Duration of untreated psychosis and it's effect on the symptomatic recovery in schizophrenia - Preliminary results

Neuroendocrinology Letters

Volumn 29, Issue 6, 2008, Pages 990-994

  Sarotar, Brigita Novak ^a   Pesek, Marjeta Blinc ^b   Agius, Mark ^c   Kocmur, Margareta ^d,e  

^a UNIVERSITY PSYCHIATRIC HOSPITAL   (Slovenia)

^b Psychiatric Outpatient Clinic Rudnik   (Slovenia)

^c Bedfordshire Center for Mental Health Research   (United Kingdom)

^d UNIVERSITY OF LJUBLJANA   (Slovenia)

^e NONE   (Slovenia)

Author keywords

Antipsychotic treatment; Duration of untreated psychosis; Outcome; Prodrome; Schizophrenia

Indexed keywords

ATYPICAL ANTIPSYCHOTIC AGENT; CHLORPROMAZINE; NEUROLEPTIC AGENT;

ADULT; ARTICLE; CONTROLLED STUDY; DISEASE COURSE; DISEASE DURATION; DISEASE SEVERITY; EARLY DIAGNOSIS; FEMALE; HOSPITALIZATION; HUMAN; MAJOR CLINICAL STUDY; MALE; PSYCHOSIS; RETROSPECTIVE STUDY; SCHIZOPHRENIA; THERAPY DELAY; TREATMENT OUTCOME;

EID: 59849100390     PISSN: 0172780X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (19)

1. Andreasen NC, Black DW (2001). Introductory Textbook of Psychiatry. 3rd ed. Washington: America Psychiatric Publishing.
2. Chong SA, Lee C, Bird L, Verma S (2004). A risk reduction approach for schizophrenia: the Early Psychosis Intervention Programme.Ann Acad Med Singapore. 33: 630-635. Review.
3. Crow TJ, MacMillan JF, Johnson AL, Johnstone EC (1986). A randomised controlled trial of prophylactic neuroleptic treatment. Br J Psychiatry. 148: 120-127.
4. Hafner H, Hambrecht M, Loffler W, Munk-Jorgensen P, Riecker-Rossler A (1998). Is schizophrenia a disorder of all ages? A comparison of first episode and early course across the life-cycle. Psychol Med. 28: 351-365.
5. Harrigan SM, McGorry PD, Krstev H (2003). Does treatment delay in first-episode psychosis really matter? Psychol Med. 33: 97-110.
6. Helgason L (1990). Twenty years follow-up of first psychiatric presentation for schizophrenia: what could have been prevented? Acta Psychiatr Scand. 81: 231-235.
7. Lieberman JA, Fenton WS (2000). Delayed detection of psychosis: causes, consequences and effect on public health. Am J Psychiatry. 157: 1727-1730.
8. Malla A, Payne J (2005). First-episode psychosis: psychopathology, quality of life, and functional outcome. Schizophrenia Bull. 31: 650-671.
9. Marshall M, Lewis S, Lockwood A, Drake R, Jones P, Croudace T (2005). Association between duration of untreated psychosis and outcome in cohorts of first-episode patients: a systematic review. Arch Gen Psychiatry. 62: 975-983.
10. McGlashan TH (1999). Duration of untreated psychosis in first-episode schizophrenia: marker or determinant of course? Biol Psychiatry. 46: 899-907.
11. McGlashan TH, Zipursky RB, Perkins D, Addington J, Miller T, Woods SW et al (2006). Randomized, double-blind trialof olanzapine versus placebo in patients prodromally symptomatic for psychosis. Am J Psychiatry. 163: 790-799.
12. McGorry PD, Yung AR, Phillips LJ, Yuen HP, Francey S, Cosgrave EM et al. (2002). Randomized controlled trial of interventions designed to reduce the risk of progression to first-episode psychosis in a clinical sample with subtreshold symptoms. Arch Gen Psychiatry. 59: 921-928.
13. McGorry PD, Killackey E, Yung AR (2007). Early interventions in psychotic disorders: detection and treatment of the first episode and the critical early stages. MJA. 187: s8-10.
14. Morrison AP, French P, Walford L, Lewis SW, Kilcommons A, Green J et al.(2004). Cognitive therapy for the prevention of psychosis in people at ultra-high risk. Br J Psychiatry. 185: 291-297.
15. Perkins DO, Gu H, Boteva K, Lieberman JA (2005). Relationship between duration of untreated psychosis and outcome in first-episode schizophrenia: a critical review and meta-analysis. Am J Psychiatry.162: 1785-1804.
16. Singh SP (2007). Outcome measures in early psychosis; relevance of duration of untreated psychosis. Br J Psychiatry Suppl. 50: s58-63.
17. Tulloch AD, Fearon P, David AS (2006). Social outcomes in schizophrenia: from description to action. Curr Opin Psychiatry. 19 (2): 140-144.
18. Ucok A, Polat A, Cakir S, Genc A (2006). One year outcome in first episode schizophrenia. Predictors of relapse. Eur Arch Psychiatry Clin Neurosci. 256: 37-43.
19. Yung AR, Phillips L, McGorry PD, Ward J, Donovan K, Thompson K (2002). Comprehensive Assessment of at Risk Mental States (CAARMS). Melbourne: University of Melbourne.