메뉴 건너뛰기




Volumn 16, Issue 2, 2009, Pages 515-523

Chemoprotective effects of curcuma aromatica on esophageal carcinogenesis

Author keywords

[No Author keywords available]

Indexed keywords

8 HYDROXYDEOXYGUANOSINE; ANTINEOPLASTIC AGENT; CURCUMA AROMATICA EXTRACT; MANGANESE SUPEROXIDE DISMUTASE; PLANT EXTRACT; THIOBARBITURIC ACID REACTIVE SUBSTANCE; UNCLASSIFIED DRUG;

EID: 59449101272     PISSN: 10689265     EISSN: 15344681     Source Type: Journal    
DOI: 10.1245/s10434-008-0228-0     Document Type: Article
Times cited : (44)

References (61)
  • 2
    • 33645880108 scopus 로고    scopus 로고
    • A novel external esophageal perfusion model for reflux esophageal injury
    • Y Li JM Wo S Ellis MB Ray W Jones RC Martin 2006 A novel external esophageal perfusion model for reflux esophageal injury Dig Dis Sci. 51 527 32
    • (2006) Dig Dis Sci. , vol.51 , pp. 527-32
    • Li, Y.1    Wo, J.M.2    Ellis, S.3    Ray, M.B.4    Jones, W.5    Martin, R.C.6
  • 3
    • 33751020567 scopus 로고    scopus 로고
    • Morphological transformation in esophageal submucosa by bone marrow cells: Esophageal implantation under external esophageal perfusion
    • Y Li JM Wo S Ellis MB Ray W Jones RC Martin 2006 Morphological transformation in esophageal submucosa by bone marrow cells: esophageal implantation under external esophageal perfusion Stem Cells Dev. 15 697 705
    • (2006) Stem Cells Dev. , vol.15 , pp. 697-705
    • Li, Y.1    Wo, J.M.2    Ellis, S.3    Ray, M.B.4    Jones, W.5    Martin, R.C.6
  • 4
    • 34250904161 scopus 로고    scopus 로고
    • Alterations in manganese superoxide dismutase expression in the progression from reflux esophagitis to esophageal adenocarcinoma
    • Y Li JM Wo RR Su MB Ray RC Martin 2007 Alterations in manganese superoxide dismutase expression in the progression from reflux esophagitis to esophageal adenocarcinoma Ann Surg Oncol. 14 2045 55
    • (2007) Ann Surg Oncol. , vol.14 , pp. 2045-55
    • Li, Y.1    Wo, J.M.2    Su, R.R.3    Ray, M.B.4    Martin, R.C.5
  • 5
    • 0034456207 scopus 로고    scopus 로고
    • Oxidative stress, antioxidant defenses, and damage removal, repair, and replacement systems
    • KJA Davies 2000 Oxidative stress, antioxidant defenses, and damage removal, repair, and replacement systems Iubmb Life. 50 279 89
    • (2000) Iubmb Life. , vol.50 , pp. 279-89
    • Davies, K.J.A.1
  • 6
    • 0034908033 scopus 로고    scopus 로고
    • Esophageal adenocarcinoma: A review and perspectives on the mechanism of carcinogenesis and chemoprevention
    • XX Chen CS Yang 2001 Esophageal adenocarcinoma: a review and perspectives on the mechanism of carcinogenesis and chemoprevention Carcinogenesis. 22 1119 29
    • (2001) Carcinogenesis. , vol.22 , pp. 1119-29
    • Chen, X.X.1    Yang, C.S.2
  • 7
    • 0642312184 scopus 로고    scopus 로고
    • Advances in the clinical application and experimental study of Curcuma zedoaria oil preparations
    • B Li N Liang 2003 Advances in the clinical application and experimental study of Curcuma zedoaria oil preparations Zhong Yao Cai. 26 68 71
    • (2003) Zhong Yao Cai. , vol.26 , pp. 68-71
    • Li, B.1    Liang, N.2
  • 8
    • 0345540638 scopus 로고    scopus 로고
    • Oral administration of a turmeric extract inhibits LDL oxidation and has hypocholesterolemic effects in rabbits with experimental atherosclerosis
    • MC Ramirez-Tortosa MD Mesa MC Aguilera JL Quiles L Baro CL Ramirez-Tortosa 1999 Oral administration of a turmeric extract inhibits LDL oxidation and has hypocholesterolemic effects in rabbits with experimental atherosclerosis Atherosclerosis. 147 371 8
    • (1999) Atherosclerosis. , vol.147 , pp. 371-8
    • Ramirez-Tortosa, M.C.1    Mesa, M.D.2    Aguilera, M.C.3    Quiles, J.L.4    Baro, L.5    Ramirez-Tortosa, C.L.6
  • 11
    • 0034693376 scopus 로고    scopus 로고
    • An hydroalcoholic extract of Curcuma longa lowers the apo B/apo A ratio. Implications for atherogenesis prevention
    • A Ramirez-Bosca A Soler MA Carrion J Diaz-Alperi A Bernd C Quintanilla 2000 An hydroalcoholic extract of Curcuma longa lowers the apo B/apo A ratio. Implications for atherogenesis prevention Mech Ageing Dev. 119 41 7
    • (2000) Mech Ageing Dev. , vol.119 , pp. 41-7
    • Ramirez-Bosca, A.1    Soler, A.2    Carrion, M.A.3    Diaz-Alperi, J.4    Bernd, A.5    Quintanilla, C.6
  • 12
    • 0031716184 scopus 로고    scopus 로고
    • Curcumin induces a p53-dependent apoptosis in human basal cell carcinoma cells
    • SH Jee SC Shen CR Tseng HC Chiu ML Kuo 1998 Curcumin induces a p53-dependent apoptosis in human basal cell carcinoma cells J Invest Dermatol. 111 656 61
    • (1998) J Invest Dermatol. , vol.111 , pp. 656-61
    • Jee, S.H.1    Shen, S.C.2    Tseng, C.R.3    Chiu, H.C.4    Kuo, M.L.5
  • 13
    • 0028073507 scopus 로고
    • Inhibitory effects of dietary curcumin on forestomach, duodenal, and colon carcinogenesis in mice
    • MT Huang YR Lou W Ma HL Newmark KR Reuhl AH Conney 1994 Inhibitory effects of dietary curcumin on forestomach, duodenal, and colon carcinogenesis in mice Cancer Res. 54 5841 7
    • (1994) Cancer Res. , vol.54 , pp. 5841-7
    • Huang, M.T.1    Lou, Y.R.2    Ma, W.3    Newmark, H.L.4    Reuhl, K.R.5    Conney, A.H.6
  • 18
    • 34250904161 scopus 로고    scopus 로고
    • Alterations in manganese superoxide dismutase expression in the progression from reflux esophagitis to esophageal adenocarcinoma
    • Y Li JM Wo RR Su MB Ray RC Martin 2007 Alterations in manganese superoxide dismutase expression in the progression from reflux esophagitis to esophageal adenocarcinoma Ann Surg Oncol. 14 2045 55
    • (2007) Ann Surg Oncol. , vol.14 , pp. 2045-55
    • Li, Y.1    Wo, J.M.2    Su, R.R.3    Ray, M.B.4    Martin, R.C.5
  • 19
    • 0014733323 scopus 로고
    • Histological consequences of gastroesophageal reflux in man
    • F Ismail-Beigi PF Horton CE Pope 1970 Histological consequences of gastroesophageal reflux in man Gastroenterology. 58 163 74
    • (1970) Gastroenterology. , vol.58 , pp. 163-74
    • Ismail-Beigi, F.1    Horton, P.F.2    Pope, C.E.3
  • 21
    • 33645880108 scopus 로고    scopus 로고
    • A novel external esophageal perfusion model for reflux esophageal injury
    • Y Li JM Wo S Ellis MB Ray W Jones RC Martin 2006 A novel external esophageal perfusion model for reflux esophageal injury Dig Dis Sci. 51 527 32
    • (2006) Dig Dis Sci. , vol.51 , pp. 527-32
    • Li, Y.1    Wo, J.M.2    Ellis, S.3    Ray, M.B.4    Jones, W.5    Martin, R.C.6
  • 22
    • 34250904161 scopus 로고    scopus 로고
    • Alterations in manganese superoxide dismutase expression in the progression from reflux esophagitis to esophageal adenocarcinoma
    • Y Li JM Wo RR Su MB Ray RC Martin 2007 Alterations in manganese superoxide dismutase expression in the progression from reflux esophagitis to esophageal adenocarcinoma Ann Surg Oncol. 14 2045 55
    • (2007) Ann Surg Oncol. , vol.14 , pp. 2045-55
    • Li, Y.1    Wo, J.M.2    Su, R.R.3    Ray, M.B.4    Martin, R.C.5
  • 23
    • 33745933744 scopus 로고    scopus 로고
    • Down-regulation of prostaglandin e2 by curcumin is correlated with inhibition of cell growth and induction of apoptosis in human colon carcinoma cell lines
    • S Lev-Ari Y Maimon L Strier D Kazanov N Arber 2006 Down-regulation of prostaglandin e2 by curcumin is correlated with inhibition of cell growth and induction of apoptosis in human colon carcinoma cell lines J Soc Integr Oncol. 4 21 6
    • (2006) J Soc Integr Oncol. , vol.4 , pp. 21-6
    • Lev-Ari, S.1    Maimon, Y.2    Strier, L.3    Kazanov, D.4    Arber, N.5
  • 24
    • 1642626324 scopus 로고
    • Experimental research on the pharmacology of Curcuma aromatica volatile oil
    • JH Shi CZ Li DL Liu 1981 Experimental research on the pharmacology of Curcuma aromatica volatile oil Zhong yao Tong bao 6 36 8
    • (1981) Zhong Yao Tong Bao , vol.6 , pp. 36-8
    • Shi, J.H.1    Li, C.Z.2    Liu, D.L.3
  • 25
    • 0000257636 scopus 로고
    • Curcumenone, curcumanolide A and curcumanolide B, three sesquiterpenoids from Curcuma zedoaria
    • Y Shiobara Y Asakawa M Kodama K Yasuda T Takemoto 1985 Curcumenone, curcumanolide A and curcumanolide B, three sesquiterpenoids from Curcuma zedoaria Phytochemistry. 24 2629 33
    • (1985) Phytochemistry. , vol.24 , pp. 2629-33
    • Shiobara, Y.1    Asakawa, Y.2    Kodama, M.3    Yasuda, K.4    Takemoto, T.5
  • 26
    • 34548591260 scopus 로고    scopus 로고
    • Study on the volatile oil by SFE-CO, from crude and processed rhizoma atractylodis by GC-MS
    • LY Xu LQ Tian K Li SW Chen Y Mao 2007 Study on the volatile oil by SFE-CO, from crude and processed rhizoma atractylodis by GC-MS Zhong Yao Cai. 30 16 20
    • (2007) Zhong Yao Cai. , vol.30 , pp. 16-20
    • Xu, L.Y.1    Tian, L.Q.2    Li, K.3    Chen, S.W.4    Mao, Y.5
  • 27
    • 0026502187 scopus 로고
    • Analysis of the essential oils of five Curcuma species
    • JH Zwaving R Bos 1991 Analysis of the essential oils of five Curcuma species Flavour Fragrance J. 7 19 22
    • (1991) Flavour Fragrance J. , vol.7 , pp. 19-22
    • Zwaving, J.H.1    Bos, R.2
  • 28
    • 0037236792 scopus 로고    scopus 로고
    • Anticancer potential of curcumin: Preclinical and clinical studies
    • BB Aggarwal A Kumar AC Bharti 2003 Anticancer potential of curcumin: preclinical and clinical studies Anticancer Res. 23 363 98
    • (2003) Anticancer Res. , vol.23 , pp. 363-98
    • Aggarwal, B.B.1    Kumar, A.2    Bharti, A.C.3
  • 29
    • 0034132135 scopus 로고    scopus 로고
    • Therapeutic efficacy of microsphere-entrapped Curcuma aromatica oil infused via hepatic artery against transplanted hepatoma in rats
    • W Wu R Deng Y Ou 2000 Therapeutic efficacy of microsphere-entrapped Curcuma aromatica oil infused via hepatic artery against transplanted hepatoma in rats Zhonghua Gan Zang Bing Za Zhi. 8 24 6
    • (2000) Zhonghua Gan Zang Bing Za Zhi. , vol.8 , pp. 24-6
    • Wu, W.1    Deng, R.2    Ou, Y.3
  • 31
    • 0022024499 scopus 로고
    • Anti-inflammatory effect of the volatile oil from Curcuma aromatica
    • CZ Li 1985 Anti-inflammatory effect of the volatile oil from Curcuma aromatica Zhong Yao Tong Bao. 10 38 40
    • (1985) Zhong Yao Tong Bao. , vol.10 , pp. 38-40
    • Li, C.Z.1
  • 32
    • 33745683901 scopus 로고    scopus 로고
    • Comparison of anti-inflammatory activities of six Curcuma rhizomes: A possible curcuminoid-independent pathway mediated by Curcuma phaeocaulis extract
    • C Tohda N Nakayama F Hatanaka K Komatsu 2006 Comparison of anti-inflammatory activities of six Curcuma rhizomes: a possible curcuminoid-independent pathway mediated by Curcuma phaeocaulis extract Evid Based Complement Alternat Med. 3 255 60
    • (2006) Evid Based Complement Alternat Med. , vol.3 , pp. 255-60
    • Tohda, C.1    Nakayama, N.2    Hatanaka, F.3    Komatsu, K.4
  • 34
    • 33847071264 scopus 로고    scopus 로고
    • Suppression by Curcuma comosa Roxb. of pro-inflammatory cytokine secretion in phorbol-12-myristate-13-acetate stimulated human mononuclear cells
    • A Sodsai P Piyachaturawat S Sophasan A Suksamrarn M Vongsakul 2007 Suppression by Curcuma comosa Roxb. of pro-inflammatory cytokine secretion in phorbol-12-myristate-13-acetate stimulated human mononuclear cells Int Immunopharmacol 7 524 31
    • (2007) Int Immunopharmacol , vol.7 , pp. 524-31
    • Sodsai, A.1    Piyachaturawat, P.2    Sophasan, S.3    Suksamrarn, A.4    Vongsakul, M.5
  • 35
    • 33750930911 scopus 로고    scopus 로고
    • Efficacy and mechanism of action of turmeric supplements in the treatment of experimental arthritis.
    • Funk JL, Frye JB, Oyarzo JN, Kuscuoglu N, Wilson J, McCaffrey G, et al. Efficacy and mechanism of action of turmeric supplements in the treatment of experimental arthritis. Arthritis Rheum. 2006;543452-64.
    • (2006) Arthritis Rheum. , vol.543 , pp. 452-64
    • Funk, J.L.1    Frye, J.B.2    Oyarzo, J.N.3    Kuscuoglu, N.4    Wilson, J.5    McCaffrey, G.6
  • 36
    • 28544452918 scopus 로고    scopus 로고
    • Antioxidant and antiinflammatory activities of xanthorrhizol in hippocampal neurons and primary cultured microglia
    • CS Lim DQ Jin H Mok SJ Oh JU Lee JK Hwang 2005 Antioxidant and antiinflammatory activities of xanthorrhizol in hippocampal neurons and primary cultured microglia J Neurosci Res. 82 831 8
    • (2005) J Neurosci Res. , vol.82 , pp. 831-8
    • Lim, C.S.1    Jin, D.Q.2    Mok, H.3    Oh, S.J.4    Lee, J.U.5    Hwang, J.K.6
  • 39
    • 0034103707 scopus 로고    scopus 로고
    • Association between body mass index and adenocarcinoma of the esophagus and gastric cardia
    • SD Li S Mobarhan 2000 Association between body mass index and adenocarcinoma of the esophagus and gastric cardia Nutr Rev. 58 54 6
    • (2000) Nutr Rev. , vol.58 , pp. 54-6
    • Li, S.D.1    Mobarhan, S.2
  • 40
    • 0032823595 scopus 로고    scopus 로고
    • An esophagogastroduodenal anastomosis model for esophageal adenocarcinogenesis in rats and enhancement by iron overload
    • XX Chen GY Yang WY Ding F Bondoc SK Curtis CS Yang 1999 An esophagogastroduodenal anastomosis model for esophageal adenocarcinogenesis in rats and enhancement by iron overload Carcinogenesis. 20 1801 7
    • (1999) Carcinogenesis. , vol.20 , pp. 1801-7
    • Chen, X.X.1    Yang, G.Y.2    Ding, W.Y.3    Bondoc, F.4    Curtis, S.K.5    Yang, C.S.6
  • 42
    • 0033853253 scopus 로고    scopus 로고
    • Effects of vitamin e and selenium supplementation on esophageal adenocarcinogenesis in a surgical model with rats
    • XX Chen SS Mikhail YW Ding GY Yang F Bondoc CS Yang 2000 Effects of vitamin E and selenium supplementation on esophageal adenocarcinogenesis in a surgical model with rats Carcinogenesis. 21 1531 6
    • (2000) Carcinogenesis. , vol.21 , pp. 1531-6
    • Chen, X.X.1    Mikhail, S.S.2    Ding, Y.W.3    Yang, G.Y.4    Bondoc, F.5    Yang, C.S.6
  • 43
    • 0034908033 scopus 로고    scopus 로고
    • Esophageal adenocarcinoma: A review and perspectives on the mechanism of carcinogenesis and chemoprevention
    • XX Chen CS Yang 2001 Esophageal adenocarcinoma: a review and perspectives on the mechanism of carcinogenesis and chemoprevention Carcinogenesis. 22 1119 29
    • (2001) Carcinogenesis. , vol.22 , pp. 1119-29
    • Chen, X.X.1    Yang, C.S.2
  • 45
    • 0031588174 scopus 로고    scopus 로고
    • Increasing incidence of Barrett's oesophagus: Education, enthusiasm, or epidemiology?
    • AT Prach TA MacDonald DA Hopwood DA Johnston 1997 Increasing incidence of Barrett's oesophagus: education, enthusiasm, or epidemiology? Lancet. 350 933
    • (1997) Lancet. , vol.350 , pp. 933
    • Prach, A.T.1    MacDonald, T.A.2    Hopwood, D.A.3    Johnston, D.A.4
  • 46
    • 0037236792 scopus 로고    scopus 로고
    • Anticancer potential of curcumin: Preclinical and clinical studies
    • BB Aggarwal A Kumar AC Bharti 2003 Anticancer potential of curcumin: preclinical and clinical studies Anticancer Res. 23 363 98
    • (2003) Anticancer Res. , vol.23 , pp. 363-98
    • Aggarwal, B.B.1    Kumar, A.2    Bharti, A.C.3
  • 47
    • 28544452918 scopus 로고    scopus 로고
    • Antioxidant and antiinflammatory activities of xanthorrhizol in hippocampal neurons and primary cultured microglia
    • CS Lim DQ Jin H Mok SJ Oh JU Lee JK Hwang 2005 Antioxidant and antiinflammatory activities of xanthorrhizol in hippocampal neurons and primary cultured microglia J Neurosci Res. 82 831 8
    • (2005) J Neurosci Res. , vol.82 , pp. 831-8
    • Lim, C.S.1    Jin, D.Q.2    Mok, H.3    Oh, S.J.4    Lee, J.U.5    Hwang, J.K.6
  • 49
    • 0023199491 scopus 로고
    • Lipid peroxide induced DNA damage: Protection by turmeric (Curcuma longa)
    • VK Shalini L Srinivas 1987 Lipid peroxide induced DNA damage: protection by turmeric (Curcuma longa) Mol Cell Biochem. 77 3 10
    • (1987) Mol Cell Biochem. , vol.77 , pp. 3-10
    • Shalini, V.K.1    Srinivas, L.2
  • 50
    • 0033253868 scopus 로고    scopus 로고
    • Antioxidative effects of turmeric, rosemary and capsicum extracts on membrane phospholipid peroxidation and liver lipid metabolism in mice
    • A Asai K Nakagawa T Miyazawa 1999 Antioxidative effects of turmeric, rosemary and capsicum extracts on membrane phospholipid peroxidation and liver lipid metabolism in mice Biosci Biotechnol Biochem. 63 2118 22
    • (1999) Biosci Biotechnol Biochem. , vol.63 , pp. 2118-22
    • Asai, A.1    Nakagawa, K.2    Miyazawa, T.3
  • 52
    • 0036027805 scopus 로고    scopus 로고
    • The curcuma antioxidants: Pharmacological effects and prospects for future clinical use. A review
    • J Miquel A Bernd JM Sempere J Diaz-Alperi A Ramirez 2002 The curcuma antioxidants: pharmacological effects and prospects for future clinical use. A review Arch Gerontol Geriatr. 34 37 46
    • (2002) Arch Gerontol Geriatr. , vol.34 , pp. 37-46
    • Miquel, J.1    Bernd, A.2    Sempere, J.M.3    Diaz-Alperi, J.4    Ramirez, A.5
  • 53
    • 0035208240 scopus 로고    scopus 로고
    • Superoxide anion and nitric oxide in high-grade esophagitis induced by acid and pepsin in rabbits
    • A Lanas F Soteras P Jimenez I Fiteni E Piazuelo Y Royo 2001 Superoxide anion and nitric oxide in high-grade esophagitis induced by acid and pepsin in rabbits Dig Dis Sci. 46 2733 43
    • (2001) Dig Dis Sci. , vol.46 , pp. 2733-43
    • Lanas, A.1    Soteras, F.2    Jimenez, P.3    Fiteni, I.4    Piazuelo, E.5    Royo, Y.6
  • 54
    • 59449090407 scopus 로고    scopus 로고
    • Superoxide anions produced by inflammatory cells play an important part in the pathogenesis of acid and pepsin induced oesophagitis in rabbits
    • Naya MJ, Pereboom D, Ortego J, Alda JO, Lanas A. Superoxide anions produced by inflammatory cells play an important part in the pathogenesis of acid and pepsin induced oesophagitis in rabbits. Gut. 1997;40175-81.
    • (1997) Gut. , vol.401 , pp. 75-81
    • Naya, M.J.1    Pereboom, D.2    Ortego, J.3    Alda, J.O.4    Lanas, A.5
  • 56
    • 34548827609 scopus 로고    scopus 로고
    • Chemoprevention of carcinogenic progression to esophageal adenocarcinoma by the manganese superoxide dismutase supplementation
    • RC Martin Q Liu JM Wo MB Ray Y Li 2007 Chemoprevention of carcinogenic progression to esophageal adenocarcinoma by the manganese superoxide dismutase supplementation Clin Cancer Res. 13 5176 82
    • (2007) Clin Cancer Res. , vol.13 , pp. 5176-82
    • Martin, R.C.1    Liu, Q.2    Wo, J.M.3    Ray, M.B.4    Li, Y.5
  • 57
    • 0034011261 scopus 로고    scopus 로고
    • Oxyradicals and DNA damage
    • LJ Marnett 2000 Oxyradicals and DNA damage Carcinogenesis. 21 361 70
    • (2000) Carcinogenesis. , vol.21 , pp. 361-70
    • Marnett, L.J.1
  • 58
    • 0028973482 scopus 로고
    • Requirement for generation of H2O2 for platelet-derived growth factor signal transduction
    • M Sundaresan ZX Yu VJ Ferrans K Irani T Finkel 1995 Requirement for generation of H2O2 for platelet-derived growth factor signal transduction Science. 270 296 9
    • (1995) Science. , vol.270 , pp. 296-9
    • Sundaresan, M.1    Yu, Z.X.2    Ferrans, V.J.3    Irani, K.4    Finkel, T.5
  • 60
    • 0028827252 scopus 로고
    • Dilated cardiomyopathy and neonatal lethality in mutant mice lacking manganese superoxide dismutase
    • Y Li TT Huang EJ Carlson S Melov PC Ursell JL Olson 1995 Dilated cardiomyopathy and neonatal lethality in mutant mice lacking manganese superoxide dismutase Nat Genet. 11 376 81
    • (1995) Nat Genet. , vol.11 , pp. 376-81
    • Li, Y.1    Huang, T.T.2    Carlson, E.J.3    Melov, S.4    Ursell, P.C.5    Olson, J.L.6
  • 61
    • 33745278897 scopus 로고    scopus 로고
    • Modulatory influence of dietary resveratrol during different phases of 1, 2-dimethylhydrazine induced mucosal lipid-peroxidation, antioxidant status and aberrant crypt foci development in rat colon carcinogenesis
    • M Sengottuvelan R Senthilkumar N Nalini 2006 Modulatory influence of dietary resveratrol during different phases of 1, 2-dimethylhydrazine induced mucosal lipid-peroxidation, antioxidant status and aberrant crypt foci development in rat colon carcinogenesis Biochim Biophys Acta. 1760 1175 83
    • (2006) Biochim Biophys Acta. , vol.1760 , pp. 1175-83
    • Sengottuvelan, M.1    Senthilkumar, R.2    Nalini, N.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.