potential therapeutic interest of adenosine A2A receptors in psychiatric disorders. Curr Pharm Des 2008; 14(15): 1512-24.
    • (2008) Curr Pharm Des , vol.14 , Issue.15 , pp. 1512-1524
    • Cunha, R.A.1    Ferre, S.2    Vaugeois, J.M.3    Chen, J.F.4
  • 93
    • 47349107934 scopus 로고    scopus 로고
    • Central nervous system abnormalities in fibromyalgia and chronic fatigue syndrome: New concepts in treatment
    • Gur A, Oktayoglu P. Central nervous system abnormalities in fibromyalgia and chronic fatigue syndrome: New concepts in treatment. Curr Pharm Des 2008; 14(13): 1274-94.
    • (2008) Curr Pharm Des , vol.14 , Issue.13 , pp. 1274-1294
    • Gur, A.1    Oktayoglu, P.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.