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Volumn 17, Issue 10, 2008, Pages 916-921

Some antiphospholipid antibodies bind to hemostasis and fibrinolysis proteases and promote thrombosis

Author keywords

Antiphospholipid antibodies; Coagulation; Fibrinolysis; Serine protease

Indexed keywords

ACTIVATED PROTEIN C; AUTOANTIBODY; AUTOANTIGEN; BETA2 GLYCOPROTEIN 1; BLOOD CLOTTING FACTOR 10; BLOOD CLOTTING FACTOR 10A; BLOOD CLOTTING FACTOR 5A; BLOOD CLOTTING FACTOR 8A; EPITOPE; IMMUNOGLOBULIN G; MONOCLONAL ANTIBODY; PHOSPHOLIPID ANTIBODY; PLASMIN; PROTEINASE; SERINE PROTEINASE; THROMBIN; TISSUE PLASMINOGEN ACTIVATOR; BLOOD CLOTTING FACTOR; PHOSPHOLIPID;

EID: 59649091253     PISSN: 09612033     EISSN: None     Source Type: Journal    
DOI: 10.1177/0961203308092805     Document Type: Review
Times cited : (9)

References (49)
  • 1
    • 0242585716 scopus 로고    scopus 로고
    • Blood Coagulation
    • Dahlback B. Blood Coagulation. Lancet 2000; 355: 1627-1632.
    • (2000) Lancet , vol.355 , pp. 1627-1632
    • Dahlback, B.1
  • 2
    • 0034615559 scopus 로고    scopus 로고
    • Regulation of Blood Coagulation
    • Esmon CT. Regulation of Blood Coagulation. Biochim Biophys Acta 2000; 1477: 349-360.
    • (2000) Biochim Biophys Acta , vol.1477 , pp. 349-360
    • Esmon, C.T.1
  • 4
    • 0031801933 scopus 로고    scopus 로고
    • Syndromes of Thrombosis and Hypercoagulability: Congenital and Acquired Causes of Thrombosis
    • Bick RL Kaplan H. Syndromes of Thrombosis and Hypercoagulability: Congenital and Acquired Causes of Thrombosis. Med Clin North Am 1998; 82: 409-458.
    • (1998) Med Clin North Am , vol.82 , pp. 409-458
    • Bick, R.L.1    Kaplan, H.2
  • 6
    • 0023634855 scopus 로고
    • Deficient t-PA release and elevated PA inhibitor levels in patients with spontaneous or recurrent deep venous thrombosis
    • Juhan-Vague I Valadier J Alessi M. Deficient t-PA release and elevated PA inhibitor levels in patients with spontaneous or recurrent deep venous thrombosis. Thromb Haemost 1987; 57: 67-72.
    • (1987) Thromb Haemost , vol.57 , pp. 67-72
    • Juhan-Vague, I.1    Valadier, J.2    Alessi, M.3
  • 7
    • 0028920904 scopus 로고
    • Plasminogen deficiency causes severe thrombosis but is compatible with development and reproduction
    • Bugge T Flick M Daugherty C Degen J. Plasminogen deficiency causes severe thrombosis but is compatible with development and reproduction. Genes Dev 1995; 9: 794-807.
    • (1995) Genes Dev , vol.9 , pp. 794-807
    • Bugge, T.1    Flick, M.2    Daugherty, C.3    Degen, J.4
  • 8
    • 33746741718 scopus 로고    scopus 로고
    • Antiphospholipid antibodies and the antiphospholipid syndrome: An update on treatment and pathogenic mechanisms
    • Pierangeli SS Chen PP Gonzalez EB. Antiphospholipid antibodies and the antiphospholipid syndrome: An update on treatment and pathogenic mechanisms. Curr Opin Hematol 2006; 13: 366-375.
    • (2006) Curr Opin Hematol , vol.13 , pp. 366-375
    • Pierangeli, S.S.1    Chen, P.P.2    Gonzalez, E.B.3
  • 9
    • 0023772539 scopus 로고
    • Anti-prothrombin antibodies and the lupus anticoagulant
    • Fleck RA Rapaport SI Rao LV. Anti-prothrombin antibodies and the lupus anticoagulant. Blood 1988; 72: 512-519.
    • (1988) Blood , vol.72 , pp. 512-519
    • Fleck, R.A.1    Rapaport, S.I.2    Rao, L.V.3
  • 10
    • 0025332717 scopus 로고
    • Anti-phospholipid antibodies are directed against a complex antigen that includes a lipid binding inhibitor of coagulation: Beta 2-glycoprotein I (apolipoprotein H)
    • McNeil HP Simpson RJ Chesterman CN Krilis SA. Anti-phospholipid antibodies are directed against a complex antigen that includes a lipid binding inhibitor of coagulation: Beta 2-glycoprotein I (apolipoprotein H). Proc Natl Acad Sci U S A 1990; 87: 4120-4124.
    • (1990) Proc Natl Acad Sci U S A , vol.87 , pp. 4120-4124
    • McNeil, H.P.1    Simpson, R.J.2    Chesterman, C.N.3    Krilis, S.A.4
  • 11
    • 0027253088 scopus 로고
    • Antiphospholipid antibodies directed against a combination of phospholipids with prothrombin, protein C, or protein S: An explanation for their pathogenic mechanism
    • Oosting JD Derksen RHWM Bobbink IWG Hackeng TM Bouma BN de Groot PG. Antiphospholipid antibodies directed against a combination of phospholipids with prothrombin, protein C, or protein S: An explanation for their pathogenic mechanism. Blood 1993; 81: 2618-2625.
    • (1993) Blood , vol.81 , pp. 2618-2625
    • Oosting, J.D.1    Derksen, R.H.W.M.2    Bobbink, I.W.G.3    Hackeng, T.M.4    Bouma, B.N.5    de Groot, P.G.6
  • 12
    • 0025102933 scopus 로고
    • Immunoglobulin G fractions from patients with antiphospholipid antibodies caused fetal death in Balb/c mice: A model for autoimmune fetal loss
    • Branch DW Dudley DJ Mitchell MD. Immunoglobulin G fractions from patients with antiphospholipid antibodies caused fetal death in Balb/c mice: A model for autoimmune fetal loss. Am J Obstet Gynecol 1990; 163: 210-216.
    • (1990) Am J Obstet Gynecol , vol.163 , pp. 210-216
    • Branch, D.W.1    Dudley, D.J.2    Mitchell, M.D.3
  • 13
    • 0033586656 scopus 로고    scopus 로고
    • Antiphospholipid antibodies from antiphospholipid syndrome patients activate endothelial cells in vitro and in vivo
    • Pierangeli SS Colden-Stanfield M Liu XW Barker JH Anderson GL Harris EN. Antiphospholipid antibodies from antiphospholipid syndrome patients activate endothelial cells in vitro and in vivo. Circulation 1999; 99: 1997-2002.
    • (1999) Circulation , vol.99 , pp. 1997-2002
    • Pierangeli, S.S.1    Colden-Stanfield, M.2    Liu, X.W.3    Barker, J.H.4    Anderson, G.L.5    Harris, E.N.6
  • 14
    • 3042797102 scopus 로고    scopus 로고
    • Endothelial cell activation by antiphospholipid antibodies
    • Meroni PL Raschi E Testoni C Borghi MO. Endothelial cell activation by antiphospholipid antibodies. Clin Immunol 2004; 112: 169-174.
    • (2004) Clin Immunol , vol.112 , pp. 169-174
    • Meroni, P.L.1    Raschi, E.2    Testoni, C.3    Borghi, M.O.4
  • 15
    • 33646562520 scopus 로고    scopus 로고
    • Antiphospholipid syndrome: An evolving story
    • Robertson B Greaves M. Antiphospholipid syndrome: An evolving story. Blood Rev 2006; 20: 201-212.
    • (2006) Blood Rev , vol.20 , pp. 201-212
    • Robertson, B.1    Greaves, M.2
  • 16
    • 0023766962 scopus 로고
    • Effect of lupus anticoagulant on antithrombogenic properties of endothelial cells-inhibition of thrombomodulin-dependent protein C activation
    • Cariou R Tobelem G Bellucci S. Effect of lupus anticoagulant on antithrombogenic properties of endothelial cells-inhibition of thrombomodulin-dependent protein C activation. Thromb Haemost 1988; 60: 54-58.
    • (1988) Thromb Haemost , vol.60 , pp. 54-58
    • Cariou, R.1    Tobelem, G.2    Bellucci, S.3
  • 17
    • 0024433923 scopus 로고
    • Impaired catalytic function of activated protein C: A new in vitro manifestation of lupus anticoagulant
    • Marciniak E Romond EH. Impaired catalytic function of activated protein C: A new in vitro manifestation of lupus anticoagulant. Blood 1989; 74: 2426-2432.
    • (1989) Blood , vol.74 , pp. 2426-2432
    • Marciniak, E.1    Romond, E.H.2
  • 18
    • 0025001363 scopus 로고
    • Inhibition of activated protein C and its cofactor protein S by antiphospholipid antibodies
    • Malia RG Kitchen S Greaves M Preston FE. Inhibition of activated protein C and its cofactor protein S by antiphospholipid antibodies. Br J Haematol 1990; 76: 101-107.
    • (1990) Br J Haematol , vol.76 , pp. 101-107
    • Malia, R.G.1    Kitchen, S.2    Greaves, M.3    Preston, F.E.4
  • 19
    • 0026786517 scopus 로고
    • Immunoglobulin fractions isolated from patients with antiphospholipid antibodies prevent the inactivation of factor Va by activated protein C on human endothelial cells
    • Borrell M Sala N de Castellanau C Lopez S Gari M Foncuberta J. Immunoglobulin fractions isolated from patients with antiphospholipid antibodies prevent the inactivation of factor Va by activated protein C on human endothelial cells. Thromb Haemost 1992; 68: 268-272.
    • (1992) Thromb Haemost , vol.68 , pp. 268-272
    • Borrell, M.1    Sala, N.2    de Castellanau, C.3    Lopez, S.4    Gari, M.5    Foncuberta, J.6
  • 20
    • 0032590070 scopus 로고    scopus 로고
    • 2-glycoprotein I is necessary to inhibit protein C activity by monoclonal anticardiolipin antibodies
    • 2-glycoprotein I is necessary to inhibit protein C activity by monoclonal anticardiolipin antibodies. Arthritis Rheum 1999; 42: 167-174.
    • (1999) Arthritis Rheum , vol.42 , pp. 167-174
    • Ieko, M.1    Ichikawa, K.2    Triplett, D.A.3
  • 21
    • 0026582938 scopus 로고
    • Plasma from systemic lupus erythematosus patients with antiphospholipid antibodies promotes platelet aggregation
    • Escolar G Font J Reverter JC. Plasma from systemic lupus erythematosus patients with antiphospholipid antibodies promotes platelet aggregation. Arterioscler Thromb 1992; 12: 196-200.
    • (1992) Arterioscler Thromb , vol.12 , pp. 196-200
    • Escolar, G.1    Font, J.2    Reverter, J.C.3
  • 22
    • 0028959014 scopus 로고
    • Comparison of the effects of anticardiolipin antibodies from patients with the antiphospholipid syndrome and with syphilis on platelet activation and aggregation
    • Campbell AL Pierangeli SS Wellhausen S Harris EN. Comparison of the effects of anticardiolipin antibodies from patients with the antiphospholipid syndrome and with syphilis on platelet activation and aggregation. Thromb Haemost 1995; 73: 529-534.
    • (1995) Thromb Haemost , vol.73 , pp. 529-534
    • Campbell, A.L.1    Pierangeli, S.S.2    Wellhausen, S.3    Harris, E.N.4
  • 23
    • 4444273214 scopus 로고    scopus 로고
    • Intracellular events in platelet activation induced by antiphospholipid antibodies in the presence of low doses of thrombin
    • Vega-Ostertag M Harris EN Pierangeli SS. Intracellular events in platelet activation induced by antiphospholipid antibodies in the presence of low doses of thrombin. Arthritis Rheum 2004; 50: 2911-2919.
    • (2004) Arthritis Rheum , vol.50 , pp. 2911-2919
    • Vega-Ostertag, M.1    Harris, E.N.2    Pierangeli, S.S.3
  • 24
    • 0028365677 scopus 로고
    • Induction of tissue factor-like activity in monocytes by anti-cardiolipin antibodies
    • Kornberg A Blank M Kaufman S Shoenfeld Y. Induction of tissue factor-like activity in monocytes by anti-cardiolipin antibodies. J Immunol 1994; 153: 1328-1332.
    • (1994) J Immunol , vol.153 , pp. 1328-1332
    • Kornberg, A.1    Blank, M.2    Kaufman, S.3    Shoenfeld, Y.4
  • 25
    • 0028883356 scopus 로고
    • Activation of cultured vascular endothelial cells by antiphospholipid antibodies
    • Simantov R LaSala JM Lo SK. Activation of cultured vascular endothelial cells by antiphospholipid antibodies. J Clin Invest 1995; 96: 2211-2219.
    • (1995) J Clin Invest , vol.96 , pp. 2211-2219
    • Simantov, R.1    LaSala, J.M.2    Lo, S.K.3
  • 27
    • 1842413134 scopus 로고    scopus 로고
    • Thrombosis in primary antiphospholipid syndrome - A pivotal role for monocyte tissue factor expression
    • Cuadrado MJ López-Pedrera C Khamashta MA. Thrombosis in primary antiphospholipid syndrome - A pivotal role for monocyte tissue factor expression. Arthritis Rheum 1997; 40: 834-841.
    • (1997) Arthritis Rheum , vol.40 , pp. 834-841
    • Cuadrado, M.J.1    López-Pedrera, C.2    Khamashta, M.A.3
  • 28
    • 0031886679 scopus 로고    scopus 로고
    • The role of the tissue factor pathway in the hypercoagulable state in patients with the antiphospholipid syndrome
    • Amengual O Atsumi T Khamashta MA Hughes GRV. The role of the tissue factor pathway in the hypercoagulable state in patients with the antiphospholipid syndrome. Thromb Haemost 1998; 79: 276-281.
    • (1998) Thromb Haemost , vol.79 , pp. 276-281
    • Amengual, O.1    Atsumi, T.2    Khamashta, M.A.3    Hughes, G.R.V.4
  • 29
    • 18644361988 scopus 로고    scopus 로고
    • Involvement of p38 MAPK in the up-regulation of tissue factor on endothelial cells by antiphospholipid antibodies
    • Vega-Ostertag M Casper K Swerlick R Ferrara D Harris EN Pierangeli SS. Involvement of p38 MAPK in the up-regulation of tissue factor on endothelial cells by antiphospholipid antibodies. Arthritis Rheum 2005; 52: 1545-1554.
    • (2005) Arthritis Rheum , vol.52 , pp. 1545-1554
    • Vega-Ostertag, M.1    Casper, K.2    Swerlick, R.3    Ferrara, D.4    Harris, E.N.5    Pierangeli, S.S.6
  • 30
    • 0027256798 scopus 로고
    • Inhibition of heparin/antithrombin III cofactor activity by anticardiolipin antibodies: A mechanism for thrombosis
    • Chamley LW McKay EJ Pattison NS. Inhibition of heparin/antithrombin III cofactor activity by anticardiolipin antibodies: A mechanism for thrombosis. Thromb Res 1993; 71: 103-111.
    • (1993) Thromb Res , vol.71 , pp. 103-111
    • Chamley, L.W.1    McKay, E.J.2    Pattison, N.S.3
  • 31
    • 0035893021 scopus 로고    scopus 로고
    • Identification of anti-thrombin antibodies in the antiphospholipid syndrome that interfere with the inactivation of thrombin by antithrombin
    • Hwang K Grossman J Visvanathan S. et al. Identification of anti-thrombin antibodies in the antiphospholipid syndrome that interfere with the inactivation of thrombin by antithrombin. J Immunol 2001; 167: 7192-7198.
    • (2001) J Immunol , vol.167 , pp. 7192-7198
    • Hwang, K.1    Grossman, J.2    Visvanathan, S.3
  • 32
    • 0037148520 scopus 로고    scopus 로고
    • Complement c3 activation is required for antiphospholipid antibody-induced fetal loss
    • Holers V Girardi G Mo L. et al. Complement c3 activation is required for antiphospholipid antibody-induced fetal loss. J Exp Med 2002; 195: 211-220.
    • (2002) J Exp Med , vol.195 , pp. 211-220
    • Holers, V.1    Girardi, G.2    Mo, L.3
  • 33
    • 22244485396 scopus 로고    scopus 로고
    • Requirement of activation of complement C3 and C5 for antiphospholipid antibody-mediated thrombophilia
    • Pierangeli SS Girardi G Vega-Ostertag M Liu X Espinola RG Salmon J. Requirement of activation of complement C3 and C5 for antiphospholipid antibody-mediated thrombophilia. Arthritis Rheum 2005; 52: 2120-2124.
    • (2005) Arthritis Rheum , vol.52 , pp. 2120-2124
    • Pierangeli, S.S.1    Girardi, G.2    Vega-Ostertag, M.3    Liu, X.4    Espinola, R.G.5    Salmon, J.6
  • 34
    • 33744481250 scopus 로고    scopus 로고
    • Autoantibodies against the fibrinolytic receptor, annexin 2, in antiphospholipid syndrome
    • Cesarman-Maus G Rios-Luna NP Deora AB. et al. Autoantibodies against the fibrinolytic receptor, annexin 2, in antiphospholipid syndrome. Blood 2006; 107: 4375-4382.
    • (2006) Blood , vol.107 , pp. 4375-4382
    • Cesarman-Maus, G.1    Rios-Luna, N.P.2    Deora, A.B.3
  • 35
    • 9444270934 scopus 로고    scopus 로고
    • A monoclonal IgG anticardiolipin antibody from a patient with the antiphospholipid syndrome is thrombogenic in mice
    • Olee TW Pierangeli SS Handley HH. et al. A monoclonal IgG anticardiolipin antibody from a patient with the antiphospholipid syndrome is thrombogenic in mice. Proc Natl Acad Sci U S A 1996; 93: 8606-8611.
    • (1996) Proc Natl Acad Sci U SA , vol.93 , pp. 8606-8611
    • Olee, T.W.1    Pierangeli, S.S.2    Handley, H.H.3
  • 36
    • 0032892020 scopus 로고    scopus 로고
    • Characterization of IgG monoclonal anti-cardiolipin/antib2GP1 antibodies from two patients with the anti-phospholipid syndrome reveals three species of antibodies
    • Zhu M Olee T Le DT. et al. Characterization of IgG monoclonal anti-cardiolipin/antib2GP1 antibodies from two patients with the anti-phospholipid syndrome reveals three species of antibodies. Br J Haematol 1999; 105: 102-109.
    • (1999) Br J Haematol , vol.105 , pp. 102-109
    • Zhu, M.1    Olee, T.2    Le, D.T.3
  • 37
    • 0033832202 scopus 로고    scopus 로고
    • Functional analyses of patient-derived IgG monoclonal anticardiolipin antibodies using in vivo thrombosis and in vivo microcirculation models
    • Pierangeli SS Liu XW Espinola R. et al. Functional analyses of patient-derived IgG monoclonal anticardiolipin antibodies using in vivo thrombosis and in vivo microcirculation models. Thromb Haemost 2000; 84: 388-395.
    • (2000) Thromb Haemost , vol.84 , pp. 388-395
    • Pierangeli, S.S.1    Liu, X.W.2    Espinola, R.3
  • 38
    • 0033495741 scopus 로고    scopus 로고
    • An IgG anti-prothrombin antibody enhances prothrombin binding to damaged endothelial cells and shortens plasma coagulation times
    • Zhao Y Rumold R Ahmed AE. et al. An IgG anti-prothrombin antibody enhances prothrombin binding to damaged endothelial cells and shortens plasma coagulation times. Arthritis Rheum 1999; 42: 2132-2138.
    • (1999) Arthritis Rheum , vol.42 , pp. 2132-2138
    • Zhao, Y.1    Rumold, R.2    Ahmed, A.E.3
  • 39
    • 33751578678 scopus 로고    scopus 로고
    • Antibodies against the activated coagulation factor X (FXa) in the antiphospholipid syndrome that interfere with the FXa inactivation by antithrombin
    • Yang YH Hwang KK FitzGerald J. et al. Antibodies against the activated coagulation factor X (FXa) in the antiphospholipid syndrome that interfere with the FXa inactivation by antithrombin. J Immunol 2006; 177: 8219-8225.
    • (2006) J Immunol , vol.177 , pp. 8219-8225
    • Yang, Y.H.1    Hwang, K.K.2    FitzGerald, J.3
  • 40
    • 0037975660 scopus 로고    scopus 로고
    • A thrombin-cross-reactive anticardiolipin antibody binds to and inhibits the anticoagulant function of activated protein C
    • Hwang KK Yang CD Yan W Grossman JM Hahn BH Chen PP. A thrombin-cross-reactive anticardiolipin antibody binds to and inhibits the anticoagulant function of activated protein C. Arthritis Rheum 2003; 48: 1622-1630.
    • (2003) Arthritis Rheum , vol.48 , pp. 1622-1630
    • Hwang, K.K.1    Yang, C.D.2    Yan, W.3    Grossman, J.M.4    Hahn, B.H.5    Chen, P.P.6
  • 41
    • 2142704424 scopus 로고    scopus 로고
    • Identification of anti-plasmin antibodies in the antiphospholipid syndrome that inhibit degradation of fibrin
    • Yang CD Hwang KK Yan W. et al. Identification of anti-plasmin antibodies in the antiphospholipid syndrome that inhibit degradation of fibrin. J Immunol 2004; 172: 5765-5773.
    • (2004) J Immunol , vol.172 , pp. 5765-5773
    • Yang, C.D.1    Hwang, K.K.2    Yan, W.3
  • 42
    • 33748748970 scopus 로고    scopus 로고
    • A human monoclonal antiprothrombin antibody is thrombogenic in vivo and upregulates expression of tissue factor and E-selectin on endothelial cells
    • Vega-Ostertag M Liu X Kwan-Ki H Chen P Pierangeli S. A human monoclonal antiprothrombin antibody is thrombogenic in vivo and upregulates expression of tissue factor and E-selectin on endothelial cells. Br J Haematol 2006; 135: 214-219.
    • (2006) Br J Haematol , vol.135 , pp. 214-219
    • Vega-Ostertag, M.1    Liu, X.2    Kwan-Ki, H.3    Chen, P.4    Pierangeli, S.5
  • 43
    • 0036125784 scopus 로고    scopus 로고
    • Immunoglobulin g from patients with antiphospholipid syndrome impairs the fibrin dissolution with plasmin
    • Kolev K Gombas J Varadi B. et al. Immunoglobulin g from patients with antiphospholipid syndrome impairs the fibrin dissolution with plasmin. Thromb Haemost 2002; 87: 502-508.
    • (2002) Thromb Haemost , vol.87 , pp. 502-508
    • Kolev, K.1    Gombas, J.2    Varadi, B.3
  • 44
    • 0030589375 scopus 로고    scopus 로고
    • The anti-b2-glycoprotein I activity in human anti-phospholipid syndrome sera is due to monoreactive low-affinity autoantibodies directed to epitopes located on native b2-glycoprotein I and preserved during species' evolution
    • Tincani A Spatola L Prati E. et al. The anti-b2-glycoprotein I activity in human anti-phospholipid syndrome sera is due to monoreactive low-affinity autoantibodies directed to epitopes located on native b2-glycoprotein I and preserved during species' evolution. J Immunol 1996; 157: 5732-5738.
    • (1996) J Immunol , vol.157 , pp. 5732-5738
    • Tincani, A.1    Spatola, L.2    Prati, E.3
  • 45
    • 34247153549 scopus 로고    scopus 로고
    • Some plasmin-induced antibodies bind to cardiolipin, display lupus anticoagulant activity and induce fetal loss in mice
    • Chen XX Gu YY Li SJ. et al. Some plasmin-induced antibodies bind to cardiolipin, display lupus anticoagulant activity and induce fetal loss in mice. J Immunol 2007; 178: 5351-5356.
    • (2007) J Immunol , vol.178 , pp. 5351-5356
    • Chen, X.X.1    Gu, Y.Y.2    Li, S.J.3
  • 46
    • 0018135382 scopus 로고
    • A sensitive test demonstrating lupus anticoagulant and its behavioural patterns
    • Exner T Rickard KA Kronenberg H. A sensitive test demonstrating lupus anticoagulant and its behavioural patterns. Br J Haematol 1978; 40: 143-151.
    • (1978) Br J Haematol , vol.40 , pp. 143-151
    • Exner, T.1    Rickard, K.A.2    Kronenberg, H.3
  • 47
    • 29144503118 scopus 로고    scopus 로고
    • Identification of polyclonal and monoclonal antibodies against tissue plasminogen activator in the antiphospholipid syndrome
    • Lu CS Horizon AA Hwang KK. et al. Identification of polyclonal and monoclonal antibodies against tissue plasminogen activator in the antiphospholipid syndrome. Arthritis Rheum 2005; 52: 4018-4027.
    • (2005) Arthritis Rheum , vol.52 , pp. 4018-4027
    • Lu, C.S.1    Horizon, A.A.2    Hwang, K.K.3
  • 48
    • 1542373659 scopus 로고    scopus 로고
    • Antibodies to tissue-type plasminogen activator (tPA) in patients with antiphospholipid syndrome: Evidence of interaction between the antibodies and the catalytic domain of tPA in 2 patients
    • Cugno M Cabibbe M Galli M. et al. Antibodies to tissue-type plasminogen activator (tPA) in patients with antiphospholipid syndrome: Evidence of interaction between the antibodies and the catalytic domain of tPA in 2 patients. Blood 2004; 103: 2121-2126
    • (2004) Blood , vol.103 , pp. 2121-2126
    • Cugno, M.1    Cabibbe, M.2    Galli, M.3
  • 49
    • 34248523994 scopus 로고    scopus 로고
    • Some antiphospholipid antibodies recognize conformational epitopes shared by beta(2)-glycoprotein I and the homologous catalytic domains of several serine proteases
    • Lin WS Chen PC Yang CD. et al. Some antiphospholipid antibodies recognize conformational epitopes shared by beta(2)-glycoprotein I and the homologous catalytic domains of several serine proteases. Arthritis Rheum 2007; 56: 1638-1647.
    • (2007) Arthritis Rheum , vol.56 , pp. 1638-1647
    • Lin, W.S.1    Chen, P.C.2    Yang, C.D.3


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