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Volumn 6, Issue 2, 2009, Pages 64-65

Which questions remain unanswered following the successful development of sorafenib in hepatocellular carcinoma?

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOGENESIS INHIBITOR; BEVACIZUMAB; DOXORUBICIN; MITOGEN ACTIVATED PROTEIN KINASE; PLACEBO; SORAFENIB; VASCULOTROPIN;

EID: 59549085596     PISSN: 17434254     EISSN: 17434262     Source Type: Journal    
DOI: 10.1038/ncponc1299     Document Type: Note
Times cited : (4)

References (8)
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    • Sorafenib blocks the RAF/MEK/ERK pathway, inhibits tumor angiogenesis, and induces tumor cell apoptosis in hepatocellular carcinoma model PLC/PRF/5
    • Liu L et al. (2006) Sorafenib blocks the RAF/MEK/ERK pathway, inhibits tumor angiogenesis, and induces tumor cell apoptosis in hepatocellular carcinoma model PLC/PRF/5. Cancer Res 66: 11851-11858
    • (2006) Cancer Res , vol.66 , pp. 11851-11858
    • Liu, L.1
  • 2
    • 33750917456 scopus 로고    scopus 로고
    • Bevacizumab in unresectable hepatocellular carcinoma (HCC) for patients without metastasis and without invasion of the portal vein [abstract]
    • Schwartz JD et al. (2006) Bevacizumab in unresectable hepatocellular carcinoma (HCC) for patients without metastasis and without invasion of the portal vein [abstract]. J Clin Oncol 24 (suppl): S213
    • (2006) J Clin Oncol , vol.24 , Issue.SUPPL.
    • Schwartz, J.D.1
  • 3
    • 33646351795 scopus 로고    scopus 로고
    • Phase II study of gemcitabine and oxaliplatin in combination with bevacizumab in patients with advanced hepatocellular carcinoma
    • Zhu AX et al. (2006) Phase II study of gemcitabine and oxaliplatin in combination with bevacizumab in patients with advanced hepatocellular carcinoma. J Clin Oncol 24: 1898-1903
    • (2006) J Clin Oncol , vol.24 , pp. 1898-1903
    • Zhu, A.X.1
  • 4
    • 36549089272 scopus 로고    scopus 로고
    • Combination of capecitabine, oxaliplatin and bevacizumab in treatment of advanced hepatoce llular carcinoma: A phase II study [abstract]
    • Sun W et al. (2007) Combination of capecitabine, oxaliplatin and bevacizumab in treatment of advanced hepatoce llular carcinoma: A phase II study [abstract]. J Clin Oncol 25: (suppl): S240
    • (2007) J Clin Oncol , vol.25 , Issue.SUPPL.
    • Sun, W.1
  • 5
    • 33749017926 scopus 로고    scopus 로고
    • Phase II study of sorafenib in patients with advanced hepatocellular carcinoma
    • Abou-Alfa GK et al. (2006) Phase II study of sorafenib in patients with advanced hepatocellular carcinoma. J Clin Oncol 24: 4293-4300
    • (2006) J Clin Oncol , vol.24 , pp. 4293-4300
    • Abou-Alfa, G.K.1
  • 6
    • 47949116252 scopus 로고    scopus 로고
    • Sorafenib in advanced hepatocelluar carcinoma
    • Llovet JM et al. (2008) Sorafenib in advanced hepatocelluar carcinoma. N Engl J Med 359: 378-390
    • (2008) N Engl J Med , vol.359 , pp. 378-390
    • Llovet, J.M.1
  • 7
    • 58049220774 scopus 로고    scopus 로고
    • Randomized phase III trial of sorafenib versus placebo in Asian patients with advanced hepatocellular carcinoma [abstract]
    • Cheng A et al. (2008) Randomized phase III trial of sorafenib versus placebo in Asian patients with advanced hepatocellular carcinoma [abstract]. J Clin Oncol 26: 4509
    • (2008) J Clin Oncol , vol.26 , pp. 4509
    • Cheng, A.1
  • 8
    • 48249092297 scopus 로고    scopus 로고
    • Final results from a phase II, randomized, double-blind study of sorafenib plus doxorubicin versus placebo plus doxorubicin in patients with advanced hepatocellular carcinoma
    • abstract #128, FL
    • Abou-Alfa GK et al. (2008) Final results from a phase II, randomized, double-blind study of sorafenib plus doxorubicin versus placebo plus doxorubicin in patients with advanced hepatocellular carcinoma [abstract #128]. 2008 Gastrointestinal Cancers Symposium: 2008 January 24-27; Orlando, FL.
    • (2008) 2008 Gastrointestinal Cancers Symposium: 2008 January 24-27; Orlando
    • Abou-Alfa, G.K.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.