메뉴 건너뛰기




Volumn 8, Issue 6, 2008, Pages 419-427

Cost effectiveness of ezetimibe in patients with cardiovascular disease and statin intolerance or contraindications: A Markov model

Author keywords

Cardiovascular disorders, treatment; Cholesterol absorption inhibitors, therapeutic use; Cost analysis; Drug tolerance; Ezetimibe, therapeutic use

Indexed keywords

EZETIMIBE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; LOW DENSITY LIPOPROTEIN CHOLESTEROL;

EID: 59449103939     PISSN: 11753277     EISSN: None     Source Type: Journal    
DOI: 10.2165/0129784-200808060-00005     Document Type: Article
Times cited : (20)

References (49)
  • 1
    • 33845443582 scopus 로고    scopus 로고
    • 2006 edition. Oxford: British Heart Foundation Health Promotion Research Group, Department of Public Health, University of Oxford
    • Allender S, Peto V, Scarborough P, et al. Coronary heart disease statistics 2006 edition. Oxford: British Heart Foundation Health Promotion Research Group, Department of Public Health, University of Oxford, 2006
    • (2006) Coronary heart disease statistics
    • Allender, S.1    Peto, V.2    Scarborough, P.3
  • 3
    • 33644810298 scopus 로고    scopus 로고
    • British Cardiac Society, British Hypertension Society, Diabetes UK, et al. JBS 2: Joint British Societies' guidelines on prevention of cardiovascular disease in clinical practice. Heart 2005; 91 Suppl. 5: V1-V52
    • British Cardiac Society, British Hypertension Society, Diabetes UK, et al. JBS 2: Joint British Societies' guidelines on prevention of cardiovascular disease in clinical practice. Heart 2005; 91 Suppl. 5: V1-V52
  • 4
    • 33644932647 scopus 로고    scopus 로고
    • Levels of dyslipidaemia and improvement in its management in England: Results from the Health Survey for England 2003
    • Primatesta P, Poulter NR. Levels of dyslipidaemia and improvement in its management in England: results from the Health Survey for England 2003. Clin Endocrinol (Oxf) 2006; 64 (3): 292-8
    • (2006) Clin Endocrinol (Oxf) , vol.64 , Issue.3 , pp. 292-298
    • Primatesta, P.1    Poulter, N.R.2
  • 5
    • 26244432388 scopus 로고    scopus 로고
    • Efficacy and safety of cholesterol-lowering treatment: Prospective meta-analysis of data from 90,056 participants in 14 randomised trials of statins
    • Oct 8;
    • Baigent C, Keech A, Kearney PM, et al. Efficacy and safety of cholesterol-lowering treatment: prospective meta-analysis of data from 90,056 participants in 14 randomised trials of statins. Lancet 2005 Oct 8; 366 (9493): 1267-78
    • (2005) Lancet , vol.366 , Issue.9493 , pp. 1267-1278
    • Baigent, C.1    Keech, A.2    Kearney, P.M.3
  • 6
    • 0003173837 scopus 로고    scopus 로고
    • Cholesterol and coronary heart disease: Screening and treatment
    • NHS Centre for Reviews and Dissemination
    • NHS Centre for Reviews and Dissemination. Cholesterol and coronary heart disease: screening and treatment. Effective Health Care Bull 1998; 4 (1): 1-16
    • (1998) Effective Health Care Bull , vol.4 , Issue.1 , pp. 1-16
  • 7
    • 0141906386 scopus 로고    scopus 로고
    • Ezetimibe for lowering blood cholesterol
    • Husereau DR. Ezetimibe for lowering blood cholesterol. Issues Emerg Health Technol 2003; (49): 1-4
    • (2003) Issues Emerg Health Technol , vol.49 , pp. 1-4
    • Husereau, D.R.1
  • 8
    • 34748924577 scopus 로고    scopus 로고
    • European guidelines on cardiovascular disease prevention in clinical practice: Executive summary
    • Sep;
    • Graham I, Atar D, Borch-Johnsen K, et al. European guidelines on cardiovascular disease prevention in clinical practice: executive summary. Atherosclerosis 2007 Sep; 194 (1): 1-45
    • (2007) Atherosclerosis , vol.194 , Issue.1 , pp. 1-45
    • Graham, I.1    Atar, D.2    Borch-Johnsen, K.3
  • 9
    • 8844246477 scopus 로고    scopus 로고
    • Implications of recent clinical trials for the National Cholesterol Education Program Adult Treatment Panel III guidelines
    • Grundy SM, Cleeman JI, Bairey Merz CN, et al. Implications of recent clinical trials for the National Cholesterol Education Program Adult Treatment Panel III guidelines. Arterioscler Thromb Vasc Biol 2004; 24 (8): e149-61
    • (2004) Arterioscler Thromb Vasc Biol , vol.24 , Issue.8
    • Grundy, S.M.1    Cleeman, J.I.2    Bairey Merz, C.N.3
  • 10
    • 51549108029 scopus 로고    scopus 로고
    • Ara R, Tumur I, Pandor A, et al. Ezetimibe for the treatment of hypercholesterolaemia: a systematic review and economic evaluation. Health Technol Assess 2008 May; 12 (21): iii, xi-xiii, 1-212
    • Ara R, Tumur I, Pandor A, et al. Ezetimibe for the treatment of hypercholesterolaemia: a systematic review and economic evaluation. Health Technol Assess 2008 May; 12 (21): iii, xi-xiii, 1-212
  • 11
    • 59449104941 scopus 로고    scopus 로고
    • Health & Social Care Information Centre prescription cost analysis, online, Available from URL:, Accessed 2006 Oct 9
    • Health & Social Care Information Centre prescription cost analysis 2005 [online]. Available from URL: http://www.ic.nhs.uk/pubs/ prescostanalysis2005 [Accessed 2006 Oct 9]
    • (2005)
  • 12
    • 0021350001 scopus 로고
    • The Lipid Research Clinics Coronary Primary Prevention Trial results: I. Reduction in incidence of coronary heart disease
    • Lipid Research Clinics Program
    • Lipid Research Clinics Program. The Lipid Research Clinics Coronary Primary Prevention Trial results: I. Reduction in incidence of coronary heart disease. JAMA 1984; 251: 351-64
    • (1984) JAMA , vol.251 , pp. 351-364
  • 13
    • 11844304073 scopus 로고    scopus 로고
    • Benefits of niacin by glycemic status in patients with healed myocardial infarction (from the Coronary Drug Project)
    • Canner P, Furberg C, Terrin M, et al. Benefits of niacin by glycemic status in patients with healed myocardial infarction (from the Coronary Drug Project). Am J Cardiol 2005; 95: 254-7
    • (2005) Am J Cardiol , vol.95 , pp. 254-257
    • Canner, P.1    Furberg, C.2    Terrin, M.3
  • 14
    • 28044452217 scopus 로고    scopus 로고
    • FIELD study investigators. Effects of long-term fenofibrate therapy on cardiovascular events in 9795 people with type 2 diabetes mellitus (the FIELD study): Randomised controlled trial
    • Keech A, Simes R, Barter P, et al. FIELD study investigators. Effects of long-term fenofibrate therapy on cardiovascular events in 9795 people with type 2 diabetes mellitus (the FIELD study): randomised controlled trial. Lancet 2005; 366: 1849-61
    • (2005) Lancet , vol.366 , pp. 1849-1861
    • Keech, A.1    Simes, R.2    Barter, P.3
  • 16
    • 70449517205 scopus 로고    scopus 로고
    • Statins for the prevention of cardiovascular events: An analysis of the clinical and cost effectiveness of statins in patients with, or at risk from, coronary heart disease (CHD)
    • Ward S, Lloyd-Jones M, Pandor A, et al. Statins for the prevention of cardiovascular events: an analysis of the clinical and cost effectiveness of statins in patients with, or at risk from, coronary heart disease (CHD). Health Technol Assess 2007; 11 (14): 1-340
    • (2007) Health Technol Assess , vol.11 , Issue.14 , pp. 1-340
    • Ward, S.1    Lloyd-Jones, M.2    Pandor, A.3
  • 17
    • 0027772390 scopus 로고
    • Markov models in medical decision making: A practical guide
    • Sonnenberg F, Beck J. Markov models in medical decision making: a practical guide. Med Decision Making 1993; 13: 322-39
    • (1993) Med Decision Making , vol.13 , pp. 322-339
    • Sonnenberg, F.1    Beck, J.2
  • 18
    • 39449138964 scopus 로고    scopus 로고
    • online, Available from URL:, Accessed 2006 Oct
    • British National Formulary [online]. Available from URL: http://www.bnf.org/bnf/ [Accessed 2006 Oct]
    • British National Formulary
  • 19
    • 0027360437 scopus 로고
    • Twenty years' experience of myocardial infarction: The value of a heart attack register. Nottingham Heart Attack Register
    • Gray D, Hampton J. Twenty years' experience of myocardial infarction: the value of a heart attack register. Nottingham Heart Attack Register. Br J Clin Pharmacol 1993; 47: 292-5
    • (1993) Br J Clin Pharmacol , vol.47 , pp. 292-295
    • Gray, D.1    Hampton, J.2
  • 20
    • 0036157987 scopus 로고    scopus 로고
    • Incidence and case fatality rates of stroke subtypes in a multiethnic population: The South London Stroke Register
    • Wolfe CDA, Rudd AG, Howard R, et al. Incidence and case fatality rates of stroke subtypes in a multiethnic population: the South London Stroke Register. J Neurol Neurosurg Psychiatry 2002; 72: 211-6
    • (2002) J Neurol Neurosurg Psychiatry , vol.72 , pp. 211-216
    • Wolfe, C.D.A.1    Rudd, A.G.2    Howard, R.3
  • 21
    • 59449090508 scopus 로고    scopus 로고
    • Palmer S, Sculpher M, Philips Z, et al. A cost-effectiveness model comparing alternative management strategies for the use of glycoprotein IIb/IIIa antagonists in non-ST-elevation acute coronary syndrome. Report to the National Institute for Clinical Excellence. London: NICE, 2002 [online]. Available from URL: http://www.nice.org.uk [Accessed 2006 Sep]
    • Palmer S, Sculpher M, Philips Z, et al. A cost-effectiveness model comparing alternative management strategies for the use of glycoprotein IIb/IIIa antagonists in non-ST-elevation acute coronary syndrome. Report to the National Institute for Clinical Excellence. London: NICE, 2002 [online]. Available from URL: http://www.nice.org.uk [Accessed 2006 Sep]
  • 22
    • 0037225456 scopus 로고    scopus 로고
    • The economic burden of stroke in the United Kingdom
    • Youman P, Wilson K, Harraf F, et al. The economic burden of stroke in the United Kingdom. Pharmacoeconomics 2003; Suppl. 1: 43-50
    • (2003) Pharmacoeconomics , vol.1 , Issue.SUPPL. , pp. 43-50
    • Youman, P.1    Wilson, K.2    Harraf, F.3
  • 23
    • 0037783946 scopus 로고    scopus 로고
    • The impact of diabetes-related complications on healthcare costs: Results from the United Kingdom Prospective Diabetes Study (UKPDS Study No. 65)
    • Clarke P, Gray A, Legood R, et al. The impact of diabetes-related complications on healthcare costs: results from the United Kingdom Prospective Diabetes Study (UKPDS Study No. 65). Diabet Med 2003; 20 (6): 442-50
    • (2003) Diabet Med , vol.20 , Issue.6 , pp. 442-450
    • Clarke, P.1    Gray, A.2    Legood, R.3
  • 24
    • 33745894961 scopus 로고    scopus 로고
    • Pharmacological treatment and perceived health status during 1-year follow up in patients diagnosed with coronary artery disease, but ineligible for revascularization. Results from the Euro Heart Survey on Coronary Revascularization
    • Lenzen M, Scholte op Reimer W, Norekval T, et al. Pharmacological treatment and perceived health status during 1-year follow up in patients diagnosed with coronary artery disease, but ineligible for revascularization. Results from the Euro Heart Survey on Coronary Revascularization. Eur J Cardiovasc Nurs 2006; 5: 115-21
    • (2006) Eur J Cardiovasc Nurs , vol.5 , pp. 115-121
    • Lenzen, M.1    Scholte op Reimer, W.2    Norekval, T.3
  • 25
    • 0003193846 scopus 로고
    • Protocol for the Bypass Angioplasty Revascularization Investigation
    • BARI Investigators
    • BARI Investigators. Protocol for the Bypass Angioplasty Revascularization Investigation. Circulation 1991; 84 Suppl. 6: 1-27
    • (1991) Circulation , vol.84 , Issue.SUPPL. 6 , pp. 1-27
  • 26
    • 11844296117 scopus 로고    scopus 로고
    • Health-related quality of life after interventional or conservative strategy in patients with unstable angina or non-ST-segment elevation myocardial infarction: One year results of the third randomized intervention trial of unstable angina (RITA-3)
    • Kim J, Henderson R, Pocock SJ, et al. Health-related quality of life after interventional or conservative strategy in patients with unstable angina or non-ST-segment elevation myocardial infarction: one year results of the third randomized intervention trial of unstable angina (RITA-3). J Am Coll Cardiol 2007; 45: 221-8
    • (2007) J Am Coll Cardiol , vol.45 , pp. 221-228
    • Kim, J.1    Henderson, R.2    Pocock, S.J.3
  • 27
    • 10744232654 scopus 로고    scopus 로고
    • Randomised controlled trial and economic evaluation of a chest pain observation unit compared with routine care
    • Goodacre S, Nicholl J, Dixon S, et al. Randomised controlled trial and economic evaluation of a chest pain observation unit compared with routine care. BMJ 2004; 328: 254-7
    • (2004) BMJ , vol.328 , pp. 254-257
    • Goodacre, S.1    Nicholl, J.2    Dixon, S.3
  • 28
    • 0041766811 scopus 로고    scopus 로고
    • Continuing inequality: Gender and social class influences on self perceived health after a heart attack
    • Lacey EA, Walters SJ. Continuing inequality: gender and social class influences on self perceived health after a heart attack. J Epidemiol Commun Health 2003; 57: 622-7
    • (2003) J Epidemiol Commun Health , vol.57 , pp. 622-627
    • Lacey, E.A.1    Walters, S.J.2
  • 29
    • 1642314085 scopus 로고    scopus 로고
    • Assessment of post-stroke quality of life in cost-effectiveness studies: The usefulness of the Barthel Index and the EuroQol-5D
    • Van Exel N, Scholte op Reimer W, Koopmanschap MA. Assessment of post-stroke quality of life in cost-effectiveness studies: the usefulness of the Barthel Index and the EuroQol-5D. Qual Life Res 2004; 13: 427-33
    • (2004) Qual Life Res , vol.13 , pp. 427-433
    • Van Exel, N.1    Scholte op Reimer, W.2    Koopmanschap, M.A.3
  • 30
    • 10444261218 scopus 로고    scopus 로고
    • The impact of discharge to a care home on longer term stroke outcomes
    • Leeds L, Meara J, Hobson P. The impact of discharge to a care home on longer term stroke outcomes. Clin Rehabil 2004; 18: 924-8
    • (2004) Clin Rehabil , vol.18 , pp. 924-928
    • Leeds, L.1    Meara, J.2    Hobson, P.3
  • 31
    • 13844255112 scopus 로고    scopus 로고
    • Responsiveness of generic health-related quality of life measures in stroke
    • Pickard AS, Johnson JA, Feeny DH. Responsiveness of generic health-related quality of life measures in stroke. Qual Life Res 2005; 14: 207-19
    • (2005) Qual Life Res , vol.14 , pp. 207-219
    • Pickard, A.S.1    Johnson, J.A.2    Feeny, D.H.3
  • 32
    • 0032492429 scopus 로고    scopus 로고
    • Variations in population health status: Results from a United Kingdom national questionnaire survey
    • Kind P, Dolan P, Gudex C, et al. Variations in population health status: results from a United Kingdom national questionnaire survey. BMJ 1998; 316: 736-41
    • (1998) BMJ , vol.316 , pp. 736-741
    • Kind, P.1    Dolan, P.2    Gudex, C.3
  • 33
    • 59449091958 scopus 로고    scopus 로고
    • National Institute for Clinical Excellence (NICE). Guide to the methods of technology appraisal [reference NO515; online]. Available from URL: http://www.nice.org.uk [Accessed 2006 Sep]
    • National Institute for Clinical Excellence (NICE). Guide to the methods of technology appraisal [reference NO515; online]. Available from URL: http://www.nice.org.uk [Accessed 2006 Sep]
  • 34
    • 0032492429 scopus 로고    scopus 로고
    • Variations in population health status: Results from a United Kingdom national questionnaire survey
    • Kind. P, Dolan P, Gudex C, Williams A. Variations in population health status: results from a United Kingdom national questionnaire survey. BMJ 1998; 316 (7133): 736-41
    • (1998) BMJ , vol.316 , Issue.7133 , pp. 736-741
    • Kind, P.1    Dolan, P.2    Gudex, C.3    Williams, A.4
  • 35
    • 0037111924 scopus 로고    scopus 로고
    • Efficacy and safety of a potent new selective cholesterol absorption inhibitor, ezetimibe, in patients with primary hypercholesterolemia
    • Nov 15;
    • Dujovne CA, Ettinger MP, McNeer JF, et al. Efficacy and safety of a potent new selective cholesterol absorption inhibitor, ezetimibe, in patients with primary hypercholesterolemia. Am J Cardiol 2002 Nov 15; 90 (10): 1092-7
    • (2002) Am J Cardiol , vol.90 , Issue.10 , pp. 1092-1097
    • Dujovne, C.A.1    Ettinger, M.P.2    McNeer, J.F.3
  • 36
    • 0037504445 scopus 로고    scopus 로고
    • Effect of ezetimibe coadministered with atorvastatin in 628 patients with primary hypercholesterolemia: A prospective, randomized, double-blind trial
    • Ballantyne CM, Houri J, Notarbartolo A, et al. Effect of ezetimibe coadministered with atorvastatin in 628 patients with primary hypercholesterolemia: a prospective, randomized, double-blind trial. Circulation 2003; 107 (19): 2409-15
    • (2003) Circulation , vol.107 , Issue.19 , pp. 2409-2415
    • Ballantyne, C.M.1    Houri, J.2    Notarbartolo, A.3
  • 37
    • 0037395141 scopus 로고    scopus 로고
    • Effects of ezetimibe, a new cholesterol absorption inhibitor, on plasma lipids in patients with primary hypercholesterolemia
    • Apr;
    • Knopp RH, Gitter H, Truitt T, et al. Effects of ezetimibe, a new cholesterol absorption inhibitor, on plasma lipids in patients with primary hypercholesterolemia. Eur Heart J 2003 Apr; 24 (8): 729-41
    • (2003) Eur Heart J , vol.24 , Issue.8 , pp. 729-741
    • Knopp, R.H.1    Gitter, H.2    Truitt, T.3
  • 38
    • 0344490262 scopus 로고    scopus 로고
    • Efficacy and safety of ezetimibe coadministered with pravastatin in patients with primary hypercholesterolemia: A prospective, randomized, double-blind trial
    • Apr;
    • Melani L, Mills R, Hassman D, et al. Efficacy and safety of ezetimibe coadministered with pravastatin in patients with primary hypercholesterolemia: a prospective, randomized, double-blind trial. Eur Heart J 2003 Apr; 24 (8): 717-28
    • (2003) Eur Heart J , vol.24 , Issue.8 , pp. 717-728
    • Melani, L.1    Mills, R.2    Hassman, D.3
  • 39
    • 11844291388 scopus 로고    scopus 로고
    • A multicenter, randomized, double-blind, placebo-controlled, factorial design study to evaluate the lipid-altering efficacy and safety profile of the ezetimibe/simvastatin tablet compared with ezetimibe and simvastatin monotherapy in patients with primary hypercholesterolemia
    • Nov;
    • Bays HE, Ose L, Fraser N, et al. A multicenter, randomized, double-blind, placebo-controlled, factorial design study to evaluate the lipid-altering efficacy and safety profile of the ezetimibe/simvastatin tablet compared with ezetimibe and simvastatin monotherapy in patients with primary hypercholesterolemia. Clin Ther 2004 Nov; 26 (11): 1758-73
    • (2004) Clin Ther , vol.26 , Issue.11 , pp. 1758-1773
    • Bays, H.E.1    Ose, L.2    Fraser, N.3
  • 40
    • 0037132598 scopus 로고    scopus 로고
    • Ezetimibe coadministered with simvastatin in patients with primary hypercholesterolemia
    • Davidson MH, McGarry T, Bettis R, et al. Ezetimibe coadministered with simvastatin in patients with primary hypercholesterolemia. J Am Coll Cardiol 2002; 40 (12): 2125-34
    • (2002) J Am Coll Cardiol , vol.40 , Issue.12 , pp. 2125-2134
    • Davidson, M.H.1    McGarry, T.2    Bettis, R.3
  • 41
    • 2342574933 scopus 로고    scopus 로고
    • Ezetimibe Study Group. Efficacy and safety of ezetimibe coadministered with simvastatin in patients with primary hypercholesterolemia: A randomized, double-blind, placebo-controlled trial
    • May;
    • Goldberg AC, Sapre A, Liu J, et al., Ezetimibe Study Group. Efficacy and safety of ezetimibe coadministered with simvastatin in patients with primary hypercholesterolemia: a randomized, double-blind, placebo-controlled trial. Mayo Clin Proc 2004 May; 79 (5): 620-9
    • (2004) Mayo Clin Proc , vol.79 , Issue.5 , pp. 620-629
    • Goldberg, A.C.1    Sapre, A.2    Liu, J.3
  • 42
    • 8344257993 scopus 로고    scopus 로고
    • Cost-effectiveness of ezetimibe coadministration in statin-treated patients not at cholesterol goal: Application to Germany, Spain and Norway
    • Cook JR, Yin D, Alemao E, et al. Cost-effectiveness of ezetimibe coadministration in statin-treated patients not at cholesterol goal: application to Germany, Spain and Norway. Pharmacoeconomics 2004; 22 Suppl. 3: 49-61
    • (2004) Pharmacoeconomics , vol.22 , Issue.SUPPL. 3 , pp. 49-61
    • Cook, J.R.1    Yin, D.2    Alemao, E.3
  • 43
    • 33747154424 scopus 로고    scopus 로고
    • Cost effectiveness of adding ezetimibe to atorvastatin therapy in patients not at cholesterol treatment goal in Canada
    • Kohli M, Attard C, Lam A, et al. Cost effectiveness of adding ezetimibe to atorvastatin therapy in patients not at cholesterol treatment goal in Canada. Pharmacoeconomics 2006; 24 (8): 815-30
    • (2006) Pharmacoeconomics , vol.24 , Issue.8 , pp. 815-830
    • Kohli, M.1    Attard, C.2    Lam, A.3
  • 45
    • 33645225775 scopus 로고    scopus 로고
    • Lowering LDL-not only how low, but how long?
    • Brown M, Goldstein J. Lowering LDL-not only how low, but how long? Science 2006; 311: 1721-3
    • (2006) Science , vol.311 , pp. 1721-1723
    • Brown, M.1    Goldstein, J.2
  • 46
    • 0025086998 scopus 로고
    • Effect of partial ileal bypass surgery on mortality and morbidity from coronary heart disease in patients with hypercholesterolaemia. Report of the Program on the Surgical Control of Hyperlipidaemia (POSCH)
    • Buchwald H, Varco R, Matts J, et al. Effect of partial ileal bypass surgery on mortality and morbidity from coronary heart disease in patients with hypercholesterolaemia. Report of the Program on the Surgical Control of Hyperlipidaemia (POSCH). N Engl J Med 1990; 323: 946-55
    • (1990) N Engl J Med , vol.323 , pp. 946-955
    • Buchwald, H.1    Varco, R.2    Matts, J.3
  • 47
    • 11844296800 scopus 로고    scopus 로고
    • Efficacy and safety of high-density lipoprotein cholesterol -increasing compounds: A meta-analysis of randomized controlled trials
    • Birjmohus R, Hutten B, Kastelein JP, et al. Efficacy and safety of high-density lipoprotein cholesterol -increasing compounds: a meta-analysis of randomized controlled trials. J Am Coll Cardiol 2005; 45: 185-97
    • (2005) J Am Coll Cardiol , vol.45 , pp. 185-197
    • Birjmohus, R.1    Hutten, B.2    Kastelein, J.P.3
  • 48
    • 38949151617 scopus 로고    scopus 로고
    • Unreported cholesterol drug data released by company
    • Lenzer J. Unreported cholesterol drug data released by company. BMJ 2008; 336: 180-1
    • (2008) BMJ , vol.336 , pp. 180-181
    • Lenzer, J.1
  • 49
    • 84858748854 scopus 로고    scopus 로고
    • Public advisory:, Feb [online, Available from URL:, Accessed 2008 Feb 14
    • Public advisory: Health Canada endorsed important safety information on Ezetrol® (ezetimibe). Health Canada, 2005 Feb [online]. Available from URL: http://www.hc-sc.gc.ca/dhp-mps/alt-formats/hpfb-dgpsa/pdf/medeff/ ezetrol-hpc-cps-eng.pdf [Accessed 2008 Feb 14]
    • (2005) Health Canada endorsed important safety information on Ezetrol® (ezetimibe)


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.