An inactivating mutation within the first extracellular loop of the thyrotropin receptor impedes normal posttranslational maturation of the extracellular domain

Endocrinology

Volumn 150, Issue 2, 2009, Pages 1043-1050

  Sura Trueba, Sylvia ^a,c,d   Aumas, Chantal ^a,c,d   Carre, Aurore ^c,d   Durif, Sylvie ^b   Leger, Juliane ^a   Polak, Michel ^c,d,e   De Roux, Nicolas ^a,e  

^a HÔPITAL ROBERT DEBRÉ   (France)

^b CENTRE HOSPITALIER LYON SUD   (France)

^c INSERM   (France)

^d HÔPITAL NECKER ENFANTS MALADES   (France)

^e UNIVERSITÉ PARIS DESCARTES   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ADENYLATE CYCLASE; CYCLIC AMP; IODINE 123; MANNOSE; MEMBRANE PROTEIN; THYROTROPIN; THYROTROPIN RECEPTOR;

ARTICLE; BINDING AFFINITY; CASE REPORT; CELL MATURATION; CELL MIGRATION; CONTROLLED STUDY; ENDOPLASMIC RETICULUM; GENE MUTATION; GLYCOSYLATION; GOLGI COMPLEX; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DOMAIN; PROTEIN EXPRESSION; RNA TRANSLATION; STIMULATION;

ADULT; AMINO ACID SEQUENCE; BASE SEQUENCE; CELLS, CULTURED; DNA MUTATIONAL ANALYSIS; FAMILY; FEMALE; HUMANS; INFANT, NEWBORN; MALE; MOLECULAR SEQUENCE DATA; MUTATION, MISSENSE; PEDIGREE; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, THYROTROPIN; SEQUENCE HOMOLOGY, AMINO ACID;

EID: 59649103480     PISSN: 00137227     EISSN: 00137227     Source Type: Journal    
DOI: 10.1210/en.2008-1145     Document Type: Article

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