Effect of the metabolic inhibitor, methimazole on the drug susceptibility of a triclabendazole-resistant isolate of Fasciola hepatica

Parasitology

Volumn 136, Issue 2, 2009, Pages 183-192

  Devine, C ^a   Brennan, G P ^a   Lanusse, C E ^b   Alvarez, L I ^b   Trudgett, A ^a   Hoey, E ^a   Fairweather, I ^a  

^a QUEEN'S UNIVERSITY BELFAST   (United Kingdom)

^b Campus Universitario (UNCPBA)   (Argentina)

Author keywords

Fasciola hepatica; Liver fluke; Methimazole; Scanning electron microscopy; Triclabendazole resistance

Indexed keywords

DIMETHYLANILINE MONOOXYGENASE; FLAVOPROTEIN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; THIAMAZOLE; TRICLABENDAZOLE; ANTIPLATYHELMINTIC AGENT; BENZIMIDAZOLE DERIVATIVE;

ANIMAL TISSUE; ANTIBIOTIC RESISTANCE; ARTICLE; BACTERIUM ISOLATE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFECT; DRUG METABOLISM; DRUG SENSITIVITY; ENZYME INHIBITION; ENZYME METABOLISM; FASCIOLA HEPATICA; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; SCANNING ELECTRON MICROSCOPY; ANIMAL; DRUG RESISTANCE; PHYSIOLOGY; SPRAGUE DAWLEY RAT; ULTRASTRUCTURE;

FASCIOLA HEPATICA;

ANIMALS; ANTIPLATYHELMINTIC AGENTS; BENZIMIDAZOLES; DRUG RESISTANCE; FASCIOLA HEPATICA; MALE; METHIMAZOLE; MICROSCOPY, ELECTRON, SCANNING; RATS; RATS, SPRAGUE-DAWLEY;

EID: 59449103376     PISSN: 00311820     EISSN: 14698161     Source Type: Journal    
DOI: 10.1017/S0031182008005222     Document Type: Article

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