Management and successful desensitization in methotrexate-induced anaphylaxis

Pediatric Blood and Cancer

Volumn 52, Issue 2, 2009, Pages 295-297

  Bouchireb, Karim ^a   Dodille, Aurélie ^a   Ponvert, Claude ^b   Gouraud, François ^c   Dubrel, Marie ^a   Brugières, Laurence ^a  

^a INSTITUT GUSTAVE ROUSSY   (France)

^b Pulmonology and Allergy Unit   (France)

^c Hospital   (France)

Author keywords

Anaphylaxis; Desensitization; Methotrexate

Indexed keywords

DEXAMETHASONE; DIPHENHYDRAMINE; ETOPOSIDE; FOLINIC ACID; IFOSFAMIDE; METHOTREXATE;

ANAMNESIS; ANAPHYLAXIS; ARTICLE; CANCER CHEMOTHERAPY; CANCER SURGERY; CARDIOVASCULAR SYMPTOM; CASE REPORT; CHILD; CLINICAL FEATURE; DESENSITIZATION; DRUG BLOOD LEVEL; DRUG DOSE INCREASE; DRUG DOSE REDUCTION; DRUG MEGADOSE; DRUG TOLERABILITY; DRUG WITHDRAWAL; FEMALE; HUMAN; METASTASIS; MULTIPLE CYCLE TREATMENT; OSTEOSARCOMA; PRIORITY JOURNAL; RESPIRATORY TRACT DISEASE; SCHOOL CHILD; SKIN TEST; URTICARIA; CHEMICALLY INDUCED DISORDER; DRUG HYPERSENSITIVITY; METHODOLOGY;

ANAPHYLAXIS; CHILD; DESENSITIZATION, IMMUNOLOGIC; DRUG HYPERSENSITIVITY; HUMANS; METHOTREXATE; OSTEOSARCOMA;

EID: 59449098829     PISSN: 15455009     EISSN: 15455017     Source Type: Journal    
DOI: 10.1002/pbc.21742     Document Type: Article

References (20)

1. al-Lamki Z, Thomas E, el-Banna N, et al. Acute urticaria and hepatitis complicating high-dose methotrexate therapy. Med Pediatr Oncol 1995;24:137-140.
2. Alkins SA, Byrd JC, Morgan SK, et al. Anaphylactoid reactions to methotrexate. Cancer 1996;77:2123-2126.
3. Caldeira T, Costa V, Silva I, et al. Anaphylactoid reaction to high-dose methotrexate and re-administration after a successful desensitization. Pediatr Hematol Oncol 2008;25:131-134.
4. Davis KA, Williams P, Walker JC. Successful desensitization to high-dose methotrexate after systemic anaphylaxis. Ann Allergy Asthma Immunol 2003;90:87-89.
5. Devecioglu O, Biner B, Karabocuoglu M, et al. Systemic near-fatal anaphylactic reaction after intrathecal methotrexate administration. Med Pediatr Oncol 2000;34:151-152.
6. Elkiran ET, Altundag K, Aksoy S, et al. Systemic anaphylactic reaction following intrathecal administration of methotrexate in adult patient with primary central nervous system lymphoma. Am J Hematol 2004;75:265.
7. Goldberg NH, Romolo JL, Austin EH, et al. Anaphylactoid type reactions in two patients receiving high dose intravenous methotrexate. Cancer 1978;41:52-555.
8. Kohli A, Ferencz TM, Calderon JG. Readministration of high-dose methotrexate in a patient with suspected immediate hypersensitivity and T-cell acute lymphoblastic lymphoma. Allergy Asthma Proc 2004;25:249-252.
9. Lluch-Bernal M, Cuesta-Herranz J, De las Heras M, et al. Anaphylactic reaction to methotrexate. Allergy 1997;52:1150-1151.
10. Lobelle C, Lopez Rivas M, Barreiro J, et al. Anaphylactic reaction to high-dose methotrexate. Pediatr Hematol Oncol 1995;12:213-214.
11. MacGinnitie AJ, Walensky LD, Turvey SE, et al. Management of an anaphylactoid reaction to methotrexate with a stepwise graded challenge. Pediatr Allergy Immunol 2003;14:409-411.
12. Postovsky S, Elhasid R, Ben-Barak A, et al. Allergic reaction to high-dose methotrexate. Med Pediatr Oncol 2000;35:131-132.
13. Straka M, Zeringue E, Goldman M. A rare drug reaction to methotrexate after treatment for ectopic pregnancy. Obstet Gynecol 2004;103:1047-1048.
14. Vega A, Cabanas R, Contreras J, et al. Anaphylaxis to methotrexate: A possible IgE-mediated mechanism. J Allergy Clin Immunol 1994;94:268-270.
15. Le Deley MC, Guinebretiere JM, Gentet JC, et al. SFOP OS94: A randomised trial comparing preoperative high-dose methotrexate plus doxorubicin to high-dose methotrexate plus etoposide and ifosfamide in osteosarcoma patients. Eur J Cancer 2007;43:752-761.
16. Gluck-Kuyt I, Irwin LE. Anaphylactic reaction to high-dose methotrexate. Cancer Treat Rep 1979;63:797-798.
17. Woolley PV III, Sacher RA, Priego VM, et al. Methotrexate-induced immune haemolytic anaemia. Br J Haematol 1983;54:543-552.
18. Recker DP, Minor JR, Miller FW. Successful prevention of an anaphylactoid reaction to high-dose methotrexate. DICP 1989;23:1032.
19. Woessmann W, Seidemann K, Mann G, et al. The impact of the methotrexate administration schedule and dose in the treatment of children and adolescents with B-cell neoplasms: A report of the BFM group study NHL-BFM95. Blood 2005;105:948-9958.
20. Keefe DA, Capizzi RL, Rudnick SA. Methotrexate cytotoxicity for l5178y/asn- lymphoblasts: Relationship of dose and duration of exposure to tumor cell viability. Cancer Res 1982;42:1641-1645.