Flash chronopotentiometric sensing of the polyions protamine and heparin at ion-selective membranes

Analytical Biochemistry

Volumn 386, Issue 2, 2009, Pages 276-281

  Gemene, Kebede L ^a   Bakker, Eric ^a,b  

^a PURDUE UNIVERSITY   (United States)

^b CURTIN UNIVERSITY   (Australia)

Author keywords

Anticoagulant; Blood analysis; Clinical diagnostics; Heparin; Ion selective membranes; Protamine

Indexed keywords

BLOOD; ENERGY GAP; ION EXCHANGE; IONS; POLYSACCHARIDES; SODIUM CHLORIDE;

ANTICOAGULANT; BLOOD ANALYSIS; CLINICAL DIAGNOSTICS; HEPARIN; PROTAMINE;

ION SELECTIVE MEMBRANES;

HEPARIN; ION; PROTAMINE; SODIUM CHLORIDE;

ARTICLE; BLOOD SAMPLING; CHRONOPOTENTIOMETRY; CONCENTRATION (PARAMETERS); DIAGNOSTIC PROCEDURE; ELECTROCHEMISTRY; EXTRACTION; INFORMATION; ION CURRENT; ION EXCHANGE; MEMBRANE; MONITORING; POTENTIOMETRY; PRIORITY JOURNAL; TITRIMETRY;

EID: 59749091235     PISSN: 00032697     EISSN: 10960309     Source Type: Journal    
DOI: 10.1016/j.ab.2008.12.023     Document Type: Article

References (24)

1. Shvarev A., and Bakker E. Response characteristics of a reversible electrochemical sensor for the polyion protamine. Anal. Chem. 77 (2005) 5221-5228
2. Guo J., Yuan Y., and Amemiya S. Voltammetric detection of heparin at polarized blood plasma/1,2-dichloroethane interfaces. Anal. Chem. 77 (2005) 5711-5719
3. Ma S.C., Yang V.C., and Meyerhoff M.E. Heparin-responsive electrochemical sensor: a preliminary study. Anal. Chem. 64 (1992) 694-697
4. Ma S.C., Yang V.C., Fu B., and Meyerhoff M.E. Electrochemical sensor for heparin: further characterization and bioanalytical applications. Anal. Chem. 65 (1993) 2078-2084
5. Fu B., Bakker E., Yun J.H., Yang V.C., and Meyerhoff M.E. Response mechanism of polymer membrane-based potentiometric polyion sensors. Anal. Chem. 66 (1994) 2250-2259
6. Meyerhoff M.E., Yang V.C., Wahr J.A., Lee L.M., Yun J.H., Fu B., and Bakker E. Potentiometric polyion sensors: new measurement technology for monitoring blood heparin concentrations during open heart surgery. Clin. Chem. 41 (1995) 1355-1356
7. Yun J.H., Meyerhoff M.E., and Yang V.C. Protamine-sensitive polymer membrane electrode: characterization and bioanalytical application. Anal. Biochem. 224 (1995) 212-220
8. Ramamurthy N., Baliga N., Wahr J.A., Schaller U., Yang V.C., and Meyerhoff M.E. Improved protamine-sensitive membrane electrode for monitoring heparin concentration in whole blood via protamine titration. Clin. Chem. 44 (1998) 606-613
9. Amemiya S., Yang X., and Wazenegger T.L. Voltammetry of the phase transfer of polypeptide protamines across polarized liquid/liquid interface. J. Am. Chem. Soc. 125 (2003) 11832-11833
10. Langmaier J., Olsak J., Samcova E., Samec Z., and Trojanek A. Amperometry of heparin polyion using a rotating disk electrode coated with a plasticized PVC membrane. Electroanalysis 18 (2006) 115-120
11. Langmaier J., Olsak J., Samcova E., Samec Z., and Trojanek A. Amperometric sensor for heparin: sensing mechanism and application in human blood plasma analysis. Electroanalysis 18 (2006) 1329-1338
12. Rodgers P.J., Jing P., Kim Y., and Amemiya S. Electrochemical recognition of synthetic heparin mimetic at liquid/liquid microinterface. J. Am. Chem. Soc. 130 (2008) 7436-7442
13. Langmaier J., Samcova E., and Samec Z. Potentiometric sensor for heparin polyion: transient behavior and response mechanism. Anal. Chem. 79 (2007) 2892-2900
14. Rodgers P.J., and Amemiya S. Cyclic voltammetry at micropipet electrodes for the study of ion-transfer kinetics at liquid/liquid interfaces. Anal. Chem. 79 (2007) 9276-9285
15. Guo J., and Amemiya S. Voltammetric heparin-selective electrode based on thin liquid membrane with conducting polymer-modified solid support. Anal. Chem. 78 (2006) 6893-6902
16. Jadhav S., and Bakker E. Voltammetric and amperometric transduction for solvent polymeric membrane ion sensors. Anal. Chem. 71 (1999) 3657-3664
17. Jadhav S., Meir A.J., and Bakker E. Normal pulse voltammetry as improved quantitative detection mode for amperometric solvent polymeric membrane ion sensors. Electroanalysis 12 (2000) 1251-1257
18. Shvarev A., and Bakker E. Pulsed galvanostatic control of ionophore-based polymeric ion sensors. Anal. Chem. 75 (2003) 4541-4550
19. Shvarev A., and Bakker E. Reversible electrochemical detection of nonelectroactive polyions. J. Am. Chem. Soc. 125 (2003) 11192-11193
20. Xu Y., Shvarev A., Makarychev-Mikhailov S., and Bakker E. Reversible detection of proteases and their inhibitors by a pulsed chronopotentiometric polyion-sensitive electrode. Anal. Biochem. 374 (2008) 366-370
21. Fordyce K., and Shvarev A. Solid-contact electrochemical polyion sensors for monitoring peptidase activities. Anal. Chem. 80 (2008) 827-833
22. Gemene K.L., and Bakker E. Direct sensing of total acidity by chronopotentiometric flash titrations at polymer membrane ion-selective electrodes. Anal. Chem. 80 (2008) 3743-3750
23. K.L. Gemene, E. Bakker, Direct measurement of total calcium in physiological fluids by flash chronopotentiometry at polymer membrane ion-selective electrodes, Submitted.
24. Guerrini M., Beccati D., Shriver Z., Naggi A., Viswanathan K., Bisio A., Capila I., Lansing J.C., Guglieri S., Fraser B., Al-Hakim A., Gunay N.S., Zhang Z., Robinson L., Buhse L., Nasr M., Woodcock J., Langer R., Venkataraman G., Linhardt R.J., Casu B., Torri G., and Sasisekharan R. Oversulfated chondroitin sulfate is a contaminant in heparin associated with adverse clinical events. Nat. Biotechnol. 26 (2008) 669-675