-
1
-
-
33645089926
-
A role for beta-melanocyte-stimulating hormone in human body-weight regulation
-
Biebermann H., Castaneda T.R., van Landeghem F., von Deimling A., Escher F., Brabant G., Hebebrand J., Hinney A., Tschop M.H., Gruters A., and Krude H. A role for beta-melanocyte-stimulating hormone in human body-weight regulation. Cell Metab. 3 (2006) 141-146
-
(2006)
Cell Metab.
, vol.3
, pp. 141-146
-
-
Biebermann, H.1
Castaneda, T.R.2
van Landeghem, F.3
von Deimling, A.4
Escher, F.5
Brabant, G.6
Hebebrand, J.7
Hinney, A.8
Tschop, M.H.9
Gruters, A.10
Krude, H.11
-
2
-
-
34147119799
-
The hormonal control of food intake
-
Coll A.P., Farooqi I.S., and O'Rahilly S. The hormonal control of food intake. Cell 129 (2007) 251-262
-
(2007)
Cell
, vol.129
, pp. 251-262
-
-
Coll, A.P.1
Farooqi, I.S.2
O'Rahilly, S.3
-
3
-
-
12144291698
-
Mice lacking pro-opiomelanocortin are sensitive to high-fat feeding but respond normally to the acute anorectic effects of peptide-YY(3-36)
-
Challis B.G., Coll A.P., Yeo G.S., Pinnock S.B., Dickson S.L., Thresher R.R., Dixon J., Zahn D., Rochford J.J., White A., Oliver R.L., Millington G., Aparicio S.A., Colledge W.H., Russ A.P., Carlton M.B., and O'Rahilly S. Mice lacking pro-opiomelanocortin are sensitive to high-fat feeding but respond normally to the acute anorectic effects of peptide-YY(3-36). Proc. Natl. Acad. Sci. U.S.A. 101 (2004) 4695-4700
-
(2004)
Proc. Natl. Acad. Sci. U.S.A.
, vol.101
, pp. 4695-4700
-
-
Challis, B.G.1
Coll, A.P.2
Yeo, G.S.3
Pinnock, S.B.4
Dickson, S.L.5
Thresher, R.R.6
Dixon, J.7
Zahn, D.8
Rochford, J.J.9
White, A.10
Oliver, R.L.11
Millington, G.12
Aparicio, S.A.13
Colledge, W.H.14
Russ, A.P.15
Carlton, M.B.16
O'Rahilly, S.17
-
4
-
-
36749008499
-
A-defensin mutation causes black coat color in domestic dogs
-
Candille S.I., Kaelin C.B., Cattanach B.M., Yu B., Thompson D.A., Nix M.A., Kerns J.A., Schmutz S.M., Millhauser G.L., and Barsh G.S. A-defensin mutation causes black coat color in domestic dogs. Science 318 (2007) 1418-1423
-
(2007)
Science
, vol.318
, pp. 1418-1423
-
-
Candille, S.I.1
Kaelin, C.B.2
Cattanach, B.M.3
Yu, B.4
Thompson, D.A.5
Nix, M.A.6
Kerns, J.A.7
Schmutz, S.M.8
Millhauser, G.L.9
Barsh, G.S.10
-
5
-
-
0021912773
-
Selective attenuation of sweetened milk consumption by opiate receptor antagonists in male and female rats of the Roman strains
-
Cooper S.J., Barber D.J., and Barbour-McMullen J. Selective attenuation of sweetened milk consumption by opiate receptor antagonists in male and female rats of the Roman strains. Neuropeptides 5 (1985) 349-352
-
(1985)
Neuropeptides
, vol.5
, pp. 349-352
-
-
Cooper, S.J.1
Barber, D.J.2
Barbour-McMullen, J.3
-
6
-
-
16544371717
-
Quantitative trait locus determining dietary macronutrient intakes is located on human chromosome 2p22
-
Cai G., Cole S.A., Bastarrachea-Sosa R.A., Maccluer J.W., Blangero J., and Comuzzie A.G. Quantitative trait locus determining dietary macronutrient intakes is located on human chromosome 2p22. Am. J. Clin. Nutr. 80 (2004) 1410-1414
-
(2004)
Am. J. Clin. Nutr.
, vol.80
, pp. 1410-1414
-
-
Cai, G.1
Cole, S.A.2
Bastarrachea-Sosa, R.A.3
Maccluer, J.W.4
Blangero, J.5
Comuzzie, A.G.6
-
7
-
-
0031017322
-
A major quantitative trait locus determining serum leptin levels and fat mass is located on human chromosome 2
-
Comuzzie A.G., Hixson J.E., Almasy L., Mitchell B.D., Mahaney M.C., Dyer T.D., Stern M.P., MacCluer J.W., and Blangero J. A major quantitative trait locus determining serum leptin levels and fat mass is located on human chromosome 2. Nat. Genet. 15 (1997) 273-276
-
(1997)
Nat. Genet.
, vol.15
, pp. 273-276
-
-
Comuzzie, A.G.1
Hixson, J.E.2
Almasy, L.3
Mitchell, B.D.4
Mahaney, M.C.5
Dyer, T.D.6
Stern, M.P.7
MacCluer, J.W.8
Blangero, J.9
-
8
-
-
23644453797
-
Proopiomelanocortin-deficient mice are hypersensitive to the adverse metabolic effects of glucocorticoids
-
Coll A.P., Challis B.G., Lopez M., Piper S., Yeo G.S., and O'Rahilly S. Proopiomelanocortin-deficient mice are hypersensitive to the adverse metabolic effects of glucocorticoids. Diabetes 54 (2005) 2269-2276
-
(2005)
Diabetes
, vol.54
, pp. 2269-2276
-
-
Coll, A.P.1
Challis, B.G.2
Lopez, M.3
Piper, S.4
Yeo, G.S.5
O'Rahilly, S.6
-
9
-
-
0344412862
-
Adrenalectomy alters the sensitivity of the central nervous system melanocortin system
-
Drazen D.L., Wortman M.D., Schwartz M.W., Clegg D.J., van Dijk G., Woods S.C., and Seeley R.J. Adrenalectomy alters the sensitivity of the central nervous system melanocortin system. Diabetes 52 (2003) 2928-2934
-
(2003)
Diabetes
, vol.52
, pp. 2928-2934
-
-
Drazen, D.L.1
Wortman, M.D.2
Schwartz, M.W.3
Clegg, D.J.4
van Dijk, G.5
Woods, S.C.6
Seeley, R.J.7
-
10
-
-
33750592655
-
Heterozygosity for a POMC-null mutation and increased obesity risk in humans
-
Farooqi I.S., Drop S., Clements A., Keogh J.M., Biernacka J., Lowenbein S., Challis B.G., and O'Rahilly S. Heterozygosity for a POMC-null mutation and increased obesity risk in humans. Diabetes 55 (2006) 2549-2553
-
(2006)
Diabetes
, vol.55
, pp. 2549-2553
-
-
Farooqi, I.S.1
Drop, S.2
Clements, A.3
Keogh, J.M.4
Biernacka, J.5
Lowenbein, S.6
Challis, B.G.7
O'Rahilly, S.8
-
11
-
-
0035007332
-
Opioid receptor involvement in the effect of AgRP-(83-132) on food intake and food selection
-
Hagan M.M., Rushing P.A., Benoit S.C., Woods S.C., and Seeley R.J. Opioid receptor involvement in the effect of AgRP-(83-132) on food intake and food selection. Am. J. Physiol. Regul. Integr. Comp. Physiol. 280 (2001) R814-R821
-
(2001)
Am. J. Physiol. Regul. Integr. Comp. Physiol.
, vol.280
-
-
Hagan, M.M.1
Rushing, P.A.2
Benoit, S.C.3
Woods, S.C.4
Seeley, R.J.5
-
12
-
-
0033305324
-
Normal variation in leptin levels in associated with polymorphisms in the proopiomelanocortin gene POMC
-
Hixson J.E., Almasy L., Cole S., Birnbaum S., Mitchell B.D., Mahaney M.C., Stern M.P., MacCluer J.W., Blangero J., and Comuzzie A.G. Normal variation in leptin levels in associated with polymorphisms in the proopiomelanocortin gene POMC. J. Clin. Endocrinol. Metab. 84 (1999) 3187-3191
-
(1999)
J. Clin. Endocrinol. Metab.
, vol.84
, pp. 3187-3191
-
-
Hixson, J.E.1
Almasy, L.2
Cole, S.3
Birnbaum, S.4
Mitchell, B.D.5
Mahaney, M.C.6
Stern, M.P.7
MacCluer, J.W.8
Blangero, J.9
Comuzzie, A.G.10
-
13
-
-
0035810771
-
Agouti-related protein functions as an inverse agonist at a constitutively active brain melanocortin-4 receptor
-
Haskell-Luevano C., and Monck E.K. Agouti-related protein functions as an inverse agonist at a constitutively active brain melanocortin-4 receptor. Regul. Pept. 99 (2001) 1-7
-
(2001)
Regul. Pept.
, vol.99
, pp. 1-7
-
-
Haskell-Luevano, C.1
Monck, E.K.2
-
14
-
-
0031838353
-
Severe early-onset obesity, adrenal insufficiency and red hair pigmentation caused by POMC mutations in humans
-
Krude H., Biebermann H., Luck W., Horn R., Brabant G., and Gruters A. Severe early-onset obesity, adrenal insufficiency and red hair pigmentation caused by POMC mutations in humans. Nat. Genet. 19 (1998) 155-157
-
(1998)
Nat. Genet.
, vol.19
, pp. 155-157
-
-
Krude, H.1
Biebermann, H.2
Luck, W.3
Horn, R.4
Brabant, G.5
Gruters, A.6
-
15
-
-
0242320429
-
Obesity due to proopiomelanocortin deficiency: three new cases and treatment trials with thyroid hormone and ACTH4-10
-
Krude H., Biebermann H., Schnabel D., Tansek M.Z., Theunissen P., Mullis P.E., and Gruters A. Obesity due to proopiomelanocortin deficiency: three new cases and treatment trials with thyroid hormone and ACTH4-10. J. Clin. Endocrinol. Metab. 88 (2003) 4633-4640
-
(2003)
J. Clin. Endocrinol. Metab.
, vol.88
, pp. 4633-4640
-
-
Krude, H.1
Biebermann, H.2
Schnabel, D.3
Tansek, M.Z.4
Theunissen, P.5
Mullis, P.E.6
Gruters, A.7
-
16
-
-
0032732457
-
Macronutrient diet intake of the lethal yellow agouti (Ay/a) mouse
-
Koegler F.H., Schaffhauser R.O., Mynatt R.L., York D.A., and Bray G.A. Macronutrient diet intake of the lethal yellow agouti (Ay/a) mouse. Physiol. Behav. 67 (1999) 809-812
-
(1999)
Physiol. Behav.
, vol.67
, pp. 809-812
-
-
Koegler, F.H.1
Schaffhauser, R.O.2
Mynatt, R.L.3
York, D.A.4
Bray, G.A.5
-
17
-
-
33645048441
-
A POMC variant implicates beta-melanocyte-stimulating hormone in the control of human energy balance
-
Lee Y.S., Challis B.G., Thompson D.A., Yeo G.S., Keogh J.M., Madonna M.E., Wraight V., Sims M., Vatin V., Meyre D., Shield J., Burren C., Ibrahim Z., Cheetham T., Swift P., Blackwood A., Hung C.C., Wareham N.J., Froguel P., Millhauser G.L., O'Rahilly S., and Farooqi I.S. A POMC variant implicates beta-melanocyte-stimulating hormone in the control of human energy balance. Cell Metab. 3 (2006) 135-140
-
(2006)
Cell Metab.
, vol.3
, pp. 135-140
-
-
Lee, Y.S.1
Challis, B.G.2
Thompson, D.A.3
Yeo, G.S.4
Keogh, J.M.5
Madonna, M.E.6
Wraight, V.7
Sims, M.8
Vatin, V.9
Meyre, D.10
Shield, J.11
Burren, C.12
Ibrahim, Z.13
Cheetham, T.14
Swift, P.15
Blackwood, A.16
Hung, C.C.17
Wareham, N.J.18
Froguel, P.19
Millhauser, G.L.20
O'Rahilly, S.21
Farooqi, I.S.22
more..
-
18
-
-
0033761530
-
Adrenalectomy reverses obese phenotype and restores hypothalamic melanocortin tone in leptin-deficient ob/ob mice
-
Makimura H., Mizuno T.M., Roberts J., Silverstein J., Beasley J., and Mobbs C.V. Adrenalectomy reverses obese phenotype and restores hypothalamic melanocortin tone in leptin-deficient ob/ob mice. Diabetes 49 (2000) 1917-1923
-
(2000)
Diabetes
, vol.49
, pp. 1917-1923
-
-
Makimura, H.1
Mizuno, T.M.2
Roberts, J.3
Silverstein, J.4
Beasley, J.5
Mobbs, C.V.6
-
19
-
-
34547550573
-
Peripheral mechanisms contributing to the glucocorticoid hypersensitivity in proopiomelanocortin null mice treated with corticosterone
-
Michailidou Z., Coll A.P., Kenyon C.J., Morton N.M., O'Rahilly S., Seckl J.R., and Chapman K.E. Peripheral mechanisms contributing to the glucocorticoid hypersensitivity in proopiomelanocortin null mice treated with corticosterone. J. Endocrinol. 194 (2007) 161-170
-
(2007)
J. Endocrinol.
, vol.194
, pp. 161-170
-
-
Michailidou, Z.1
Coll, A.P.2
Kenyon, C.J.3
Morton, N.M.4
O'Rahilly, S.5
Seckl, J.R.6
Chapman, K.E.7
-
20
-
-
0035130843
-
AgRP(83-132) acts as an inverse agonist on the human-melanocortin-4 receptor
-
Nijenhuis W.A., Oosterom J., and Adan R.A. AgRP(83-132) acts as an inverse agonist on the human-melanocortin-4 receptor. Mol. Endocrinol. 15 (2001) 164-171
-
(2001)
Mol. Endocrinol.
, vol.15
, pp. 164-171
-
-
Nijenhuis, W.A.1
Oosterom, J.2
Adan, R.A.3
-
21
-
-
32444449631
-
Glucocorticoids exacerbate obesity and insulin resistance in neuron-specific proopiomelanocortin-deficient mice
-
Smart J.L., Tolle V., and Low M.J. Glucocorticoids exacerbate obesity and insulin resistance in neuron-specific proopiomelanocortin-deficient mice. J. Clin. Invest. 116 (2006) 495-505
-
(2006)
J. Clin. Invest.
, vol.116
, pp. 495-505
-
-
Smart, J.L.1
Tolle, V.2
Low, M.J.3
-
22
-
-
0037447798
-
The melanocortin receptor MCR4 controls fat consumption
-
Samama P., Rumennik L., and Grippo J.F. The melanocortin receptor MCR4 controls fat consumption. Regul. Pept. 113 (2003) 85-88
-
(2003)
Regul. Pept.
, vol.113
, pp. 85-88
-
-
Samama, P.1
Rumennik, L.2
Grippo, J.F.3
-
23
-
-
0029976448
-
Regulation of expression of ob mRNA and protein by glucocorticoids and cAMP
-
Slieker L.J., Sloop K.W., Surface P.L., Kriauciunas A., LaQuier F., Manetta J., Bue-Valleskey J., and Stephens T.W. Regulation of expression of ob mRNA and protein by glucocorticoids and cAMP. J. Biol. Chem. 271 (1996) 5301-5304
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 5301-5304
-
-
Slieker, L.J.1
Sloop, K.W.2
Surface, P.L.3
Kriauciunas, A.4
LaQuier, F.5
Manetta, J.6
Bue-Valleskey, J.7
Stephens, T.W.8
-
24
-
-
0037713246
-
Lack of proopiomelanocortin peptides results in obesity and defective adrenal function but normal melanocyte pigmentation in the murine C57BL/6 genetic background
-
Smart J.L., and Low M.J. Lack of proopiomelanocortin peptides results in obesity and defective adrenal function but normal melanocyte pigmentation in the murine C57BL/6 genetic background. Ann. N Y Acad. Sci. 994 (2003) 202-210
-
(2003)
Ann. N Y Acad. Sci.
, vol.994
, pp. 202-210
-
-
Smart, J.L.1
Low, M.J.2
-
25
-
-
35548945028
-
Pro-opiomelanocortin modulates the thermogenic and physical activity responses to high-fat feeding and markedly influences dietary fat preference
-
Tung Y.C., Rimmington D., O'Rahilly S., and Coll A.P. Pro-opiomelanocortin modulates the thermogenic and physical activity responses to high-fat feeding and markedly influences dietary fat preference. Endocrinology 148 (2007) 5331-5338
-
(2007)
Endocrinology
, vol.148
, pp. 5331-5338
-
-
Tung, Y.C.1
Rimmington, D.2
O'Rahilly, S.3
Coll, A.P.4
-
26
-
-
33751548654
-
A comparative study of the central effects of specific proopiomelancortin (POMC)-derived melanocortin peptides on food intake and body weight in pomc null mice
-
Tung Y.C., Piper S.J., Yeung D., O'Rahilly S., and Coll A.P. A comparative study of the central effects of specific proopiomelancortin (POMC)-derived melanocortin peptides on food intake and body weight in pomc null mice. Endocrinology 147 (2006) 5940-5947
-
(2006)
Endocrinology
, vol.147
, pp. 5940-5947
-
-
Tung, Y.C.1
Piper, S.J.2
Yeung, D.3
O'Rahilly, S.4
Coll, A.P.5
-
27
-
-
0032863468
-
Obesity in the mouse model of pro-opiomelanocortin deficiency responds to peripheral melanocortin
-
Yaswen L., Diehl N., Brennan M.B., and Hochgeschwender U. Obesity in the mouse model of pro-opiomelanocortin deficiency responds to peripheral melanocortin. Nat. Med. 5 (1999) 1066-1070
-
(1999)
Nat. Med.
, vol.5
, pp. 1066-1070
-
-
Yaswen, L.1
Diehl, N.2
Brennan, M.B.3
Hochgeschwender, U.4
-
28
-
-
29144519352
-
Effects of hypothalamic neurodegeneration on energy balance
-
Xu A.W., Kaelin C.B., Morton G.J., Ogimoto K., Stanhope K., Graham J., Baskin D.G., Havel P., Schwartz M.W., and Barsh G.S. Effects of hypothalamic neurodegeneration on energy balance. PLoS Biol. 3 (2005) e415
-
(2005)
PLoS Biol.
, vol.3
-
-
Xu, A.W.1
Kaelin, C.B.2
Morton, G.J.3
Ogimoto, K.4
Stanhope, K.5
Graham, J.6
Baskin, D.G.7
Havel, P.8
Schwartz, M.W.9
Barsh, G.S.10
|