Genetic analysis of salt-sensitive hypertension in Dahl rats reveals a link between cardiac fibrosis and high cholesterol

Cardiovascular Research

Volumn 81, Issue 3, 2009, Pages 618-626

  Wendt, Norbert ^a   Schulz, Angela ^a   Qadri, Fatimunnisa ^b   Bolbrinker, Juliane ^a   Kossmehl, Peter ^a   Winkler, Karl ^c   Stoll, Monika ^d   Vetter, Roland ^a   Kreutz, Reinhold ^a  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^b MAX DELBRÜCK CENTER FOR MOLECULAR MEDICINE   (Germany)

^c UNIVERSITY OF FREIBURG   (Germany)

^d Leibniz Institut fur Arterioskleroseforschung   (Germany)

Author keywords

Cardiac fibrosis; Genetics; Hypercholesterolemia; Hypertension; Inflammation; Salt sensitivity

Indexed keywords

CHOLESTEROL; COLLAGEN TYPE 1; FIBRONECTIN; LIPID; SODIUM CHLORIDE; TRIACYLGLYCEROL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BACTERIAL STRAIN; BLOOD LEVEL; CHOLESTEROL BLOOD LEVEL; CHOLESTEROL DIET; CHROMOSOME 19; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DIET; FEMALE; FIBROSING ALVEOLITIS; GENETIC ANALYSIS; HEART MUSCLE FIBROSIS; HEART WEIGHT; HYPERCHOLESTEROLEMIA; HYPERTENSION; IMMUNOHISTOCHEMISTRY; LIPID BLOOD LEVEL; MALE; NONHUMAN; PARAMETER; PRIORITY JOURNAL; RAT; RAT STRAIN; SEX; SPONTANEOUSLY HYPERTENSIVE RAT; STATISTICAL SIGNIFICANCE; SYSTOLIC BLOOD PRESSURE; TARGET ORGAN; TISSUE; TRIACYLGLYCEROL BLOOD LEVEL; VASCULAR FIBROSIS; WEIGHT;

ANIMALS; BLOOD PRESSURE; CHOLESTEROL; COLLAGEN TYPE I; DISEASE MODELS, ANIMAL; FEMALE; FIBRONECTINS; FIBROSIS; GENETIC PREDISPOSITION TO DISEASE; HYPERCHOLESTEROLEMIA; HYPERTENSION; MALE; MYOCARDIUM; PHENOTYPE; QUANTITATIVE TRAIT LOCI; RATS; RATS, INBRED DAHL; RATS, INBRED SHR; RATS, TRANSGENIC; SEX FACTORS; SODIUM CHLORIDE, DIETARY; UP-REGULATION; VENTRICULAR DYSFUNCTION, LEFT;

EID: 59449100088     PISSN: 00086363     EISSN: 17553245     Source Type: Journal    
DOI: 10.1093/cvr/cvn263     Document Type: Article

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