메뉴 건너뛰기




Volumn 9, Issue 6, 2008, Pages 367-374

Transcriptional regulation of IRS5/DOK4 expression in non-small-cell lung cancer cells

Author keywords

Acetylation; Chromatin; DNA methylation; Histone

Indexed keywords

HISTONE DEACETYLASE INHIBITOR; INSULIN RECEPTOR SUBSTRATE 1; INSULIN RECEPTOR SUBSTRATE 5; TRICHOSTATIN A; UNCLASSIFIED DRUG;

EID: 59449101956     PISSN: 15257304     EISSN: None     Source Type: Journal    
DOI: 10.3816/CLC.2008.n.053     Document Type: Article
Times cited : (9)

References (45)
  • 1
    • 12344322710 scopus 로고    scopus 로고
    • Insulin receptor substrate proteins and diabetes
    • Lee YH, White MF. Insulin receptor substrate proteins and diabetes. Arch Pharm Res 2004; 27:361-70.
    • (2004) Arch Pharm Res , vol.27 , pp. 361-370
    • Lee, Y.H.1    White, M.F.2
  • 2
    • 0036460322 scopus 로고    scopus 로고
    • Absence of functional insulin receptor substrate-3 (IRS-3) gene in humans
    • Bjornholm M, He AR, Attersand A, et al. Absence of functional insulin receptor substrate-3 (IRS-3) gene in humans. Diabetologia 2002; 45:1697-702.
    • (2002) Diabetologia , vol.45 , pp. 1697-1702
    • Bjornholm, M.1    He, A.R.2    Attersand, A.3
  • 3
    • 0036710280 scopus 로고    scopus 로고
    • IRS proteins and the common path to diabetes
    • White MF. IRS proteins and the common path to diabetes. Am J Physiol Endocrinol Metab 2002; 283:E413-22.
    • (2002) Am J Physiol Endocrinol Metab , vol.283
    • White, M.F.1
  • 4
    • 0037816152 scopus 로고    scopus 로고
    • Two new substrates in insulin signaling, IRS5/DOK4 and IRS6/DOK5
    • Cai D, Dhe-Paganon S, Melendez PA, et al. Two new substrates in insulin signaling, IRS5/DOK4 and IRS6/DOK5. J Biol Chem 2003; 278:25323-30.
    • (2003) J Biol Chem , vol.278 , pp. 25323-25330
    • Cai, D.1    Dhe-Paganon, S.2    Melendez, P.A.3
  • 5
    • 0038713391 scopus 로고    scopus 로고
    • DOK4 and DOK5: New Dok-related genes expressed in human T cells
    • Favre C, Gerard A, Clauzier E, et al. DOK4 and DOK5: new Dok-related genes expressed in human T cells. Genes Immun 2003; 4:40-5.
    • (2003) Genes Immun , vol.4 , pp. 40-45
    • Favre, C.1    Gerard, A.2    Clauzier, E.3
  • 6
    • 34547110128 scopus 로고    scopus 로고
    • DOK4/IRS-5 expression is altered in clear cell renal cell carcinoma
    • Al-Sarraf N, Reiff JN, Hinrichsen J, et al. DOK4/IRS-5 expression is altered in clear cell renal cell carcinoma. Int J Cancer 2007; 121:992-8.
    • (2007) Int J Cancer , vol.121 , pp. 992-998
    • Al-Sarraf, N.1    Reiff, J.N.2    Hinrichsen, J.3
  • 7
    • 2442458850 scopus 로고    scopus 로고
    • Pleckstrin homology and phosphotyrosine- binding domain-dependent membrane association and tyrosine phosphorylation of Dok-4, an inhibitory adapter molecule expressed in epithelial cells
    • Bedirian A, Baldwin C, Abe J, et al. Pleckstrin homology and phosphotyrosine- binding domain-dependent membrane association and tyrosine phosphorylation of Dok-4, an inhibitory adapter molecule expressed in epithelial cells. J Biol Chem 2004; 279:19335-49.
    • (2004) J Biol Chem , vol.279 , pp. 19335-19349
    • Bedirian, A.1    Baldwin, C.2    Abe, J.3
  • 8
    • 22544444671 scopus 로고    scopus 로고
    • Mitochondrial Dok-4 recruits Src kinase and regulates NF-kappaB activation in endothelial cells
    • Itoh S, Lemay S, Osawa M, et al. Mitochondrial Dok-4 recruits Src kinase and regulates NF-kappaB activation in endothelial cells. J Biol Chem 2005; 280:26383-96.
    • (2005) J Biol Chem , vol.280 , pp. 26383-26396
    • Itoh, S.1    Lemay, S.2    Osawa, M.3
  • 9
    • 33846615910 scopus 로고    scopus 로고
    • Identification of Dok-4b, a Dok-4 splice variant with enhanced inhibitory properties
    • Baldwin C, Bedirian A, Li H, et al. Identification of Dok-4b, a Dok-4 splice variant with enhanced inhibitory properties. Biochem Biophys Res Commun 2007; 354:783-8.
    • (2007) Biochem Biophys Res Commun , vol.354 , pp. 783-788
    • Baldwin, C.1    Bedirian, A.2    Li, H.3
  • 10
    • 33751173659 scopus 로고    scopus 로고
    • The IGF-1 network in lung carcinoma therapeutics
    • Karamouzis MV, Papavassiliou AG. The IGF-1 network in lung carcinoma therapeutics. Trends Mol Med 2006; 12:595-602.
    • (2006) Trends Mol Med , vol.12 , pp. 595-602
    • Karamouzis, M.V.1    Papavassiliou, A.G.2
  • 11
    • 34548018304 scopus 로고    scopus 로고
    • The insulin-like growth factor 1 receptor in cancer: Old focus, new future
    • Hartog H, Wesseling J, Boezen HM, et al. The insulin-like growth factor 1 receptor in cancer: old focus, new future. Eur J Cancer 2007; 43:1895-904.
    • (2007) Eur J Cancer , vol.43 , pp. 1895-1904
    • Hartog, H.1    Wesseling, J.2    Boezen, H.M.3
  • 12
    • 34249049000 scopus 로고    scopus 로고
    • Implication of the insulin-like growth factor- IR pathway in the resistance of non-small cell lung cancer cells to treatment with gefitinib
    • Morgillo F, Kim WY, Kim ES, et al. Implication of the insulin-like growth factor- IR pathway in the resistance of non-small cell lung cancer cells to treatment with gefitinib. Clin Cancer Res 2007; 13:2795-803.
    • (2007) Clin Cancer Res , vol.13 , pp. 2795-2803
    • Morgillo, F.1    Kim, W.Y.2    Kim, E.S.3
  • 13
    • 33750571170 scopus 로고    scopus 로고
    • Heterodimerization of insulin-like growth factor receptor/epidermal growth factor receptor and induction of survivin expression counteract the antitumor action of erlotinib
    • Morgillo F, Woo JK, Kim ES, et al. Heterodimerization of insulin-like growth factor receptor/epidermal growth factor receptor and induction of survivin expression counteract the antitumor action of erlotinib. Cancer Res 2006; 66:10100-11.
    • (2006) Cancer Res , vol.66 , pp. 10100-10111
    • Morgillo, F.1    Woo, J.K.2    Kim, E.S.3
  • 14
    • 0346095208 scopus 로고    scopus 로고
    • The insulin-like growth factors and insulin-signalling systems: An appealing target for breast cancer therapy?
    • Gray SG, Stenfeldt Mathiasen I, De Meyts P. The insulin-like growth factors and insulin-signalling systems: an appealing target for breast cancer therapy? Horm Metab Res 2003; 35:857-71.
    • (2003) Horm Metab Res , vol.35 , pp. 857-871
    • Gray, S.G.1    Stenfeldt Mathiasen, I.2    De Meyts, P.3
  • 15
    • 5644280150 scopus 로고    scopus 로고
    • Selective activation of insulin receptor sub- strate-1 and -2 in pleural mesothelioma cells: Association with distinct malignant phenotypes
    • Hoang CD, Zhang X, Scott PD, et al. Selective activation of insulin receptor sub- strate-1 and -2 in pleural mesothelioma cells: association with distinct malignant phenotypes. Cancer Res 2004; 64:7479-85.
    • (2004) Cancer Res , vol.64 , pp. 7479-7485
    • Hoang, C.D.1    Zhang, X.2    Scott, P.D.3
  • 16
    • 26044443543 scopus 로고    scopus 로고
    • Expression of the insulin receptor substrate 1 in primary tumors and lymph node metastases in breast cancer: Correlations with Bcl-xL and Bax proteins
    • Koda M, Sulkowska M, Kanczuga-Koda L, et al. Expression of the insulin receptor substrate 1 in primary tumors and lymph node metastases in breast cancer: correlations with Bcl-xL and Bax proteins. Neoplasma 2005; 52:361-3.
    • (2005) Neoplasma , vol.52 , pp. 361-363
    • Koda, M.1    Sulkowska, M.2    Kanczuga-Koda, L.3
  • 17
    • 24044536590 scopus 로고    scopus 로고
    • Overexpression of insulin receptor substrate-2 in human and murine hepatocellular carcinoma
    • Boissan M, Beurel E, Wendum D, et al. Overexpression of insulin receptor substrate-2 in human and murine hepatocellular carcinoma. Am J Pathol 2005; 167:869-77.
    • (2005) Am J Pathol , vol.167 , pp. 869-877
    • Boissan, M.1    Beurel, E.2    Wendum, D.3
  • 18
    • 20444438450 scopus 로고    scopus 로고
    • Expression of insulin receptor substrate 1 in primary breast cancer and lymph node metastases
    • Koda M, Sulkowska M, Kanczuga-Koda L, et al. Expression of insulin receptor substrate 1 in primary breast cancer and lymph node metastases. J Clin Pathol 2005; 58:645-9.
    • (2005) J Clin Pathol , vol.58 , pp. 645-649
    • Koda, M.1    Sulkowska, M.2    Kanczuga-Koda, L.3
  • 19
    • 33744927684 scopus 로고    scopus 로고
    • Epidermal growth factor induces insulin receptor substrate-2 in breast cancer cells via c-Jun NH(2)-terminal kinase/activator protein-1 signaling to regulate cell migration
    • Cui X, Kim HJ, Kuiatse I, et al. Epidermal growth factor induces insulin receptor substrate-2 in breast cancer cells via c-Jun NH(2)-terminal kinase/activator protein-1 signaling to regulate cell migration. Cancer Res 2006; 66:5304-13.
    • (2006) Cancer Res , vol.66 , pp. 5304-5313
    • Cui, X.1    Kim, H.J.2    Kuiatse, I.3
  • 20
    • 27544501420 scopus 로고    scopus 로고
    • Up-regulation of insulin-like growth factor axis components in human primary prostate cancer correlates with tumor grade
    • Liao Y, Abel U, Grobholz R, et al. Up-regulation of insulin-like growth factor axis components in human primary prostate cancer correlates with tumor grade. Hum Pathol 2005; 36:1186-96.
    • (2005) Hum Pathol , vol.36 , pp. 1186-1196
    • Liao, Y.1    Abel, U.2    Grobholz, R.3
  • 21
    • 34047203885 scopus 로고    scopus 로고
    • Clinical significance of insulin receptor substrate-I down-regulation in non-small cell lung cancer
    • Han CH, Cho JY, Moon JT, et al. Clinical significance of insulin receptor substrate-I down-regulation in non-small cell lung cancer. Oncol Rep 2006; 16:1205-10.
    • (2006) Oncol Rep , vol.16 , pp. 1205-1210
    • Han, C.H.1    Cho, J.Y.2    Moon, J.T.3
  • 22
    • 0036196081 scopus 로고    scopus 로고
    • Acute intensive insulin therapy exacerbates diabetic blood-retinal barrier breakdown via hypoxia-inducible factor-1alpha and VEGF
    • Poulaki V, Qin W, Joussen AM, et al. Acute intensive insulin therapy exacerbates diabetic blood-retinal barrier breakdown via hypoxia-inducible factor-1alpha and VEGF. J Clin Invest 2002; 109:805-15.
    • (2002) J Clin Invest , vol.109 , pp. 805-815
    • Poulaki, V.1    Qin, W.2    Joussen, A.M.3
  • 23
    • 0034647770 scopus 로고    scopus 로고
    • Insulin and insulin-like growth factor-I induce vascular endothelial growth factor mRNA expression via different signaling pathways
    • Miele C, Rochford JJ, Filippa N, et al. Insulin and insulin-like growth factor-I induce vascular endothelial growth factor mRNA expression via different signaling pathways. J Biol Chem 2000; 275:21695-702.
    • (2000) J Biol Chem , vol.275 , pp. 21695-21702
    • Miele, C.1    Rochford, J.J.2    Filippa, N.3
  • 24
    • 0035140432 scopus 로고    scopus 로고
    • Insulin up-regulates vascular endothelial growth factor and stabilizes its messengers in endometrial adenocarcinoma cells
    • Bermont L, Lamielle F, Lorchel F, et al. Insulin up-regulates vascular endothelial growth factor and stabilizes its messengers in endometrial adenocarcinoma cells. J Clin Endocrinol Metab 2001; 86:363-8.
    • (2001) J Clin Endocrinol Metab , vol.86 , pp. 363-368
    • Bermont, L.1    Lamielle, F.2    Lorchel, F.3
  • 25
    • 33745303045 scopus 로고    scopus 로고
    • Hypoxia signalling in cancer and approaches to enforce tumour regression
    • Pouyssegur J, Dayan F, Mazure NM. Hypoxia signalling in cancer and approaches to enforce tumour regression. Nature 2006; 441:437-43.
    • (2006) Nature , vol.441 , pp. 437-443
    • Pouyssegur, J.1    Dayan, F.2    Mazure, N.M.3
  • 26
    • 0041355277 scopus 로고    scopus 로고
    • Characterization of multiple signaling pathways of insulin in the regulation of vascular endothelial growth factor expression in vascular cells and angiogenesis
    • Jiang ZY, He Z, King BL, et al. Characterization of multiple signaling pathways of insulin in the regulation of vascular endothelial growth factor expression in vascular cells and angiogenesis. J Biol Chem 2003; 278:31964-71.
    • (2003) J Biol Chem , vol.278 , pp. 31964-31971
    • Jiang, Z.Y.1    He, Z.2    King, B.L.3
  • 27
    • 0035939661 scopus 로고    scopus 로고
    • Novel p62dok family members, dok-4 and dok-5, are substrates of the c-Ret receptor tyrosine kinase and mediate neuronal differentiation
    • Grimm J, Sachs M, Britsch S, et al. Novel p62dok family members, dok-4 and dok-5, are substrates of the c-Ret receptor tyrosine kinase and mediate neuronal differentiation. J Cell Biol 2001; 154:345-54.
    • (2001) J Cell Biol , vol.154 , pp. 345-354
    • Grimm, J.1    Sachs, M.2    Britsch, S.3
  • 28
    • 24944496184 scopus 로고    scopus 로고
    • Role of histone and transcription factor acetylation in diabetes pathogenesis
    • Gray SG, De Meyts P. Role of histone and transcription factor acetylation in diabetes pathogenesis. Diabetes Metab Res Rev 2005; 21:416-33.
    • (2005) Diabetes Metab Res Rev , vol.21 , pp. 416-433
    • Gray, S.G.1    De Meyts, P.2
  • 29
    • 0035877007 scopus 로고    scopus 로고
    • Processing of immunosuppressive pro-TGF-beta 1,2 by human glioblastoma cells involves cytoplasmic and secreted furin-like proteases
    • Leitlein J, Aulwurm S, Waltereit R, et al. Processing of immunosuppressive pro-TGF-beta 1,2 by human glioblastoma cells involves cytoplasmic and secreted furin-like proteases. J Immunol 2001; 166:7238-43.
    • (2001) J Immunol , vol.166 , pp. 7238-7243
    • Leitlein, J.1    Aulwurm, S.2    Waltereit, R.3
  • 30
    • 0036856355 scopus 로고    scopus 로고
    • MethPrimer: Designing primers for methylation PCRs
    • Li LC, Dahiya R. MethPrimer: designing primers for methylation PCRs. Bioinformatics 2002; 18:1427-31.
    • (2002) Bioinformatics , vol.18 , pp. 1427-1431
    • Li, L.C.1    Dahiya, R.2
  • 31
    • 85047698762 scopus 로고    scopus 로고
    • Frequent and histological type-specific inactivation of 14-3-3sigma in human lung cancers
    • Osada H, Tatematsu Y, Yatabe Y, et al. Frequent and histological type-specific inactivation of 14-3-3sigma in human lung cancers. Oncogene 2002; 21:2418-24.
    • (2002) Oncogene , vol.21 , pp. 2418-2424
    • Osada, H.1    Tatematsu, Y.2    Yatabe, Y.3
  • 32
    • 22844443822 scopus 로고    scopus 로고
    • Altered expression of members of the IGF-axis in clear cell renal cell carcinoma
    • Takahashi M, Papavero V, Yuhas J, et al. Altered expression of members of the IGF-axis in clear cell renal cell carcinoma. Int J Oncol 2005; 26:923-31.
    • (2005) Int J Oncol , vol.26 , pp. 923-931
    • Takahashi, M.1    Papavero, V.2    Yuhas, J.3
  • 33
    • 7644237126 scopus 로고    scopus 로고
    • Involvement of insulin receptor substrate 2 in mammary tumor metastasis
    • Nagle JA, Ma Z, Byrne MA, et al. Involvement of insulin receptor substrate 2 in mammary tumor metastasis. Mol Cell Biol 2004; 24:9726-35.
    • (2004) Mol Cell Biol , vol.24 , pp. 9726-9735
    • Nagle, J.A.1    Ma, Z.2    Byrne, M.A.3
  • 34
    • 0036828097 scopus 로고    scopus 로고
    • Constitutive activation of insulin receptor substrate 1 is a frequent event in human tumors: Therapeutic implications
    • Chang Q, Li Y, White MF, et al. Constitutive activation of insulin receptor substrate 1 is a frequent event in human tumors: therapeutic implications. Cancer Res 2002; 62:6035-8.
    • (2002) Cancer Res , vol.62 , pp. 6035-6038
    • Chang, Q.1    Li, Y.2    White, M.F.3
  • 35
    • 33748122556 scopus 로고    scopus 로고
    • Cancer-linked DNA hypomethylation and its relationship to hypermethylation
    • Ehrlich M. Cancer-linked DNA hypomethylation and its relationship to hypermethylation. Curr Top Microbiol Immunol 2006; 310:251-74.
    • (2006) Curr Top Microbiol Immunol , vol.310 , pp. 251-274
    • Ehrlich, M.1
  • 36
    • 33644846509 scopus 로고    scopus 로고
    • Epigenetic gene silencing in cancer - a mechanism for early oncogenic pathway addiction?
    • Baylin SB, Ohm JE. Epigenetic gene silencing in cancer - a mechanism for early oncogenic pathway addiction? Nat Rev Cancer 2006; 6:107-16.
    • (2006) Nat Rev Cancer , vol.6 , pp. 107-116
    • Baylin, S.B.1    Ohm, J.E.2
  • 37
    • 0038204415 scopus 로고    scopus 로고
    • The diverse functions of histone acetyltransferase complexes
    • Carrozza MJ, Utley RT, Workman JL, et al. The diverse functions of histone acetyltransferase complexes. Trends Genet 2003; 19:321-9.
    • (2003) Trends Genet , vol.19 , pp. 321-329
    • Carrozza, M.J.1    Utley, R.T.2    Workman, J.L.3
  • 38
    • 0035862199 scopus 로고    scopus 로고
    • The human histone deacetylase family
    • Gray SG, Ekstrom TJ. The human histone deacetylase family. Exp Cell Res 2001; 262:75-83.
    • (2001) Exp Cell Res , vol.262 , pp. 75-83
    • Gray, S.G.1    Ekstrom, T.J.2
  • 39
    • 3042816190 scopus 로고    scopus 로고
    • Hypoxia-inducible factor-1 alpha in non small cell lung cancer: Relation to growth factor, protease and apoptosis pathways
    • Swinson DE, Jones JL, Cox G, et al. Hypoxia-inducible factor-1 alpha in non small cell lung cancer: relation to growth factor, protease and apoptosis pathways. Int J Cancer 2004; 111:43-50.
    • (2004) Int J Cancer , vol.111 , pp. 43-50
    • Swinson, D.E.1    Jones, J.L.2    Cox, G.3
  • 40
    • 0037315252 scopus 로고    scopus 로고
    • Carbonic anhydrase IX expression, a novel surrogate marker of tumor hypoxia, is associated with a poor prognosis in non-small-cell lung cancer
    • Swinson DE, Jones JL, Richardson D, et al. Carbonic anhydrase IX expression, a novel surrogate marker of tumor hypoxia, is associated with a poor prognosis in non-small-cell lung cancer. J Clin Oncol 2003; 21:473-82.
    • (2003) J Clin Oncol , vol.21 , pp. 473-482
    • Swinson, D.E.1    Jones, J.L.2    Richardson, D.3
  • 41
    • 33744969828 scopus 로고    scopus 로고
    • Energy deregulation: Licensing tumors to grow
    • Garber K. Energy deregulation: licensing tumors to grow. Science 2006; 312:1158-9.
    • (2006) Science , vol.312 , pp. 1158-1159
    • Garber, K.1
  • 42
    • 27544483703 scopus 로고    scopus 로고
    • Regulation of glycolysis-role of insulin
    • Wu C, Khan SA, Lange AJ. Regulation of glycolysis-role of insulin. Exp Gerontol 2005; 40:894-9.
    • (2005) Exp Gerontol , vol.40 , pp. 894-899
    • Wu, C.1    Khan, S.A.2    Lange, A.J.3
  • 43
    • 0026631259 scopus 로고
    • Insulin, growth factors, and cancer cell energy metabolism: An hypothesis on oncogene action
    • Golshani S. Insulin, growth factors, and cancer cell energy metabolism: an hypothesis on oncogene action. Biochem Med Metab Biol 1992; 47:108-15.
    • (1992) Biochem Med Metab Biol , vol.47 , pp. 108-115
    • Golshani, S.1
  • 44
    • 33748308772 scopus 로고    scopus 로고
    • Dok-4 regulates GDNF-dependent neurite outgrowth through downstream activation of Rap1 and mitogen-activated protein kinase
    • Uchida M, Enomoto A, Fukuda T, et al. Dok-4 regulates GDNF-dependent neurite outgrowth through downstream activation of Rap1 and mitogen-activated protein kinase. J Cell Sci 2006; 119:3067-77.
    • (2006) J Cell Sci , vol.119 , pp. 3067-3077
    • Uchida, M.1    Enomoto, A.2    Fukuda, T.3
  • 45
    • 0024536716 scopus 로고
    • elk, tissue-specific ets-related genes on chromosomes X and 14 near translocation breakpoints
    • Rao VN, Huebner K, Isobe M, et al. elk, tissue-specific ets-related genes on chromosomes X and 14 near translocation breakpoints. Science 1989; 244:66-70.
    • (1989) Science , vol.244 , pp. 66-70
    • Rao, V.N.1    Huebner, K.2    Isobe, M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.